Research in Nursing & Health最新文献

{"title":"Factors Influencing Shoulder Joint Function in Patients With Type 2 Diabetes Mellitus Following Arthroscopic Rotator Cuff Repair: A Mixed-Methods Study.","authors":"Ming Zhang, Huaixia Zhang, Jun Zheng","doi":"10.1002/nur.22429","DOIUrl":"10.1002/nur.22429","url":null,"abstract":"<p><p>To identify the influencing factors of shoulder joint function after Arthroscopic Rotator Cuff Repair (ARCR) in patients with Type 2 Diabetes Mellitus (T2DM). A sequential explanatory mixed-methods design was conducted. Participants were recruited from the Northern Jiangsu People's Hospital from January 2023 to May 2023. Quantitative data were collected using the Constant-Murley Shoulder Joint Function Score, the General Self-Efficacy Scale, and the Perceived Social Support Scale. A total of 134 patients were recruited (120 participants for questionnaire survey, 14 participants for interview). Spearman's correlations were performed to initially identify the influencing factors of shoulder joint function. Qualitative data were collected through face-to-face interviews with 14 patients. To understand patients' experiences during the process of shoulder joint recovery, interpretative phenomenological analysis was employed. The triangulation was conducted using convergence coding matrix. Three themes and seven sub-themes were identified, including capability (postoperative pain management, self-management of T2DM), opportunity (medical supports, perceived social and family supports, demands of economic supports), and motivation (sense of benefits, psychological motivation). The recovery of shoulder joint function in patients with T2DM following ARCR is influenced by factors related to capability, opportunity, and motivation. Healthcare providers should enhance the timing and content of educational interventions and provide intensive psychological support to facilitate successful behavior change and optimize shoulder joint recovery in this patient population. The findings of this study can inform the development of an optimized care model for patients with T2DM following ARCR, empowering them to take control of their condition. Considering the long-term challenges of rehabilitation, which present physical and psychological difficulties for patients, it is essential to design interventions strategies that address physiological decline and pain management.</p>","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":"110-120"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of a Behavior Intervention Based on the Recurrence Risk Perception and Behavioral Decision Model for Ischemic Stroke Patients: A Randomized Controlled Trial.","authors":"Jie Zhang, Zhenxiang Zhang, Beilei Lin, Hu Jiang, Yongxia Mei, Xin Li, Ling Ma","doi":"10.1002/nur.22445","DOIUrl":"10.1002/nur.22445","url":null,"abstract":"<p><p>Behavioral management is essential to preventing recurrence after stroke, but its adherence is limited worldwide. We aimed to assess the impact of the behavior intervention based on the Recurrence risk perception and Behavioral decision Model for ischemic stroke patients' health behavior. This study was a single-blind, randomized, controlled trial with a 3-month follow-up. The outcome measures were the perception of the risk of stroke recurrence, behavioral decision, and health behavior. A total of seventy participants were randomized to the intervention group (n = 35) or control group (n = 35). The former received a twelve-week theory-based intervention in addition to the routine education, while the control group received only the routine education. The generalized estimating equations results indicated that the intervention group had significantly greater improvements in perception of the risk of stroke recurrence compared to the control group at all T1 (B = 0.13, 95% CI: 0.03 to 0.23), T2 (B = 0.18, 95% CI: 0.07 to 0.28), and T3 (B = 0.16, 95% CI: 0.07 to 0.25) after adjusting for stroke frequency. Statistically significant improvements were found in behavioral decision for the intervention group compared with the control group at T2 (B = 0.25, 95% CI: 0.09 to 0.41) and T3 (B = 0.26, 95% CI: 0.10 to 0.43). Results also showed a significantly higher increase in health behavior at T1 (B = 0.29, 95% CI: 0.09 to 0.48) and T2 (B = 0.22, 95% CI: 0.04 to 0.40). The intervention can improve the perception of the risk of stroke recurrence, behavioral decision, and health behavior in ischemic stroke patients. IMPLICATIONS: This study provides a reference point for promoting healthy behaviors in patients with ischemic stroke. A recurrence risk perception and behavioral decision model-based intervention was deemed to be feasible and useful in practice. PATIENT OR PUBLIC CONTRIBUTION: Patients and their caregivers agreed to participate in the study and shared their experiences of participating in research with us.</p>","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":"246-256"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Judgment Model-Based Critical Reflection Program for Newly Graduated Nurses: A Nonrandomized Controlled Trial.","authors":"Ae Ran Kim, Jeong Hee Hong, Kyeongsug Kim, Yuna Kim, Jung Min Lee, Heejin Lee, Ji Hyun Yoon, Mi Soon Kim","doi":"10.1002/nur.22444","DOIUrl":"10.1002/nur.22444","url":null,"abstract":"<p><p>This study evaluated the effects of a critical reflection program utilizing the Lasater Clinical Judgment Rubric (LCJR) reflective questions based on the Clinical Judgment Model (CJM) on newly graduated nurses' clinical judgment skills. A total of 153 newly graduated nurses scheduled for on-site training in a ward nursing unit were divided into a control group (receiving only the usual on-site training with preceptorship) and an experimental group (receiving the developed program with the same on-site training with preceptorship as the control group). Data were collected at baseline, 6 weeks, and 3 months after the intervention. A comparison of the scores of the two groups at each measurement time point revealed that the experimental group showed significantly higher scores than the control group in clinical judgment (z = 3.25, p = 0.003) and stage of noticing (z = 2.78, p = 0.015) at 6 weeks postintervention. Clinical reasoning competence (experimental χ² = 24.57, p < 0.001; control χ² = 41.12, p < 0.001) and clinical judgment (experimental χ² = 12.74, p = 0.002; control χ² = 10.54, p = 0.005) significantly improved scores across the three time points in both groups. The change in scores in the responding stage of clinical judgment from preintervention to 6 weeks postintervention showed a significant difference between the two groups (z = -2.44, p = 0.045). A critical reflection program based on the CJM can help newly graduated nurses enhance their clinical judgment over a short period during the early stages of clinical adaptation.</p>","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":"234-245"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of the Chinese Version of Aberdeen Varicose Veins Questionnaire (AVVQ) in Patients With Varicose Veins of Lower Extremity: A Cross-Sectional Study.","authors":"Chen Wang, Wenjing Yang, Xiaojun Shen, Jing Xu, Xia Wang, Chao Ji, Siwen Hu","doi":"10.1002/nur.22431","DOIUrl":"10.1002/nur.22431","url":null,"abstract":"<p><p>Varicose veins in the lower extremities significantly impairs patients' quality of life, highlighting the importance of targeted quality of life assessments for specific diseases. The Aberdeen Varicose Vein Questionnaire (AVVQ) was specifically designed to assess the impact of lower extremity varicose veins on quality of life. This study comprised two phases: in the first phase, the AVVQ was translated and culturally adapted, and the second phase was an evaluation of the psychometric characteristics of the Chinese version of AVVQ in 328 patients with varicose veins of lower extremities. Confirmatory factor analysis revealed that the Chinese AVVQ comprises 13 items distributed across four dimensions, accounting for a total variance of 61.74%, with a Cronbach's α of 0.745 and a content validity index of 0.908. Furthermore, there was a negative correlation between the AVVQ scores and the SF-36. In addition, the difference in AVVQ scores by CEAP classification was statistically significant. These findings affirmed the Chinese version of the AVVQ as both reliable and valid, making it a valid tool for evaluating the quality of life in Chinese patients with varicose veins and applicable across various international contexts and diverse patient populations.</p>","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":"100-109"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nurse Practitioner Care Environments and Provider Shortages Among Patients With Multiple Chronic Conditions.","authors":"Amy McMenamin, Eleanor Turi, Jianfang Liu, Grant Martsolf, Lusine Poghosyan","doi":"10.1002/nur.22446","DOIUrl":"10.1002/nur.22446","url":null,"abstract":"<p><p>In health professional shortage areas (HPSAs), primary care providers face challenges due to high workloads and limited resources, impacting their ability to provide comprehensive care to patients with multiple chronic conditions (MCCs). In addition, patients in HPSA compared to non-HPSA settings experience poorer outcomes. Nurse practitioners (NPs) play a crucial role in meeting MCC patients' needs, but some work in unfavorable care environments (e.g., lacking teamwork, support, and autonomy) that hinder their capacity to manage complex chronic diseases. This study examines the effect of NP care environments on the relationship between HPSA status and hospitalizations or emergency department (ED) visits among patients with MCCs. We conducted a secondary analysis of merged Medicare claims, NP survey data, and Health Resources and Services Administration data. Our sample included 779 practices with 394,424 Medicare beneficiaries aged 65+ who had at least two of 15 chronic conditions. We used logistic regression to evaluate the impact of HPSA status and the NP care environment on ED visits or hospitalizations. NP care environments moderate the association between HPSA status and hospitalization (AOR 1.165, 95% CI [1.037-1.309], p = 0.010) but not ED use. Improved care environments are associated with lower odds of hospitalization in non-HPSAs (β = -0.148, 95% CI [-0.225, -0.072], p = 0.0001), while in HPSAs, improved care environments have no effect on hospitalization odds (β = 0.0047, 95% CI [-0.086, 0.096], p = 0.920). Addressing provider shortages in HPSAs may allow an improved NP care environment to produce maximal benefits for patients.</p>","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":"271-280"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and Reliability of Patient Activation Measure (PAM13-I) Italian Version Among Patient Undergoing Elective Surgery.","authors":"Maria Provenzano, Nicola Cillara, Mauro Podda, Cesar Ivan Aviles Gonzalez, Enrico Cicalò, Pietro Fransvea, Gaetano Poillucci, Antonello Deserra, Luigi Ricciardelli, Maria Jiménez-Herrera","doi":"10.1002/nur.22447","DOIUrl":"10.1002/nur.22447","url":null,"abstract":"<p><p>The patient activation measure (PAM), a recognized measure of how active patients are in their care, is one of the most extensively used, widely translated, and tested instruments worldwide in measuring patient activation. This study aimed to assess the psychometric properties and construct validity of the Italian version of the 13-item Patient Activation Measure (PAM13-I) among patients undergoing elective laparoscopic cholecystectomy. A multicenter study was conducted across 111 surgical units in Italy. This study involved the preoperative administration of the PAM questionnaire to 4532 patients. The psychometric properties of the PAM were evaluated using Rasch analysis. The PAM13-I demonstrated good internal consistency (Cronbach's α = 0.95) and reliability indices. While fit statistics were acceptable, ceiling effects were observed. No significant differential item functioning was found. However, issues with targeting and local response dependency were identified. The Italian PAM-13 showed promising psychometric properties among surgical patients, indicating its potential utility in assessing patient activation. However, concerns regarding ceiling effects and targeting suggest the need for further refinement and validation in surgical populations.</p>","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":"281-293"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chinese Translation and Measurement of the Heart Failure Needs Assessment Questionnaire in Mainland China.","authors":"Qian Mei, Xiaoli Yang, Jingwen Zhang, Xiancheng Xiang, Xinyang Liu, Li Cheng","doi":"10.1002/nur.22436","DOIUrl":"10.1002/nur.22436","url":null,"abstract":"<p><p>The management of heart failure in patients presents a significant challenge to global public health, marked by an increase in unaddressed needs due to the extended deterioration of health. It is crucial to conduct comprehensive assessments of patients with heart failure, thereby providing personalized care. The purpose of this study was to translate, adapt, and validate the Needs Assessment Questionnaire for people with heart failure in Mainland China and to evaluate its reliability and validity within a population of people with heart failure. A cohort of 246 individuals diagnosed with heart failure was recruited from two medical facilities in China during the period from January 2023 to June 2023. The scale was translated into Chinese using the forward post-translation technique, followed by an evaluation of its reliability and validity. Descriptive statistics, content validity assessment, and Confirmatory Factor Analysis were utilized for validation. Internal consistency, split-half reliability, and test-retest reliability assessments were conducted to assess overall reliability. The Chinese version of the Heart Failure Needs Assessment Questionnaire consists of 4 dimensions and 30 items. The Cronbach α coefficient of the overall scale was 0.90. In the validation factor analysis, the model fit results were χ²/df = 2.259, CFI = 0.933, IFI = 0.933, TLI = 0.927, RMSEA = 0.072, all of which fell within acceptable ranges. The HFNAQ demonstrates strong reliability and validity in assessing the unmet needs of patients with heart failure.</p>","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":"159-167"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Workplace Violence and Health Status of Female Nurses: A Cross-Sectional Study.","authors":"Eman Alhalal","doi":"10.1002/nur.22434","DOIUrl":"10.1002/nur.22434","url":null,"abstract":"&lt;p&gt;&lt;p&gt;As a female-dominant profession, nurses are at risk of workplace violence. However, the health outcomes of workplace violence among female nurses have been mostly studied in isolation from their history of lifetime violence experiences. Although social and organizational factors shape workplace violence, our understanding of its effects on female nurses' health is limited in different cultural contexts. This study examined how workplace violence affects the physical and mental health and the frequency of medication intake and sick leave of nurses employed in the Saudi healthcare system while controlling for the effect of lifetime violence experiences. A cross-sectional study was conducted with 340 female nurses working in tertiary hospitals in Saudi Arabia. Among the female nurses, 67.6% had experienced at least one act of workplace violence during the last 12 months. The highest level of workplace violence was recorded in nurses employed in psychiatric units. After controlling for the effect of child abuse and partner violence, workplace violence is associated with female nurses' physical health ( &lt;math&gt; &lt;semantics&gt; &lt;mrow&gt;&lt;mrow&gt;&lt;mi&gt;β&lt;/mi&gt;&lt;/mrow&gt; &lt;/mrow&gt; &lt;annotation&gt;&lt;math altimg=\"urn:x-wiley:01606891:media:nur22434:nur22434-math-0001\" wiley:location=\"equation/nur22434-math-0001.png\" display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"&gt;&lt;mrow&gt;&lt;mrow&gt;&lt;mi mathvariant=\"normal\"&gt;unicode{x003B2}&lt;/mi&gt;&lt;/mrow&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt;  = 0.335, t(336) = 6.73, p &lt; 0.001), mental health ( &lt;math&gt; &lt;semantics&gt; &lt;mrow&gt;&lt;mrow&gt;&lt;mi&gt;β&lt;/mi&gt;&lt;/mrow&gt; &lt;/mrow&gt; &lt;annotation&gt;&lt;math altimg=\"urn:x-wiley:01606891:media:nur22434:nur22434-math-0002\" wiley:location=\"equation/nur22434-math-0002.png\" display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"&gt;&lt;mrow&gt;&lt;mrow&gt;&lt;mi mathvariant=\"normal\"&gt;unicode{x003B2}&lt;/mi&gt;&lt;/mrow&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt;  = 0.224, t(336) = 4.09, p &lt; 0.001), medication intake ( &lt;math&gt; &lt;semantics&gt; &lt;mrow&gt;&lt;mrow&gt;&lt;mi&gt;β&lt;/mi&gt;&lt;/mrow&gt; &lt;/mrow&gt; &lt;annotation&gt;&lt;math altimg=\"urn:x-wiley:01606891:media:nur22434:nur22434-math-0003\" wiley:location=\"equation/nur22434-math-0003.png\" display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"&gt;&lt;mrow&gt;&lt;mrow&gt;&lt;mi mathvariant=\"normal\"&gt;unicode{x003B2}&lt;/mi&gt;&lt;/mrow&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt;  = 0.240, t(336) = 4.45, p &lt; 0.001), and frequency of sick leave days ( &lt;math&gt; &lt;semantics&gt; &lt;mrow&gt;&lt;mrow&gt;&lt;mi&gt;β&lt;/mi&gt;&lt;/mrow&gt; &lt;/mrow&gt; &lt;annotation&gt;&lt;math altimg=\"urn:x-wiley:01606891:media:nur22434:nur22434-math-0004\" wiley:location=\"equation/nur22434-math-0004.png\" display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"&gt;&lt;mrow&gt;&lt;mrow&gt;&lt;mi mathvariant=\"normal\"&gt;unicode{x003B2}&lt;/mi&gt;&lt;/mrow&gt;&lt;/mrow&gt;&lt;/math&gt;&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt;  = 0.206, t(336) = 3.82, p &lt; 0.001). The results indicate a need for a zero-tolerance policy against workplace violence and multidimensional strategies to address the issue. Additionally, gender and multi-component health interventions for female nurses wh","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":"121-132"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Link Your Large Health Data Sets to the Area Deprivation Index, the ezADI Way.","authors":"Sunnie Reagan, Drew Prescott, Xueyuan Cao, Tyra Girdwood, Keesha Roach, Ansley Grimes Stanfill","doi":"10.1002/nur.22461","DOIUrl":"https://doi.org/10.1002/nur.22461","url":null,"abstract":"<p><p>Increasing attention has been paid to investigations on how social determinants of health (SDOH; e.g., income, employment, education, housing, etc.) impact health outcomes. However, these variables are often not collected in routine clinical practice. As a consequence, researchers may attempt to link retrospective medical records to those datasets that can provide additional SDOH information, such as the Area Deprivation Index (ADI). However, time-consuming geographic calculations can deter these analyses. To reduce this burden, the ezADI R package performs batched geocoder mapping on inputted addresses, constructs Federal Information Processing Series (FIPS) codes, and then merges these data with ADI scores. The applicability and feasibility of this ezADI tool was tested on a sample of patients with sickle cell disease (SCD). Individuals with SCD are at risk for developing serious comorbidities; disadvantageous SDOH may increase this risk, in turn leading to higher rates of hospital utilization and longer lengths of stay on admission. In this sample of 1,105 individuals with SCD in Tennessee (53.8% female, 97.5% African American), higher ADI scores (i.e., more neighborhood disadvantage) were significantly associated with increased hospital utilization (rho = 0.093, p = 0.002) and longer lengths of stay (rho = 0.069, p = 0.021). These areas could be targeted with neighborhood-level interventions and other resources to improve SDOH. This study provides proof of concept that the ezADI tool simplifies geocoding calculations to allow researchers to link datasets with the ADI and assess associations between SDOH factors and health outcomes.</p>","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frailty and the Survival of Patients With Endometrial Cancer: A Meta-Analysis.","authors":"Shanshan Jia, Min Zhang","doi":"10.1002/nur.22456","DOIUrl":"https://doi.org/10.1002/nur.22456","url":null,"abstract":"<p><p>The aim of this study is to investigate the association between frailty and overall survival (OS) and progression-free survival (PFS) in women with endometrial cancer (EC). Frailty is increasingly recognized as a significant predictor of outcomes in cancer patients, yet its impact on survival among EC patients remains unclear. This study is a systematic review and meta-analysis. PubMed, Embase, and Web of Science from database inception to September 28, 2024 were searched for cohort studies evaluating frailty in relation to survival in EC patients. Inclusion criteria focused on studies reporting hazard ratios (HRs) for OS or PFS, comparing frail versus nonfrail patients. A random-effects model was applied. Eight cohort studies involving 486,138 women reported the outcome of OS, and 4 of them involving 378 women also reported the outcome of PFS. Frailty was associated with poor OS (HR: 1.78, 95% confidence interval [CI]: 1.56-2.03, p < 0.001) without significant heterogeneity (I² = 0%). Sensitivity analyses confirmed the stability of this association. Subgroup analyses according to the mean age of the patients, tools for evaluating frailty, follow-up duration, and study quality score showed consistent results (p for subgroup difference: 0.35-0.98). Four studies indicated a significant association between frailty and worse PFS (HR: 1.91, 95% CI: 1.24-2.95, p = 0.003), also with no heterogeneity (I² = 0%). The results of the study conclude that frailty is associated with poor survival in EC. Although these findings should be validated in large prospective cohort studies, this meta-analysis highlights the possible role of frailty assessment in risk stratification and prognostic prediction of patients with EC. No patient or public contribution.</p>","PeriodicalId":54492,"journal":{"name":"Research in Nursing & Health","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}