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Mitteilungen des Bundesverbandes Deutscher Pathologen 德国病理学家联邦协会消息
4区 医学
Pathologe Pub Date : 2022-03-01 DOI: 10.1007/s00292-022-01054-8
{"title":"Mitteilungen des Bundesverbandes Deutscher Pathologen","authors":"","doi":"10.1007/s00292-022-01054-8","DOIUrl":"https://doi.org/10.1007/s00292-022-01054-8","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"169-170"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46499254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cytology of body cavity fluids - established methods and new developments]. [体腔液体细胞学-已建立的方法和新进展]。
4区 医学
Pathologe Pub Date : 2022-03-01 Epub Date: 2022-01-07 DOI: 10.1007/s00292-021-01042-4
Marianne Engels
{"title":"[Cytology of body cavity fluids - established methods and new developments].","authors":"Marianne Engels","doi":"10.1007/s00292-021-01042-4","DOIUrl":"https://doi.org/10.1007/s00292-021-01042-4","url":null,"abstract":"<p><strong>Background: </strong>Body cavity fluids are among the most frequently examined samples in cytology. Cytomorphology is supplemented by additive testing. An international system of terminology and classification has been recently presented.</p><p><strong>Objectives: </strong>Cytopreparation and staining techniques as well as some exemplary morphological patterns are presented. \"The International System for Serous Fluid Cytopathology\" (TIS) is briefly presented.</p><p><strong>Materials and methods: </strong>Pleural effusion, pericardial effusion, and ascites: special technical issues, immunocytochemistry, molecular diagnostics, and reporting system issues are discussed.</p><p><strong>Results: </strong>Body cavity fluids are important samples that provide significant information. Additive testing is established for routine use. The form and structure of reports is widely divergent in practical use.</p><p><strong>Discussion: </strong>A reporting system for serous fluid cytopathology that is easily applied and recognized internationally is highly desirable. TIS is a valuable approach to this goal.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 2","pages":"91-98"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39793618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Mesenchymal tumors and tumor-like lesions of the gastrointestinal tract: an overview]. 胃肠道间充质肿瘤和肿瘤样病变:综述。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2021-12-17 DOI: 10.1007/s00292-021-01040-6
Abbas Agaimy
{"title":"[Mesenchymal tumors and tumor-like lesions of the gastrointestinal tract: an overview].","authors":"Abbas Agaimy","doi":"10.1007/s00292-021-01040-6","DOIUrl":"https://doi.org/10.1007/s00292-021-01040-6","url":null,"abstract":"<p><p>Mesenchymal tumors and tumor-like lesions of the gastrointestinal (GI) tract are uncommon. They vary from reactive tumefactive lesions and benign neoplasms to highly aggressive sarcomas. Among them, GI stromal tumors (GISTs) are most common, followed, with less frequency, by smooth muscle and neurogenic tumors. The major challenge resides in correctly identifying GISTs and providing a comprehensive report (including risk assessment and genotyping) that represents the basis for an optimized surgical-oncological treatment and/or adjuvant therapy. On the other hand, the challenge of benign lesions is to find a good name (well understandable and reproducible diagnostic term) that helps avoid diagnostic ambiguity and prognostic uncertainty so that overprognostication and overtreatment can be prevented. Moreover, several recently described genetically defined benign and malignant entities need be correctly diagnosed due to their special \"targeted\" therapeutic options and to further characterize their clinicopathological and biological properties in the future. These recent entities include aggressive epithelioid inflammatory myofibroblastic sarcoma (ALK-RANBP2-driven), malignant gastrointestinal neuroectodermal tumor (EWSR1-ATF1/CREB-related), NTRK-rearranged neoplasms, and, most recently, colorectal NUTM1-rearranged sarcomas. This review highlights the major clinicopathological features of gastrointestinal mesenchymal lesions in light of recent developments.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"31-44"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39734908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Tumor budding in colorectal cancer-Information for clinical use and instructions for practical evaluation]. [结直肠癌的肿瘤萌芽--临床使用信息和实际评估说明]。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2021-11-01 DOI: 10.1007/s00292-021-01016-6
Felix Müller, Alessandro Lugli, Heather Dawson
{"title":"[Tumor budding in colorectal cancer-Information for clinical use and instructions for practical evaluation].","authors":"Felix Müller, Alessandro Lugli, Heather Dawson","doi":"10.1007/s00292-021-01016-6","DOIUrl":"10.1007/s00292-021-01016-6","url":null,"abstract":"<p><strong>Background: </strong>Some patients with high-risk colorectal cancer show a worse prognosis within the same UICC stage. Therefore, the identification of additional risk factors is necessary to find the best treatment for these patients.</p><p><strong>Objective: </strong>In which settings can tumor budding help the clinical decision-making process for treatment planning and how should scoring be performed?</p><p><strong>Material and methods: </strong>Evaluation of current publications on tumor budding with an emphasis on practical grading and potential problems in the determination of tumor budding.</p><p><strong>Results: </strong>Tumor budding is a significant risk factor for worse clinical outcome of colorectal cancer and can influence clinical decision-making in pT1 and stage II colorectal cancer. A scoring method was standardized by the ITBCC 2016 and is feasible in everyday practice. Challenges in assessment can be addressed by increasing awareness of potential problem cases.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"45-50"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39581726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The updated WHO classification of digestive system tumours-gastric adenocarcinoma and dysplasia. 最新的WHO消化系统肿瘤分类-胃腺癌和不典型增生。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2021-11-22 DOI: 10.1007/s00292-021-01023-7
R Kushima
{"title":"The updated WHO classification of digestive system tumours-gastric adenocarcinoma and dysplasia.","authors":"R Kushima","doi":"10.1007/s00292-021-01023-7","DOIUrl":"https://doi.org/10.1007/s00292-021-01023-7","url":null,"abstract":"<p><p>The fifth edition of the World Health Organization (WHO) classification of digestive system tumours was published in 2019. The classification of invasive carcinoma is basically the same as in the fourth edition, but the description of each histological type has been updated, and some rare subtypes such as micropapillary carcinoma, gastric adenocarcinoma of the fundic gland type and undifferentiated carcinoma have been added and explained. Although this classification did not provide specific numerical criteria for the diagnosis of signet-ring cell carcinoma in poorly cohesive carcinoma, an additional study defined signet-ring cell carcinoma as having more than 90% signet-ring cells. The molecular classification of gastric cancer (Epstein-Barr virus-positive type, microsatellite instability type, genomically stable type, chromosomally unstable type) was additionally introduced. Many pages in the present classification have been devoted to precancerous lesions, and this article focuses on foveolar-type adenoma/dysplasia.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"8-15"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39646486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
[Strongyloides stercoralis infection]. [粪类圆线虫感染].
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2022-01-11 DOI: 10.1007/s00292-021-01046-0
Andreas Kreft, Martin S Dennebaum
{"title":"[Strongyloides stercoralis infection].","authors":"Andreas Kreft,&nbsp;Martin S Dennebaum","doi":"10.1007/s00292-021-01046-0","DOIUrl":"https://doi.org/10.1007/s00292-021-01046-0","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"2"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39686607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histologic features of colonic infections. 结肠感染的组织学特征。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2021-11-12 DOI: 10.1007/s00292-021-01015-7
Maria Westerhoff
{"title":"Histologic features of colonic infections.","authors":"Maria Westerhoff","doi":"10.1007/s00292-021-01015-7","DOIUrl":"https://doi.org/10.1007/s00292-021-01015-7","url":null,"abstract":"<p><strong>Background: </strong>The histopathologic diagnosis of infectious colitis remains relevant despite recent advances in microbiologic techniques.</p><p><strong>Objective: </strong>This article aims to describe the histologic features of selected infectious diseases of the colon.</p><p><strong>Materials and methods: </strong>Existing reports on histopathologic and clinical aspects of colonic infectious agents were reviewed.</p><p><strong>Results: </strong>While histology alone may not be as sensitive as current microbiologic methods, tissue identification of infectious agents still plays an important role in patient care. Infectious colitis can have a variety of clinical manifestations, ranging from strongyloidiasis, which can cause a smoldering, subclinical infection for decades, to syphilis, which can clinically mimic cancer or inflammatory bowel disease. Therefore, the histopathologic identification of infection as the cause of a patient's colitis has a considerable impact on treatment decisions. Morphologic overlap can occur between infection and other diseases, however. Moreover, some infections can elicit various tissue responses beyond acute colitis. Immunosuppressed patients may not mount an inflammatory response to pathogens such as cytomegalovirus or adenovirus. Sexually transmitted proctocolitis can cause plasma-cell-rich inflammation. Gastrointestinal histoplasmosis is more likely to cause diffuse histiocyte infiltration rather than the expected granuloma formation. In some cases, ancillary tests are useful, but equivocal results can cause diagnostic dilemmas.</p><p><strong>Conclusion: </strong>Given the range with which colonic infectious disorders can manifest, pathologists should be aware of the typical features of infectious colitis, as well as findings beyond the classic morphologies.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"16-30"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8588779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39703193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Mitteilungen der Österreichischen Gesellschaft für Klinische Pathologie und Molekularpathologie. 来自奥地利临床病理学和分子病理学协会的信
4区 医学
Pathologe Pub Date : 2022-02-01 DOI: 10.1007/s00292-021-01037-1
{"title":"Mitteilungen der Österreichischen Gesellschaft für Klinische Pathologie und Molekularpathologie.","authors":"","doi":"10.1007/s00292-021-01037-1","DOIUrl":"https://doi.org/10.1007/s00292-021-01037-1","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"86-88"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8788401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39963672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The molecular pathology breviary: read depth and coverage in NGS analysis]. [分子病理学简章:阅读NGS分析的深度和覆盖面]。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2021-10-13 DOI: 10.1007/s00292-021-01009-5
Ulrich Lehmann, Albrecht Stenzinger
{"title":"[The molecular pathology breviary: read depth and coverage in NGS analysis].","authors":"Ulrich Lehmann,&nbsp;Albrecht Stenzinger","doi":"10.1007/s00292-021-01009-5","DOIUrl":"https://doi.org/10.1007/s00292-021-01009-5","url":null,"abstract":"","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"65-66"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39513639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Standardized structured reports for gastrointestinal tumors]. 【胃肠肿瘤标准化结构化报告】。
4区 医学
Pathologe Pub Date : 2022-02-01 Epub Date: 2021-10-05 DOI: 10.1007/s00292-021-00986-x
Ekkehard Hewer, Anna Rump, Rupert Langer
{"title":"[Standardized structured reports for gastrointestinal tumors].","authors":"Ekkehard Hewer,&nbsp;Anna Rump,&nbsp;Rupert Langer","doi":"10.1007/s00292-021-00986-x","DOIUrl":"https://doi.org/10.1007/s00292-021-00986-x","url":null,"abstract":"<p><p>Synoptic reporting in pathology as opposed to traditional narrative reporting is defined by a laboratory value-like format and use of standardized checklists. It contributes to completeness and comprehensibility of pathology reports and ultimately patient care. As of today, two major institutions publish synoptic reporting templates, the College of American Pathologists (CAP) and the International Collaboration for Cancer Reporting (ICCR). Synoptic protocols are available for all major cancer types and provide not only a standardized terminology and a checklist for completeness of reports, but also facilitate uniform utilization of diagnostic criteria. Additionally, both CAP and ICCR protocols are accompanied by detailed and up-to-date reference lists and thereby represent a valuable source of information even when synoptic reporting is not used. The benefits and challenges of implementation of synoptic reporting are discussed, in particular with regard to reporting in German.</p>","PeriodicalId":54641,"journal":{"name":"Pathologe","volume":"43 1","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8789623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39488449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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