SLAS Technology最新文献

{"title":"Contrast-enhanced ultrasonography combined with microbubbles for uterine disorders: Current trends and future perspectives","authors":"Jian Ding ,&nbsp;Wenhai Wang ,&nbsp;Wenbin Zhang ,&nbsp;Yinping Pan ,&nbsp;Dexin Xu","doi":"10.1016/j.slast.2025.100301","DOIUrl":"10.1016/j.slast.2025.100301","url":null,"abstract":"<div><div>Uterine disorders, including fibroids, polyps, and carcinomas, represent significant health concerns for women. Conventional diagnostic methods, including ultrasound and magnetic resonance imaging, often lack the sensitivity required to accurately delineate and evaluate these lesions. Consequently, there is a growing need for advanced imaging techniques to enhance both diagnostic precision and therapeutic decision-making. Standard imaging modalities typically provide low resolution, limiting their effectiveness in evaluating uterine pathology and determining optimal treatment strategies. In this context, microbubbles combined with contrast-enhanced ultrasonography offer a promising solution. This technique enhances the visualization of vascular patterns and tissue perfusion, facilitating a more accurate assessment of uterine lesions. Contrast-enhanced ultrasonography is less invasive, is more cost-effective, and offers real-time evaluation of vascular characteristics, making it a valuable tool for diagnosing uterine abnormalities. This review explores the clinical utility of contrast-enhanced ultrasonography with microbubbles in uterine diseases, focusing on its diagnostic accuracy, comparison with traditional imaging techniques, and its potential to improve the management of uterine pathology.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100301"},"PeriodicalIF":2.5,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143917498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alpha test 1 robotic platform for traditional Chinese medicine pretreatment: Automated modular integration and quality control applications","authors":"Lifei Gu ,&nbsp;Jiaxin Ma ,&nbsp;Lina Zeng ,&nbsp;Junyao Li ,&nbsp;Bing Wang ,&nbsp;Chang Su ,&nbsp;Shuhong Wang","doi":"10.1016/j.slast.2025.100300","DOIUrl":"10.1016/j.slast.2025.100300","url":null,"abstract":"<div><div>Sample pretreatment plays an important role in analytical performance, but it is often the rate-limiting step in scientific research. With the development of automation technology, automated sample preparation has become a powerful tool for liberating labor and improving efficiency. In this study, the automatic pretreatment of traditional Chinese medicine test was realized by module combination, and an intelligent robotic platform Alpha Test 1 was developed to decompose the complex preparation method of traditional Chinese medicine into automatic modular components. It includes a multi-channel liquid feeding device, an extraction bottle device, a reflux condensing pipe ring, a reflux extraction and a water bath extraction device. Each module is connected through modular combinations such as liquid injection control, intelligent sorting, and water bath condensation, and the difficulty of manual operation is gradually tackled to achieve the goal of replacing manual labor in the pretreatment process. We selected two representative traditional Chinese medicines, Xianglian Pills and Erzhi Pills, to explore their application in the testing of traditional Chinese medicine. The results of Alpha Test 1 in the identification and content determination met the requirements of Chinese Pharmacopoeia, and the operation was simple, rapid and efficient compared with the manual pretreatment method. This method can meet the requirements of daily laboratory testing and provide technical support for the quality control evaluation and testing of traditional Chinese medicine.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100300"},"PeriodicalIF":2.5,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143928470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the Efficacy of Invasive Mechanical Ventilation in ICU Patients with Severe Heart Failure","authors":"Darina Bao ,&nbsp;Xin Wang ,&nbsp;Chen Zhou ,&nbsp;Xiaofei Liu ,&nbsp;Yanmei Liu","doi":"10.1016/j.slast.2025.100302","DOIUrl":"10.1016/j.slast.2025.100302","url":null,"abstract":"<div><div>In order to study the clinical treatment effect and analyze the main clinical effects of invasive mechanical ventilation in ICU patients with severe heart failure, this paper proposes a efficacy analysis method based on invasive mechanical ventilation for ICU patients with severe heart failure. This study used a retrospective analysis to select 50 patients with severe heart failure admitted to the ICU of a certain hospital from January 2021 to March 2022 as the research subjects, divided into a control group and an observation group. The control group received conventional treatment methods, while the observation group received invasive mechanical ventilation treatment in addition to conventional treatment, and a nursing quality index system was constructed to verify the feasibility and scientificity of the treatment plan. The research results showed that the treatment effectiveness rate of the observation group was 96%, significantly higher than the control group's 84%. In addition, the arterial oxygen saturation (SaO ₂) and partial pressure of oxygen (PaO ₂) in the observation group were significantly increased after treatment compared to the control group, while the partial pressure of carbon dioxide (PaCO ₂) was lower (P&lt;0.05). In addition, in order to improve the comprehensiveness of the analysis, this study further explored the epidemiological characteristics of patients with severe heart failure, including the influence of age, complications (such as diabetes, hypertension, etc.), course characteristics and other factors on the treatment effect. At the same time, an in-depth analysis was conducted on the application strategies of invasive mechanical ventilation in the treatment of severe heart failure, including airway management, ventilator mode optimization, complication prevention, and nursing measures. In addition, this study compared the applicability of invasive and non-invasive mechanical ventilation in the treatment of severe heart failure patients and evaluated the impact of different mechanical ventilation strategies on patient prognosis. To sum up, this study shows that invasive mechanical ventilation can significantly improve the treatment effect of patients with severe heart failure in ICU, improve the oxygenation level and reduce carbon dioxide retention, while optimizing the quality of care and improving the survival rate. The conclusion of this study provides a reference for clinical practice and proposes exploration directions for further optimizing mechanical ventilation strategies in the future.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100302"},"PeriodicalIF":2.5,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The application of natural language processing technology in hospital network information management systems: Potential for improving diagnostic accuracy and efficiency","authors":"Shiyong Wang ,&nbsp;Hong Luo","doi":"10.1016/j.slast.2025.100287","DOIUrl":"10.1016/j.slast.2025.100287","url":null,"abstract":"<div><h3>Background</h3><div>Processing scanned documents in electronic health records (EHR) was one of the problem in hospital network information management systems (HNIMS). To overcome this difficulty, the complex interactions among natural language processing (NLP), optical character recognition (OCR) and image preprocessing was used.</div></div><div><h3>Objective</h3><div>The goal is to investigate the possibilities of improving diagnostic efficiency and accuracy in healthcare settings by using NLP technologies into HNIMS. These individuals received diagnoses for a wide range of sleep problems. The data collected were converted into scanned PDF images which were then preprocessed by using gray scaling and OCR. Bag of Words (BoW) is used to extract the featured data.</div></div><div><h3>Method</h3><div>Reports are divided among 70 % training and 30 % test sets for NLP model evaluation. By employing a hidden Bayesian technique on the development set, we suggest a novel hidden Bayesian integrated dense Bi-LSTM (HB-DBi-LSTM) strategy for optimizing bag-of-words models. A 6:1 ratio is further separated for training and validation sets in deep learning-based sequence models because of their high computing requirements. After 100 epochs of Adam optimization, the dense Bi-LSTM model is trained.</div></div><div><h3>Result</h3><div>The models are evaluated assessed at the segment level for AHI and SaO2 for ROC and AUROC on test sets. In the finding assessment phase, the detection capacity of the suggested model is evaluated using many criteria, such as F1-score (0.9637), accuracy (0.9321), recall (0.9421) and precision (0.9532). To evaluate information extraction, a document-level examination is also carried out.</div></div><div><h3>Conclusion</h3><div>To improve diagnostic speed and accuracy, especially when handling scanned documents in EHR, it emphasizes the critical need for strong natural language processing (NLP) systems inside HNIMS.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100287"},"PeriodicalIF":2.5,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NLP for computational insights into nutritional impacts on colorectal cancer care","authors":"Shengnan Gong ,&nbsp;Xiaohong Jin ,&nbsp;Yujie Guo ,&nbsp;Jie Yu","doi":"10.1016/j.slast.2025.100295","DOIUrl":"10.1016/j.slast.2025.100295","url":null,"abstract":"<div><div>Colorectal cancer (CRC) is one of the most prominent cancers globally, with its incidence rising among younger adults due to improved screening practices. However, existing algorithms for CRC prediction are frequently trained on datasets that primarily reflect older persons, thus limiting their usefulness in more diverse populations. Additionally, the part of nutrition in CRC deterrence and management is gaining significant attention, although computational approaches to analyzing the impact of diet on CRC remain underdeveloped. This research introduces the Nutritional Impact on CRC Prediction Framework (NICRP-Framework), which combines Natural Language Processing (NLP) techniques with Adaptive Tunicate Swarm Optimized Large Language Models (ATSO-LLMs) to present important insights into the part of the diet in CRC care across diverse populations. The colorectal cancer dietary and lifestyle dataset, encompassing &gt;1000 participants, is collected from multiple regions and sources. The dataset includes structured and unstructured data, including textual descriptions of food ingredients. These descriptions are processed using standardization techniques, such as stop word removal, lowercasing, and punctuation elimination. Relevant terms are then extracted and visualized in a word cloud. The dataset also contained an imbalanced binary CRC outcome, which is rebalanced utilizing the random oversampling. ATSO-LLMs are employed to analyze the processed dietary data, identifying key nutritional factors and forecasting CRC and non-CRC phenotypes based on dietary patterns. The results show that combining NLP-derived features with ATSO-LLMs significantly enhances prediction accuracy (98.4 %), sensitivity (97.6 %) specificity (96.9 %) and F1-Score (96.2 %), with minimal misclassification rates. This framework represents a transformative advancement in life science by offering a new, data-driven approach to understanding the nutritional determinants of CRC, empowering healthcare professionals to make more precise predictions and adapted dietary interventions for diverse populations.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100295"},"PeriodicalIF":2.5,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143860570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanics-based Gradient Nano-surface Implants Screening and Its Adoption in Dental Implant Repair","authors":"Wei Niu ,&nbsp;Xin Wang ,&nbsp;Tao Li ,&nbsp;Bo Feng","doi":"10.1016/j.slast.2025.100293","DOIUrl":"10.1016/j.slast.2025.100293","url":null,"abstract":"<div><h3>Background</h3><div>this study aimed to screen the micro/nano surface of pure titanium implant gradient for performance analysis, and to explore its role in dental implant repair.</div></div><div><h3>Methods</h3><div>after treatment with different concentrations of hydrofluoric acid and varying etching times, titanium plates with micro/nano gradient surfaces were selected and divided into four groups: polished, b, c, and d. The microscopic morphology of the titanium surfaces was observed, and the contact angle was measured. One implant was inserted into the femoral metaphysis on both sides of 28 SD rats. Histological sections were analyzed, and the maximum pull-out force was measured.</div></div><div><h3>Results</h3><div>the new bone trabeculae on the surfaces of groups b, c, and d were wider as against polished group. The surface morphology of the titanium disks etched with 1.2 % hydrofluoric acid for 15 min (group d) was more uniform, the diameter of micropores was the largest, and the contact angle was the smallest (12.1 ± 1.17°). The new bone structure on the surface of implant screws in group d was slightly higher as against groups b and c. The bone-to-implant contact (BIC) and the maximum pullout force in groups b (33.25±2.57 %, 58.52±4.03 N), c (35.16±2.35 %, 59.43±3.97 N), d (40.93±2.71 %, 68.22±4.36 N) were higher as against polished group (22.41±2.86 %, 30.12±4.71 N) (<em>P</em> &lt; 0.05). Three months after implantation, the bone fusion rate in the other three groups was significantly higher than that in the polishing group, with group d showing higher rates compared to groups b and c (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>the gradient micro/nano surface was constructed by hydrofluoric acid. The osseointegration of hydrofluoric acid etching implant surface and implant was clearly better as against polished group.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100293"},"PeriodicalIF":2.5,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-layered data framework for enhancing postoperative outcomes and anaesthesia management through natural language processing","authors":"Peng Xu","doi":"10.1016/j.slast.2025.100294","DOIUrl":"10.1016/j.slast.2025.100294","url":null,"abstract":"<div><div>Anaesthesia management is a critical aspect of perioperative care, directly influencing postoperative recovery, pain management, and patient outcomes. Despite advancements in anaesthesia techniques, variability in patient responses and unexpected postoperative complications remain significant challenges. The research proposes a multi-layered architecture named Anaesthesia CareNet for analyzing data from diverse sources to enhance personalized anaesthesia management and postoperative outcome prediction. The architecture is structured into two primary layers: Data processing and Predictive Modeling. In the Data processing layer, advanced Natural Language Processing (NLP) techniques such as Named Entity Recognition (NER), normalization, lemmatization, and stemming are applied to clean and standardize the unstructured clinical data. Generative Pre-trained Transformer 3 (GPT-3), a Large Language Model (LLM) is employed as a feature extraction method, allowing the system to process and analyze complex clinical narratives and unstructured textual data from patient records. This enables more precise and personalized predictions, not only improving anaesthesia management but also laying the groundwork for broader applications in life sciences. The extracted data is passed into the predictive modeling layer, where the Intelligent Golden Eagle Fine-Tuned Logistic Regression (IGE-LR) model is applied. By analyzing correlations between patient characteristics, surgical details, and postoperative recovery patterns, IGE-LR enables the prediction of complications, pain management requirements, and recovery trajectories beyond anaesthesia; the methodology has potential applications in diverse areas such as diagnostics, drug discovery, and personalized medicine, where large-scale data analysis, predictive modeling, and real-time adaptability are crucial for improving patient outcomes. The proposed IGE-LR method achieves higher performance with 91.7 % accuracy, 90.6 % specificity, and 90 % AUC, with a recall of 91.3 %, precision of 90.1 %, and an F1-Score of 90.4 %. By leveraging advanced NLP and predictive analytics, Anaesthesia CareNet exemplifies how AI-driven frameworks can transform life sciences, advancing personalized healthcare and creating a more precise, efficient, and dynamic approach to treatment management.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100294"},"PeriodicalIF":2.5,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The predictive value of chest CT combined with peripheral blood CD4/CD8 in patients with cerebral infarction complicated with pulmonary infection","authors":"Haojie Wu,&nbsp;Jijing Zheng,&nbsp;Jianhua Zhang","doi":"10.1016/j.slast.2025.100288","DOIUrl":"10.1016/j.slast.2025.100288","url":null,"abstract":"<div><div>To investigate the predictive value of chest computed tomography (CT) combined with peripheral blood CD4/CD8 in patients with cerebral infarction complicated with pulmonary infection. Lung consolidation, tree and bud sign, focus calcification ratio, C-reactive protein (CRP), procalcitonin (PCT), and interleukin-6 (IL-6) were significantly higher in the infected group than in the non-infected group, and CD4 and CD4/CD8 were significantly lower than in the non-infected group (<em>P</em> &lt; 0.05). The results of stratified regression analysis showed that CRP, PCT, IL-6, lung consolidation, tree and bud sign, and calcification all had significant negative effects on CD4/CD8 (<em>t</em>=-5.875, -3.441, -10.406, -7.741, -3.977, -6.547, all <em>P</em> &lt; 0.05). Lung consolidation, tree and bud signs, calcifications, elevated CRP, elevated PCT, and elevated IL-6 were risk factors for patients with pulmonary infection, and increased CD4/CD8 was a protective factor (<em>P</em> &lt; 0.05). There was a non-linear dose-response relationship between CD4/CD8 and the risk of concurrent pulmonary infection (<em>P</em>_{non-linearity}=0.037), with a cut-off value of 0.98. The sensitivity, specificity, positive predictive value, and negative predictive value of combined diagnosis were significantly higher than CD4/CD8 (<em>χ</em>²=6.098, 4.640, 4.643, 6.076, <em>P</em> = 0.014, 0.031, 0.031, 0.014), and the area under the ROC curve of combined diagnosis was significantly higher than chest CT and peripheral blood CD4/CD8 (<em>Z</em> = 4.018, 5.112, <em>P</em> = 0.046, 0.037). Thoracic CT combined with peripheral blood CD4/CD8 can improve the diagnostic efficiency of cerebral infarction patients complicated with pulmonary infection and provide reference for clinical diagnosis and treatment.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100288"},"PeriodicalIF":2.5,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143826452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nano TiO2 photocatalytic combined with optimized operating room care in postoperative infection after gynecological open abdominal surgery","authors":"Fang Yan ,&nbsp;YuXuan Qi","doi":"10.1016/j.slast.2025.100291","DOIUrl":"10.1016/j.slast.2025.100291","url":null,"abstract":"<div><h3>Background</h3><div>Disinfection of the operating room environment is essential to reduce the incidence of infection after laparotomy in obstetrics and gynecology. With the development of science and technology, nano-titanium dioxide (TiO2) photocatalytic technology has attracted much attention due to its high efficiency and low cost. To explore the effect of TiO2 photocatalytic technology and optimized operating room care in the prevention of postoperative infection in obstetrics and gynecology department.</div></div><div><h3>Methods</h3><div>Nano-TiO2 photocatalysts were prepared and characterized, and their bactericidal effect was analyzed. A total of 96 patients with gynecological open abdominal surgery were randomly divided into control group (CG) and observation group (BG), 48 cases in each group. The CG received routine care and the BG received optimized care. The wound healing rate, infection rate, serum immunoglobulin, and inflammatory factor levels were compared.</div></div><div><h3>Results</h3><div>The specific surface area of the nano-TiO2 photocatalyst was 75.1 m²/g, and the particle size was 16.6 nm, with rutile crystal structure. Compared with ultraviolet light, nano-TiO2 photocatalyst had better disinfection effect. Compared with the CG, the wound healing rate and IgG level were higher, and the infection rate, C-reactive protein, interleukin-6, and tumor necrosis factor-α were lower in the BG (<em>P</em> &lt; 0.05).</div></div><div><h3>Conclusion</h3><div>The combination of nano-TiO2 photocatalytic disinfection and optimized nursing care resulted in a 16.66 % reduction in postoperative infections and a 14.58 % improvement in wound healing. This is associated with lower airborne pathogens (66.6 CFU/m³) and improved immune-inflammatory markers (↑IgG, ↓CRP/IL-6/TNF-α).</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100291"},"PeriodicalIF":2.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143851488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Ophthalmic Anesthesia Optimization with Predictive Embedding Models","authors":"Mingdi Zhang ,&nbsp;Wanqiu Jiao ,&nbsp;Kehui Tong ,&nbsp;Ping Zhang","doi":"10.1016/j.slast.2025.100290","DOIUrl":"10.1016/j.slast.2025.100290","url":null,"abstract":"<div><div>Ophthalmic anesthesia the crucial factors in success and safety of ophthalmic surgery, which involves the delicate aspects of pain control, sedation, and patient response. Advances in ophthalmic surgery cause a need for exact and individualized anesthetic procedures to maximize patient satisfaction and outcomes. This research investigates the machine learning (ML) and natural language processing (NLP) to personalize the practice of ophthalmic anesthesia. Text data includes preoperative assessments; drug history, procedure information, and discharge summary are preprocessed using the NLP approach, stop word removal, and lemmatization. Word2Vec technique is applied for feature extraction to represent clinical terms with vectors which carry semantic meaning, helping the model comprehend the text better. This research proposes a ML algorithm of Efficient Osprey Optimized Resilient Random Forest (EOO-RRF) model to forecast ideal anesthesia plans and patient results. Experimental results show that the EOO-RRF model is superior to traditional methods and achieves metrics such as MSE = 28.424, RMSE = 4.321, AUC=98.32% and R² = 0.956. The results indicate that combining NLP and ML in ophthalmic anesthesia leads to safer, more efficient, and personalized anesthetic management.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100290"},"PeriodicalIF":2.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143847446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}