International Journal of Health and Allied Sciences最新文献

{"title":"Watermelon seed extract inhibits protein aggregation and formation of advanced glycation end-products","authors":"Faiyaz Ahmed, Satish A","doi":"10.55691/2278-344x.1048","DOIUrl":"https://doi.org/10.55691/2278-344x.1048","url":null,"abstract":"BACKGROUND: Glycation of proteins is a key element in the onset of diabetes consequences. The potential of medicinal plants to inhibit the progression of glycation complications provides a significant opportunity as an alternative therapy. METHODS: The effect of watermelon seed extract (WMSE) on antioxidant capacity was assessed based on radical scavenging activity and metal chelation activity. Further the inhibition of Advanced glycation end-products (AGEs) formation was assessed by using different sources of amine (haemoglobin, bovine serum albumin, G.K peptide) and sugar sources (δ-gluconolactone, methylglyoxal, ribose). Aminoguanidine (AG) used as standard drug. RESULTS: Due to the presence of various phytochemicals that could disrupt the chain of events and prevent the development of AGEs, WMSE demonstrated its potential inhibitory effects at every step of protein glycation. A key part of this response is the scavenging of free radicals produced by glycation. CONCLUSION: The WMSE may aid to give a protective effect against protein degradation caused by hyperglycemia, which may be helpful in the treatment of problems associated with diabetes.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135425469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination Of Vitamin C Stability In Different Packaging Materials At Refrigerated Conditions By Hplc Analysis","authors":"Pallavi R, Sushmitha KC, Anilakumar KR, Vanitha Reddy P","doi":"10.55691/2278-344x.1041","DOIUrl":"https://doi.org/10.55691/2278-344x.1041","url":null,"abstract":"The stability of Vitamin C depends on storage temperature, time, and packaging material. Vitamin C is known to prevent the oxidation of low-density lipoprotein primarily by scavenging the free radicals and other reactive oxygen species in the aqueous milieu, ascorbic acid combats cancer by promoting collagen synthesis and thus prevents tumors from invading other tissues. Aim: The present study aims at investigating the Vitamin C content of two citrus fruits under refrigerated conditions after a specific time interval, in different packaging materials. Material: In the present study, two citrus fruits – Amla & Lemon were used to study the stability of Vitamin C in different packaging materials viz., perforated zip lock cover, brown paper cover & plastic container under refrigerated conditions (5-6°C) at 0th day, 15th day, 30th day and 45th day. Vitamin C was estimated by the HPLC method and compared with the standard Ascorbic Acid. Results: The stability of Vitamin C in both Amla and Lemon stored in a perforated Zip lock cover was better than the other 2 packaging materials viz., Brown paper cover and Plastic container during the period of 0th to 45th day. The vitamin C content of Amla at 0th day - 200mg and 45th - day 163mg, and Lemon at 0th day - 43mg and 45th day - 26mg packed in perforated zip lock cover. Conclusion: From the present study it can be concluded that a perforated Zip lock cover is the most suitable packaging material for the retention of vitamin C under refrigerated condition","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135425462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aspect of sleep quality amid undergraduate medical students in correlation with BMI.","authors":"Pooja Pallavi, Suma Nataraj, Arun Gopi, Shobha Chikkavaddaragudi Ramachandra, Prashant Vishwanath, Akila Prashant","doi":"10.55691/2278-344x.1054","DOIUrl":"https://doi.org/10.55691/2278-344x.1054","url":null,"abstract":"Purpose: This study aimed to assess the quality of sleep among medical undergraduates from different phases of the medical program using the Pittsburgh Sleep Quality Index (PSQI) and to study the association of body mass index (BMI) with the quality of sleep among them. Material and Methods: Sleep quality was assessed among 482 medical undergraduates using the PSQI. Students undergoing treatment for psychiatric illness, diabetes or hypertension, history of alcohol consumption, and smoking were excluded from the study. Obesity was ascertained by calculating the BMI and categorized into 2 groups of23.0 according to the World Health Organization (WHO) guidelines for the Asian population. The chi-square test was utilized to compare seven components of PSQI and sleep quality for different phases and BMI groups and SPSS 24 was used to compare the components and the global score. Results: Only 0.8% of the total sample classified their sleep as very bad whereas 69.5% classified themselves as fairly good sleepers. The study participants had an average sleep time of 7.06±1.26 hours. The sleep duration (p23 had daytime dysfunction every day. Conclusions: It is necessary to create awareness among medical undergraduates about the importance of good sleep hygiene which will help them to improve their academic performance.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135424908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photocatalytic degradation of phenolic pollutants by Nanocomposites: A systematic review and pooled analysis","authors":"Rajesh Chethan, Shetty Utapal, Rajashekara Rakshitha, Nagaraju Chaithra, Nagaraju Pallavi","doi":"10.55691/2278-344x.1049","DOIUrl":"https://doi.org/10.55691/2278-344x.1049","url":null,"abstract":"All living things depend on water, which is a precious natural resource. Modern hydropower generation, industrial processes, and transportation increasingly rely significantly on water. Emerging contaminants are currently posing a serious threat to our environment and significantly damaging human health. To address these water-related problems, photocatalysis, one of the advanced oxidation processes, has drawn a lot of attention. The most common photocatalytic approach for the elimination of phenolic pollutants, which is one of the emerging pollutants in the aquatic environment, was determined through a systematic review of the scientific literature in the current study. Furthermore, It was thought about how independent variables like pollutant concentration, catalyst amount, radiation time, pH, and contact time might affect the process. Twelve research, all of which focused on phenolic contaminants, were included. In two studies, all 12 phenolic contaminants were eliminated. Most of the pollutants exhibited a degradation efficiency above 90%. The removal of organic contaminants from water can be accomplished with efficiency and effectiveness by using sophisticated photocatalytic treatment methods. However, the combined data support photocatalytic treatment procedures as a new technique in recent years for the removal of organic contaminants.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135425293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical and Bioactive Properties of Phlogacanthus and Andrographis Genus Plants: Potential for Post-Pandemic Home Remedies","authors":"Patipon Teerakitchotikan, Tibet Tangpao, Supattanakij Posawang, Smitha S. Bhat, Shashanka K. Prasadand, Sarana Rose Sommano","doi":"10.55691/2278-344x.1043","DOIUrl":"https://doi.org/10.55691/2278-344x.1043","url":null,"abstract":"This study aimed to differentiate the morphological characteristics, chemical constituents, and bioactive potential of Acanthaceae family plants, specifically three Phlogacanthus species and Andrographis paniculata. Under identical conditions, cutting stock plant of three Phlogacanthus species (Dee pla kung, Hom chang, and Cha hom) and Andrographis paniculata (Fah talai jone) were pruned and cultivated at the Chiang Mai Royal Agricultural Research Center. The morphology, biomass yield, and growth rates of the plants were observed after 90 days. Methanolic extracts of the dried aerial parts of these plants were analyzed for bioactive compounds, such as total phenolic content (TPC), total flavonoid content (TFC), total lactone content (TLC), and antioxidant activities (DPPH, ABTS, and FRAP assays). The results revealed that Hom chang had the maximum relative growth rate (RGR) of 2.64 x 10-3 cm/cm/day among the plants, as determined by the morphology analysis. Cha hom and Dee pla kung, on the other hand, had substantially greater biomass yields than the other species. Regarding chemical properties, Dee pla kung exhibited high TPC (13.66 ± 0.10 mg GAE/g), TFC (17.25 ± 0.31 mg CE/g), and TLC (9.57 ± 0.59%). In addition, Dee pla kung, a species of Phlogacanthus, exhibited significant antioxidant activity and was comparable to Fah talai jone (genus Andrographis) in terms of biomass yield and chemical properties. These findings lay the groundwork for creating future herbal remedies from local plants and their potential use in the medicinal industry.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135425292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Change Management in Education","authors":"Betsurmath CG, Prashanth Sadashiva Murthy","doi":"10.55691/2278-344x.1040","DOIUrl":"https://doi.org/10.55691/2278-344x.1040","url":null,"abstract":"Social challenges are constantly evolving and organizations need to adapt timely improvisations to stabilize the growth amidst these presenting challenges. The word “social challenges” itself is so varied in its representation, that it circumscribes various “planned” and “forced” challenges and threats that innately has the potential to destabilize the more so stable flow of processes. Educational institutions are expected to steer a variety of domains for a cumulative stable and progressive outcome. When the stakes at hand are so diverse and the challenges so intense, there is no landmark recipe that can be a single solution to all challenging situations for any educational institution. Hence, it is imperative to have a collective observational array of various institution’s responsiveness and the resultant outcomes handy to plan the best permutation of the change management for the challenge at hand. This article focusses on the review of literature to collate the various change management outcomes undertaken by educational organizations to meet the potentially disruptive challenges.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135188072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ameliorating Effect Of Quercetin On Ethanol-Induced Liver Injury Via Targeting RISC Machinery","authors":"Lakshana D. Puttahanumantharayappa, Nirmala G. Sannappagowda, Varsha D. Shiragannanavar, Shreyas H. Karunakara, Prasanna K. Santhekadur","doi":"10.55691/2278-344x.1039","DOIUrl":"https://doi.org/10.55691/2278-344x.1039","url":null,"abstract":"Background : Over the past few decades, increased alcohol consumption has had deleterious effects on human health. Alcoholic fatty liver disease (AFLD) is becoming a major global challenge, as the currently approved drugs for AFLDs are subject to several side effects. This has broadened the scope of the use of natural compounds as therapeutics. Recent advances in nutraceuticals as therapeutics have shed light on fl avonoids such as Quercetin. It is a natural antioxidant of multiple dietary origins and has been extensively studied for its bene fi cial role as an anti-in fl ammatory and anti-cancer agent. Objective : Based on this framework, in the proposed study, we investigated the therapeutic role of Quercetin in Ethanol-induced liver damage using the Swiss Albino mice model and the hepatic cell line HepG2. Methodology : WST-1 assay was performed to access the effect of Quercetin on cell proliferation. The impact of Ethanol on the body and liver weights of mice was measured, and liver injury was determined by H & E staining and TMS. The mRNA expression levels of in fl ammatory genes (TNF-a , IL-6, and IL-1 b ) and SND1, a signi fi cant unit of the RNA-induced silencing complex (RISC), were analyzed. The liver enzyme levels were also measured. Results : Our experimental results showed that HepG2 cells treated with ethanol had a lower proliferation rate, which was later mitigated by treatment with quercetin. In the mice model, a considerable reduction in body weight was detected after ethanol treatment. Conversely, there was a signi fi cant elevation in liver weight and enzyme activity. All of these effects were ameliorated by Quercetin treatment. Immunohistochemistry data revealed an improvement in the in fl ammation and fi brosis characteristics in liver tissues of the Quercetin-treated group. Decreased expression of in-fl ammatory markers and SND1 levels were also observed in the Quercetin-treated group. Conclusion : Based on our results it may be concluded that Quercetin demonstrated hepatoprotective activity in both ethanol-treated HepG2 cell line and ethanol-induced liver injury in mice model. Here, we elucidated a novel and possible therapeutic role of Quercetin in Alcohol-Related Liver Disease (ARLD) by targeting the RISC machinery.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75264145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aggression and MAO-A gene","authors":"Sacheta Sudhendra Kulkarni, S. S, K. Rao, Abhijith Devaraju","doi":"10.55691/2278-344x.1038","DOIUrl":"https://doi.org/10.55691/2278-344x.1038","url":null,"abstract":"","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"224 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86686249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Event of Intraoral Kinking of Endotracheal Tube Upon Prone Positioning in a Patient Undergoing Posterior Fossa Surgery","authors":"Sonali Turki, A. Barik, Amit Kumar Sharma, A. Arya","doi":"10.55691/2278-344x.1034","DOIUrl":"https://doi.org/10.55691/2278-344x.1034","url":null,"abstract":"A 10-year-old patient (Weight-28kg, Height-150cm), diagnosed case of cystic posterior fossa space occupying lesion with hydrocephalus was posted for craniotomy and excision under general anaesthesia in prone position. The patient was previously operated uneventfully under general anaesthesia for left medium pressure ventriculoperitoneal shunt in supine position. After standard general anaesthesia induction, the patient was intubated with 6.5 mm-cuffed/poly-vinyl-chloride (PVC) endotracheal tube (ETT). Unavail-ability of a wire-reinforced ETT of the desired size forced us to use the PVC tube. Endotracheal position was con fi rmed by bilateral chest auscultation and capnography. The tube was fi xed at 18 cm at oral margin after con fi rming the endotracheal location with fl exion and extension movement of neck. The patient was ventilated on a volume-controlled mode and end-tidal carbon dioxide was maintained between 30 and 35 mm Hg. Baseline peak airway pressure was noted to be 17cmH 2 O. Case speci fi c necessary vascular access were obtained. The patient was positioned prone after taking due precautions and a peak airway pressure of 18cmH 2 O was noted. Upon positioning of patient ' s head in Sugita head frame, peak airway pressures started to rise despite of maintaining two fi nger gap between chin and sternum, reaching a pressure limited peak pressure","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82657454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Adequacy of Training and Identification of Barriers to Choosing Academic Faculty Positions Among Psychiatry Postgraduate Students in India","authors":"R. Innamuri, Ambuja Dacha, Rajendhar Soorinedu, Siva Kumar Chennam Setty, K. Manohar Rao","doi":"10.55691/2278-344x.1032","DOIUrl":"https://doi.org/10.55691/2278-344x.1032","url":null,"abstract":"The increasing burden of psychiatric morbidity will proportionately increase the need for teachers of psychiatry in medical colleges. There are no studies on the current postgraduates ’ perception about taking up faculty positions. We conducted an online cross-sectional study among 101 postgraduate students using self-reporting questionnaires from October 2021 to November 2021. Majority were female, in 25-30 years age group, studying fi nal year in private medical colleges. They were willing consider teaching positions and expressed interest in training programs. There was perceived inadequacy of training in psychotherapy with majority of students seeking resources outside the teaching curriculum to make up for the de fi cits. Politics was reported as a signi fi cant barrier to taking up faculty positions in medical colleges.","PeriodicalId":54094,"journal":{"name":"International Journal of Health and Allied Sciences","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83564222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}