Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie最新文献

{"title":"Validation of a mathematical-geometrical model to calculate the length of an individual anterior arch.","authors":"Eva Paddenberg, Raphael Heiß, Tobias Grünbaum, Peter Proff, Christian Kirschneck","doi":"10.1007/s00056-023-00482-2","DOIUrl":"10.1007/s00056-023-00482-2","url":null,"abstract":"<p><strong>Purpose: </strong>For resolving anterior dental crowding or spacing, it is of key interest in personalised orthodontic diagnostics and treatment planning to predict the extent of space gained or lost in the anterior dental arch by changing incisor inclination or position. To facilitate the determination of anterior arch length (AL) and to predict its alterations following tooth movements, a mathematical-geometrical model, based on a third-degree parabola, was established. The aim of this study was to validate this model and assess its diagnostic precision.</p><p><strong>Methods: </strong>This retrospective diagnostic study evaluated 50 randomly chosen dental casts taken before (T0) and after (T1) orthodontic treatment with fixed appliances. Plaster models were digitally photographed, allowing two-dimensional digital measurements of arch width, depth and length. A computer programme based on the mathematical-geometrical model to be validated was created to calculate AL for any given arch width and depth. Mean differences and correlation coefficients as well as Bland-Altman plots were used to compare the measured and the calculated (predicted) AL, evaluating the precision of the model.</p><p><strong>Results: </strong>Inter- and intrarater reliability tests showed reliable measurements of arch width, depth and length. Measured and calculated (predicted) AL revealed high concordance according to concordance correlation coefficient (CCC), intraclass correlation coefficient (ICC), and Bland-Altman analyses and negligible differences between the mean values.</p><p><strong>Conclusions: </strong>The mathematical-geometrical model calculated anterior AL without significant difference to the measured AL, indicating its validity. The model can thus be used clinically for predicting alterations of AL following therapeutic changes of incisor inclination/position.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"108-118"},"PeriodicalIF":1.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11861399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9748040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of conventional two-dimensional and digital three-dimensional imaging in orthodontics : A systematic review and meta-analysis.","authors":"Ana-Maria Haude, Thomas Lehmann, Christoph-Ludwig Hennig, Collin Jacobs","doi":"10.1007/s00056-024-00574-7","DOIUrl":"https://doi.org/10.1007/s00056-024-00574-7","url":null,"abstract":"<p><strong>Objectives: </strong>Digital imaging techniques are important in dental diagnostics and therapy planning. Thus, the goal was to investigate the current state of the science regarding two- (2D) and three-dimensional (3D) imaging for clinical orthodontic issues via a systematic literature review and meta-analysis.</p><p><strong>Materials and methods: </strong>Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, the search was carried out using common electronic databases with the following terms: cbct AND opt AND dentistry, cbct AND opt AND orthodontics, cbct AND opt, three-dimensional imaging AND two-dimensional imaging AND orthodontics, cbct AND lateral cephalogram. A forest plot was utilized to depict the standardized mean differences (SMD) using a random-effects model to account for study heterogeneity. Heterogeneity assessment of the various trials was conducted using the I²-value and the Q‑test.</p><p><strong>Results: </strong>Of the 362 articles (1987-2023) identified, 41 articles met the inclusion criteria. The studies were categorized into four groups based on clinical background: mini-implant placement, root resorptions, impacted canines and cephalometric measurements. For mini-implant placement, 4 papers explored the benefits of 3D imaging. Root resorption detection was the focus of 4 studies, while 8 articles investigated 3D diagnostics for impacted canines. Overall, while 2D imaging suffices for evaluating mini-implant placement, CBCT images offer enhanced accuracy for investigating root resorptions and improved sensitivity in identifying impacted canines. Comparability of 2D and 3D imaging, with a focus on cephalometric measurements, was evaluated in 25 studies. Within this group, 10 papers were included in a meta-analysis, comparing SNA, SNB and ANB angle measurements. The random-effects model was used to compare the results of the SNA, SNB and ANB angles, which were presented in forest plots. No significant differences were found in the comparison of 2D and 3D imaging techniques for the SNA angle (p = 0.338; SMD = 0.39; 95% CI -0.40 to 1.18), the SNB angle (p = 0.650; SMD = 0.11; 95% CI -0.35 to 0.57), and the ANB angle (p = 0.666; SMD 0.89; 95% CI -0.32 to 0.50), whereby heterogeneity was high for all (I² = 90.27%, p < 0.001, I² = 76.81%, p = 0.004, and I² = 93.29%, p < 0.001, respectively).</p><p><strong>Conclusion: </strong>Based on the findings and the additional meta-analysis, 3D imaging is either equivalent or potentially superior to conventional 2D imaging for all subgroups. Further studies are required.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of three-dimensionally printed retainers and aligners : A systematic review.","authors":"Hui Shan Boo, Saritha Sivarajan, Norhidayah Nor Zahidah Mohd Tahir, Aufa Dahlia Bahar","doi":"10.1007/s00056-024-00570-x","DOIUrl":"https://doi.org/10.1007/s00056-024-00570-x","url":null,"abstract":"<p><strong>Background: </strong>With the constant improvement of photopolymerizable resin, direct three-dimensional (3D) printing of retainers and aligners (R&A) has gained popularity in recent years. The primary objective of this research was to systematically evaluate the evidence regarding the accuracy of 3D-printed R&A in terms of trueness and precision (T&P).</p><p><strong>Methods: </strong>Electronic database searches were performed on PubMed, Science Direct, Web of Science, Scopus, Ovid, and Clinicaltrial.gov through 17 November 2023. The Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool was used to assess the risk of bias and applicability concerns of the methodologic quality of the articles.</p><p><strong>Results: </strong>A total of 12 in vitro studies were selected. Five studies reported the accuracy of 3D-printed retainers and another seven reported on aligners. For the 3D-printed retainer group, only Naeem et al. [1] reported both T&P and found that stereolithography (SLA) and PolyJet photopolymer (PPP) printers demonstrated higher accuracy than digital light processing (DLP) and continuous digital light processing (cDLP) printers. For the 3D-printed aligners group, only Koenig et al. [2] reported both T&P and found that 3D-printed aligners fabricated with photopolymerizable polyurethane resin demonstrated higher trueness (0.14 ± 0.020 mm) compared to conventional thermoformed aligners (0.188 ± 0.074 and 0.209 ± 0.094).</p><p><strong>Conclusion: </strong>The existing digital workflow involving various printing materials, angulations, printing thickness, and printing technologies is feasible for the fabrication of direct 3D printing of R&A with variable degrees of accuracy. Most techniques worked within the clinically acceptable level of accuracy of 0.25 mm.</p><p><strong>Trial registration number: </strong>PROSPERO CRD 42022312907.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional localization of tooth germs without ionizing radiation : Proof-of-concept study using magnetic resonance imaging.","authors":"Andreas Detterbeck, Thomas Huber, Matthias Schmid","doi":"10.1007/s00056-024-00575-6","DOIUrl":"https://doi.org/10.1007/s00056-024-00575-6","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the feasibility and accuracy of using magnetic resonance imaging (MRI) for the three-dimensional (3D) localization of tooth germs. A MRI 3D dataset was compared to a cone-beam computed tomography (CBCT) dataset, which is the current gold standard method in the localization of tooth germs. In this proof-of-concept study, the potential of eliminating the exposure of patients to ionizing radiation for tooth germ localization was evaluated.</p><p><strong>Methods: </strong>A halved pig head (Sus scrofa domestica) was imaged with MRI and CBCT. The MRI data were manually segmented using InVesalius 3.1.1 (Centro de Tecnologia da Informação Renato Archer, Campinas, Brazil) to generate a 3D model, later processed in OnyxCeph3™ (Image Instruments GmbH, Chemnitz, Germany). The CBCT data were directly imported into OnyxCeph3™ for processing. Both datasets were combined with intraoral scans, and 12 raters took measurements to compare the ability to localize tooth germs with the help of the two modalities.</p><p><strong>Results: </strong>A total of 144 measurements were obtained (2 modalities × 6 measurement sections × 12 raters). The interrater reliability was high (intraclass correlation coefficients [ICCs] ≥ 0.99 for both modalities). The average differences between CBCT and MRI measurements ranged between -0.43 mm (Bonferroni-Holm-corrected 90% confidence interval [-0.69 mm, -0.16 mm]) and 0.48 mm [0.34 mm, 0.63 mm] and were equivalent with respect to a margin of -1 mm to 1 mm in all measurement sections (Bonferroni-Holm-corrected P < 0.01 in all sections).</p><p><strong>Conclusion: </strong>MRI demonstrates high potential as a nonionizing alternative to CBCT for 3D localization of impacted and displaced teeth, particularly in children and adolescents. The fluid-filled dental follicle provides excellent contrast in MRI, aiding precise localization. Future clinical studies with larger sample sizes are essential for validation.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143366407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of malocclusion and orthodontic treatment on quality of life among orthodontic patients with craniofacial disorder compared to healthy controls : A cross-sectional study.","authors":"C Weismann, M Schmidt, J Effert, M C Schulz, C F Poets, B Koos, M Aretxabaleta","doi":"10.1007/s00056-024-00571-w","DOIUrl":"https://doi.org/10.1007/s00056-024-00571-w","url":null,"abstract":"<p><strong>Purpose: </strong>Craniofacial disorders (CD) affect the Oral Health Impact Profile (OHIP). Therefore, this study evaluates the OHIP in orthodontic patients with cleft lip and/or palate or Robin sequence compared to healthy controls (C).</p><p><strong>Methods: </strong>A prospective, cross-sectional study was conducted. Oral health-related quality of life (OHRQoL) was assessed using the OHIP-14 questionnaire, with responses categorized into functional and psychological well-being items. In addition, the study considered the influence of crossbite, orthodontic appliance type, oral hygiene, and speech therapy. A high OHIP score represents a good quality of life. The Mann-Whitney test was used for nonparametric quantitative variables; statistical significance was set at p < 0.05.</p><p><strong>Results: </strong>The study included 119 participants (ages 7-21 years; 61 male, 58 female), divided into a CD group consisting of patients with cleft lip and/or palate or Robin sequence (n = 42) and a control group (C; n = 77; mean age 13.5 ± 5.2 and 14.3 ± 3.3 years, respectively). Both groups showed comparable OHIP-14 scores. The CD group reported significantly higher satisfaction regarding nutritional intake (p = 0.03), while the social and psychological dimensions were reduced (p = 0.04). Factors like crossbite, orthodontic appliance and speech therapy did not have a significant impact on OHIP. CD patients with good oral hygiene showed significantly superior self-reported psychological OHIP (p = 0.04).</p><p><strong>Conclusion: </strong>Patients with cleft lip and/or palate or with Robin sequence exhibited OHIP scores comparable to healthy individuals despite their underlying condition. Early guidance on dental care and tooth-friendly nutrition has the potential to improve OHRQoL. Additionally, providing supplemental psychological support during orthodontic treatment is advisable.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The IL-17 level in gingival crevicular fluid as an indicator of orthodontically induced inflammatory root resorption.","authors":"Honghong Zhang, Lufei Wang, Aipeng Liu, Hua Zhou, Xiao Liang, Na Kang","doi":"10.1007/s00056-024-00573-8","DOIUrl":"https://doi.org/10.1007/s00056-024-00573-8","url":null,"abstract":"<p><strong>Purpose: </strong>Interleukin (IL)-17 expression in the periodontal ligament is associated with orthodontically induced inflammatory root resorption (OIIRR). Seeking a convenient, rapid, and non-invasive IL-17 detection approach could help predict OIIRR. In this study, we assessed the potential of the IL-17 level in gingival crevicular fluid (GCF) to be an indicator of OIIRR.</p><p><strong>Methods: </strong>To enable tooth movement, 8‑ to 10-week-old male Wistar rats were subjected to 20 g/60 g orthodontic force for up to 14 days. GCF and peripheral blood were collected for the IL-17 enzyme-linked immunosorbent assay (ELISA). Histological changes and the expression of IL-17, receptor activator of nuclear factor κB ligand (RANKL), and osteoprotegerin (OPG) in periodontal tissue were evaluated by hematoxylin-eosin and immunohistochemistry staining, respectively. Osteoclasts were visualized by tartrate-resistant acid phosphatase (TARP) staining.</p><p><strong>Results: </strong>GCF IL-17 level rapidly rose in the early phase of orthodontic loading, accompanied by bone and tooth root destruction. At the later stage, the GCF IL-17 level gradually decreased, while the inflammatory destruction was reduced and the periodontal tissue began to repair. GCF IL-17 expression generally tended to be coincident with the periodontal tissue reaction: GCF IL-17 was robustly correlated to the RANKL/OPG ratio (r_s = 0.72, p = 0.002) or osteoclast number (r_s = 0.84, p < 0.001). Additionally, the GCF IL-17 level was correlated to serum IL-17 (r_s = 0.61, p = 0.016) or periodontal IL-17 (r_s = 0.84, p < 0.001).</p><p><strong>Conclusion: </strong>The IL-17 level in GCF during orthodontic treatment is associated with OIIRR and, thus, could be an early indicator for developing OIIRR. The advantages of being a convenient, rapid, and non-invasive GCF IL-17 measurement make it a promising method for early detection of OIIRR.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new harmony box supplemented with gonial angle and age based on a growing Swiss population.","authors":"Nele Lorenz, Despina Koletsi, Raphael Patcas, Rebecca Jungbauer, Vasiliki Koretsi","doi":"10.1007/s00056-024-00569-4","DOIUrl":"https://doi.org/10.1007/s00056-024-00569-4","url":null,"abstract":"<p><strong>Purpose: </strong>The scope of the present study was to create a new harmony box by adding two diagnostically and clinically important cephalometric variables, the gonial and interincisal angles, while also considering the effect of sex and age for a growing Swiss population.</p><p><strong>Methods: </strong>A healthy sample with an overjet and overbite between 2 and 4 mm, and 1.5 and 4.5 mm, respectively, of the Zurich Craniofacial Growth Study was considered. Pairwise correlations between the cephalometric angles were evaluated with the Pearson correlation coefficient (r). Regression models were built for each cephalometric variable serving as the dependent one. The Akaike Information Criterion and the Bayesian Information Criterion were used to structure and select the final multivariable regression model. Bland-Altman plots and the Lin's concordance correlation coefficient were used to assess inter- and intraexaminer agreement.</p><p><strong>Results: </strong>The sample consisted of 301 individuals with a mean age of 13.4 years. Measurement concordance was confirmed both within and between examiners. The strongest correlations were observed between the angles SNB and SNA (r = 0.81), ArGoMe and SN-ML (r = 0.57), and SN-ML and SNB (r = 0.56). The SNB angle qualified as the dependent variable in the multivariable regression that framed the newly provided harmony box, with the predictor variables age (p < 0.001) and the angles SNA (p < 0.001), SN-ML (p < 0.001), SN-NL (p = 0.005), NSBa (p = 0.001), and ArGoMe (p < 0.001). The interincisal angle did not increase the robustness of the model and was excluded (p > 0.05).</p><p><strong>Conclusion: </strong>Contrary to the interincisal angle, gonial angle and age qualified for inclusion in the new harmony box for individualized cephalometrics in a sample of healthy schoolchildren from Zurich, Switzerland.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dentoalveolar alterations after interventions to relieve mouth breathing : Systematic review and meta-analysis.","authors":"Rizomar Ramos do Nascimento, Daniele Masterson, Claudia Trindade Mattos, Oswaldo de Vasconcellos Vilella","doi":"10.1007/s00056-024-00568-5","DOIUrl":"https://doi.org/10.1007/s00056-024-00568-5","url":null,"abstract":"<p><strong>Background: </strong>Mouth breathing is related to morphological and functional alterations in growing individuals. Understanding early events that can lead to these changes can prevent or decrease the need for orthodontic treatment.</p><p><strong>Objective: </strong>The goal was to assess the prognosis for dental alterations evidenced by changes in the incisor inclination and arch width after surgical intervention to normalize the mode of breathing in growing patients.</p><p><strong>Data sources: </strong>Databases were searched based on the guidelines of the Preferred Report Items for Systematic Reviews and Meta-Analysis (PRISMA statement), with no restrictions on language or year of publication.</p><p><strong>Study selection: </strong>Seven non-randomized studies were selected, with follow-up times ranging from 12 to 60 months. Differences in the inclination of the upper and lower incisors, intercanine and intermolar maxillary widths between the initial and final measurements were the primary and second outcomes.</p><p><strong>Data extraction: </strong>Two independent authors extracted the data independently. The Quality in Prognosis Studies tool (QUIPS tool) and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) were used to assess the risk of bias and the quality of evidence.</p><p><strong>Data synthesis: </strong>Although four studies presented a similar methodology and significant results regarding incisor inclination, the meta-analysis did not provide statistical evidence favoring surgical interventions for these variables (p = 0.12). No significant changes in the transverse dimension of the maxillary arch were found in the primary dentition (95% confidence interval [CI], 0.231 [-0.394/0.857], p = 0.4690).</p><p><strong>Conclusions: </strong>Four separate studies provided acceptable but low evidence that interventions to relieve mouth breathing in growing individuals favor normalization of lower incisor inclination. In the primary dentition, no significant changes were found in the arch width.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methylphenidate-effects on orthodontic tooth movement, orthodontically induced and nonorthodontic root resorption? : A micro-computed tomography and immunohistochemical analysis.","authors":"Burak Akce, Gulay Dumanli Gok, Sibel Demirci Delipinar, Islim Kaleler","doi":"10.1007/s00056-024-00567-6","DOIUrl":"https://doi.org/10.1007/s00056-024-00567-6","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to examine the effect of methylphenidate, prescribed for individuals with attention deficit hyperactivity disorder (ADHD), on orthodontic tooth movement (OTM) and root resorption.</p><p><strong>Methods: </strong>In all, 30 rats were divided into (1) control (C), (2) constant (MCD), and (3) increasing dose of methylphenidate (MID) groups and 2 subgroups for each of them (nonorthodontic (30 days)/orthodontic (44 days)). After receiving saline or methylphenidate for 30 days, rats in the nonorthodontic groups were euthanized (n = 5/group). Subsequently, 50 g of orthodontic force was applied to the remaining rats' first molars for 14 days (orthodontic groups). Quantitative micro-computed tomography (micro-CT) and immunohistochemical analyses were conducted. For statistical analyses Kruskal-Wallis and Dunnet tests were applied with a significance set at p < 0.05.</p><p><strong>Results: </strong>Micro-CT analysis demonstrated a statistically significant increase in tooth displacement with higher doses of methylphenidate compared to control and lower-dose groups, though no significant difference was detected between MID-44 and MCD-44 groups. Orthodontic force led to a significant increase in root resorption, peaking in the coronal region and diminishing toward the apex. The highest amount of resorption was observed in the MID groups, with a significant difference between nonorthodontic MID-30 and C‑30 groups. No significant changes in bone parameters were noted in the tension zone, but numerical reductions in trabecular thickness (Tb.Th), bone volume fraction (BV/TV), and bone mineral density (BMD) were observed. In nonorthodontic cohorts, VEGF and RANK levels were significantly elevated in the MID-30 group, along with increased TRAP expression, indicating bone resorption. Orthodontic cohorts exhibited a significant increase in RANK- and TRAP-positive cells with methylphenidate administration. Reductions in OPG and elevations in RANK, RANKL, VEGF, and TRAP were noted, primarily between orthodontic and nonorthodontic groups.</p><p><strong>Conclusion: </strong>The present rat model suggests a weak potential for methylphenidate to increase root resorption. However, increased doses of methylphenidate accelerated OTM.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of different debonding and reconditioning methods for orthodontic ceramic brackets regarding effectiveness for reuse : An in vitro study.","authors":"Katharina Grosch, Jörg Meister, Sanjay D Raval, Ahmed Mahmoud Fouda, Christoph Bourauel","doi":"10.1007/s00056-023-00469-z","DOIUrl":"10.1007/s00056-023-00469-z","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the reusability of ceramic brackets in terms of shear bond strength, friction behavior, slot dimension, fracture strength, and color stability.</p><p><strong>Methods: </strong>A total of 90 conventionally debonded and 30 by an Er:YAG laser debonded ceramic brackets were collected. All the used brackets were inspected under a stereomicroscope at 18 × magnification and sorted according to their adhesive remnant index (ARI). Five groups were formed (n = 10): (1) new brackets as a control group, (2) flamed and sandblasted, (3) flamed and acid bathed, (4) laser-reconditioned, and (5) laser-debonded brackets. The bracket groups were tested regarding different properties such as shear bond strength, friction behavior, slot size, fracture strength, and color stability. Analysis of variance (ANOVA) and nonparametric Kruskal-Wallis tests were used for statistical analysis (significance level: p < 0.05).</p><p><strong>Results: </strong>Shear bond strength values of the acid reconditioned brackets were significantly lower (8.0 ± 3.1 MPa) compared to the control group (12.9 ± 2.9 MPa). Laser-reconditioned (32.8 ± 2.7%) and laser-debonded (30.9 ± 2.4%) brackets showed the lowest force loss due to friction (control group 38.3 ± 3.0%). No significant differences were observed between groups regarding slot size and fracture strength. All groups had color differences of <math> <msubsup><mrow><mo>∆</mo> <mi>E</mi></mrow> <mrow><mi>a</mi> <mi>b</mi></mrow> <mi>*</mi></msubsup> </math> < 10. Scanning electron microscope images and ARI scores indicated that most of the residues on the bracket bases were removed.</p><p><strong>Conclusion: </strong>All reconditioning methods yielded adequate results regarding bracket properties. Yet, focusing on the need to protect the enamel and the bracket base, laser debonding seems to be the most suitable method for reconditioning ceramic brackets.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"11-23"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9634122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}