Revista Espanola De Medicina Nuclear最新文献

{"title":"Biopsia de ganglio centinela en pacientes con cáncer de mama y cirugía mamaria previa","authors":"I. Blanco ,&nbsp;D. Díaz ,&nbsp;C. Moriyón ,&nbsp;L. Santamaría ,&nbsp;M.A. Díez ,&nbsp;M.T. López ,&nbsp;H. Padín ,&nbsp;F. Cantero ,&nbsp;S. Artime ,&nbsp;F. Domínguez ,&nbsp;F.J. Aira ,&nbsp;R. Álvarez-Obregón","doi":"10.1016/j.remn.2011.03.005","DOIUrl":"10.1016/j.remn.2011.03.005","url":null,"abstract":"<div><h3>Aim</h3><p>The aim of this study was to establish the efficacy and safety of sentinel lymph node biopsy for lymph node staging in patients with breast cancer and prior breast surgery, considering its extension, localization and time since the previous surgical procedure.</p></div><div><h3>Material and methods</h3><p>A sentinel lymph node biopsy was performed in 38 patients with early breast cancer and previous breast surgery: recent excisional biopsy in 22 patients (Group I), previous lumpectomy or mammoplasty in 16, including one case of cancer treated with breast-conserving surgery (tumor recurrence). Lymphoscintigraphy was performed after periareolar injection, also sometimes adding an injection near to the surgical scar. After removing the sentinel node, axillary lymph node dissection was performed when the lymph node was positive (and not localized).</p></div><div><h3>Results</h3><p>The efficacy of the scintigraphic localization of the sentinel node was 92.1% of the patients, with 15.8% of extra-axillary drainages. Axillary intraoperative detection was 81.6%. The identification rate after recent excisional biopsy or previous surgery was similar (81.8 vs 81.2%). However, extra-axillary sentinel nodes were more frequent in Group II (9.1 vs 25%). Having a localization of previous surgical procedures in upper outer quadrant caused drainages outside of the axilla more frequently (27.2 vs 11.1%). Axillary detection rate was similar to other quadrants (81.8 vs 81.5%). The rate of breast cancer-related events was 5.2% (2/38), without axillary recurrences (mean follow-up: 3 years).</p></div><div><h3>Conclusion</h3><p>Sentinel lymph node biopsy in patients with previous but not extensive breast surgery is safe. Extra-axillary drainages are more common when the previous surgical area was wide, especially in the upper-outer quadrant.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 223-228"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2011.03.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29846181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inyección subareolar: potencial causa de falso negativo en la biopsia selectiva de ganglio centinela en cáncer de mama","authors":"M.E. Rioja Martín ,&nbsp;G. Ortega Pérez ,&nbsp;L.J. Cabañas Montero ,&nbsp;V. Muñoz-Madero ,&nbsp;L. Cabañas Navarro","doi":"10.1016/j.remn.2010.07.008","DOIUrl":"10.1016/j.remn.2010.07.008","url":null,"abstract":"<div><p>Sentinel node biopsy has become the standard practice in lymph node staging in breast cancer in early stages. However, uncertainty remains regarding the best method of radiotracer/dye injection. Currently, the subareolar injection is being widely used because of its technical simplicity and higher rates of SN location versus the so-called deep techniques (peritumoral, intratumoral) that require greater specialization and greater use of resources in the non-palpable lesions.</p><p>We present a case of a discrepancy between the two techniques that could have caused a false negative.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 251-253"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.07.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29772293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiencia con rosiglitazona como tratamiento rediferenciador en un caso de carcinoma papilar de tiroides con metástasis pulmonares y ausencia de captación de radioyodo","authors":"M. Elola ,&nbsp;A. Yoldi ,&nbsp;J.I. Emparanza ,&nbsp;T. Matteucci ,&nbsp;I. Bilbao ,&nbsp;M. Goena","doi":"10.1016/j.remn.2010.08.005","DOIUrl":"10.1016/j.remn.2010.08.005","url":null,"abstract":"<div><p>Treatment with radioiodine (RDI) has been shown to be an effective option in patients with differentiated thyroid cancer with recurrent or metastatic disease. However, in spite of having elevated levels of thyroglobulin in blood, in some of these patients, the whole body scan does not detect radioiodine uptake due to loss of differentiation of the neoplastic cells, thus leading to loss of efficacy of the treatment. That is why drugs with potential differentiating properties, like rosiglitazone or retinoids, are being studied. The aim of these drugs is to improve RDI uptake by the tumor cells. In this work, we have described the case of a patient in whom uptake of RDI by the pulmonary metastases, with subsequent decrease of their size, was achieved after treatment with rosiglitazone (8<!--> <!-->mg/day for 2 months) as redifferentation therapy.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 241-243"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.08.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29682428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tomografía por emisión de positrones con 18F-fluorodesoxi-glucosa en un caso de cáncer de vejiga con metástasis cutánea única","authors":"J. Contreras Gutiérrez,&nbsp;L. Frutos Esteban,&nbsp;J.L. Navarro Fernández,&nbsp;M.A. Claver Valderas","doi":"10.1016/j.remn.2010.11.003","DOIUrl":"10.1016/j.remn.2010.11.003","url":null,"abstract":"","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 254-255"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.11.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29775439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agenda","authors":"","doi":"10.1016/j.remn.2011.05.004","DOIUrl":"https://doi.org/10.1016/j.remn.2011.05.004","url":null,"abstract":"","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Page 263"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2011.05.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136408250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocolo de cirugía de rescate guiada por PET/TAC. Resultados con técnica ROLL y sonda PET","authors":"J.R. García,&nbsp;M. Fraile,&nbsp;M. Soler,&nbsp;J. Bechini,&nbsp;J.R. Ayuso,&nbsp;F. Lomeña","doi":"10.1016/j.remn.2011.02.011","DOIUrl":"10.1016/j.remn.2011.02.011","url":null,"abstract":"<div><h3>Objective</h3><p>To assess the value of intraoperatory radioguided probe detection to guide surgical resection of malignant lesions previously detected by ¹⁸F-FDG PET-CT.</p></div><div><h3>Material</h3><p>Twelve consecutive patients with suspected tumor recurrence detected by ¹⁸F-FDG PET-CT considered resectable were enrolled in the study. Ultrasound guided fine needle aspiration (FNA) before surgery was performed in 6 patients and CT guided biopsy was performed in 1 patient. In 5 patients with accessible lesions, a radioguided occult lesion localization (ROLL) technique was performed after injection of ^99mTc-colloid (1.7-2.4 mCi) inside the lesion under ultrasound or CT guidance, pre-operatively. Radioguided surgical detection was then carried out 19-24<!--> <!-->hours afterwards using the gamma probe. In 7 patients with non-accessible needle lesions or multiple lesions, 9.5-10.5 mCi of ¹⁸F-FDG were injected 3-5<!--> <!-->hours before radioguided surgery using a PET-dedicated probe (Gamma locator DXI-GF&amp;E).</p></div><div><h3>Results</h3><p>ROLL technique: All lesions injected with nanocolloid were resected (6 lesions in 5 patients, 1 patient with 2 lesions), and recurrence was histologically confirmed. PET probe: Fourteen out of 16 hypermetabolic lesions detected on the PET-CT were resected. One cervical and one mediastinal lymph node in different patients could not be excised. Histological recurrence was confirmed in 12 out of 14 lesions. In one patient, the 2 lymph nodes excised were inflammatory.</p></div><div><h3>Conclusions</h3><p>¹⁸F-FDG PET-CT can be key in deciding surgical approach and appropriate radioguided protocol. When lesions are solitary and easily accessible, ROLL technique seems the method of choice. PET probe is more adequate for less accessible lesions.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 217-222"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2011.02.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29835263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thigh splints. Gammagrafía ósea","authors":"A. García Brunet ,&nbsp;C. Guitart Pardellans ,&nbsp;A. Lira Aguilar ,&nbsp;Ll. Bernà Roqueta ,&nbsp;J.C. Martín Miramón ,&nbsp;A. Rodríguez Revuelto","doi":"10.1016/j.remn.2011.02.005","DOIUrl":"10.1016/j.remn.2011.02.005","url":null,"abstract":"","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Page 262"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2011.02.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29835265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foco pulmonar facticio con 18F-FDG: posible error en la interpretación de la PET-CT","authors":"M.C. Redal Peña ,&nbsp;F.J. Pena Pardo ,&nbsp;J. Muñoz Iglesias ,&nbsp;A. Crespo-Jara ,&nbsp;J. Rebollo ,&nbsp;A. Brugarolas Masllorens","doi":"10.1016/j.remn.2010.07.007","DOIUrl":"10.1016/j.remn.2010.07.007","url":null,"abstract":"<div><p>¹⁸F-FDG PET-CT has become an essential tool in oncology patient management. The normal distribution of the FDG and the possible artifacts (pitfalls), including those from CT-based attenuation correction, have already been described in several reviews.</p><p>However, only a few cases of FDG focal lung uptake have been reported recently.</p><p>We present two cases of oncology patients during a routine follow-up with this type of pitfall, without morphological correlation in the CT scan. We repeated the study in one of them, which made it possible to verify normalization of the hyperuptake, orienting us towards a possible pitfall.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 248-250"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.07.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29772291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avances en una aventura de dos años","authors":"F. Pons","doi":"10.1016/j.remn.2011.05.005","DOIUrl":"10.1016/j.remn.2011.05.005","url":null,"abstract":"","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 209-210"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2011.05.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29945977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infarto de miocardio silente diagnosticado por SPECT de perfusión miocárdica en mujer joven con lupus eritematoso sistémico","authors":"A. Bogdan Ciobotaru ,&nbsp;M.C. Pombo Pasín ,&nbsp;M. Garrido Pumar ,&nbsp;J. Díaz Garel ,&nbsp;V. Pubul Núñez ,&nbsp;A. Ruibal Morell","doi":"10.1016/j.remn.2010.08.007","DOIUrl":"10.1016/j.remn.2010.08.007","url":null,"abstract":"<div><p>Premature atherosclerosis and its consequent heart disease play a crucial role in patients with systemic lupus erythematosus, even in premenopausal women. It is one of the leading causes of death in long evolution lupus.</p><p>We present the case of a 42-year-old premenopausal woman, smoker, with a history of hypertension, cholecystectomy and lupus for 23 years, treated with NSAID, steroids and antimalarial drugs. The patient consulted due to chest pain on moderate efforts. Due to the suspicion of ischemic heart disease, a cardiology study was initiated, performing a myocardial perfusion SPECT. This revealed an intense and extensive anterolateral perfusion defect, with very light reperfusion in rest images, consistent with the diagnosis of acute infarction in the apical region and ischemia in the territory of the left anterior descending artery, which was confirmed later by cardiac catheterization.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 244-247"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.08.007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29684078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}