PathologePub Date : 2022-02-01DOI: 10.1007/s00292-021-01050-4
{"title":"Mitteilungen der Deutschen Gesellschaft für Pathologie.","authors":"","doi":"10.1007/s00292-021-01050-4","DOIUrl":"https://doi.org/10.1007/s00292-021-01050-4","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"83-85"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathologePub Date : 2022-02-01Epub Date: 2021-12-23DOI: 10.1007/s00292-021-01041-5
Drolaiz Liu, Rupert Langer
{"title":"[Grading of tumor regression of gastrointestinal carcinomas after neoadjuvant therapy].","authors":"Drolaiz Liu, Rupert Langer","doi":"10.1007/s00292-021-01041-5","DOIUrl":"https://doi.org/10.1007/s00292-021-01041-5","url":null,"abstract":"<p><p>Pre- or perioperative chemo- or radiochemotherapy and subsequent resection is the standard therapy for locally advanced esophageal, gastric, and rectal cancer. A tumor regression grading (TRG; also tumor regression grade) categorizes the extent of the regressive changes after a neoadjuvant treatment. There are several TRG systems for gastrointestinal carcinomas that relate either to the extent of the therapy-induced fibrosis in relation to the residual tumor or the estimated proportion of the residual tumor in the area of the former tumor area. An ideal TRG system shows significant interobserver agreement and offers relevant prognostic information - in most cases a complete or almost complete regression after neoadjuvant therapy is associated with an improved prognosis. In this review, the most commonly used TRG systems for gastrointestinal carcinomas are presented and discussed. In addition, current issues such as the standardization of TRG and the subject of regression in lymph node metastases in the context of a TRG system are discussed.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"51-56"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39628305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathologePub Date : 2022-02-01Epub Date: 2022-01-04DOI: 10.1007/s00292-021-01038-0
Thomas Longerich, Peter Schirmacher
{"title":"[Pathology of hepatocellular carcinoma].","authors":"Thomas Longerich, Peter Schirmacher","doi":"10.1007/s00292-021-01038-0","DOIUrl":"https://doi.org/10.1007/s00292-021-01038-0","url":null,"abstract":"<p><p>Hepatocellular carcinoma (HCC) represents the third leading cause of cancer-related mortality worldwide and has a well-defined etiology. It develops in a stepwise process with morphologically defined precursor lesions. Typing of highly differentiated hepatocellular tumors is supported by immunohistological marker panel and the so-called matrix diagnosis. The recent World Health Organization (WHO) classification defined morpho-molecular HCC subtypes showing typical clinical and prognostic characteristics. If HCC subtyping is considered in future clinical studies of advanced HCC, this could help to introduce personalized HCC therapy. Currently, precision oncology is not available for HCC.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"67-78"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39872997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathologePub Date : 2022-02-01Epub Date: 2022-01-25DOI: 10.1007/s00292-021-01045-1
Wilfried Roth, Matthias Gaida
{"title":"[Two new sections: \"Molecular Tumor Board\" and \"Picture of the Month\"].","authors":"Wilfried Roth, Matthias Gaida","doi":"10.1007/s00292-021-01045-1","DOIUrl":"https://doi.org/10.1007/s00292-021-01045-1","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathologePub Date : 2022-02-01DOI: 10.1007/s00292-021-01043-3
{"title":"Mitteilungen der IAP.","authors":"","doi":"10.1007/s00292-021-01043-3","DOIUrl":"https://doi.org/10.1007/s00292-021-01043-3","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"79-82"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathologePub Date : 2022-02-01Epub Date: 2022-01-25DOI: 10.1007/s00292-021-01048-y
Heike I Grabsch, Rupert Langer, Michael Vieth
{"title":"[Spring symposium pathology of the gastrointestinal tract].","authors":"Heike I Grabsch, Rupert Langer, Michael Vieth","doi":"10.1007/s00292-021-01048-y","DOIUrl":"https://doi.org/10.1007/s00292-021-01048-y","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"5-7"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathologePub Date : 2022-02-01DOI: 10.1007/s00292-021-01047-z
{"title":"Dank an die Gutachter*innen von Der Pathologe.","authors":"","doi":"10.1007/s00292-021-01047-z","DOIUrl":"https://doi.org/10.1007/s00292-021-01047-z","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39828927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathologePub Date : 2021-12-01Epub Date: 2021-10-20DOI: 10.1007/s00292-021-01007-7
Alfons Hofstetter
{"title":"[Dr. med. Ernst Keiditsch (4 June 1936-22 July 2021) : Head Emeritus of the Department of Pathology, Municipal Hospital of Munich-Bogenhausen].","authors":"Alfons Hofstetter","doi":"10.1007/s00292-021-01007-7","DOIUrl":"https://doi.org/10.1007/s00292-021-01007-7","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":" ","pages":"216-217"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39535977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PathologePub Date : 2021-12-01Epub Date: 2021-11-25DOI: 10.1007/s00292-021-01026-4
Till Braunschweig, Katrin Schierle
{"title":"[Report of the History and Ethics of Pathology Working Group : Virtual working group meeting during the Virtual Pathology Days of the German Society of Pathology (ViPa2021), 9 June 2021].","authors":"Till Braunschweig, Katrin Schierle","doi":"10.1007/s00292-021-01026-4","DOIUrl":"https://doi.org/10.1007/s00292-021-01026-4","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":" ","pages":"180-181"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39658158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}