Pulmonology最新文献_第7页

Why not a 95-95-95 strategy for influenza by 2030? 为什么不在2030年前制定一项针对流感的95-95-95战略呢？

IF 10.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2025-04-30 DOI: 10.1080/25310429.2025.2491896

Filipe Froes, George Kassianos

引用次数: 0

The clinical meaning of the UIP pattern in fibrotic hypersensitivity pneumonitis on cryobiopsy: A multicentre retrospective study. 纤维化超敏性肺炎低温活检UIP模式的临床意义：一项多中心回顾性研究。

IF 10.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2024-11-12 DOI: 10.1080/25310429.2024.2425503

Simone Petrarulo, Claudia Ravaglia, Sissel Kronborg White, Line Bille Madsen, Frederik Lex, Alessandra Dubini, Elisabetta Fabbri, Elisabeth Bendstrup, Paolo Spagnolo, Sara Piciucchi, Venerino Poletti

{"title":"The clinical meaning of the UIP pattern in fibrotic hypersensitivity pneumonitis on cryobiopsy: A multicentre retrospective study.","authors":"Simone Petrarulo, Claudia Ravaglia, Sissel Kronborg White, Line Bille Madsen, Frederik Lex, Alessandra Dubini, Elisabetta Fabbri, Elisabeth Bendstrup, Paolo Spagnolo, Sara Piciucchi, Venerino Poletti","doi":"10.1080/25310429.2024.2425503","DOIUrl":"10.1080/25310429.2024.2425503","url":null,"abstract":"Fibrotic hypersensitivity pneumonitis (f-HP) is an interstitial lung disease in which various antigens in susceptible individuals may play a pathogenetic role. This study evaluates the role of transbronchial lung cryobiopsy (TBLC) and bronchoalveolar lavage (BAL) in identifying a UIP-like pattern and its association with fibrosis progression. We conducted a multicentre retrospective cohort study of patients diagnosed with f-HP who underwent BAL and TBLC between 2011 and 2023. A UIP-like pattern was defined by the presence of (A) patchy fibrosis and fibroblastic foci or (B) honeycombing ± (A). We investigated BAL's role in predicting UIP-like patterns within a clinical-radiological-serological framework, examining disease progression in these patients using spirometry and mortality data. A total of 195 patients were enrolled, 59 (30%) of whom exhibited a UIP-like pattern. These patients showed greater lung function decline, lower BAL lymphocytosis (14.4% vs. 37.4%, p < 0.001), higher nintedanib prescription (35% vs. 14%, p < 0.001), and higher 10-year mortality (HR 2.8, 95% CI 1.3-5.8, p = 0.004). f-HP patients with a UIP-like pattern exhibit worse clinical outcomes and higher mortality. In cases of low BAL lymphocytosis with a high pre-test clinical suspicion of f-HP, lung biopsy may not be necessary as it increases the likelihood of identifying a UIP-like pattern.","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2425503"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How should we determine the presence of functional impairment in people with COPD? 我们应该如何确定COPD患者是否存在功能损害？

IF 10.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2025-06-27 DOI: 10.1080/25310429.2025.2522015

Ana Machado, Chris Burtin, Alda Marques

引用次数: 0

Bronchodilators in bronchiectasis: A story difficult to understand. 支气管扩张中的支气管扩张剂：一个难以理解的故事。

IF 10.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2025-05-23 DOI: 10.1080/25310429.2025.2497179

Grace Oscullo, Amina Bekki, Miguel Ángel Martínez-García

引用次数: 0

Vaccination in post-tuberculosis lung disease management: A review of the evidence. 结核病后肺部疾病管理中的疫苗接种：证据综述。

IF 10.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2024-10-24 DOI: 10.1016/j.pulmoe.2023.07.002

M J Nasiri, D R Silva, F Rommasi, M M Zahmatkesh, Z Tajabadi, F Khelghati, T Sarmastzadeh, R Centis, L D'Ambrosio, S Bombarda, M P Dalcolmo, T Galvão, F C de Queiroz Mello, M F Rabahi, E Pontali, I Solovic, M Tadolini, L Marconi, S Tiberi, M van den Boom, G Sotgiu, G B Migliori

{"title":"Vaccination in post-tuberculosis lung disease management: A review of the evidence.","authors":"M J Nasiri, D R Silva, F Rommasi, M M Zahmatkesh, Z Tajabadi, F Khelghati, T Sarmastzadeh, R Centis, L D'Ambrosio, S Bombarda, M P Dalcolmo, T Galvão, F C de Queiroz Mello, M F Rabahi, E Pontali, I Solovic, M Tadolini, L Marconi, S Tiberi, M van den Boom, G Sotgiu, G B Migliori","doi":"10.1016/j.pulmoe.2023.07.002","DOIUrl":"10.1016/j.pulmoe.2023.07.002","url":null,"abstract":"Introduction and objectives: Post-tuberculosis lung disease (PTLD), as other chronic respiratory disorders, may have infectious complications; some of them can be prevented with vaccinations. So far, no document has discussed the potential role of vaccination in PTLD. Therefore, the objective of this review was to describe vaccination recommendations to prevent infections potentially capable of complicating PTLD.Materials and methods: A non-systematic review of the literature was conducted. The following keywords were used: tuberculosis, vaccination, vaccines and PTLD. PubMed/MEDLINE and Embase were used as the search engine, focusing on English-language literature only.Results: We identified 9 vaccines potentially useful in PTLD. Influenza, pneumococcal and anti-COVID-19 vaccinations should be recommended. Patients with PTLD can also benefit from vaccination against shingles. Vaccination against pertussis is mainly relevant during childhood. Diphtheria, tetanus and measles vaccination are recommended for general population and should be considered in patients with PTLD not previously vaccinated. Tdap (Tetanus, diphtheria, and pertussis) booster should be repeated in every adult every ten years. Vaccination against BCG retains its importance during early childhood in countries where TB is endemic.Conclusions: Vaccination deserves to be considered among the strategies to prevent and/or mitigate PTLD complications. Further evidence is necessary to better understand which vaccines have the greatest impact and cost-benefit.","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":" ","pages":"2416801"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10172832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Financial burden of productivity loss in severe asthma and impact of biologic therapy. 严重哮喘生产力损失的经济负担和生物治疗的影响。

IF 10.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2025-07-21 DOI: 10.1080/25310429.2025.2532973

Kjell Erik Julius Håkansson, Rikke Ibsen, Niels Steen Krogh, Marianne Baastrup Soendergaard, Susanne Hansen, Anne-Sofie Bjerrum, Anna von Bülow, Ole Hilberg, Anders Løkke, Barbara Bonnesen Bertelsen, Claus Rikard Johnsen, Sofie Lock Johansson, Lycely Dongo, Maria Bisgaard Borup, Roxana Vijdea, Linda Makowska Rasmussen, Johannes Martin Schmid, Charlotte Suppli Ulrik, Celeste Porsbjerg

{"title":"Financial burden of productivity loss in severe asthma and impact of biologic therapy.","authors":"Kjell Erik Julius Håkansson, Rikke Ibsen, Niels Steen Krogh, Marianne Baastrup Soendergaard, Susanne Hansen, Anne-Sofie Bjerrum, Anna von Bülow, Ole Hilberg, Anders Løkke, Barbara Bonnesen Bertelsen, Claus Rikard Johnsen, Sofie Lock Johansson, Lycely Dongo, Maria Bisgaard Borup, Roxana Vijdea, Linda Makowska Rasmussen, Johannes Martin Schmid, Charlotte Suppli Ulrik, Celeste Porsbjerg","doi":"10.1080/25310429.2025.2532973","DOIUrl":"https://doi.org/10.1080/25310429.2025.2532973","url":null,"abstract":"Background: Severe asthma leads to considerable productivity loss; however, patients' financial impact and the potential reversal through biologic therapy remain unexplored.Research question: What is the financial burden of productivity loss among employed individuals with severe asthma, and does it change during biologic therapy?Study design and methods: Employed individuals from the Danish Severe Asthma Register (2016-2022) were included. Salary data were sourced from national registries, while productivity loss was measured using the Workplace Productivity and Activity Impairment (WPAI) Questionnaire at baseline and after a minimum of four months of biologic therapy.Results: A total of 132 employed individuals (mean age 47.9 years, 39% female, mean annual salary € 74,646) were included. Before biologic therapy, productivity impairment was 39.1%. presenteeism and absenteeism rates were 35.8% and 11.3%, respectively, equating to annual productivity losses of € 28,880 per individual.On treatment, overall impairment was 17.6%, with significant reductions in both presenteeism and absenteeism, corresponding to annual loss reductions of € 16,506 per individual.Interpretation: The financial burden of productivity loss in severe asthma is substantial, primarily due to presenteeism. Biologic therapy significantly enhances productivity, suggesting that much of the individual financial burden can be reversed.","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2532973"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe acute asthma exacerbations under biological agents: A new therapeutic paradigm? 生物制剂治疗严重急性哮喘：一种新的治疗模式？

IF 6.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2025-10-09 DOI: 10.1080/25310429.2025.2571016

Diogo Antunes, Rita Oliveira, Marisa Paulino, Fernanda Paula Santos, Filipe Froes

引用次数: 0

Associations of pre-COPD indicators with lung function decline and their longitudinal transitions. copd前期指标与肺功能下降的关系及其纵向转变。

IF 10.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2025-05-12 DOI: 10.1080/25310429.2025.2486881

Jing Fan, Shu Cong, Yang Zhang, Xiao Jiang, Ning Wang, Liwen Fang, Yahong Chen

{"title":"Associations of pre-COPD indicators with lung function decline and their longitudinal transitions.","authors":"Jing Fan, Shu Cong, Yang Zhang, Xiao Jiang, Ning Wang, Liwen Fang, Yahong Chen","doi":"10.1080/25310429.2025.2486881","DOIUrl":"https://doi.org/10.1080/25310429.2025.2486881","url":null,"abstract":"Background: Pre-chronic obstructive pulmonary disease (COPD) indicators are associated with COPD development, but their associations with lung function decline in persons without COPD and their longitudinal transitions remain uncertain.Methods: In this prospective cohort study, 3526 subjects without COPD from the 2014-2015 national COPD surveillance in China were investigated for a second time during 2018-2020. Four potential pre-COPD indicators at baseline were chronic bronchitis, preserved ratio impaired spirometry (PRISm), low peak expiratory flow (PEF), and spirometric small airway dysfunction (sSAD). To include the incident COPD subjects in the lung function decline analysis for consistent indicators, forced expiratory volume in 1 s (FEV1) <80% predicted was used instead of PRISm. Lung function outcomes were the declines in post-bronchodilator FEV1, forced vital capacity (FVC), and FEV1/FVC.Results: Subjects with initial chronic bronchitis had faster declines in FEV1 and FVC compared with those without initial chronic bronchitis among smokers. Consistent chronic bronchitis was associated with faster declines in FEV1 and FVC among non-smokers. Consistent sSAD was associated with faster declines in FEV1/FVC among smokers and non-smokers. Consistent FEV1 <80% predicted and consistent low PEF were associated with a faster decline in FEV1/FVC among smokers. Incident COPD developed from sSAD in almost half of the cases.Conclusions: Initial chronic bronchitis and consistent FEV1 <80% predicted, sSAD, and low PEF are associated with excessive lung function decline among smokers, while consistent chronic bronchitis and sSAD are associated with excessive lung function decline among non-smokers. Initial sSAD accounts for a larger proportion of incident COPD than initial chronic bronchitis, PRISm, and low PEF.","PeriodicalId":54237,"journal":{"name":"Pulmonology","volume":"31 1","pages":"2486881"},"PeriodicalIF":10.4,"publicationDate":"2025-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correspondence: Synergistic effect of public health and social work in the pre-detection of tuberculous pleurisy. 通讯：公共卫生和社会工作在结核性胸膜炎预诊中的协同作用。

IF 10.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2024-10-30 DOI: 10.1080/25310429.2024.2411801

Xinkun Shen, Qiang Zhou, Qian Guo

引用次数: 0

Pulmonary metastasis of dermatofibrosarcoma protuberans. 隆突性皮肤纤维肉瘤的肺转移。

IF 10.4 2区医学

Pulmonology Pub Date : 2025-12-31 Epub Date: 2025-05-29 DOI: 10.1080/25310429.2025.2498280

Qinghua Cao, Cuiping Zhang, Lixia Li, Haifei Li, Xiang Li, Fan Wanfeng

引用次数: 0