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[The molecular pathology breviary: read depth and coverage in NGS analysis]. [分子病理学简章：阅读NGS分析的深度和覆盖面]。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2021-10-13 DOI: 10.1007/s00292-021-01009-5
Ulrich Lehmann, Albrecht Stenzinger
{"title":"[The molecular pathology breviary: read depth and coverage in NGS analysis].","authors":"Ulrich Lehmann, Albrecht Stenzinger","doi":"10.1007/s00292-021-01009-5","DOIUrl":"10.1007/s00292-021-01009-5","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"65-66"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39513639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Standardized structured reports for gastrointestinal tumors]. 【胃肠肿瘤标准化结构化报告】。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2021-10-05 DOI: 10.1007/s00292-021-00986-x
Ekkehard Hewer, Anna Rump, Rupert Langer
{"title":"[Standardized structured reports for gastrointestinal tumors].","authors":"Ekkehard Hewer,&nbsp;Anna Rump,&nbsp;Rupert Langer","doi":"10.1007/s00292-021-00986-x","DOIUrl":"https://doi.org/10.1007/s00292-021-00986-x","url":null,"abstract":"<p><p>Synoptic reporting in pathology as opposed to traditional narrative reporting is defined by a laboratory value-like format and use of standardized checklists. It contributes to completeness and comprehensibility of pathology reports and ultimately patient care. As of today, two major institutions publish synoptic reporting templates, the College of American Pathologists (CAP) and the International Collaboration for Cancer Reporting (ICCR). Synoptic protocols are available for all major cancer types and provide not only a standardized terminology and a checklist for completeness of reports, but also facilitate uniform utilization of diagnostic criteria. Additionally, both CAP and ICCR protocols are accompanied by detailed and up-to-date reference lists and thereby represent a valuable source of information even when synoptic reporting is not used. The benefits and challenges of implementation of synoptic reporting are discussed, in particular with regard to reporting in German.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39488449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum zu: Standardisierte strukturierte Befundberichte gastrointestinaler Tumoren. 导致了对肠胃手术的标准化组织结构图
4区 医学
Pathologe Pub Date : 2022-02-01 DOI: 10.1007/s00292-021-01020-w
Ekkehard Hewer, Anna Rump, Rupert Langer
{"title":"Erratum zu: Standardisierte strukturierte Befundberichte gastrointestinaler Tumoren.","authors":"Ekkehard Hewer,&nbsp;Anna Rump,&nbsp;Rupert Langer","doi":"10.1007/s00292-021-01020-w","DOIUrl":"https://doi.org/10.1007/s00292-021-01020-w","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"63-64"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39658156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitteilungen der Deutschen Gesellschaft für Pathologie. 德国病理学协会的信息
4区 医学
Pathologe Pub Date : 2022-02-01 DOI: 10.1007/s00292-021-01050-4
{"title":"Mitteilungen der Deutschen Gesellschaft für Pathologie.","authors":"","doi":"10.1007/s00292-021-01050-4","DOIUrl":"https://doi.org/10.1007/s00292-021-01050-4","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"83-85"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Grading of tumor regression of gastrointestinal carcinomas after neoadjuvant therapy]. 【胃肠癌新辅助治疗后肿瘤消退的分级】。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2021-12-23 DOI: 10.1007/s00292-021-01041-5
Drolaiz Liu, Rupert Langer
{"title":"[Grading of tumor regression of gastrointestinal carcinomas after neoadjuvant therapy].","authors":"Drolaiz Liu,&nbsp;Rupert Langer","doi":"10.1007/s00292-021-01041-5","DOIUrl":"https://doi.org/10.1007/s00292-021-01041-5","url":null,"abstract":"<p><p>Pre- or perioperative chemo- or radiochemotherapy and subsequent resection is the standard therapy for locally advanced esophageal, gastric, and rectal cancer. A tumor regression grading (TRG; also tumor regression grade) categorizes the extent of the regressive changes after a neoadjuvant treatment. There are several TRG systems for gastrointestinal carcinomas that relate either to the extent of the therapy-induced fibrosis in relation to the residual tumor or the estimated proportion of the residual tumor in the area of the former tumor area. An ideal TRG system shows significant interobserver agreement and offers relevant prognostic information - in most cases a complete or almost complete regression after neoadjuvant therapy is associated with an improved prognosis. In this review, the most commonly used TRG systems for gastrointestinal carcinomas are presented and discussed. In addition, current issues such as the standardization of TRG and the subject of regression in lymph node metastases in the context of a TRG system are discussed.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"51-56"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39628305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Pathology of hepatocellular carcinoma]. [肝细胞癌病理]。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2022-01-04 DOI: 10.1007/s00292-021-01038-0
Thomas Longerich, Peter Schirmacher
{"title":"[Pathology of hepatocellular carcinoma].","authors":"Thomas Longerich,&nbsp;Peter Schirmacher","doi":"10.1007/s00292-021-01038-0","DOIUrl":"https://doi.org/10.1007/s00292-021-01038-0","url":null,"abstract":"<p><p>Hepatocellular carcinoma (HCC) represents the third leading cause of cancer-related mortality worldwide and has a well-defined etiology. It develops in a stepwise process with morphologically defined precursor lesions. Typing of highly differentiated hepatocellular tumors is supported by immunohistological marker panel and the so-called matrix diagnosis. The recent World Health Organization (WHO) classification defined morpho-molecular HCC subtypes showing typical clinical and prognostic characteristics. If HCC subtyping is considered in future clinical studies of advanced HCC, this could help to introduce personalized HCC therapy. Currently, precision oncology is not available for HCC.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"67-78"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39872997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Two new sections: "Molecular Tumor Board" and "Picture of the Month"]. [新增两个板块:“分子肿瘤板”和“月度图片”]。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2022-01-25 DOI: 10.1007/s00292-021-01045-1
Wilfried Roth, Matthias Gaida
{"title":"[Two new sections: \"Molecular Tumor Board\" and \"Picture of the Month\"].","authors":"Wilfried Roth,&nbsp;Matthias Gaida","doi":"10.1007/s00292-021-01045-1","DOIUrl":"https://doi.org/10.1007/s00292-021-01045-1","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitteilungen der IAP. 来自国际原子能机构的消息
4区 医学
Pathologe Pub Date : 2022-02-01 DOI: 10.1007/s00292-021-01043-3
{"title":"Mitteilungen der IAP.","authors":"","doi":"10.1007/s00292-021-01043-3","DOIUrl":"https://doi.org/10.1007/s00292-021-01043-3","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"79-82"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Spring symposium pathology of the gastrointestinal tract]. 【春季会饮胃肠道病理】。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2022-01-25 DOI: 10.1007/s00292-021-01048-y
Heike I Grabsch, Rupert Langer, Michael Vieth
{"title":"[Spring symposium pathology of the gastrointestinal tract].","authors":"Heike I Grabsch,&nbsp;Rupert Langer,&nbsp;Michael Vieth","doi":"10.1007/s00292-021-01048-y","DOIUrl":"https://doi.org/10.1007/s00292-021-01048-y","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"5-7"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dank an die Gutachter*innen von Der Pathologe. 感谢Der Pathologe的专家们。
4区 医学
Pathologe Pub Date : 2022-02-01 DOI: 10.1007/s00292-021-01047-z
{"title":"Dank an die Gutachter*innen von Der Pathologe.","authors":"","doi":"10.1007/s00292-021-01047-z","DOIUrl":"https://doi.org/10.1007/s00292-021-01047-z","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"3-4"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39828927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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