Lancet Child & Adolescent Health最新文献

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Uncertainty in brain imaging after therapeutic hypothermia 治疗性低温后脑成像的不确定性
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-10-07 DOI: 10.1016/S2352-4642(25)00244-5
Tullio Ghi , Eugenio Mercuri , Luca A Ramenghi , Daniele De Luca
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引用次数: 0
Innovation in neonatology 新生儿科的创新
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-10-07 DOI: 10.1016/S2352-4642(25)00268-8
Thillagavathie Pillay , Karen Luyt , David Odd , Mike Trenell
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引用次数: 0
Innovation in neonatology – Authors' reply 新生儿科学的创新——作者的回答
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-10-07 DOI: 10.1016/S2352-4642(25)00267-6
Matheus van Rens , Robin van der Lee , Giovanni Barone , Fiammetta Piersigilli
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引用次数: 0
Correction to Lancet Child Adolesc Health 2025; 9: 766–75 《柳叶刀儿童青少年健康2025》修订版;9: 766 - 75
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-10-07 DOI: 10.1016/S2352-4642(25)00279-2
{"title":"Correction to Lancet Child Adolesc Health 2025; 9: 766–75","authors":"","doi":"10.1016/S2352-4642(25)00279-2","DOIUrl":"10.1016/S2352-4642(25)00279-2","url":null,"abstract":"","PeriodicalId":54238,"journal":{"name":"Lancet Child & Adolescent Health","volume":"9 11","pages":"Page e23"},"PeriodicalIF":15.5,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Training, values, and youth outcomes in adolescent and youth engagement in research 青少年和青少年参与研究的培训、价值观和青年成果
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-10-07 DOI: 10.1016/S2352-4642(25)00248-2
Clementine Jarrett , Alene Toulany , Colin Macarthur , Sarah Munce , UNITE research team
{"title":"Training, values, and youth outcomes in adolescent and youth engagement in research","authors":"Clementine Jarrett , Alene Toulany , Colin Macarthur , Sarah Munce , UNITE research team","doi":"10.1016/S2352-4642(25)00248-2","DOIUrl":"10.1016/S2352-4642(25)00248-2","url":null,"abstract":"","PeriodicalId":54238,"journal":{"name":"Lancet Child & Adolescent Health","volume":"9 11","pages":"Page e18"},"PeriodicalIF":15.5,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Children with disabilities are missing from global efforts to address violence 残疾儿童在全球解决暴力问题的努力中缺失
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-10-07 DOI: 10.1016/S2352-4642(25)00251-2
Emily Eldred , Anja Zinke-Allmang , Jinseo Kim , Alexandra Blackwell , Aya Fujita , Sabine van Tuyll van Serooskerken Rakotomalala , Tom Shakespeare , Hannah Kuper , Lucy Marie Richardson , Lena Morgon Banks , Karen Devries , Amiya Bhatia
{"title":"Children with disabilities are missing from global efforts to address violence","authors":"Emily Eldred , Anja Zinke-Allmang , Jinseo Kim , Alexandra Blackwell , Aya Fujita , Sabine van Tuyll van Serooskerken Rakotomalala , Tom Shakespeare , Hannah Kuper , Lucy Marie Richardson , Lena Morgon Banks , Karen Devries , Amiya Bhatia","doi":"10.1016/S2352-4642(25)00251-2","DOIUrl":"10.1016/S2352-4642(25)00251-2","url":null,"abstract":"","PeriodicalId":54238,"journal":{"name":"Lancet Child & Adolescent Health","volume":"9 11","pages":"Pages 757-759"},"PeriodicalIF":15.5,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Training, values, and youth outcomes in adolescent and youth engagement in research – Authors' reply 青少年和青年参与研究的培训、价值观和青年成果——作者的答复
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-10-07 DOI: 10.1016/S2352-4642(25)00250-0
Jason M Nagata , Zain Memon , David Imbago-Jácome , Shakira Choonara , Jonanne Talebloo , Molly O'Sullivan , Susan Sawyer , Sarah Baird
{"title":"Training, values, and youth outcomes in adolescent and youth engagement in research – Authors' reply","authors":"Jason M Nagata , Zain Memon , David Imbago-Jácome , Shakira Choonara , Jonanne Talebloo , Molly O'Sullivan , Susan Sawyer , Sarah Baird","doi":"10.1016/S2352-4642(25)00250-0","DOIUrl":"10.1016/S2352-4642(25)00250-0","url":null,"abstract":"","PeriodicalId":54238,"journal":{"name":"Lancet Child & Adolescent Health","volume":"9 11","pages":"Page e19"},"PeriodicalIF":15.5,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surviving and thriving after childhood cancer 从儿童癌症中幸存下来并茁壮成长。
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-09-25 DOI: 10.1016/S2352-4642(25)00280-9
The Lancet Child & Adolescent Health
{"title":"Surviving and thriving after childhood cancer","authors":"The Lancet Child & Adolescent Health","doi":"10.1016/S2352-4642(25)00280-9","DOIUrl":"10.1016/S2352-4642(25)00280-9","url":null,"abstract":"","PeriodicalId":54238,"journal":{"name":"Lancet Child & Adolescent Health","volume":"9 11","pages":"Page 753"},"PeriodicalIF":15.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term sequelae in survivors of high-risk neuroblastoma: the price of success 高风险神经母细胞瘤幸存者的长期后遗症:成功的代价。
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-09-25 DOI: 10.1016/S2352-4642(25)00274-3
Maria Antonietta De Ioris , Franco Locatelli
{"title":"Long-term sequelae in survivors of high-risk neuroblastoma: the price of success","authors":"Maria Antonietta De Ioris , Franco Locatelli","doi":"10.1016/S2352-4642(25)00274-3","DOIUrl":"10.1016/S2352-4642(25)00274-3","url":null,"abstract":"","PeriodicalId":54238,"journal":{"name":"Lancet Child & Adolescent Health","volume":"9 11","pages":"Pages 754-755"},"PeriodicalIF":15.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Late effects after high-risk neuroblastoma (LEAHRN): a multicentre, cross-sectional cohort study from the Children's Oncology Group 高风险神经母细胞瘤(LEAHRN)后的晚期效应:一项来自儿童肿瘤组的多中心横断面队列研究。
IF 15.5 1区 医学
Lancet Child & Adolescent Health Pub Date : 2025-09-25 DOI: 10.1016/S2352-4642(25)00241-X
Tara O Henderson MD , Jenna K Bardwell MPH , Pei-Chi Kao MPH , Paul C Nathan MD , Wendy Landier PhD , Sogol Mostoufi-Moab MD , Tara M Brinkman PhD , Fiona Schulte PhD , Julie R Park MD , Saro H Armenian DO , Arlene Naranjo PhD , Meera Subramaniam MD , Araz Marachellian MD , Sharon J Diskin PhD , Wendy B London PhD , Lisa R Diller MD
{"title":"Late effects after high-risk neuroblastoma (LEAHRN): a multicentre, cross-sectional cohort study from the Children's Oncology Group","authors":"Tara O Henderson MD , Jenna K Bardwell MPH , Pei-Chi Kao MPH , Paul C Nathan MD , Wendy Landier PhD , Sogol Mostoufi-Moab MD , Tara M Brinkman PhD , Fiona Schulte PhD , Julie R Park MD , Saro H Armenian DO , Arlene Naranjo PhD , Meera Subramaniam MD , Araz Marachellian MD , Sharon J Diskin PhD , Wendy B London PhD , Lisa R Diller MD","doi":"10.1016/S2352-4642(25)00241-X","DOIUrl":"10.1016/S2352-4642(25)00241-X","url":null,"abstract":"<div><h3>Background</h3><div>New treatment regimens have resulted in increasing numbers of children who survive high-risk neuroblastoma, but late effects of cancer therapy are not well studied. We aimed to explore treatment-related risk factors associated with late effects of modern therapies for high-risk neuroblastoma.</div></div><div><h3>Methods</h3><div>This multicentre, cross-sectional cohort study of survivors of high-risk neuroblastoma was done at 88 hospitals participating in the Children's Oncology Group (COG) in North America, Australia, and New Zealand. Eligible participants were aged 5–50 years at enrolment, were enrolled on ANBL00B1, were diagnosed with high-risk neuroblastoma on or after Jan 1, 2000, were alive at least 5 years after diagnosis, and had language skills in English, French, or Spanish. Individuals with active neuroblastoma relapse (cytotoxic chemotherapy in the previous 2 years) were ineligible. Participant evaluations included an audiogram, pulmonary function test, echocardiogram, and laboratory studies. Exposures were abstracted via chart review. Prevalence of a specific late effect was calculated as the number of participants with the late effect divided by the sample size with known data for that late effect. Multivariable logistic regression models examined associations between treatment-related risk factors versus hearing loss, growth failure, underweight, and restrictive lung disease.</div></div><div><h3>Findings</h3><div>Between June 5, 2017 and Sept 17, 2021, 375 eligible participants were enrolled from 890 potentially eligible individuals. Median age at high-risk neuroblastoma diagnosis was 2·5 years (range 0·2–15·8), median age at enrolment was 12·0 years (5·0–24·0), and median time from diagnosis to enrolment was 9·0 years (5·1–18·2). All participants received chemotherapy, 363 (97%) of 375 received at least one stem cell transplant and 231 (64%) of 363 patients with known data received anti-GD2 therapy. Moderate-to-severe hearing loss was identified in 236 (72%) of 327 participants. Growth failure was identified in 87 (24%) of 360 and underweight in 190 (51%) of 373. Pulmonary function tests revealed moderate-to-severe restrictive lung disease in 17 (8%) of 207 participants. Longer follow-up was associated with a higher prevalence of late effects. Compared with single stem-cell transplant, exposure to tandem stem-cell transplant was associated with increased risk of growth failure (odds ratio [OR] 3·4 [95% CI 1·6–7·2], p=0·0016] and moderate-to-severe restrictive lung disease (OR 4·5 [1·1–18·3]; p=0·033). Neither conditioning regimen exposure (carboplatin–etoposide–melphalan <em>vs</em> busulfan–melphalan) nor anti-GD2 therapy was associated with increased risk of hearing loss, underweight, growth failure, or restrictive lung disease.</div></div><div><h3>Interpretation</h3><div>Survivors of high-risk neuroblastoma treated with modern therapies demonstrated a substantial burden of late effects, providing cr","PeriodicalId":54238,"journal":{"name":"Lancet Child & Adolescent Health","volume":"9 11","pages":"Pages 776-786"},"PeriodicalIF":15.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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