Zeitschrift fur Medizinische Physik最新文献

{"title":"Objective assessment of accommodation with an accommodative intraocular lens: Development of methodology and case report","authors":"Timo Eppig,&nbsp;Violetta Müller,&nbsp;Manuel Seer,&nbsp;Alisa Bölke,&nbsp;Arthur Meßner,&nbsp;Michiel C. Rombach,&nbsp;Eckhard Becker,&nbsp;Jens Schrecker","doi":"10.1016/j.zemedi.2026.03.005","DOIUrl":"10.1016/j.zemedi.2026.03.005","url":null,"abstract":"<div><div><strong>Purpose:</strong> To determine the objectively measurable amplitude of accommodation after implantation of an accommodating intraocular lens (IOL).</div></div><div><h3>Methods:</h3><div>We used an open field autorefractor based on near infrared retinoscopy (PowerRef3, Plusoptix GmbH, Nuremberg, Germany) to determine the change in refraction, pupil diameter and gaze with decreasing distance of the visual stimulus. We compared the signal curves between a young healthy, a presbyopic and a pseudophakic patient as well as three patients implanted with the accommodative IOL Lumina (AMIPLANT GmbH, Schnaittach, Germany).</div></div><div><h3>Results:</h3><div>The refraction, pupil, and gaze curves exhibit the behavior that are expected from theory. The accommodative IOL shows similar curves as the young phakic person, showing that there is a dynamic change in refraction. This is supported by the three-year follow-up data of a patient providing an uncorrected binocular far VA of 1.0 and near visual acuity of 0.8.</div></div><div><h3>Conclusion:</h3><div>The PowerRef3 is capable of measuring the accommodative amplitude of an accommodative IOL. The Lumina shows a accommodative amplitude of up to 2 D and excellent far and near vision in a patient three years after implantation.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 179-188"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147439081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A low-cost, easy-to-implement optical add-on to convert a retinal OCT into a ultra-high-resolution corneal OCT","authors":"Fritz Stange,&nbsp;Sebastian Bohn,&nbsp;Alois Gottschlich,&nbsp;Tobias Korn,&nbsp;Oliver Stachs,&nbsp;Karsten Sperlich","doi":"10.1016/j.zemedi.2025.09.004","DOIUrl":"10.1016/j.zemedi.2025.09.004","url":null,"abstract":"<div><h3>Purpose</h3><div>Commercial anterior segment optical coherence tomography (OCT) systems typically offer sufficient axial resolution to distinguish corneal layers. However, their lateral resolution (∼15–20 µm) is limited, restricting the visualization of fine microstructural features, relevant for noninvasive diagnosis of corneal pathologies. We present a low-cost, easy-to-implement optical add-on that substantially improves the lateral resolution of a standard retinal OCT system, enabling high-fidelity corneal imaging.</div></div><div><h3>Methods</h3><div>Custom-designed optical modules were developed for the standard objective lens of an investigational retinal OCT device. The system design, incorporating a single achromatic lens, was optimized through optical simulations to achieve a higher numerical aperture and reduced focal length. The lateral resolution was evaluated both theoretically, via point spread function, and experimentally using a 1951 United States Air Force (USAF) resolution target. A compact prototype, presented here, was tested on a commercial SPECTRALIS OCT2, compared with the commercial Anterior Segment Module (both Heidelberg Engineering GmbH, Heidelberg, Germany), and tested in vivo on two human subjects, including one with suspected epithelial basement membrane dystrophy (EBMD).</div></div><div><h3>Results</h3><div>The prototype achieved a lateral resolution of 3.1<!--> <!-->µm in the experiment, closely matching the results of the optical simulation. This resolution is markedly better than the 15.6<!--> <!-->µm achieved with the commercial corneal OCT, albeit at a cost of a reduced field of view (2.62<!--> <!-->mm vs. 8.29<!--> <!-->mm). In vivo imaging confirmed enhanced visualization of epithelial microstructures in both healthy and pathological corneas, despite a reduced depth of focus resulting from the higher numerical aperture.</div></div><div><h3>Conclusion</h3><div>The proposed add-on enabled ultra-high-resolution corneal imaging on a standard SPECTRALIS OCT2 platform without the need for major hardware modifications, such as an increased reference arm or dispersion compensation. This low-cost, easy-to-implement approach offers diagnostic value for early detection and longitudinal monitoring of subtle corneal irregularities, particularly in conditions such as EBMD, where a high lateral resolution is critical for clinical decision-making.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 151-156"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the corneal epithelium on the corneal power using 3D raytracing with OCT data","authors":"Achim Langenbucher,&nbsp;Nóra Szentmáry,&nbsp;Alan Cayless,&nbsp;Peter Hoffmann,&nbsp;Jascha Wendelstein","doi":"10.1016/j.zemedi.2025.01.002","DOIUrl":"10.1016/j.zemedi.2025.01.002","url":null,"abstract":"<div><h3>Purpose</h3><div>To study the effects of corneal imaging and focusing using a raytracing simulation with 2 and 3 surface corneal models based on customized surface representations of corneal tomography data .</div></div><div><h3>Methods</h3><div>Raytracing simulation using surface data for the epithelium (S1), stroma (S2) and endothelium (S3) extracted from MS-39 anterior segment tomographer CSV export files. Customized surface representations were derived using Gaussian Process Predictors, and rays traced through the cornea and a 3.5 mm aperture stop located 3.66 mm behind the corneal apex. 4 clinical examples were evaluated: A) after hyperopic LASIK, B) after myopic LASIK, C) keratoconus, and D) after PRK with postoperatively developed Salzmann nodules.</div></div><div><h3>Results</h3><div>The raytracing based bundle focus and wavefront focus distances of the 2 surface (S1 and S3) and 3 surface cornea models (S1, S2 and S3) were comparable, whereas the paraxial focus derived from a 1 surface cornea (S1), 2 (S1 and S3) or 3 surface cornea (S1, S2 and S3) using floating best fit sphere representations for S1, S1 and S3 showed systematically lower / higher focal distance with B) / C) indicating an overestimation / underestimation of corneal power with paraxial calculations.</div></div><div><h3>Conclusions</h3><div>The clinical examples in this study exhibited only minor differences between the mono- and dual layer cornea models. We recommend verification in a larger clinical study. Three surface corneal raytracing models could be of clinical relevance in intraocular lens calculations and LASIK ablation nomograms, offering potential improvements over paraxial calculations especially in cases with surface irregularities.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 157-168"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The coordinate systems in the Hess screen test and the Harms tangent screen test for ocular motility analysis of strabismus: their metrics and relationship","authors":"Theo Oltrup,&nbsp;Marvin Bende,&nbsp;Thomas Bende,&nbsp;Martin A Leitritz,&nbsp;Karl Ulrich Bartz-Schmidt","doi":"10.1016/j.zemedi.2026.01.006","DOIUrl":"10.1016/j.zemedi.2026.01.006","url":null,"abstract":"<div><div>In the diagnosis of strabismus due to paralysis of the eye muscles, the Hess screen test and the Harms tangent screen test are used to measure the misalignment of the eyes in different gaze directions (motility analysis). Both examination methods use different procedures to define the gaze direction and coordinate systems. Coordinate systems with scales in angular degrees are used to determine the direction of gaze and simplify reading the squint angle in the event of a misalignment (horizontal and vertical deviation). In the measurement results, however, their numerical values differ due to the different angle definitions of the direction of gaze in the Hess and Harms tests. In this paper, the angle definitions are clearly described, the coordinate systems are mathematically derived from them, their metrics are formally analysed and compared with the surface theory according to Carl Friedrich Gauss, and their transformation relationship is specified and visualised. The surface theory is used to justify the finding that a measured misalignment of the eye leads to the same motility disorder with the same spatial orientation of the direction of gaze, regardless of the choice of angle. The coordinate systems according to Harms and Hess are therefore mathematically equivalent. However, assessment of the paretic eye muscle(s) and the subsequent therapeutic measures are based on the numerical values of the squint angle measurement. Therefore, knowledge of the test used and its angle definition is important. The procedure for determining the gaze direction determines the choice of coordinate system in the test according to Harms and Hess to avoid systematic measurement deviations.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 189-196"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical optics in medical physics: from photons to quantitative insight","authors":"Achim Langenbucher,&nbsp;Sibylle Scholtz","doi":"10.1016/j.zemedi.2026.03.006","DOIUrl":"10.1016/j.zemedi.2026.03.006","url":null,"abstract":"","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 132-133"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147461498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of nozzle configurations on radiobiological effects in carbon ion radiation therapy estimated using GATE/Geant4","authors":"Hermann Fuchs,&nbsp;Alessio Parisi,&nbsp;Keith M. Furutani,&nbsp;Dietmar Georg,&nbsp;Chris J. Beltran","doi":"10.1016/j.zemedi.2025.04.004","DOIUrl":"10.1016/j.zemedi.2025.04.004","url":null,"abstract":"<div><h3>Background</h3><div>Carbon Ion Radiation Therapy (CIRT) has been used in Europe and in Asia for several decades. The first treatment facility in America is now under construction at Mayo Clinic Florida (MCF) in Jacksonville. CIRT is known to have a variable relative biological effectiveness (RBE) which depends on the microdosimetric spectra and consequently the kinetic energy spectra.</div></div><div><h3>Purpose</h3><div>CIRT centers from different vendors exist around the world with different accelerators, delivery, and nozzle designs. Although nominally they provide comparable energies and beam qualities, this study investigates how the different nozzle designs might affect radiation quality and the consequent RBE.</div></div><div><h3>Methods</h3><div>The impact of three nozzle designs, the upcoming MCF (Jacksonville, USA), MedAustron Ion Therapy Center (Wiener Neustadt, Austria), and the Osaka HIMAK (Osaka, Japan), on the RBE was investigated using OpenGATE10. The microdosimetric spectra were determined using the abridged microdosimetric distribution methodology (AMDM) and input into the MCF microdosimetric kinetic model (MKM) to determine spectral and RBE dependence on nozzle design. Monoenergetic carbon ion beams having a range in water of 3 and 27 cm were simulated. For the 27 cm beams, a simulated water-based range shifter was inserted before the phantom, reducing the range to 3 cm. Furthermore, a shallow spread-out Bragg peak (SOBP) (5-10 cm) and a deep SOBP (15-21 cm), were simulated for all nozzles and the resulting integrated dose profiles compared.</div></div><div><h3>Results</h3><div>For all nozzle geometries, the range at 80% dose fall-off (R80) agreed within 0.1 mm. The lineal energy and the RBE agreed very well until the Bragg peak, after which some differences could be observed. For the SOBPs, the agreement was similar with an agreement in the biological dose before and at the SOBP within 0.7%. For the thick nozzle of Osaka HIMAK, small differences were observed, mostly in the fragmentation tail.</div></div><div><h3>Conclusion</h3><div>The AMDM was successfully integrated into OpenGATE10 and used to compute the RBE with the MCF MKM. It was shown that the nozzle design itself had only a minor effect on the radiation quality and consequently the RBE. A small difference in RBE is observed mostly after the Bragg peak and SOBP in the fragmentation tail and depends on the nozzle water equivalent tissue (WET), when it is a change of more than 24 mm.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 238-246"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vivo corneal microscopy: from image to insight – where are we going?","authors":"Karsten Sperlich,&nbsp;Sebastian Bohn,&nbsp;Florian Worsch,&nbsp;Luisa H. Colorado,&nbsp;Stephan Allgeier,&nbsp;Oliver Stachs","doi":"10.1016/j.zemedi.2025.10.001","DOIUrl":"10.1016/j.zemedi.2025.10.001","url":null,"abstract":"<div><div>In vivo confocal microscopy (IVCM) enables noninvasive imaging of the human cornea at cellular resolution, making it an indispensable diagnostic tool in clinical ophthalmology and biomedical research. The combination of the Heidelberg Retina Tomograph (HRT) and the Rostock Cornea Module (RCM) has established itself as the gold standard for corneal cellular imaging. This review summarizes the imaging principles, technological advancements, and clinical applications of IVCM. It highlights recent advancements, including automated large-area mosaicking of the subbasal nerve plexus, three-dimensional volumetric imaging, time-lapse imaging, and enhanced image analysis techniques. Additionally, corneal immune cell dynamics, critical to understanding corneal pathophysiology, are highlighted. Future challenges and developments aimed at improving diagnostic accuracy and clinical applicability are discussed.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 134-143"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardization of bone mineral density and microstructure from high-resolution CT-scans of the spine in a multicenter setting","authors":"Jaime A. Peña,&nbsp;Reinhard Barkmann,&nbsp;Stefan Reinhold,&nbsp;Timo Damm,&nbsp;Tobias Fricke,&nbsp;Jan Bastgen,&nbsp;Felix Thomsen,&nbsp;Claus-C. Glüer","doi":"10.1016/j.zemedi.2025.04.002","DOIUrl":"10.1016/j.zemedi.2025.04.002","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Purpose&lt;/h3&gt;&lt;div&gt;Quantitative Computed Tomography (QCT) has not fully addressed the need to reduce intra- and inter-scanner variability for Osteoporosis and bone-related studies, which can lead to inaccuracies when pooling data from different CT manufacturers, models, devices, or protocols. In this context, the aim of this work was to develop ex vivo methods for the standardization of bone mineral density and microstructural parameters.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Materials and methods&lt;/h3&gt;&lt;div&gt;Six human vertebral body specimens embedded in poly-methyl methacrylate (PMMA) were scanned ex vivo inside an anthropomorphic abdomen phantom in eight different CT-scanners. We measured 3D trabecular and cortical bone mineral density (Tb.BMD and Ct.BMD at the peeled spongiosa and the vertical cortex, respectively), trabecular separation (Tb.Sp) and cortical thickness (Ct.Th). Standardization of Tb.BMD and Ct.BMD across CT-scanners was conducted by correcting for the influence of PMMA and kernel related differences in the segmented cortical volume. For Tb.BMD and Ct.BMD two CT-scanners, where the majority of the patients were scanned, were used as reference. For Tb.Sp standardization we accounted for the image binarization threshold and used high-resolution peripheral QCT (HR-pQCT) as reference. Cross-calibration factors were obtained for each CT-scanner from which the cross-calibrated measures xTb.BMD, xCt.BMD and xTb.Sp were computed both ex vivo and in vivo. Agreement of the ex vivo measurements with respect to the references was quantified with Lin’s concordance correlation coefficient (r&lt;sub&gt;CCC&lt;/sub&gt;) before and after standardization. For the clinical in vivo part of the study, 152 patients (24M, 128F) undergoing long-term bisphosphonate treatment had their T12 or L1 vertebrae scanned with the same CT-scanners and protocols as for ex vivo. Statistical bone fracture models were conducted before and after cross-calibration to assess the performance of the standardization procedure in vivo.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;After cross-calibration the overall ex vivo mean Tb.BMD across CT-scanners was basically maintained, changing only from 119.0 mgHA/cm&lt;sup&gt;3&lt;/sup&gt; to 119.4 mgHA/cm&lt;sup&gt;3&lt;/sup&gt;. The mean Ct.BMD raised from 420.4 mgHA/cm&lt;sup&gt;3&lt;/sup&gt; to 441.1 mgHA/cm&lt;sup&gt;3&lt;/sup&gt;. Tb.BMD showed a small variability (SD of means) across centers of 2.7 mgHA/cm&lt;sup&gt;3&lt;/sup&gt;. For Ct.BMD additional kernel related thickness correction reduced this variability from 31.7 mgHA/cm&lt;sup&gt;3&lt;/sup&gt; to 22.4 mgHA/cm&lt;sup&gt;3&lt;/sup&gt;. Non-standardized Tb.Sp showed a mean of 2.63 mm across CT-scanners, which after standardization was corrected to 1.18 mm. Agreement to the reference measurements was markedly improved after standardization (before: the r&lt;sub&gt;ccc&lt;/sub&gt; [min, max] for Tb.BMD, Ct.BMD and Tb.Sp was [0.64, 0.92], [0.40, 0.89] and [0.57, 0.99], respectively; after standardization: [0.98, 0.99], [0.96, 0.99] and [0.78, 0.99], respectively). For in vivo, Tb.BMD and Ct.BMD","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 226-237"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deciphering the best shape aspheric intraocular lens – A raytracing based optimisation study","authors":"Achim Langenbucher,&nbsp;Jascha Wendelstein,&nbsp;Alan Cayless,&nbsp;Peter Hoffmann,&nbsp;Nóra Szentmáry","doi":"10.1016/j.zemedi.2025.07.004","DOIUrl":"10.1016/j.zemedi.2025.07.004","url":null,"abstract":"<div><h3>Purpose</h3><div>To develop, implement and demonstrate a calculation strategy to derive the best shape spherical or aspherical intraocular lens (IOL) considering corneal spherical aberration (SA).</div></div><div><h3>Methods</h3><div>The simulation concept is based on 2D raytracing and involves an ideal plano or spherical wavefront with an optical path length correction which simulates corneal SA. The IOL defined with its equivalent power PIOL, Coddington shape factor (CSF) and edge thickness (ET) could be located with its secondary principal plane (PP2) or its haptic plane (HP) at the predicted axial lens position (ELP).The lens geometry is optimised for the root-mean-squared wavefront error (RMSWF) and the best wavefront and rayscatter focus are derived.</div></div><div><h3>Results</h3><div>The custom simulation software package is written in Matlab (version 2024a). The applicability of the simulation software is shown with some examples to show the performance of the results. The simulation results are structured to give some insight into best shape spherical and aspheric lenses, the impact of CSF, corneal spherical aberration to be corrected, and the concept of using the ELP to predict either the PP2 or the HP of the lens.</div></div><div><h3>Conclusions</h3><div>The simulation tool seems to be very robust in optimising best shape spherical and aspherical lenses based on available data for corneal power and spherical aberration. In all examples the spherical aberrations were completely eliminated or reduced to a negligible amount using individually shaped biconvex aspheric IOLs. An implementation in an industrial manufacturing process of customised aspheric lenses and a clinical study are needed to validate the concept in a clinical setting.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 169-178"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deutsches Optisches Museum – edutainment for optics & photonics","authors":"Timo Mappes","doi":"10.1016/j.zemedi.2025.12.002","DOIUrl":"10.1016/j.zemedi.2025.12.002","url":null,"abstract":"<div><div>Currently under construction in Jena, Germany, the Deutsches Optisches Museum (D.O.M.) represents a novel concept in science communication, merging the principles of modern science centers with the heritage of classical museums. Designed as an interactive edutainment hub, the D.O.M. integrates artistic, aesthetic, and scientific approaches to engage the public in optics, photonics, and medical physics. Visitors will be driven to learn through curiosity, visual fascination, and hands-on experimentation, all of which will be complemented by in-depth scientific explanations. Spanning more than 3100 m² across four floors, the museum’s exhibition will be dedicated to microscopy, ophthalmic optics and spectacle lenses, and astronomy. Key highlights include the world’s largest historical glass archive; interactive relay-optics stations that allow visitors to “look through” historical instruments; and large-scale educational models such as a walk-in human eye. The concept unites education, research outreach, and design through collaboration with leading architects, artists, scientists, and industrial partners. Located in the historical and contemporary heart of optical innovation, D.O.M. aims to set a global benchmark for communicating science in the fields of optics and photonics. The museum fosters public understanding and appreciation of the physical principles of optics and photonics that shape both medical and industrial technologies.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"36 2","pages":"Pages 207-211"},"PeriodicalIF":4.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145822624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}