International Journal for Parasitology-Parasites and Wildlife最新文献

{"title":"Molecular detection of Cryptosporidium parvum in wild rodents (Phyllotis darwini) inhabiting protected and rural transitional areas in north-central Chile","authors":"Patricio D. Carrera-Játiva ,&nbsp;Gerardo Acosta-Jamett ,&nbsp;Pamela Muñoz","doi":"10.1016/j.ijppaw.2024.100971","DOIUrl":"10.1016/j.ijppaw.2024.100971","url":null,"abstract":"<div><p>Wild rodents often harbor <em>Cryptosporidium</em> species that can be transmitted to multiple mammal hosts. In Chile, little is known about <em>Cryptosporidium</em> in wild rodents, and available studies have been focused on morphological findings with no molecular-based evidence. A longitudinal survey was conducted between 2021 and 2022 to investigate the occurrence of <em>Cryptosporidium</em> spp. in populations of the Darwin's leaf-eared mouse (<em>Phyllotis darwini</em>) living in protected and rural transitional areas in north-central Chile, using staining and molecular methods. A total of 247 fecal samples were collected and examined by the modified Ziehl–Neelsen (ZN) staining test, 54 of which were positive for <em>Cryptosporidium</em>-like oocysts. Molecular analyses were carried out by PCR of the partial 18S ribosomal RNA and 60 kDa glycoprotein (<em>gp60</em>) genes. <em>Cryptosporidium</em> infection was confirmed in 34 samples (13.7 %) based on the PCR amplification, and individual (i.e., sex, and body mass index) and ecological variables (i.e., type of site and season) were not statistically significant (p &gt; 0.05). Using the nucleotide sequencing of the partial 18S rRNA gene, <em>Cryptosporidium parvum</em> was identified in nine isolates. Also, <em>C. parvum</em> subgenotype family <em>IIa</em> was determined in seven samples by the partial <em>gp60</em> gene, including the subtype <em>IIaA17G4R1</em> in two samples<em>.</em> This is the first molecular evidence of <em>Cryptosporidium parvum IIa</em> in <em>Phyllotis darwini</em> in Chile. These results indicate potential cross-species transmition between wild rodents and domestic-wild animals in north-central Chile. More research is needed to understand better the role of wild rodents in the transmission of <em>Cryptosporidium</em> spp. in Chile.</p></div>","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"24 ","pages":"Article 100971"},"PeriodicalIF":2.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000671/pdfft?md5=0c9d82badc2ec5ba82e546a136780348&pid=1-s2.0-S2213224424000671-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141947455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Outbreak of parasite-induced limb malformations in a declining amphibian species in Colorado” [Int. J. Parasitol.: Parasites Wildl. 24, August (2024), 100965]","authors":"Pieter T.J. Johnson ,&nbsp;Dana M. Calhoun ,&nbsp;Tyler J. Achatz ,&nbsp;Stephen E. Greiman ,&nbsp;Adrian Gestos ,&nbsp;William H. Keeley","doi":"10.1016/j.ijppaw.2024.100970","DOIUrl":"10.1016/j.ijppaw.2024.100970","url":null,"abstract":"","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"24 ","pages":"Article 100970"},"PeriodicalIF":2.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221322442400066X/pdfft?md5=3449cbaf1b03f3a9d605e90d996da7cd&pid=1-s2.0-S221322442400066X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141947457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Unexpected absence of exo-erythrocytic merogony during high gametocytaemia in two species of Haemoproteus (Haemosporida: Haemoproteidae), including description of Haemoproteus angustus n. sp. (lineage hCWT7) and a report of previously unknown residual bodies during in vitro gametogenesis” [Int. J. Parasitol.: Parasites and Wildlife 23 (April 2024) 100905]","authors":"Gediminas Valkiūnas ,&nbsp;Tatjana Iezhova ,&nbsp;Mikas Ilgūnas ,&nbsp;Mélanie Tchoumbou ,&nbsp;Mélanie Duc ,&nbsp;Dovilė Bukauskaitė ,&nbsp;Tanja Himmel ,&nbsp;Josef Harl ,&nbsp;Herbert Weissenböck","doi":"10.1016/j.ijppaw.2024.100936","DOIUrl":"10.1016/j.ijppaw.2024.100936","url":null,"abstract":"","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"24 ","pages":"Article 100936"},"PeriodicalIF":2.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000324/pdfft?md5=a0d6b2938c8d9d459e7370b8d83ea403&pid=1-s2.0-S2213224424000324-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141947459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equal rights for parasites: Are we there yet?","authors":"","doi":"10.1016/j.ijppaw.2024.100945","DOIUrl":"10.1016/j.ijppaw.2024.100945","url":null,"abstract":"","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"24 ","pages":"Article 100945"},"PeriodicalIF":2.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000415/pdfft?md5=25d704830cb6682630c434afafc4d04a&pid=1-s2.0-S2213224424000415-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141035060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular evaluation of Eimeria spp. Infection in the Volga-Ural Saiga antelope population of the Republic of Kazakhstan","authors":"Erzhan Zh Kidiraliyev ,&nbsp;Ainur A. Zhaksylykova ,&nbsp;Eleonora A. Kydyrkhanova ,&nbsp;Kaissar Zh Kushaliyev ,&nbsp;Alexandr Shevtsov ,&nbsp;Ryskeldina Anara ,&nbsp;Zhibek P. Sembaeva ,&nbsp;M.A. Arzybaev ,&nbsp;Christine M. Budke ,&nbsp;Aida M. Abdybekova","doi":"10.1016/j.ijppaw.2024.100966","DOIUrl":"10.1016/j.ijppaw.2024.100966","url":null,"abstract":"<div><p>Saiga antelope (<em>Saiga tatarica</em>) is a protected species in Kazakhstan. Little is known about the parasitofauna of these mammals. Therefore, the focus of this study was to evaluate the prevalence and species diversity of <em>Eimeria</em> spp. infection in the Volga-Ural Saiga antelope population. In June 2023, 104 Saiga antelope fecal samples collected from the district of Zhanibek, located in the province of West Kazakhstan were evaluated using microscopic and molecular techniques. Based on coprovoscopy results, <em>Eimeria</em> spp. Oocysts were present in 22 samples (21%). The four fecal samples containing the largest numbers of <em>Eimeria</em> spp. Oocysts per 10x field were selected for further genetic analysis. DNA extraction, nested PCR amplification, and sequencing were performed on 91 clones, with 80 clones forming a distinct clade and exhibiting genetic similarity to MT801034 Ei<em>meria</em> sp. Voucher HY3. These clones possibly represent an <em>Eimeria</em> specific to Saiga antelopes and gazelle that has previously been morphologically described as <em>Eimeria elegans</em> (Svanbaev, 1979), underscoring the importance of further research into parasitic infections in this protected species.</p></div>","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"24 ","pages":"Article 100966"},"PeriodicalIF":2.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000622/pdfft?md5=1bfc6c3b623bab3d9b3cca7d9c6ce1cb&pid=1-s2.0-S2213224424000622-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141703516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First record and description of actinospore stages (raabeia, triactinomyxon, and aurantiactinomyxon types) of fish parasitic myxozoans from Malaysia","authors":"Nadhirah Syafiqah Suhaimi ,&nbsp;Boglárka Sellyei ,&nbsp;Gábor Cech ,&nbsp;Csaba Székely ,&nbsp;Muhammad Hafiz Borkhanuddin","doi":"10.1016/j.ijppaw.2024.100964","DOIUrl":"10.1016/j.ijppaw.2024.100964","url":null,"abstract":"<div><p>During a 2-month survey in 2023 at Tasik Telabak, Terengganu, Malaysia three distinct actinospore types, namely raabeia, triactinomyxon and aurantiactinomyxon were identified in three invertebrate host species: <em>Aulodrilus acutus</em>, <em>Branchiodrilus</em> sp., and <em>Bothrioneurum</em> sp. utilizing morphometric and molecular analyses<em>.</em> Maximum likelihood of 18S rDNA positioned the raabeia type within the <em>Myxobolus</em> clade from fish of the Order Cypriniformes, suggesting a detected actinospore has a potential life cycle development in Cypriniformes and the genus <em>Myxobolus</em>. Both triactinomyxon and aurantiactinomyxon types were described solely based on morphology and morphometrics due to preservation error preventing the acquisition of 18S rDNA sequences. The triactinomyxon type in this study exhibited distinct morphology in spore shape and dimensions, characterized by a short style and caudal processes. Conversely, the aurantiactinomyxon type described herein possesses prominent elongated pyriform polar capsules not resembling any previously known aurantiactinomyxon types. These distinctive features, along with host species and geographical location justify their classification as novel types. Histological and microscopic analyses revealed the development of pansporocysts in the intestinal epithelium of the oligochaete host. This study marks the first descriptions of actinospore stages of myxozoans in Malaysia and the initial report of actinospores infecting host species of <em>Aulodrilus acutus</em>, <em>Branchiodrilus</em> sp. and <em>Bothrioneurum</em> sp.</p></div>","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"24 ","pages":"Article 100964"},"PeriodicalIF":2.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000609/pdfft?md5=3b1e2e696443f43c5f6e00c57e3895f5&pid=1-s2.0-S2213224424000609-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141623779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anticoccidial activity of the secondary metabolites in alpine plants frequently ingested by wild Japanese rock ptarmigans","authors":"Asako Haraguchi ,&nbsp;Jyunki Nagasawa ,&nbsp;Kouji Kuramochi ,&nbsp;Sayaka Tsuchida ,&nbsp;Atsushi Kobayashi ,&nbsp;Toshimitsu Hatabu ,&nbsp;Kazumi Sasai ,&nbsp;Hiromi Ikadai ,&nbsp;Kazunari Ushida ,&nbsp;Makoto Matsubayashi","doi":"10.1016/j.ijppaw.2024.100967","DOIUrl":"10.1016/j.ijppaw.2024.100967","url":null,"abstract":"<div><p>The Japanese rock ptarmigan (<em>Lagopus muta japonica</em>) is an herbivorous species of partridges that inhabits only alpine zones. Alpine plants are their main source of food. These alpine plants contain toxic compounds to deter herbivores from consuming them. A previous analysis of the alpine plants frequently consumed by Japanese rock ptarmigans revealed the presence of a unique mixture of secondary metabolites and a novel compound. Additionally, wild Japanese rock ptarmigans are often infected by two species of <em>Eimeria</em> parasites. When these parasites were experimentally administered to Svalbard rock ptarmigans (<em>Lagopus muta hyperborean</em>), which do not feed on alpine plants, the birds exhibited symptoms, such as diarrhea and depression, and in some cases, they died. Although little is known about the pathogenesis of these parasites in wild Japanese rock ptarmigans, it was hypothesized that compounds found in alpine plants, their main food source, may reduce the pathogenicity of <em>Eimeria</em> parasites. In the present study, we evaluated the anticoccidial activity of the compounds derived from alpine plants <em>in vitro</em> using <em>Eimeria tenella</em>, which infects chickens belonging to the same pheasant family, as an experimental model. Twenty-seven natural components were extracted from eight alpine plants. The natural components were added to <em>E. tenella</em> sporozoites and incubated for 24 h to evaluate their direct effect. Additionally, Madin-Darby bovine kidney cells were incubated with sporozoites and natural components for 24 h to evaluate the inhibitory effect of the components on sporozoite cell invasion. Six compounds from four alpine plants decreased sporozoite viability by up to 88.3%, and two compounds inhibited sporozoite invasion into the cells. Although further studies are needed to evaluate the effects of these components against <em>Eimeria</em> infections <em>in vivo</em>, our findings suggest that these alpine plants may reduce the degree of infection by decreasing the number of sporozoites in the intestinal tract.</p></div>","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"25 ","pages":"Article 100967"},"PeriodicalIF":2.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000634/pdfft?md5=3f8d23fb24a0c6750608d30d4b4bd4a4&pid=1-s2.0-S2213224424000634-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141706065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outbreak of parasite-induced limb malformations in a declining amphibian species in Colorado","authors":"Pieter T.J. Johnson ,&nbsp;Dana M. Calhoun ,&nbsp;Tyler J. Achatz ,&nbsp;Stephen E. Greiman ,&nbsp;Adrian Gestos ,&nbsp;William H. Keeley","doi":"10.1016/j.ijppaw.2024.100965","DOIUrl":"10.1016/j.ijppaw.2024.100965","url":null,"abstract":"<div><p>The detection of severe limb malformations in metamorphosing northern leopard frogs (<em>Rana pipiens</em>) from a Colorado pond in August 2022 prompted questions about the cause(s) and concern over the implications. Northern leopard frogs, which are a Tier 1 Species of Greatest Conservation Need in Colorado, have declined over much of their range in the state, particularly along the Front Range. Although malformations in amphibians have been reported in other parts of the USA, they are rare in Colorado, and the current case represents the most severe hotspot reported in the state for over 70 years. Across three survey events in late summer and early fall of 2022, approximately 68% of captured leopard frogs (late-stage larvae and metamorphic frogs) exhibited one or more malformations. Malformations exclusively affected the hind limbs and were dominated by skin webbings (51.7% of the total), bony triangles (32.2%), and extra limbs or digits (11%). Many animals had multiple malformations that limited the movement of one or both limbs (average of 2.3 malformations per malformed frog). Dissection of a subset of animals coupled with 28S rDNA genetic sequencing revealed the occurrence of the trematode <em>Ribeiroia ondatrae</em> at an average of 75.2 trematode cysts (metacercariae) per frog. The parasite was also detected in 2.6% of dissected snails (<em>Helisoma trivolvis</em>), which function as the trematode's first intermediate host. The relatively high loads of infection detected here – coupled with the similarity of observed malformations to those previously linked to <em>R. ondatrae</em> in experimental studies and from other malformation hotspots in the USA – offer compelling evidence that the current case is the result of parasite infection. Unresolved questions include why malformation prevalence was so high in 2022 and the degree to which such abnormalities will affect population persistence for local leopard frogs, particularly if malformations continue.</p></div>","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"24 ","pages":"Article 100965"},"PeriodicalIF":2.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000610/pdfft?md5=ab4a42b455f4f2e842753e7b8181100b&pid=1-s2.0-S2213224424000610-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elucidating nematode diversity and prevalence in moose across a wide latitudinal gradient using DNA metabarcoding","authors":"Jason L. Anders ,&nbsp;Marie Davey ,&nbsp;Bram Van Moorter ,&nbsp;Frode Fossøy ,&nbsp;Sanne Boessenkool ,&nbsp;Erling J. Solberg ,&nbsp;Erling L. Meisingset ,&nbsp;Atle Mysterud ,&nbsp;Christer M. Rolandsen","doi":"10.1016/j.ijppaw.2024.100962","DOIUrl":"https://doi.org/10.1016/j.ijppaw.2024.100962","url":null,"abstract":"<div><p>Parasitic nematodes are ubiquitous and can negatively impact their host by reducing fecundity or increasing mortality, yet the driver of variation in the parasite community across a wildlife host's geographic distribution remains elusive for most species. Based on an extensive collection of fecal samples (n = 264) from GPS marked moose (<em>Alces alces</em>), we used DNA metabarcoding to characterize the individual (sex, age class) and seasonal parasitic nematode community in relation to habitat use and migration behavior in five populations distributed across a wide latitudinal gradient (59.6°N to 70.5°N) in Norway. We detected 21 distinct nematode taxa with the six most common being <em>Ostertagia</em> spp., <em>Nematodirella</em> spp., <em>Trichostongylus</em> spp., <em>T</em>. <em>axei</em>, <em>Elaphostrongylus alces,</em> and an unclassified Strongylida. There was higher prevalence of livestock parasites in areas with larger sheep populations indicating a higher risk of spillover events. The individual level nematode richness was mostly consistent across study areas, while the number and type of nematode taxa detected at each study area varied considerably but did not follow a latitudinal gradient. While migration distance affected nematode beta-diversity across all sites, it had a positive effect on richness at only two of the five study areas suggesting population specific effects. Unexpectedly, nematode richness was higher in winter than summer when very few nematodes were detected. Here we provide the first extensive description of the parasitic nematode community of moose across a wide latitudinal range. Overall, the population-specific impact of migration on parasitism across the distribution range and variation in sympatry with other ruminants suggest local characteristics affect host-parasite relationships.</p></div>","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"24 ","pages":"Article 100962"},"PeriodicalIF":2.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000580/pdfft?md5=8615148950847878920f7c73cb071c79&pid=1-s2.0-S2213224424000580-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141595305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acanthoatractis xinguensis n. gen., n. sp. (Nematoda: Cosmocercoidea: Atractidae) parasite of yellow-spotted Amazon river turtle, Podocnemis unifilis Troschel (Testudines: Podocnemididae) in Brazilian Amazon","authors":"Ronald Ferreira Jesus,&nbsp;Bianca Nandyara,&nbsp;Jeannie Nascimento dos Santos,&nbsp;Francisco Tiago de Vasconcelos Melo","doi":"10.1016/j.ijppaw.2024.100961","DOIUrl":"https://doi.org/10.1016/j.ijppaw.2024.100961","url":null,"abstract":"<div><p>Nematodes collected from the stomach of the yellow-spotted turtle <em>Podocnemis unifilis</em> Troschel, 1848 (Testudinidae) in the Brazilian state of Pará are assigned to a new genus, allocated to the family Atractidae (Cosmocerdoidea). <em>Acanthoatractis</em> n. gen. differs from all other genera of Atractidae based on the combination of the following morphological characters: cephalic extremity surrounded by eight bifurcated, wrench-shaped sclerotized structures arranged in a circle; oral opening encircled by two sclerotized pieces with pointed ends and a median portion with a pair of hooks; in males the larger (left) spicule is narrower in the middle third and the gubernaculum is absent. The type species, <em>Acanthoatractis xinguensis</em> n. gen., n. sp., has nine pairs of caudal papillae and a single papilla anterior to the cloacal lip. The new species is the seventh record of an atractid genus parasitizing <em>P. unifilis</em>.</p></div>","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"24 ","pages":"Article 100961"},"PeriodicalIF":2.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000579/pdfft?md5=5205e4d96262033c60379e0be7934078&pid=1-s2.0-S2213224424000579-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141595302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}