International Journal of Health and Allied Sciences最新文献_第4页

Sigma-Metric Analysis to Evaluate Quality Management of Analytical Processes Using RCA and QGI in a Clinical Biochemistry Laboratory, South India 西格玛-度量分析评价使用RCA和QGI在印度南部临床生物化学实验室的分析过程的质量管理

International Journal of Health and Allied Sciences Pub Date : 2023-06-13 DOI: 10.55691/2278-344x.1035

S. Nilakantam, Kusuma Kasapura Shivashankar, Akila Prashant, Melanahalli Dayananda, Suma M. Nataraj, Namratha G Dayananda

{"title":"Sigma-Metric Analysis to Evaluate Quality Management of Analytical Processes Using RCA and QGI in a Clinical Biochemistry Laboratory, South India","authors":"S. Nilakantam, Kusuma Kasapura Shivashankar, Akila Prashant, Melanahalli Dayananda, Suma M. Nataraj, Namratha G Dayananda","doi":"10.55691/2278-344x.1035","DOIUrl":"https://doi.org/10.55691/2278-344x.1035","url":null,"abstract":"Introduction : This study aimed to identify laboratory errors at the earliest through Sigma-metric analysis and to evaluate quality management of analytical processes. Methods : Sigma-metrics and Quality Goal Index (QGI) were calculated by harvesting the IQC and EQC data of an accredited laboratory for 31 biochemical parameters run on Roche Cobas6000 and e411. Those with Sigma (cid:1) 2 were further analysed by applying the various Westgard rules, as suggested Results : Nearly 13 chemistry analytes showed world-class performance with Sigma > 6 and most of the immunoassay parameters showed marginal performance with sigma > 2 (cid:1) 6. Sodium, Chloride, Total T4, Beta-HCG and TSH were found to have Sigma < 2 indicating unacceptable performance. A signi ﬁ cant improvement was observed in the Sigma-metrics analysis after performing the root cause analysis Conclusion : Sigma-metric analyses the quality management of various analytical processes in biochemistry. The poor assay performance will be picked up by the Root cause analysis and Quality Goal Indices calculation. With the help of RCA and QGI, we plan to increase the resource management by decreasing the frequency of QC runs.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73996986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment burden, not health risk attitude associated with adherence in patients with mental illness in South India 南印度精神疾病患者治疗负担而非健康风险态度与依从性相关

International Journal of Health and Allied Sciences Pub Date : 2023-06-13 DOI: 10.55691/2278-344x.1033

D. Ram, Neethu Benny, Shruthy Kv

{"title":"Treatment burden, not health risk attitude associated with adherence in patients with mental illness in South India","authors":"D. Ram, Neethu Benny, Shruthy Kv","doi":"10.55691/2278-344x.1033","DOIUrl":"https://doi.org/10.55691/2278-344x.1033","url":null,"abstract":"Background : Attitude towards health risks and treatment burden may mediate treatment adherence in therapeutic care. There is a paucity of study examining the levels and relationships of these variables in patients with mental illness. Objective : This study was conducted to know the relationships of health risk attitude & treatment burden and medication adherence in patients with mental illness. Settings and design : Cross-sectional, Hospital-based study. Methods and material : One hundred seventy consecutive participants in remission of mental illness were recruited. The patient ' s details were assessed with Sociodemographic proforma while attitude towards health risk was assessed with Health-Risk Attitude Scale (HRAS). To evaluate the burden of treatment, the Treatment Burden Questionnaire (TBQ) was used while medication adherence was rated with the Medication Adherence Rating Scale (MARS). Statistical analysis used : Descriptive statistics, Kruskal e Wallis H, Linear regression analysis. Results : Mean score on MARS was 4.9 (SD ± 1.7) while HRAS and TBQ were 62.2 (SD ± 8.6) and 44.2 (SD ± 23). On linear regression analysis scores of TBQ were statistically signi ﬁ cant positively linked to HRAS score (R 2 ¼ .35, df ¼ 1, F ¼ 94.2, p ¼ 0.001), While Scores on MARS were statistically signi ﬁ cant negatively linked TBQ and HRAS score (R 2 ¼ .53, df ¼ 2, F ¼ 97.1, p ¼ 001). Conclusions : Health risk aversion and treatment burden may upraise in mentally ill, and linked to poor medication adherence.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"201 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76981405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect Of Fenugreek And Curry Leaves Powder On Dyslipidemia- A Randomized Controlled Pilot Study 胡芦巴和咖喱叶粉对血脂异常的影响——一项随机对照的初步研究

International Journal of Health and Allied Sciences Pub Date : 2023-06-13 DOI: 10.55691/2278-344x.1031

Syeda Farha S, Shivani Agarwal, Vanitha Reddy P

{"title":"Effect Of Fenugreek And Curry Leaves Powder On Dyslipidemia- A Randomized Controlled Pilot Study","authors":"Syeda Farha S, Shivani Agarwal, Vanitha Reddy P","doi":"10.55691/2278-344x.1031","DOIUrl":"https://doi.org/10.55691/2278-344x.1031","url":null,"abstract":"Background: Dyslipidemias, a disorder of lipid metabolism, is widely established as an independent major and modifiable risk factor of cardiovascular disease (CVD). The conditions are common worldwide and a leading cause of death in India, and has even riven the age bar swaying in young people too. The significant effect of an increase in dyslipidemias depends on diabetes and hypertension. Nutraceuticals, derived from food sources serve as an alternative therapy for the management of dyslipidemia. India is home to multitudinous medicinal plants, of which many remain underutilized. Murraya Koenigii (curry leaf) and Trigonella foenum-graecum (fenugreek leaves) are well-proven as good sources of nutraceutical and functional foods. Objectives: To study the effect of fenugreek and curry leaves powder on dyslipidemia and also the dietary habits of dyslipidemic subjects. Materials and methods: 31 subjects aged between 40 and 70 years were recruited based on inclusion and exclusion criteria, and grouped into group 1(hypertensive with dyslipidemia), group 2 (diabetic with dyslipidemia), and group 3 (only dyslipidemia) supplemented with the mixture of fenugreek and curry leaf powder for 3 months. Results: Reduction in total cholesterol and triglyceride levels were observed in group 2 (DM þ DLP) and group 1 (HTN þ DLP) i.e 221.2 ± 29 and 193 ± 72.4 respectively. The HDL levels increased in all three groups. Reduced VLDL and FBS levels were observed in all three groups. Conclusion: Our findings showed that fenugreek and curry leaf powder supplementation, as a phenolic-rich herb can be effective in the reduction of some lipid profiles in dyslipidemic patients suggesting their potential neutraceutical role in treating CVD.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"359 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76392201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19: An impetus to reform paediatrics curriculum for undergraduate medical students in Iraq 2019冠状病毒病:推动伊拉克医科本科学生儿科课程改革

International Journal of Health and Allied Sciences Pub Date : 2023-06-13 DOI: 10.55691/2278-344x.1037

M. Al-Mendalawi

引用次数: 0

Bed utilization pattern of intensive care units affiliated to Ministry of Health: a national study in Egypt prior to the COVID-19 pandemic 卫生部附属重症监护病房床位利用模式:2019冠状病毒病大流行前埃及的一项全国性研究

International Journal of Health and Allied Sciences Pub Date : 2023-03-28 DOI: 10.55691/2278-344x.1021

A. El-Gilany, Abeer El Ashry, M. Khafagy, Noha El Adawi, M. Bahgat

引用次数: 0

Research Article A new Informatics Framework for Evaluating the Codon Usage Metrics, Evolutionary Models and Phylogeographic reconstruction of Tomato yellow leaf curl virus (TYLCV) in different regions of Asian countries 亚洲不同地区番茄黄卷叶病毒(TYLCV)密码子使用指标、进化模型和系统地理重构的新信息学框架

International Journal of Health and Allied Sciences Pub Date : 2023-03-28 DOI: 10.55691/2278-344x.1022

Mamathashree Mn, Kuralyanapalya Putta, Honnappa Suresh, Sharanagouda S Patil, Uma Bharathi Indrabalan, Mallikarjun S Beelagi, Sushma Pradeep, Krishnamoorthy Paramanandham, Siju Susan Jacob, Chandrashekar Srinivasa, Shiva Prasad Kollur, Raghu Ram Achar, Ashwini Prasad, Shashanka K Prasad, Chandan Shivamallu

{"title":"Research Article A new Informatics Framework for Evaluating the Codon Usage Metrics, Evolutionary Models and Phylogeographic reconstruction of Tomato yellow leaf curl virus (TYLCV) in different regions of Asian countries","authors":"Mamathashree Mn, Kuralyanapalya Putta, Honnappa Suresh, Sharanagouda S Patil, Uma Bharathi Indrabalan, Mallikarjun S Beelagi, Sushma Pradeep, Krishnamoorthy Paramanandham, Siju Susan Jacob, Chandrashekar Srinivasa, Shiva Prasad Kollur, Raghu Ram Achar, Ashwini Prasad, Shashanka K Prasad, Chandan Shivamallu","doi":"10.55691/2278-344x.1022","DOIUrl":"https://doi.org/10.55691/2278-344x.1022","url":null,"abstract":": Tomato yellow leaf curl virus (TYLCV) is a major devastating viral disease, majorly affecting the tomato production globally. The disease is majorly transmitted by the Whitefly. The Begomovirus (TYLCV) having a six major protein coding genes, among them the C1/AC1 is evidently associated with viral replication. Owing to immense role of C1/AC1 gene, the present study is an initial effort to elucidate the factors shaping the codon usage bias and evolutionary pattern of TYLCV-C1/AC1 gene in five major Asian countries. Based on publically available nucleotide sequence data the Codon usage pattern, Evolutionary and Phylogeographic reconstruction was carried out. The study revealed the presence of significant variation between the codon bias indices in all the selected regions. Implying that the codon usage pattern indices (eNC, CAI, RCDI, GRAVY, Aromo) are seriously affected by selection and mutational pressure, taking a supremacy in shaping the codon usage bias of viral gene. Further, the tMRCA age was 1853, 1939, 1855, 1944, 1828 for China, India, Iran, Oman and South Korea, respectively for TYLCV-C1/AC1 gene. The integrated analysis of Codon usage bias, Evolutionary rate and Phylogeography analysis in viruses signifies the positive role of selection and mutational pressure among the selected regions for TYLCV (C1/AC1) gene.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135723015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In silico examination of peptides containing selenium and ebselen Backbone To Assess Their Tumoricidal Potential 含硒和乙硒主链肽的计算机检测以评估其杀肿瘤潜能

International Journal of Health and Allied Sciences Pub Date : 2023-03-28 DOI: 10.55691/2278-344x.1029

Smitha S Bhat, Sushma Pradeep, Greeshma Jadhav, Devananda Devegowda, Sarana Rose Sommano, Chandan Shivamallu, Shiva Prasad Kollur, Shashanka K Prasad

{"title":"In silico examination of peptides containing selenium and ebselen Backbone To Assess Their Tumoricidal Potential","authors":"Smitha S Bhat, Sushma Pradeep, Greeshma Jadhav, Devananda Devegowda, Sarana Rose Sommano, Chandan Shivamallu, Shiva Prasad Kollur, Shashanka K Prasad","doi":"10.55691/2278-344x.1029","DOIUrl":"https://doi.org/10.55691/2278-344x.1029","url":null,"abstract":"Introduction: Cancer has been one of the highest causes of morbidity and mortality in the world for decades. Owing to improved therapeutics along with detection, breast cancer mortality has been slowly reducing. The incidence of breast cancer, on the other hand, has increased gradually. More than 100 types of cancer have been identified with a wide range of treatment protocols comprising of chemotherapy, radiation therapy, hormone therapy, etc. In an attempt to curb the serious deleterious effects caused by the chemotherapeutic drugs, numerous peptide molecules are currently popular as alternatives to the standard chemotherapeutic drugs. Methods: In this study, we have carried out in silico investigations to ascertain the anti-proliferative potential of novel peptides based on selenium and ebselen, i.e. Eb-Trp-Asp, 13, Eb-Trp-Glu, 14, and Eb-Trp-Lys, 15. Analysis of protein-ligand interactions, resulting in protein-ligand complex formation, has been carried out using the AutoDockVina in PyRx aided molecular docking technique, which may be an essential indication of druggability of the test peptides. Results: The molecular docking results revealed that the screened ligands had extraordinarily strong binding interactions and affinity for the target. Conclusion: Findings suggested that novel peptide molecule Eb-Trp-Glu, 14 may be a potent anticancer agent.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"217 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135628721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Elevated serum Homocysteine levels a possible non-invasive diagnostic biomarker in patients with Non-alcoholic fatty liver disease 血清同型半胱氨酸水平升高是非酒精性脂肪肝患者可能的非侵入性诊断生物标志物

International Journal of Health and Allied Sciences Pub Date : 2023-03-28 DOI: 10.55691/2278-344x.1025

Panchami H.K., K. M, Varsha D. Shiragannanavar, Nirmala G. Sannappagowda, Shreyas H. Karunakara, Lakshana D. Puttahanumantharayappa, Kusuma K.S., Swetha N.K., Sumalatha. M.N, Prasanna K. Santhekadur

引用次数: 0

Antioxidant effect of Morus indica L against paraquat-induced oxidative stress in Drosophila melanogaster 桑对百草枯诱导的黑腹果蝇氧化应激的抗氧化作用

International Journal of Health and Allied Sciences Pub Date : 2023-03-28 DOI: 10.55691/2278-344x.1026

M. S, Syeda Farha S, M. Reddy, S. Cs, S. A

引用次数: 0

Perceptual and Acoustical assessment of voice in children with cleft lip and palate 唇腭裂儿童声音的知觉和声学评价

International Journal of Health and Allied Sciences Pub Date : 2023-03-28 DOI: 10.55691/2278-344x.1027

Indu Thammaiah, Meenakshi S, R. N, R. Ramu

引用次数: 0