Pulmonology最新文献

{"title":"Correspondence: Assessing the effectiveness of high-flow nasal cannula in treating acute respiratory failure in the elderly pulmonology.","authors":"Wei-Zhen Tang, Qin-Yu Cai, Tai-Hang Liu","doi":"10.1080/25310429.2024.2419719","DOIUrl":"https://doi.org/10.1080/25310429.2024.2419719","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2419719"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clustering patients with COVID-19 according to respiratory support requirements, and its impact on short- and long-term outcome (RECOVID study).","authors":"Rosario Menéndez, Raúl Méndez, Ana Latorre, Paula González-Jiménez, Germán Peces-Barba, María Molina-Molina, Pedro Pablo España, Estela García, Angélica Consuegra-Vanegas, Marta María García-Clemente, Carolina Panadero, Juan Marco Figueira-Gonçalves, David De la Rosa-Carrillo, Oriol Sibila, María Dolores Martínez-Pitarch, Nuria Toledo-Pons, Cecilia López-Ramírez, Wanda Almonte-Batista, Abigail Macías-Paredes, Mercedes Villamon, Marisol Domínguez-Álvarez, Eli Nancy Pérez-Rodas, Javier Lázaro, Sarai Quirós, Rosa Cordovilla, Irene Cano-Pumarega, Antoni Torres","doi":"10.1080/25310429.2024.2442175","DOIUrl":"10.1080/25310429.2024.2442175","url":null,"abstract":"<p><strong>Introduction: </strong>The Spanish Society of Pulmonology and Thoracic Surgery created a registry for hospitalised patients with COVID-19 and the different types of respiratory support used (RECOVID). Objectives. To describe the profile of hospitalised patients with COVID-19, comorbidities, respiratory support treatments and setting. In addition, we aimed to identify varying profiles of patients according to outcomes and the complexity of respiratory support needed.</p><p><strong>Methods: </strong>Multicentre, observational study in 49 Spanish hospitals. A protocol collected demographic data, comorbidities, respiratory support, treatment setting and 1-year follow-up. Patients were described using either frequency and percentages or median and interquartile range, as appropriate. A cluster analysis made it possible to identify different types of profile among the patients.</p><p><strong>Results: </strong>In total, 2148 of 2454 hospitalised patients (87.5%) received care in the conventional ward, whilst 126 in IRCU and 180 in ICU. In IRCU, 30% required high-flow nasal oxygen whilst 25%, non-invasive mechanical ventilation and 17%, mechanical ventilation. Four clusters of patients were identified. Two clusters were more likely to require IRCU/ICU admission, although primarily Cluster 2: Cluster (C) 1 consisted of patients without comorbidities and C2, those with comorbidities. Both presented higher inflammatory levels and lower lymphocyte count and SpO2/FiO2; however, C2 showed worse values. Two different clusters identified patients requiring less complex respiratory support. C3 presented higher comorbidities and elevated lymphocyte count, SpO2/FiO2 and low C-reactive protein (CRP). C4 included those without comorbidities except for arterial hypertension, lymphopenia and an intermediate CRP. In-hospital mortality and subsequent 1-year mortality were greater for C2 (28.6% and 7.1%) and C1 (11.1%, 8.3%) than for C4 (3.3%, 1.8%) and C3 (0%, 0%).</p><p><strong>Conclusions: </strong>The cluster analysis identified four clinical phenotypes requiring distinct types of respiratory support, with great differences present per characteristics and outcomes.</p>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2442175"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of anxiety and depression with prognosis in chronic obstructive pulmonary disease: A systematic review and meta-analysis.","authors":"Kefan Wu, Lifei Lu, Yubiao Chen, Jieqi Peng, Xiaohui Wu, Gaoying Tang, Ting Ma, Jing Cheng, Pixin Ran, Yumin Zhou","doi":"10.1080/25310429.2024.2438553","DOIUrl":"10.1080/25310429.2024.2438553","url":null,"abstract":"<p><p>The associations between anxiety, depression, and the prognosis of COPD remain uncertain. The present study aims to investigate the associations of anxiety and depression with 30-day readmission rates and acute exacerbations of COPD (AECOPD). Four databases were searched to identify relevant studies published before 13 March 2024. Studies that report on the impact of anxiety and depression on the prognosis of AECOPD were included. The pooled effect size and its 95% confidence interval (CI) were calculated using a random effects model. The primary outcomes were 30-day readmission and AECOPD within the first year after discharge in COPD patients. Of the 5,955 studies screened, 14 studies were included in the analysis. Patients with anxiety had a higher risk of AECOPD within the first year after discharge compared to those without anxiety (HR: 2.10, 95% CI: 1.28-3.45, <i>p</i> = 0.003). Patients with depression also had a higher risk of AECOPD within the first year after discharge (HR: 1.36, 95% CI: 1.10-1.69, <i>p</i> = 0.004). Similar results were observed in the associations of anxiety and depression with 30-day readmission. Our results suggested that anxiety and depression were associated with an increased risk of 30-day readmission and AECOPD in patients with COPD.</p>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2438553"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142820090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endobronchial ultrasound-guided cryobiopsy of a rare epicardial tumour.","authors":"Toshiyuki Nakai, Atsushi Miyamoto, Mana Ogawa, Akimasa Morisaki, Nobuhiro Izumi, Sayaka Tanaka","doi":"10.1080/25310429.2025.2458368","DOIUrl":"https://doi.org/10.1080/25310429.2025.2458368","url":null,"abstract":"<p><strong>Background: </strong>Cardiac tumors are rare, and a nonsurgical diagnosis is preferred for determining appropriate treatment strategies.</p><p><strong>Research question: </strong>Can Endobronchial ultrasound-guided cryobiopsy (EBUS-cryo) be useful for diagnosing cardiac tumors?</p><p><strong>Study design and methods: </strong>This paper presents a case report on the successful diagnosis of a rare cardiac tumor using EBUS-cryo. A 60-year-old woman was referred to our hospital after echocardiography revealed an epicardial tumor compressing the bilateral atria. Computed tomography revealed a 90-mm cardiac tumor adjacent to the tracheal bifurcation compressing the surrounding large vessels. Endobronchial ultrasound-guided cryobiopsy (EBUS-cryo) was performed, and a histological diagnosis of schwannoma, a type of peripheral nerve sheath tumor (PNST), was made without severe complications. Surgical resection was performed, and the tumor was found to originate from the pericardium on the left atrial wall.</p><p><strong>Results: </strong>The surgical specimens contained small areas of perineurioma in addition to schwannoma, leading to the final diagnosis of extremely rare hybrid PNST.</p><p><strong>Conclusion: </strong>EBUS-cryo can be one of useful biopsy techniques for diagnosing cardiac tumors.</p>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2458368"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological effects of nasal high flow therapy during exercise in patients with chronic obstructive pulmonary disease: A crossover randomised controlled trial.","authors":"Tristan Bonnevie, Francis-Edouard Gravier, Pauline Smondack, Emeline Fresnel, Isabelle Rivals, Helena Brunel, Yann Combret, Clément Médrinal, Guillaume Prieur, Fairuz Boujibar, Thomas Similowski, Jean-François Muir, Antoine Cuvelier, Maxime Patout","doi":"10.1080/25310429.2025.2466922","DOIUrl":"https://doi.org/10.1080/25310429.2025.2466922","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2466922"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The rise of old villains: the vaccination downfall worldwide.","authors":"Matheus Negri Boschiero, Camila Vantini Capasso Palamim, Tais Mendes Camargo, Fernando Augusto Lima Marson","doi":"10.1080/25310429.2025.2466924","DOIUrl":"https://doi.org/10.1080/25310429.2025.2466924","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2466924"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-dose inhaled NO for the prevention of nosocomial pneumonia after cardiac surgery under cardiopulmonary bypass: A proof-of-concept prospective randomised study.","authors":"Tatiana P Kalashnikova, Nikolay O Kamenshchikov, Yulia A Arsenyeva, Yuri K Podoksenov, Igor V Kravchenko, Maxim S Kozulin, Mark A Tyo, Elena A Churilina, Elena B Kim, Yulia S Svirko, Boris N Kozlov, Alla A Boshchenko","doi":"10.1080/25310429.2025.2471706","DOIUrl":"https://doi.org/10.1080/25310429.2025.2471706","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the safety and potential efficacy of high-dose inhaled nitric oxide therapy for the prevention of postoperative pneumonia in cardiac surgery patients.</p><p><strong>Methods: </strong>A prospective randomised controlled pilot study included 74 patients with moderate risk of postoperative pneumonia after elective cardiac surgery under cardiopulmonary bypass. Patients were randomised into two groups. The main group (NO-group) (<i>n</i> = 37) received inhaled nitric oxide at a dose of 200 ppm for 30 minutes 2 times a day for 5 days or until pneumonia developed. The control group received conventional postoperative care (<i>n</i> = 37). The primary endpoint was the incidence of postoperative pneumonia during in-hospital stay.</p><p><strong>Results: </strong>Preventive nitric oxide inhalations were associated with a reduced incidence of postoperative nosocomial pneumonia (2 (5.4%) cases in the main group (NO-group) vs. 9 (24.3%) cases in the control group, <i>p</i> = 0.046; OR = 0.178, 95% CI = 0.036-0.89)). There was no decrease in either peak expiratory flow, or peak inspiratory flow in comparison with the preoperative values in the NO-group. Inhaled nitric oxide therapy is safe. It did not lead to an increase in the incidence of acute kidney injury.</p><p><strong>Conclusions: </strong>High-dose inhaled nitric oxide therapy is safe and effective for the prevention of postoperative nosocomial pneumonia in cardiac surgery.</p>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2471706"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life associated with breathlessness in the multinational Burden of Obstructive Lung Disease (BOLD) study: A cross-sectional analysis.","authors":"Alexander Müller, Emiel F M Wouters, Peter Burney, James Potts, Joao Cardoso, Mohammed Al Ghobain, Michael Studnicka, Daniel Obaseki, Asma Elsony, Kevin Mortimer, David Mannino, Rain Jõgi, Rana Ahmed, Asaad Nafees, Maria Fatima Rodrigues, Cristina Bárbara, Rune Nielsen, Thorarinn Gíslason, Hamid Hacene Cherkaski, Karima El Rhazi, Christer Janson, Mahesh Padukudru Anand, Sanjay Juvekar, Herminia Brites Dias, Frits M E Franssen, Dhiraj Agarwal, Sylvia Hartl, Terence Seemungal, Stefanni Nonna Paraguas, Imed Harrabi, Meriam Denguezli, Abdul Rashid, Gregory Erhabor, Mohammed El Biaze, Parvaiz Koul, Daisy J A Janssen, André F S Amaral","doi":"10.1080/25310429.2025.2470566","DOIUrl":"https://doi.org/10.1080/25310429.2025.2470566","url":null,"abstract":"<p><strong>Introduction: </strong>Evidence of an association between breathlessness and quality of life from population-based studies is limited. We aimed to investigate the association of both physical and mental quality of life with breathlessness across several low-, middle- and high-income countries.</p><p><strong>Methods: </strong>We analysed data from 19 714 adults (31 sites, 25 countries) from the Burden of Obstructive Lung Disease (BOLD) study. We measured both mental and physical quality of life components using the SF-12 questionnaire, and defined breathlessness as grade ≥2 on the modified Medical Research Council scale. We used multivariable linear regression to assess the association of each quality-of-life component with breathlessness. We pooled site-specific estimates using random-effects meta-analysis.</p><p><strong>Results: </strong>Both physical and mental component scores were lower in participants with breathlessness compared to those without. This association was stronger for the physical component (coefficient = -7.59; 95%CI -8.60, -6.58; I² = 78.5%) than for the mental component (coefficient = -3.50; 95%CI -4.36, -2.63; I² = 71.4%). The association between physical component and breathlessness was stronger in high-income countries (coefficient = -8.82; 95%CI -10.15, -7.50). Heterogeneity across sites was partly explained by sex and tobacco smoking.</p><p><strong>Conclusion: </strong>Quality of life is worse in people with breathlessness, but this association varies widely across the world.</p>","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2470566"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weaning from tracheostomy: Trend of decannulation rate over two decades in a respiratory rehabilitation centre.","authors":"Matteo Vigna, Cinzia Lastoria, Annalisa Carlucci, Serena Cirio, Matteo Prazzoli, Piero Ceriana","doi":"10.1080/25310429.2024.2411814","DOIUrl":"https://doi.org/10.1080/25310429.2024.2411814","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2411814"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complete response to mTOR inhibitor following JAKi failure in severe pulmonary sarcoidosis: Authors' reply.","authors":"Raphaël Hindré, Valérie Besnard, Fatma Kort, Hilario Nunes, Dominique Valeyre, Florence Jeny","doi":"10.1080/25310429.2024.2422210","DOIUrl":"https://doi.org/10.1080/25310429.2024.2422210","url":null,"abstract":"","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2422210"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}