Zeitschrift fur Medizinische Physik最新文献

{"title":"Erratum to “The role of Monte Carlo simulation in understanding the performance of proton computed tomography” [Z Med Phys 32 (2022) 23–38]","authors":"George Dedes , Jannis Dickmann , Valentina Giacometti , Simon Rit , Nils Krah , Sebastian Meyer , Vladimir Bashkirov , Reinhard Schulte , Robert P. Johnson , Katia Parodi , Guillaume Landry","doi":"10.1016/j.zemedi.2024.07.012","DOIUrl":"10.1016/j.zemedi.2024.07.012","url":null,"abstract":"","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Page 109"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “Volumetric 23Na single and triple-quantum imaging at 7T: 3D-CRISTINA” [Z Med Phys 32 (2022) 199–208]","authors":"Michaela A.U. Hoesl , Lothar R. Schad , Stanislas Rapacchi","doi":"10.1016/j.zemedi.2024.07.008","DOIUrl":"10.1016/j.zemedi.2024.07.008","url":null,"abstract":"","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Page 113"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid whole-brain quantitative MT imaging","authors":"Roya Afshari ,&nbsp;Francesco Santini ,&nbsp;Rahel Heule ,&nbsp;Craig H. Meyer ,&nbsp;Josef Pfeuffer ,&nbsp;Oliver Bieri","doi":"10.1016/j.zemedi.2023.02.005","DOIUrl":"10.1016/j.zemedi.2023.02.005","url":null,"abstract":"<div><h3>Purpose</h3><div>To provide a robust whole-brain quantitative magnetization transfer (MT) imaging method that is not limited by long acquisition times.</div></div><div><h3>Methods</h3><div>Two variants of a spiral 2D interleaved multi-slice spoiled gradient echo (SPGR) sequence are used for rapid quantitative MT imaging of the brain at 3 T. A dual flip angle, steady-state prepared, double-contrast method is used for combined B₁ and-T₁ mapping in combination with a single-contrast MT-prepared acquisition over a range of different saturation flip angles (50 deg to 850 deg) and offset frequencies (1 kHz and 10 kHz). Five sets (containing minimum 6 to maximum 18 scans) with different MT-weightings were acquired. In addition, main magnetic field inhomogeneities (ΔB₀) were measured from two Cartesian low-resolution 2D SPGR scans with different echo times. Quantitative MT model parameters were derived from all sets using a two-pool continuous-wave model analysis, yielding the pool-size ratio, F, their exchange rate, k_f, and their transverse relaxation time, T_2r.</div></div><div><h3>Results</h3><div>Whole-brain quantitative MT imaging was feasible for all sets with total acquisition times ranging from 7:15 min down to 3:15 min. For accurate modeling, B₁-correction was essential for all investigated sets, whereas ΔB₀-correction showed limited bias for the observed maximum off-resonances at 3 T.</div></div><div><h3>Conclusion</h3><div>The combination of rapid B₁-T₁ mapping and MT-weighted imaging using a 2D multi-slice spiral SPGR research sequence offers excellent prospects for rapid whole-brain quantitative MT imaging in the clinical setting.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Pages 69-77"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9252608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-contrast free-breathing liver perfusion imaging using velocity selective ASL combined with prospective motion compensation","authors":"Ke Zhang ,&nbsp;Simon M.F. Triphan ,&nbsp;Mark O. Wielpütz ,&nbsp;Christian H. Ziener ,&nbsp;Mark E. Ladd ,&nbsp;Heinz-Peter Schlemmer ,&nbsp;Hans-Ulrich Kauczor ,&nbsp;Oliver Sedlaczek ,&nbsp;Felix T. Kurz","doi":"10.1016/j.zemedi.2024.06.001","DOIUrl":"10.1016/j.zemedi.2024.06.001","url":null,"abstract":"<div><h3>Purpose</h3><div>To apply velocity selective arterial spin labeling (VSASL) combined with a navigator-based (NAV) prospective motion compensation method for a free–breathing liver perfusion measurement without contrast agent.</div></div><div><h3>Methods</h3><div>Sinc-modulated Velocity Selective Inversion (sinc-VSI) pulses were applied as labeling and control pulses. In order to account for respiratory motion, a navigator was employed in the form of a single gradient-echo projection readout, located at the diaphragm along the inferior-superior direction. Prior to each transverse imaging slice of the spin-echo EPI based readouts, navigator and fat suppression were incorporated. Motion data was obtained from the navigator and transmitted back to the sequence, allowing real-time adjustments to slice positioning. The sinc-VSI without velocity-selective gradients during the control condition but with velocity-selective gradients along all three directions during labeling was chosen for the VSASL. The VSASL was compared with pseudo-continuous ASL (pCASL) methods, which selectively tagged the moving spins using a tagging plane placed at the portal vein and hepatic artery.</div></div><div><h3>Results</h3><div>The motion caused by respiratory activity was effectively computed using the navigator signal. The coefficients of variation (CoV) of average liver voxel in NAV were significantly decreased when compared to breath-hold (BH), with an average reduction of 29.4 ± 18.44% for control images, and 29.89 ± 20.83% for label images (p &lt; 0.001). The resulting maps of normalized ASL signal (normalized to M₀) showed significantly higher perfusion weightings in the NAV-compensated VSASL, when compared to the NAV-compensated pCASL techniques.</div></div><div><h3>Conclusions</h3><div>This study demonstrates the feasibility of using a navigator-based prospective motion compensation technique in conjunction with VSASL for the measurement of liver perfusion without the use of contrast agents while allowing for free-breathing.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Pages 87-97"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141500136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Celebrating 35 Years of Zeitschrift für Medizinische Physik","authors":"Jürgen R. Reichenbach (Editor-in-Chief)","doi":"10.1016/j.zemedi.2025.01.001","DOIUrl":"10.1016/j.zemedi.2025.01.001","url":null,"abstract":"","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Pages 1-2"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “Can Generative Adversarial Networks help to overcome the limited data problem in segmentation?” [Z Med Phys 32 (2022) 361–368]","authors":"Gerd Heilemann ,&nbsp;Mark Matthewman ,&nbsp;Peter Kuess ,&nbsp;Gregor Goldner ,&nbsp;Joachim Widder ,&nbsp;Dietmar Georg ,&nbsp;Lukas Zimmermann","doi":"10.1016/j.zemedi.2024.07.006","DOIUrl":"10.1016/j.zemedi.2024.07.006","url":null,"abstract":"","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Page 115"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “Commissioning and quality assurance of a novel solution for respiratory-gated PBS proton therapy based on optical tracking of surface markers” [Z Med Phys 32 (2022) 52–62]","authors":"Giovanni Fattori ,&nbsp;Jan Hrbacek ,&nbsp;Harald Regele ,&nbsp;Christian Bula ,&nbsp;Alexandre Mayor ,&nbsp;Stefan Danuser ,&nbsp;David C. Oxley ,&nbsp;Urs Rechsteiner ,&nbsp;Martin Grossmann ,&nbsp;Riccardo Via ,&nbsp;Till T. Böhlen ,&nbsp;Alessandra Bolsi ,&nbsp;Marc Walser ,&nbsp;Michele Togno ,&nbsp;Emma Colvill ,&nbsp;Daniel Lempen ,&nbsp;Damien C. Weber ,&nbsp;Antony J. Lomax ,&nbsp;Sairos Safai","doi":"10.1016/j.zemedi.2024.07.011","DOIUrl":"10.1016/j.zemedi.2024.07.011","url":null,"abstract":"","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Page 110"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “Free-breathing half-radial dual-echo balanced steady-state free precession thoracic imaging with wobbling Archimedean spiral pole trajectories” [Z Med. Phys. 33 (2023) 220–229]","authors":"Oliver Bieri ,&nbsp;Orso Pusterla ,&nbsp;Grzegorz Bauman","doi":"10.1016/j.zemedi.2024.07.003","DOIUrl":"10.1016/j.zemedi.2024.07.003","url":null,"abstract":"","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Page 117"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quo Vadis MRI?","authors":"Jürgen Hennig","doi":"10.1016/j.zemedi.2024.12.002","DOIUrl":"10.1016/j.zemedi.2024.12.002","url":null,"abstract":"","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Pages 3-5"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142974223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quo Vadis Hyperpolarized 13C MRI?","authors":"Pascal Wodtke ,&nbsp;Martin Grashei ,&nbsp;Franz Schilling","doi":"10.1016/j.zemedi.2023.10.004","DOIUrl":"10.1016/j.zemedi.2023.10.004","url":null,"abstract":"<div><div>Over the last two decades, hyperpolarized ¹³C MRI has gained significance in both preclinical and clinical studies, hereby relying on technologies like PHIP-SAH (ParaHydrogen-Induced Polarization-Side Arm Hydrogenation), SABRE (Signal Amplification by Reversible Exchange), and dDNP (dissolution Dynamic Nuclear Polarization), with dDNP being applied in humans. A clinical dDNP polarizer has enabled studies across 24 sites, despite challenges like high cost and slow polarization. Parahydrogen-based techniques like SABRE and PHIP offer faster, more cost-efficient alternatives but require molecule-specific optimization. The focus has been on imaging metabolism of hyperpolarized probes, which requires long <em>T₁</em>, high polarization and rapid contrast generation. Efforts to establish novel probes, improve acquisition techniques and enhance data analysis methods including artificial intelligence are ongoing. Potential clinical value of hyperpolarized ¹³C MRI was demonstrated primarily for treatment response assessment in oncology, but also in cardiology, nephrology, hepatology and CNS characterization. In this review on biomedical hyperpolarized ¹³C MRI, we summarize important and recent advances in polarization techniques, probe development, acquisition and analysis methods as well as clinical trials. Starting from those we try to sketch a trajectory where the field of biomedical hyperpolarized ¹³C MRI might go.</div></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":"35 1","pages":"Pages 8-32"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139068000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}