Postepy Dermatologii I Alergologii最新文献_第9页

Translation and validation of the Polish language version of the Teenagers Quality of Life questionnaire (T-QoL). 波兰语版青少年生活质量问卷（T-QoL）的翻译和验证。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-12-01 Epub Date: 2024-01-08 DOI: 10.5114/ada.2023.133584

Zuzanna Pawlak, Piotr K Krajewski, Ewa Wójcik, Aleksandra Stefaniak, Faraz M Ali, Andrew Y Finlay, Jacek C Szepietowski

{"title":"Translation and validation of the Polish language version of the Teenagers Quality of Life questionnaire (T-QoL).","authors":"Zuzanna Pawlak, Piotr K Krajewski, Ewa Wójcik, Aleksandra Stefaniak, Faraz M Ali, Andrew Y Finlay, Jacek C Szepietowski","doi":"10.5114/ada.2023.133584","DOIUrl":"10.5114/ada.2023.133584","url":null,"abstract":"Introduction: Skin diseases affect patients at any age, but as each period in life is different, tools used to assess quality of life impairment should be adjusted according to the particular age group. Adolescence is a unique time, when young individuals go through many changes, making them especially vulnerable to stress.Aim: Translation and validation of a Polish language version of the Teenagers Quality of Life questionnaire (T-QoL) questionnaire.Material and methods: T-QoL was translated following international guidelines. A group of 34 dermatological patients, aged 12-19 years old, with various skin diseases were given the T-QoL as well as the CDLQI or DLQI to complete. They were also asked to complete the T-QoL questionnaire for the second time after 3-5 days. Statistical analysis of the results was performed.Results: The Polish version of T-QoL is internally consistent (Cronbach α 0.893 for the whole questionnaire). Moreover, it presents very good convergent validity (ICC = 0.864). No statistically significant differences between each question were noticed between the first and second time of completing the form. T-QoL scores correlated significantly with DLQI (p = 0.008, r = 0.636) and CDLQI (p < 0.001, r = 0.777) scores.Conclusions: The Polish version of the T-QoL questionnaire is a reliable instrument with adequate convergent validity, consistency and reproducibility. It can be successfully used to measure quality of life impairment among teenagers.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10809826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139571927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hailey-Hailey disease exacerbated by scabies: the role of dermatoscopy in preventing misdiagnosis. 由疥疮加重的黑利-黑利病:皮肤镜检查在预防误诊中的作用。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-08-01 DOI: 10.5114/ada.2023.130477

Magdalena Żychowska, Marta Kołt-Kamińska, Robert Kijowski, Adam Reich

引用次数: 0

Rowell syndrome. 罗综合症。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-08-01 DOI: 10.5114/ada.2023.130514

Hussah Fahad Abdullah Aldousari, Deemah Aldaihani, Nawaf B S N Al-Mutairi

引用次数: 0

Does molecular scarring in psoriasis exist? A review of the literature. 银屑病分子瘢痕存在吗?文献综述。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-08-01 DOI: 10.5114/ada.2023.129322

Marta Kasprowicz-Furmańczyk, Joanna Narbutt, Adam Borzęcki, Agnieszka Owczarczyk-Saczonek

{"title":"Does molecular scarring in psoriasis exist? A review of the literature.","authors":"Marta Kasprowicz-Furmańczyk, Joanna Narbutt, Adam Borzęcki, Agnieszka Owczarczyk-Saczonek","doi":"10.5114/ada.2023.129322","DOIUrl":"https://doi.org/10.5114/ada.2023.129322","url":null,"abstract":"Plaque psoriasis is a chronic inflammatory dermatosis characterized by a tendency to recur in the same locations after discontinuation of treatment. The implementation of therapy with drugs targeting cytokines like interleukin (IL) 17A (IL-17A) and IL-23 has revolutionized the treatment of psoriasis and enabled the achievement of skin without lesions. However, despite the clinical resolution of psoriatic eruptions, cells that maintain the local memory of the disease remain in the dermis and epidermis, constituting a kind of molecular scar. The cells responsible for maintaining memory in the skin of patients and influencing the rapid relapse of the disease after the triggering factor are primarily tissue resident memory T cells (TRM), but it seems that regulatory T lymphocytes (Treg), dendritic cells (DC), and Langerhans cells (LC) may also play an important role in this process. We reviewed the literature to explain the concept of molecular scarring in psoriasis, and to assess the effect of various therapies on immune memory.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5a/bb/PDIA-40-51052.PMC10485766.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10587692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study effect of MAPA-VIP on control of allergic asthma pathophysiology. MAPA-VIP对变应性哮喘病理生理控制作用的研究。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-08-01 DOI: 10.5114/ada.2023.129458

Weihong Jia, Dongcai Yang

{"title":"Study effect of MAPA-VIP on control of allergic asthma pathophysiology.","authors":"Weihong Jia, Dongcai Yang","doi":"10.5114/ada.2023.129458","DOIUrl":"https://doi.org/10.5114/ada.2023.129458","url":null,"abstract":"Introduction: Asthma is a pulmonary disease and its pathogenesis is involved with immune cells and related signalling pathways. Alpha-alumina is material for therapy applications and mucus adhesion promoting protein is cell-surface protein. Vasoactive intestinal peptide (VIP) exerts immunomodulation. Therefore, the drug delivery system and target binding molecule could be applicable for treatment of asthma.Material and methods: VIP-MapA-α-alumina was administered to asthmatic mice. Then, eosinophil percentage, IgE, IL-4, IL-5, and IL-13 levels, GATA3, and MUC5AC gene expression, ROS and lung histopathology were studied.Results: Eosinophil percentage, IgE, IL-4, IL-5, IL-13, and ROS levels, expression of GATA3 and MUC5AC genes, goblet cell hyperplasia, mucus hyper-production, perivascular and peribronchial inflammation were decreased in VIP and VIP-MapA treated groups and treatment with VIP-MapA has a stronger effect than VIP alone.Conclusions: The delivery system of VIP carrying to the lung with the use of MapA as an adhesion molecule, could easily carry VIP and led to penetration of this component to the mucus and reach bronchial cells and present an effective, strong, and long-acting effect on therapy of asthma.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ca/12/PDIA-40-51079.PMC10485757.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10220453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple segmental piloleiomyoma: unrecognised entity. 多节段性毛羽肌瘤:未被识别的实体。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-08-01 DOI: 10.5114/ada.2023.130493

Grażyna Kamińska-Winciorek, Aleksandra Gładyś, Magdalena Suchorzepka-Simek

引用次数: 0

Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up? 非多发中型先天性黑素细胞痣:切除还是随访?

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-08-01 DOI: 10.5114/ada.2023.128718

Mateusz K Mateuszczyk, Karolina Świerczyńska-Mróz, Iwona Chlebicka, Jacek C Szepietowski

{"title":"Non-multiple medium-sized congenital melanocytic nevi: to excise or to follow up?","authors":"Mateusz K Mateuszczyk, Karolina Świerczyńska-Mróz, Iwona Chlebicka, Jacek C Szepietowski","doi":"10.5114/ada.2023.128718","DOIUrl":"https://doi.org/10.5114/ada.2023.128718","url":null,"abstract":"Introduction: Congenital melanocytic nevi (CMN) are benign lesions composed of clonal proliferations of melanocytes. Although medium-sized CMN are common and generally remain benign throughout a person's lifetime, they may be precursors of melanoma. There is a limited number of studies focused on the risk of melanoma in solitary, medium-sized, congenital melanocytic nevus; therefore, the incidence of malignant transformation and guidelines for treatment are not well established.Aim: Prompted by the limited data, we conducted this study to gather more information about medium-sized CMN, to optimize clinical care. We share our analysis of surgically removed medium-sized CMN.Material and methods: A total of 10 patients with non-multiple, medium-sized, congenital melanocytic nevus were included in this study. Lesions were removed using surgical procedures.Results: In most of the cases the reason for excision of the medium-sized CMN was evolution of the lesion or aesthetic considerations reported by the patients. In 2 cases, due to the large size of the lesions, serial excisions were performed, while other CMN were removed surgically using simple excision technique. Eight of 10 medium-sized CMN were histologically described as benign, and 2 cases of malignant transformations were reported.Conclusions: According to our clinical experience and knowledge, we recommend managing patients on an individual basis, taking into consideration multiple clinical attributes. In our opinion, long-lasting observation is the management of choice, and if there is need of surgery, we recommend total simple or staged excision depending on nevus size.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3e/5f/PDIA-40-50865.PMC10485756.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10587690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant inflammatory linear verrucous epidermal nevus: difficulties in the management. 巨大炎性线状表皮疣状痣:治疗困难。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-08-01 DOI: 10.5114/ada.2023.128684

Beata Bień, Ewa Wójcik, Iwona Chlebicka, Jacek C Szepietowski

引用次数: 0

Successful treatment of a child's lupus erythematosus tumidus with antimalarials. 用抗疟药物成功治疗儿童红斑狼疮一例。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-08-01 DOI: 10.5114/ada.2023.130475

Hubert Arasiewicz, Grażyna Kamińska-Winciorek, Michał Dec, Lilianna Leśniak-Jakubiec

引用次数: 0

Hidradenitis suppurativa - biologic therapy and other available treatment options. 化脓性汗腺炎-生物治疗和其他可用的治疗选择。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2023-08-01 DOI: 10.5114/ada.2021.112075

Katarzyna Lipa, Natalia Zając, Grzegorz Witkowski, Piotr Ciechanowicz, Kacper Wiszniewski, Elżbieta Szymańska, Irena Walecka

{"title":"Hidradenitis suppurativa - biologic therapy and other available treatment options.","authors":"Katarzyna Lipa, Natalia Zając, Grzegorz Witkowski, Piotr Ciechanowicz, Kacper Wiszniewski, Elżbieta Szymańska, Irena Walecka","doi":"10.5114/ada.2021.112075","DOIUrl":"https://doi.org/10.5114/ada.2021.112075","url":null,"abstract":"Hidradenitis suppurativa (HS) is a chronic recurrent inflammatory skin disease which is characterized by painful, recurrent nodules and abscesses. The overall prevalence of HS is estimated to be 11 per 100 000 individuals in the United States and 4% of the world's population. Women are three times more affected than men, especially patients between 18 and 29 years. Similarly to acne vulgaris, HS is primarily associated with follicular occlusion, which results from a number of biological processes, including follicular epithelial hyperplasia and hyperkeratinization. There are numerous available treatment options for cutaneous lesions in the course of HS. A combination of conservative therapy and appropriate surgical treatment conducted by an experienced surgeon ensures the best possible clinical outcomes. Presently, biologic therapy is the most effective pharmacological treatment in patients with a moderate-to-severe course of the disease. Numerous ongoing clinical trials provide hope for greater availability of new biologic therapy methods.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/31/PDIA-40-45948.PMC10485753.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10220463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1