Postepy Dermatologii I Alergologii最新文献_第7页

Comparative assessment of alcaftadine and olopatadine for allergic conjunctivitis: a meta-analysis. 阿咖啡因和奥洛他定治疗过敏性结膜炎的比较评价：一项荟萃分析。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-12-01 Epub Date: 2024-11-14 DOI: 10.5114/ada.2024.144166

Xiaojuan Fu, Peijie Xu, Di Lu

{"title":"Comparative assessment of alcaftadine and olopatadine for allergic conjunctivitis: a meta-analysis.","authors":"Xiaojuan Fu, Peijie Xu, Di Lu","doi":"10.5114/ada.2024.144166","DOIUrl":"10.5114/ada.2024.144166","url":null,"abstract":"Introduction: It is unclear to compare the efficacy of alcaftadine versus olopatadine for patients with allergic conjunctivitis, and this meta-analysis aims to perform the comparative assessment of their efficacy for allergic conjunctivitis.Methods: We systematically searched PubMed, Embase, Web of Science, EBSCO, and Cochrane library databases, and included randomized controlled trials (RCTs) comparing alcaftadine with olopatadine for allergic conjunctivitis. The random-effect model was used for the significant heterogeneity, and otherwise the fixed-effect model was used.Results: Twelve RCTs and 1064 patients with allergic conjunctivitis were included in this meta-analysis. In comparison with olopatadine intervention, alcaftadine intervention demonstrated a comparable ocular symptom score on 3 days (MD = -0.06; 95% CI = -0.19 to 0.07; p = 0.35), but was able to significantly decrease the ocular symptom score on 7 days (MD = -0.09; 95% CI = -0.16 to -0.01; p = 0.03), ocular symptom score on 14 days (MD = -0.25; 95% CI = -0.37 to -0.12; p < 0.0001) and conjunctival hyperaemia score on 14 days (MD = -0.04; 95% CI = -0.05 to -0.03; p < 0.00001). These two groups had similar incidence of adverse events (OR = 0.61; 95% CI = 0.34 to 1.09; p = 0.10).Conclusions: Alcaftadine had better capability to treat allergic conjunctivitis compared to olopatadine.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"41 6","pages":"560-565"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Available questionnaires do not cover important aspects of quality of life of patients with cutaneous T-cell lymphoma: evaluation of the quality of life of Polish patients with cutaneous T-cell lymphoma. 现有的问卷没有涵盖皮肤t细胞淋巴瘤患者生活质量的重要方面：波兰皮肤t细胞淋巴瘤患者生活质量的评估。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-11-24 eCollection Date: 2025-04-01 DOI: 10.5114/ada.2024.145289

Agnieszka Giza, Małgorzata Sokołowska-Wojdyło, Hanna Ciepłuch, Berenika Olszewska, Roman J Nowicki, Karol Kołkowski

{"title":"Available questionnaires do not cover important aspects of quality of life of patients with cutaneous T-cell lymphoma: evaluation of the quality of life of Polish patients with cutaneous T-cell lymphoma.","authors":"Agnieszka Giza, Małgorzata Sokołowska-Wojdyło, Hanna Ciepłuch, Berenika Olszewska, Roman J Nowicki, Karol Kołkowski","doi":"10.5114/ada.2024.145289","DOIUrl":"10.5114/ada.2024.145289","url":null,"abstract":"Introduction: Cutaneous T-cell lymphoma (CTCL) has a significant impact on patients' quality of life (QoL). Most studies have measured QoL using validated questionnaires that are not specific to patients with CTCL. Furthermore, clinician-perceived QoL in CTCL patients has never been measured before.Aim: The quantitative and qualitative evaluation of QoL of the Polish CTCL patients and doctors and checking the impact of the disease on their daily functioning.Material and methods: Structured anonymous questionnaires were administered to Polish patients diagnosed with CTCL and their physicians. The questionnaire was designed on the basis of interviews with two physicians, experts in the field, and 2 patients. Patients completed the questionnaire and the Skindex-29 survey in person.Results: Our patients have been moderately affected in the physical domain and significantly affected in the emotional and functional domains according to Skindex-29, whereas according to the results of our questionnaire, the most affected domains are the physical and emotional domains. The biggest inconvenience for patients is commuting to another city and time spent on visits and tests. We are the first to report that 57% of patients try to distract themselves from thinking about the diagnosis, 55% hope for a normal life and 64% miss previous lifestyle and/or opportunities.Conclusions: Polish physicians underestimated the impact of the disease on insomnia, sleep disturbance and patient independence. Although the Skindex-29 is a widely used and validated tool, it may not fully capture all aspects of QoL in patients with CTCL.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"42 2","pages":"156-163"},"PeriodicalIF":1.4,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Apoptosis and PTX3 in lichen planus. 扁平地衣细胞凋亡与PTX3的关系。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-11-21 eCollection Date: 2025-04-01 DOI: 10.5114/ada.2024.145205

Ibrahim H Yavuz, Göknur Özaydın Yavuz, Nazlı Caf, Mustafa Tümtürk, Harbiye Dilek Canat, Mehmet Onur Gökalp

{"title":"Apoptosis and PTX3 in lichen planus.","authors":"Ibrahim H Yavuz, Göknur Özaydın Yavuz, Nazlı Caf, Mustafa Tümtürk, Harbiye Dilek Canat, Mehmet Onur Gökalp","doi":"10.5114/ada.2024.145205","DOIUrl":"10.5114/ada.2024.145205","url":null,"abstract":"Introduction: Lichen planus (LP) is considered a T cell-mediated autoimmune disease although its aetiology remains unknown. Cytotoxic T cells play a central role in the pathogenesis of LP and these cells are known to significantly induce apoptosis in basal keratinocytes.Aim: To correlate pentraxin 3 (PTX3) with apoptosis in basal cell keratinocytes in LP and to determine whether it is a marker in this disease.Material and methods: Inclusion criteria were as follows: (i) providing written consent for participation, (ii) presence of typical clinical findings (livid-red, violaceous, flat-topped polygonal papules and plaques, fern appearance in the oral mucosa, flexural involvement, and Wickham's striae) and (iii) histopathological confirmation of LP.Results: A total of 60 participants, 30 patients and 30 controls, were included in the study. No difference was found between groups in terms of age and gender. There was a significant difference in PTX3 levels between groups. As to patients with LP, 21 (70%) patients had skin involvement only, 2 (6.7%) patients had mucosal involvement only, and 7 (23.3%) patients had both skin and mucosal involvement of LP.Conclusions: PTX3 may be associated with apoptosis in LP. Although there are no data on the usability of PTX3 as a specific marker of LP, the present study aimed to demonstrate its usability as a marker of active LP.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"42 2","pages":"171-174"},"PeriodicalIF":1.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitivity of serum galactomannan antigen in the diagnosis of invasive aspergillosis in patients with obstructive pulmonary diseases (asthma and chronic obstructive pulmonary diseases). 血清半乳甘露聚糖抗原对阻塞性肺疾病（哮喘和慢性阻塞性肺疾病）患者侵袭性曲霉病诊断的敏感性

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-11-21 eCollection Date: 2025-04-01 DOI: 10.5114/ada.2024.145208

Xiaoyan Hu, Xiaoling Hu, Yangdan Zhu, Huijia Hu, Zhuoping Wang

{"title":"Sensitivity of serum galactomannan antigen in the diagnosis of invasive aspergillosis in patients with obstructive pulmonary diseases (asthma and chronic obstructive pulmonary diseases).","authors":"Xiaoyan Hu, Xiaoling Hu, Yangdan Zhu, Huijia Hu, Zhuoping Wang","doi":"10.5114/ada.2024.145208","DOIUrl":"10.5114/ada.2024.145208","url":null,"abstract":"Introduction: Adverse clinical outcomes often result from the concomitant presence of invasive pulmonary aspergillosis (IPA) in patients with obstructive pulmonary diseases (asthma and chronic obstructive pulmonary diseases (COPD)).Aim: This work was developed to assess the risk factors (RFs) for patients with concurrent IPA and the diagnostic sensitivity of existing detection methods.Material and methods: This was a case control study on patients with acute exacerbation of obstructive pulmonary diseases (OPD) hospitalized from January 2022 to December 2023; patients were categorized into an IPA group (n = 39) and a non-IPA group (n = 37) based on test results. Information about smoking history, diabetes history, usage of broad-spectrum antibiotics (BSAs) and corticosteroids, and serum albumin levels were collected. After univariate analysis, a multivariate logistic regression (MLR) analysis was performed. Additionally, the diagnostic sensitivity and specificity of GM antigen, IgG, and IgM detection were compared.Results: Prolonged use of BSAs (≥ 2 weeks) and corticosteroids (≥ 3 weeks), along with low albumin levels emerged as independent RFs for concurrent IPA. The sensitivity of GM antigen detection (64.1%) was the highest among the three methods, with specificity slightly lower than IgG detection (75.68%, 81.08%), yet still not reaching the ideal level.Conclusions: Risk assessment for asthma and COPD patients with concurrent IPA should encompass an evaluation of prolonged antibiotic and steroid use, along with a comprehensive consideration of nutritional and immune status. Current IPA detection methods should be evaluated in conjunction with clinical conditions to enhance diagnostic accuracy.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"42 2","pages":"183-189"},"PeriodicalIF":1.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Giant basal cell carcinoma located in the temporal region: delay of the patient's visit because of COVID-19 pandemic. 位于颞区的巨大基底细胞癌：因COVID-19大流行而延误患者就诊。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-11-18 eCollection Date: 2025-04-01 DOI: 10.5114/ada.2024.144485

Amelia Głowaczewska, Iwona Chlebicka, Zuzanna Pawlak, Jacek C Szepietowski

引用次数: 0

Classical and biological treatments in mycosis fungoides/Sézary syndrome. New horizons in oncodermatology. 蕈样真菌病/ ssamzary综合征的经典和生物治疗。肿瘤皮肤病学的新视野。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-11-14 eCollection Date: 2025-04-01 DOI: 10.5114/ada.2024.144999

Hanna R Cisoń, Rafał K Białynicki-Birula

引用次数: 0

Challenging diagnosis of the spectrum of reactive granulomatous dermatitis: two case reports and literature review. 反应性肉芽肿性皮炎频谱的挑战性诊断：两例报告和文献复习。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-10-03 eCollection Date: 2025-04-01 DOI: 10.5114/ada.2024.143435

Barbara Olszewska, Adriana Polańska, Monika Bowszyc-Dmochowska, Ryszard Żaba, Aleksandra Dańczak-Pazdrowska

引用次数: 0

Illness acceptance among young adults with acne: a cross-sectional study. 患有痤疮的年轻人对疾病的接受程度：一项横断面研究。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-10-01 Epub Date: 2024-08-10 DOI: 10.5114/ada.2024.142580

Beata Bień, Piotr Krajewski, Jacek Cezary Szepietowski

{"title":"Illness acceptance among young adults with acne: a cross-sectional study.","authors":"Beata Bień, Piotr Krajewski, Jacek Cezary Szepietowski","doi":"10.5114/ada.2024.142580","DOIUrl":"10.5114/ada.2024.142580","url":null,"abstract":"Introduction: The level of acceptance of acne can have a substantial impact on improving patients' mood and quality of life.Aim: To investigate the level of acne vulgaris acceptance among young patients and its correlation with disease severity, quality of life, and feelings of stigmatization.Material and methods: The study was conducted on 213 young individuals diagnosed with acne. A variety of questionnaires were employed to measure the psychological aspects of the condition, including illness acceptance, quality of life, and feeling of stigmatization.Results: Based on the Global Evaluation Acne (GEA) scale, 45% of participants had mild acne, 31.7% had minimal acne, and 23.3% had moderate acne. The Acceptance of Illness Scale (AIS) scores ranged from 13 to 40, with a mean of 37.0 ±5.2 points. Males had higher illness acceptance (mean score: 37.7 vs. 36.5 points; p = 0.027). Most participants (87.6%) had high illness acceptance. The greatest challenge was adjusting to disease limitations. A significant negative correlation was found between acne severity and illness acceptance (r = -0.277; p < 0.001), between AIS scores and both QoL impairment (measured by the Dermatology Life Quality Index (DLQI) and the Cardiff Acne Disability Index (CADI)) (r = -0.499 and r = -0.621, respectively; p < 0.001 for both) as well as between AIS scores and the 6-Item Stigmatization Scale (6-ISS) (r = -0.621, p < 0.001).Conclusions: The level of acne acceptance depends on gender and the severity of acne lesions. Based on the study results, we hypothesize that an intervention aimed at increasing the level of disease acceptance could improve patients' psychological well-being and ability to cope with the condition.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"41 5","pages":"530-535"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary cutaneous aggressive epidermotropic CD8+ cytotoxic T-cell lymphoma with aberrant CD56 expression: a rare case report. 原发性皮肤侵袭性表皮向CD8+细胞毒性T细胞淋巴瘤伴CD56异常表达：一例罕见病例报告。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-10-01 Epub Date: 2024-10-24 DOI: 10.5114/ada.2024.144399

Shuaihantian Luo, Yingdan Chen, Guiying Zhang

引用次数: 0

Changes and correlation of serum levels of interleukins 33, 15, 4, and interferon γ in children with bronchial asthma at different periods. 支气管哮喘患儿不同时期血清白细胞介素 33、15、4 和干扰素 γ 水平的变化及相关性。

IF 1.4 4区医学

Postepy Dermatologii I Alergologii Pub Date : 2024-10-01 Epub Date: 2024-09-06 DOI: 10.5114/ada.2024.143542

Liangliang Geng, Ruixue Xiao, Ke Chang

{"title":"Changes and correlation of serum levels of interleukins 33, 15, 4, and interferon γ in children with bronchial asthma at different periods.","authors":"Liangliang Geng, Ruixue Xiao, Ke Chang","doi":"10.5114/ada.2024.143542","DOIUrl":"10.5114/ada.2024.143542","url":null,"abstract":"Aim: This work investigated the difference of serum cytokine levels in children with bronchial asthma (BA) in acute attack and clinical remission and the relationship between them.Material and methods: A hundred children with BA were included and enrolled into an acute attack group (AA group) and a clinical remission group (CR group) according to their medical history and clinical characteristics, with 50 children in each group. Then, another 50 healthy children in the same hospital for physical examination were randomly selected as controls.Results: Interleukin (IL) 4 (IL-4) and interferon-γ (IFN-γ) levels in the AA group were significantly higher than those in controls (p < 0.05), but the IL-4 and IFN-γ levels in the clinical remission phase group were not remarkably different from those in controls (p > 0.05). The IL-15 level in the AA group was much higher than that in children with BA in the clinical remission stage and controls, and the IL-15 level in the CR control was higher than that in controls (p < 0.05). IL-4 level was positively linked with INF-γ level (r = 15.621, p = 0.002) and IL-15 level (r = 9.581, p = 0.008). IL-15, IL-4, and IFN-γ were related to the incidence of BA of children and played a role in the exacerbation of respiratory inflammation during acute attacks. IL-4 was associated with IL-15 and INF-γ, and there was a synergistic relationship in promoting inflammation of BA.","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"41 5","pages":"473-478"},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11589639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0