Revista Espanola De Medicina Nuclear最新文献

{"title":"El SPECT con 201Talio en la detección de recidiva del carcinoma de laringe","authors":"M. Negre Busó ,&nbsp;J. Lorente Guerrero ,&nbsp;A. Rubió Rodríguez ,&nbsp;M. García López ,&nbsp;M. González Doñate ,&nbsp;M. Boronat de Ferrater ,&nbsp;J. Castell Conesa","doi":"10.1016/j.remn.2010.12.008","DOIUrl":"10.1016/j.remn.2010.12.008","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the diagnostic yield of ²⁰¹Thallium SPECT in the detection of local and/or regional lymph node dissemination of pharyngolaryngeal carcinoma.</p></div><div><h3>Material and methods</h3><p>29 patients who had been diagnosed with pharyngolaryngeal carcinoma were studied (mean age: 60.9 years). These patients had been treated by surgery, chemotherapy and radiotherapy. At between 3 to 6 month after finishing the treatment, all of them underwent a planar and SPECT study at one hour after the administration of 148 MBq of ²⁰¹Thallium. Uptake was scored on four grades: from 0 (no uptake) to 3 (very intense uptake). The presence or non-presence of lymph nodes with uptake was also evaluated. All the results on the scintigraphy were correlated with long term clinical and radiological follow-up (mean: 2.5 years). The studies were classified as positive for recurrence when the uptake was 2-3 and/or with presence of lymph nodes with uptake.</p></div><div><h3>Results</h3><p>We obtained 9 true positive, 14 true negative, 3 false positive and 3 false negative results. Sensitivity was 75%, specificity was 82.4%, positive predictive value was 75% and negative predictive value was 82.4%. Two out of three false positives corresponded to the surgical bed uptake and one was attributed to the laterocervical lymph nodes. The three false negatives had grade 1 uptakes, two of them corresponding to pulmonary metastasis without evidence of local recurrence.</p></div><div><h3>Conclusions</h3><p>The use of ²⁰¹Thallium SPECT in the prognostic evaluation in patients with a treated laryngeal carcinoma shows very acceptable results in the detection of local recurrence and/or regional lymph node dissemination.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 236-240"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.12.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30164987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hallazgo accidental de un adenoma túbulo-velloso de recto mediante 18F-FDG PET en un paciente diagnosticado de linfoma linfocítico","authors":"J. Banzo ,&nbsp;M.A. Ubieto ,&nbsp;P. Giraldo ,&nbsp;C. Yus ,&nbsp;A. Santapau ,&nbsp;A. Parra","doi":"10.1016/j.remn.2010.10.014","DOIUrl":"10.1016/j.remn.2010.10.014","url":null,"abstract":"","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 256-257"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.10.014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29772289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilidad de la PET/TAC en la estadificación mediastínica del cáncer de pulmón de células no pequeñas en estadio III (N2)","authors":"R. Sánchez Sánchez ,&nbsp;A. Rodríguez Fernández ,&nbsp;M. Gómez Río ,&nbsp;A. Alkurdi Martínez ,&nbsp;V.E. Castellón Rubio ,&nbsp;C. Ramos Font ,&nbsp;A. Sánchez-Palencia Ramos ,&nbsp;J.R. Delgado Pérez ,&nbsp;J.M. Llamas Elvira","doi":"10.1016/j.remn.2011.02.010","DOIUrl":"10.1016/j.remn.2011.02.010","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate the accuracy of integrated positron emission tomography with ¹⁸F-fluoro-2-deoxy-D-glucose (FDG) and computed tomography (PET/CT) in mediastinal lymph node staging in patients with potentially operable (N2) non-small cell lung cancer (NSCLC) and to ascertain the role of invasive staging in verifying positron emission tomography (PET)/computed tomography (CT) results.</p></div><div><h3>Material and methods</h3><p>A retrospective study of consecutive patients with pathologically-proven NSCLC and N2 staging by enhanced CT was performed. A PET/CT scan was performed for all the patients. Lymph node staging was pathologically confirmed when it was possible or by consensus in the Thoracic Cancer Committee. Sensitivity, specificity, negative predictive value and positive predictive value of PET/CT in N2 cases were determined.</p></div><div><h3>Results</h3><p>A total of 34 patients with N2 by CT were evaluated. PET/CT showed N2 in 30 patients. Discrepancies were found in four patients, two patients were classified as N1 in PET/CT and two patients as N0. Lymph node staging was pathologically confirmed in 20 patients. No false positives were found in PET/CT study. Sensitivity was 94.7%, specificity and positive predictive values were 100% and negative predictive value was 50%.</p></div><div><h3>Conclusions</h3><p>Our data show that integrated PET/CT provides high sensitivity and positive predictive value in mediastinal nodal staging of NSCLC patients. Therefore, in patients with potentially resectable lung cancer, neoadjuvant chemotherapy candidate, mediastinoscopy could be reserved for restaging after induction therapy.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 211-216"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2011.02.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29835620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concordancia interobservador en el análisis visual y semicuantitativo de las imágenes SPECT 123I-FP-CIT en el diagnóstico del síndrome parkinsoniano","authors":"M. Suárez-Piñera ,&nbsp;M.L. Prat ,&nbsp;A. Mestre-Fusco ,&nbsp;J. Fuertes ,&nbsp;S. Mojal ,&nbsp;E. Balaguer","doi":"10.1016/j.remn.2011.02.009","DOIUrl":"10.1016/j.remn.2011.02.009","url":null,"abstract":"<div><h3>Aims</h3><p>Using ¹²³I-FP-CIT SPECT images makes it possible to identify presynaptic deterioration of the dopaminergic pathway by studying the dopamine transporter (DAT). A correct analysis of the SPECT images contributes to an adequate interpretation and diagnosis of movement disorders. Aims: <em>1.</em> To compare visual and semiquantitative analysis of ¹²³I-FP-CIT SPECT images in patients with movement disorders. <em>2.</em> To evaluate interobserver agreement in visual and semiquantitative analysis. <em>3.</em> To obtain a cut-off in the semiquantitative analysis to discriminate primary Parkinsonism Syndrome (PS) from non-primary PS.</p></div><div><h3>Methods</h3><p>A ¹²³I-FP-CIT SPECT was performed in 32 patients with movement disorders suggestive of primary PS. Visual and semiquantitative images analyses were performed independently by two nuclear medicine physicians. Visual analysis was based on the visual interpretation. Semiquantitative analysis was calculated as specific uptake (caudate, putamen and striatum) versus non-specific uptake (occipital). Sensitivity, specificity, PPV, and NPV were calculated. Data were compared using ANOVA test followed by Bonferroni post-hoc test. Interobserver agreement of the visual and semiquantitative analysis was assessed by intraclass correlation coefficient and Kappa statistics, respectively. ROC curve was generated with semiquantitative data.</p></div><div><h3>Results</h3><p>Visual analysis showed 86% sensitivity and 100-88% specificity for the differential diagnosis of primary PS from non-primary PS. Semiquantitative analysis showed a gradual hypouptake proportional to the disease severity obtained in the visual analysis. Semiquantitative analysis did not provide any additional information to the visual analysis. Intraclass correlation coefficient and Kappa statistics showed 0.92 and 0.80 values, respectively. The Cut-off value to differentiate primary PS from non-primary PS was 1.9 on the putamen index.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 4","pages":"Pages 229-235"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2011.02.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29843616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epitrochlear and axillary lymph node visualization on FDG-PET/CT imaging in a patient with rheumatoid arthritis","authors":"P. Ozcan Kara ,&nbsp;B. Kaya ,&nbsp;G. Kara Gedik ,&nbsp;O. Sari","doi":"10.1016/j.remn.2010.04.010","DOIUrl":"10.1016/j.remn.2010.04.010","url":null,"abstract":"<div><p>An 38 year-old female with oral tongue cancer was referred for FDG-PET/CT scan for evaluating axillary lymph nodes and restaging malignancy. Bilateral uptake of axillary and epitrochlear lymph nodes were observed on PET/CT imaging. The uptake pattern was unexpected for the patient with this malignancy and she had a history of rheumatoid arthritis. Additionally, the wrists were included in the field of view and showed elevated FDG uptake. In this case report, we report benign axillary and epitrochlear tracer uptake on FDG-PET/CT scan in a patient with a history of rheumatoid arthritis.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 3","pages":"Pages 168-170"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.04.010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29072353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual extraosseous tumoral accumulation of 99mTc-MDP in non-Hodgkin's lymphoma in two cases","authors":"E. Ceylan Gunay ,&nbsp;A. Erdogan ,&nbsp;D. Apaydin","doi":"10.1016/j.remn.2010.04.012","DOIUrl":"10.1016/j.remn.2010.04.012","url":null,"abstract":"<div><p>The authors describe a rare pattern of soft tissue uptake observed in a ^99mTc-MDP bone scintigraphy of two patients with the diagnosis of non-Hodgkin's lymphoma. Both patients had abdominal masses and bone scintigraphy revealed unusual ^99mTc-MDP uptake in the abdominal region. The possible mechanisms of soft tissue uptake of bone seeking agents are discussed.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 3","pages":"Pages 162-164"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.04.012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29081092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone and peritoneal metastasis of breast carcinoma: findings on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography","authors":"P. Ozcan Kara ,&nbsp;T. Kara ,&nbsp;G. Kara Gedik ,&nbsp;O. Sari","doi":"10.1016/j.remn.2010.07.005","DOIUrl":"10.1016/j.remn.2010.07.005","url":null,"abstract":"","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 3","pages":"Pages 180-181"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.07.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29684075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Falso negativo de la gammagrafía con 99mTc-sestamibi en un carcinoma paratiroideo con tumores pardos asociados. Aportaciones de la PET/TAC-18F-FDG","authors":"A. Santiago Chinchilla,&nbsp;C. Ramos Font,&nbsp;M.A. Muros de Fuentes,&nbsp;M. Navarro-Pelayo Láinez,&nbsp;H. Palacios Gerona,&nbsp;M. Moreno Caballero,&nbsp;J.M. Llamas Elvira","doi":"10.1016/j.remn.2010.08.006","DOIUrl":"10.1016/j.remn.2010.08.006","url":null,"abstract":"<div><p>Parathyroid carcinoma (PTC) is a rare malignant disease that is usually hyperfunctioning, which produces an excess of parathyroid hormone. Hyperparathyroidism causes bone metabolism disorders, as osteopenia and sometimes brown tumors. Brown tumors are benign but locally aggressive bone lesions, whose differential diagnosis with metastases or other primary malignancies may be complicated. ^99mTc-Sestamibi scan is the usual procedure for the detection of parathyroid pathology, with a sensitivity of 85–100% and specificity close to 100% in parathyroid adenomas, it having similar percentages in the detection of PTC. We present the case of a patient diagnosed of a malignant hyperparathyroidism associated with bone lesions in which the ^99mTc-Sestamibi scan showed a false negative result in the detection of parathyroid condition. However, ¹⁸F-FDG-PET/CT detected the PTC and helped in the differential diagnosis of associated bone lesions, which were finally confirmed as brown tumors.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 3","pages":"Pages 174-179"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.08.006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29691169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Captación de I-131 en un quiste renal: un resultado falso positivo","authors":"M. Molina,&nbsp;C. Calvo,&nbsp;T. Cambil,&nbsp;P.A. de la Riva,&nbsp;A. de Bonilla,&nbsp;J. Castro","doi":"10.1016/j.remn.2010.07.004","DOIUrl":"10.1016/j.remn.2010.07.004","url":null,"abstract":"<div><p>We present the case of a 60-year old male with a follicular pattern of multifocal invasive papillary thyroid carcinoma who had undergone total thyroidectomy. During post-surgical follow-up with I-131 scan, a I-131 deposit was observed in the upper left hemiabdomen. Due to suspicion that it could be a metastasis, an ultrasound and CT scan were performed, with the subsequent diagnosis of a left simple serous renal cyst. Once confirmed, drainage was performed under ultrasound control, obtaining I-131 in the analysis of its content.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 3","pages":"Pages 165-167"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.07.004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29718614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Los protocolos de tratamiento y seguimiento del carcinoma diferenciado de tiroides: resultados de un cuestionario enviado a las Unidades de Terapia Metabólica españolas","authors":"M.A. Muros ,&nbsp;J. Arbizu ,&nbsp;M.D. Abós ,&nbsp;M. Mitjavilla ,&nbsp;E. Caballero-Calabuig ,&nbsp;J.A. Vallejo","doi":"10.1016/j.remn.2010.12.005","DOIUrl":"10.1016/j.remn.2010.12.005","url":null,"abstract":"<div><h3>Objective</h3><p>To know the treatment and follow-up protocols of differentiated thyroid carcinoma patients in Spanish Metabolic Therapy Units, the clinical variability between them and the adaptation to the consensus guidelines.</p></div><div><h3>Materials and methods</h3><p>Analysis of the results obtained from the questionnaire submitted by E-mail to the Spanish Society of Nuclear Medicine (SEMNIM) members on the treatment and follow-up of differentiated thyroid carcinoma patients. A descriptive study was made of the qualitative variables (frequency, percentage) and quantitative variables (mean, standard deviation).</p></div><div><h3>Results</h3><p>Twenty Radiometabolic Therapy Units responded to the questionnaire. In spite of the varied origin of the patients, the Units receive sufficient clinical information and have specialized surgeons. There is variability in the surgical protocols and indication for ablation in patients with intermediate and low risk of recurrence. The Units agree on the use of ¹³¹I doses for ablation and therapy, but show great variability regarding the preparation protocols (previous ¹³¹I-whole body scan or other imaging techniques, ¹³¹I-whole body scan dose, diet and radioiodine contrast prohibition, total dose per patient). Nuclear Medicine physicians perceive radioiodine adverse effects and prevention methods are used. The post-ablation follow-up protocol differs between Units.</p></div><div><h3>Conclusions</h3><p>Treatment and follow-up protocols of differentiated thyroid carcinoma patients in the Spanish Radiometabolic Therapy Units show variability in aspects such as surgery and ablation indications, patient preparation for radioiodine therapy and follow-up. Our clinical practice differs in several aspects from the recent consensus guideline recommendations.</p></div>","PeriodicalId":54464,"journal":{"name":"Revista Espanola De Medicina Nuclear","volume":"30 3","pages":"Pages 147-155"},"PeriodicalIF":0.0,"publicationDate":"2011-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.remn.2010.12.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29770754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}