Revista Romana de Boli Infectioase最新文献

{"title":"Pneumonia stafilococică, o provocare actuală în practica pediatrică – prezentare de caz","authors":"Nicoleta-Ana Tomșa, Lorena Elena Meliț, Gabriela Bucur, Iunius Simu, Bianca Aron, C. Mărginean","doi":"10.37897/RJID.2020.4.10","DOIUrl":"https://doi.org/10.37897/RJID.2020.4.10","url":null,"abstract":"nicoleta-ana tomșa1, lorena elena meliț1,2, Gabriela Bucur1, iunius simu2,3, Bianca aron1, cristina oana mărginean1,2 1 Clinica Pediatrie, Spitalul Clinic Judeţean de Urgenţă, Tg. Mureş, România 2 Universitatea de Medicină şi Farmacie, Ştiinţe şi Tehnologie ,,G.E. Palade“, Tg. Mureş, România 3 Clinica Radiologie şi Imagistică Medicală, Spitalul Clinic Judeţean de Urgenţă, Tg. Mureş, România PREZENTĂRI DE CAZ","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45415004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of ulcerative colitis and Clostridium difficile infection at pediatric age – case presentation","authors":"A. Negrea, L. Meliț, A. Simon, Valentina Negrea, C. Mărginean, Tg. Mures Romania Tehnology","doi":"10.37897/RJID.2020.4.5","DOIUrl":"https://doi.org/10.37897/RJID.2020.4.5","url":null,"abstract":"Introduction. Ulcerative colitis (UC) is a more severe pathology in children than adults, with an increasing incidence in young ages. The most common exacerbations are due to Clostridium difficile (CD) infection and can lead to severe complications. case presentation. We present the case of a 6-year-old patient diagnosed with ulcerative colitis at the age of 5, admitted in our Clinic for watery diarrheic stools with blood, abdominal pain, anorexia, and weight loss. Laboratory tests at the time of admission revealed anemia, leukocytosis with neutrophilia, hydro-electrolytic disorders, and severe hypoalbuminemia. The A and B toxin detection test for CD in feces was positive, stool culture was negative. Anamnestic, clinical and paraclinical data established the diagnosis of CD infection associated with exacerbation of UC. Initially, the evolution under pulse therapy with Solu-Medrol and Metronidazole by vein was slightly favorable, but with a period of decline 5 days after the per oral administration of corticosteroids. Therefore, it was necessary to reinitiate intravenous corticosteroids associating also Vancomycin orally. Under the established treatment the symptomatology improved, with the normalization of the laboratory parameters and after 21 days of admission the patient was discharged. conclusions. The coexistence of CD infection in pediatric patients with UC remains a real challenge, due to the high rate of recurrence and higher mortality compared to the general population. The undulating evolution under treatment, as well as the psychological profile of the patient, have customized the case.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42549581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New perspectives on COVID-19 and pregnancy","authors":"Ana Duminică, V. Alexandrescu, A. Ciobanu, C. Gică, R. Botezatu, N. Gică, G. Peltecu, A. Panaitescu, B. Pharmacy","doi":"10.37897/RJID.2020.4.1","DOIUrl":"https://doi.org/10.37897/RJID.2020.4.1","url":null,"abstract":"Although there have been various pandemics throughout the history of humankind, modern age was thought to be ready to face such a challenge by implementing an advanced health care system. However, epidemic outbreaks are ubiquitous, and they have a substantial potential to evolve into pandemics, hence this being the actual context of SARS-CoV-2 pandemics from 2019. The difficulty of the addressed subject consists in the fact that the majority of pharmacological clinical studies omited pregnant patients. Acknowledging the physiological changes, pregnant women represent an unique group of patients as pregnancy could embody a particular substrate for this contemporary type of infection. © 2020, Amaltea Medical Publishing House. All rights reserved.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44282258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The susceptibility of pregnant women during viral pandemics – A mini-review","authors":"Astrit M. Gashi, Jakup Ismajli, Arjanit Sherifi, Gent Sopa, dardan ismajli","doi":"10.37897/RJID.2020.4.2","DOIUrl":"https://doi.org/10.37897/RJID.2020.4.2","url":null,"abstract":"The immune system is a system that consists of the reaction of the organism to the aggression of invading pathogens. The immune system is composed of: the innate immune system or nonspecific immunity, and the acquired immune system or specific immunity. During pregnancy, the maternal immune system changes constantly. The objective of this review is to evaluate the results from studies made in the field of reproductive immunology about the susceptibility of pregnant women to infectious diseases. Most studies show that pregnant women may be at a higher risk and more susceptible to infectious diseases. This is due to the continuous immune system modulating that occurs during pregnancy. This immunity modulated during normal pregnancy consists of decreased the acquired immune system or specific immunity (B-cells are absent, while T lymphocytes constitute about 3-10% of the decidual immune cells). We conclude that pregnant women may be at a higher risk and more susceptible to infectious diseases, including COVID-19. Therefore, we recommend special care and correct observance of measures such as social distancing, frequent hand washing, the use of masks, and all other measures that are given to the general population during viral pandemics, while pregnant women who become ill with COVID-19 should be treated aggressively. Furthermore, concrete plans must be developed (with more specific measures) for this higher-risk population, while ensuring that women receive the necessary care. © 2020, Amaltea Medical Publishing House. All rights reserved.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42341403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatita A, o patologie amenințătoare de viață la copiii mici cu boală Wilson – prezentare de caz","authors":"Cristian Dan Mărginean, Nicoleta-Ana Tomșa, Bianca Aron, Daniela Ciobanu, Lorena Elena Meliț, Spitalul Clinic Județean de Urgență Tg. Mureş România Clinica Pediatrie","doi":"10.37897/rjid.2020.3.12","DOIUrl":"https://doi.org/10.37897/rjid.2020.3.12","url":null,"abstract":"hepatomegalie, ecostructură hepatică inomogenă, ecogenitate granulară, cu micronoduli, diametrul venei porte 9 mm, pulsatilitate alterată venei porte, splenomegalie și ascită. En- doscopia digestivă superioară a arătat hiperemie și edem la nivelul mucoasei gastrice, cu cheaguri aderente la suprafața mucoasei și varice incipiente la nivelul fornixului gastric. Ecocardiografia a evidențiat colecție pleurală și pericardică în cantitate mică. exclus hepatita și C, toxoplasma, rubeola, herpes virus, Epstein Barr, citomegalovirusul hepatita autoimună. nivelurilor și cuprului seric, asociate cu testul pozitiv la D-penicilamină, împreună cu varicele gastrice și hipertensiunea portală, am stabilit diagnosticul de BW. Consultul oftalmologic și cel neurologic fost în relații normale. Evoluția clinică paraclinică pacientei fost favorabile după inițierea terapiei chelatoare. hepatita poate duce insuficiență hepatică special copiii antecedente patologice.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45897039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Main epidemiological features of COVID-19 cases admitted in a first line defence hospital from Bucharest, Romania","authors":"N. Nedelcu, “Dr. Victor Babes” Infectious, R. Mateescu, E. Ceaușu, P. Calistru, S. Florescu, B. Pharmacy","doi":"10.37897/rjid.2020.3.7","DOIUrl":"https://doi.org/10.37897/rjid.2020.3.7","url":null,"abstract":"In this retrospective unicenter study we aimed to outline the key features of the first 100 cases of COVID-19 hospitalized in our clinic after designation of it as front line unit for hospitalization of these cases. Thus, the average age of cases was 44.7 years (SD: 15.9) and the prevalence of female was 57.4%. By age groups, prevalence of young patients (7.8%) was significantly (p < 0.05) lower than the prevalence of adult patients (77.2%). The most prevalent occupation (31.7%) was healthcare worker. The most frecvent exposure to source of infection was represented by attending healthcare facilities (44.6%), followed by having contact with COVID-19 confirmed/suspect case (30.7%), and recent international travel (18.8%). Of the 30% of cases in which at least one health precondition was recorded the most prevalent (13.9%) of such condition was chronic cardiovascular disease including high blood presure. In regard with severity, to note that 6 patients died within 14 days of hospital admission, all fatalities have occurred in very old patients and 83.3% of them had chronic kidney disease. In the end, we express the hope that data outlined in this paper will help for better management of COVID-19 pandemic. © 2020, Amaltea Medical Publishing House. All rights reserved.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48874550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous involvement in COVID-19 patients","authors":"C. Beiu, B. Pharmacy, E. Ceaușu, M. Popa, M. Mihai, L. Popa, M. Popescu, C. Giurcaneanu","doi":"10.37897/rjid.2020.3.1","DOIUrl":"https://doi.org/10.37897/rjid.2020.3.1","url":null,"abstract":"The ongoing coronavirus disease 2019 (COVID-19) outbreak was declared a pandemic by the World Health organization in early March 2020. The disease typically presents with viral respiratory symptoms that could progress to acute respiratory dis-tress syndrome. Emerging evidence suggests different possible dermatologic manifestations of COVID-19, including: acral lesions (pernio-like, pseudo-chillblain), vesicular eruptions, macular and papular exanthema, urticaria, livedoid, purpuric and petechial rashes. However, specific skin manifestations of the COVID-19 disease have not yet been clearly established and the relationship between the appearance of skin lesions and SARS-CoV-2 infection is still unclear. These highly variable skin changes could represent a direct con-sequence of the viral infection, an immunological response to viral nucleotides, adverse reactions to drugs frequently used for the treatment of COVID-19, or other disorders. In a global effort to comprehend the exact cutaneous features of COVID-19, several international dermatological societies have initiated nationwide studies to analyze COVID-19 cutaneous manifestations during this pandemic. This paper represents a literature review of the scientific data available on the clinical characteristics and symptoms of the cutaneous manifestations associated with COVID-19. Such findings are extremely useful in establishing if dermatological manifestations in COVID-19 patients could harbor a diagnostic significance and subsequently be used as prognostic factors for outcomes of COVID-19. © 2020, Amaltea Medical Publishing House. All rights reserved.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48310884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiological aspects in patients diagnosed with SARS-CoV-2 infection – a literature review","authors":"M. Hoara, “Dr. Victor Babes” Infectious, A. Stoenescu, Nedeea Duță, P. Calistru, E. Ceaușu, S. Florescu, B. Pharmacy","doi":"10.37897/rjid.2020.2.3","DOIUrl":"https://doi.org/10.37897/rjid.2020.2.3","url":null,"abstract":"Currently, SARS-CoV-2 infection has affected the entire population of the globe, registering an alarming increase in the number of cases, but also in deaths. The main clinical expression of COVID-19 is pneumonia, for its evaluation being necessary an imaging characterization of lung lesions both by chest radiography and by computed tomography (CT) of the chest. Vari-ous studies performed on groups of patients revealed that CT examination is more accurately in diagnosing lung lesions at the onset of symptoms, but also before it. The most common lesions were multiple, bilateral, peripheral, in the lower lung fields. The appearance often varies between alveolar consolidation and ground-glass. Also, the data from the relevant studies emphasize the possibility of the existence of early pathological aspects on CT acquisitions, which do not involve clinical expression. Thus, it can be stated that both investi-gations are crucial in assessing the impact of the new coronavirus infection on the lung parenchyma, but also in guiding therapeutic management. © 2020, Amaltea Medical Publishing House. All rights reserved.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46507403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Particular evolutive modalities in SARS-CoV-2 infection","authors":"Ş. Lazăr, Adela Neculai, L. Musetescu, C. Marcu, S. Dinu, M. Nica, E. Ceaușu, S. Florescu, Carol Davila, B. Pharmacy","doi":"10.37897/rjid.2020.2.17","DOIUrl":"https://doi.org/10.37897/rjid.2020.2.17","url":null,"abstract":"The COVID-19 pandemic has challenged the medical world in many ways regarding diagnosis troubles and therapeutic options. In this paper, we will present three cases of patients from different age groups, in which we identified specific ways of evolution, from both clinically and laboratory data point of view. We used a critical evolution risk estimation calculator at admission and compared the results with the subsequent evolution of patients. From the analysis of the presented cases, we found persistent organic damage that will require their long-term follow-up. © 2020, Amaltea Medical Publishing House. All rights reserved.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41763864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute ischemic stroke in a patient with gastrointestinal complaints of COVID-19 infection","authors":"Oana Obrișcă, A. Arbune, M. Draghici, E. Davidescu, Ayghiul Mujdaba-Elmi, A. Dulamea, B. Pharmacy","doi":"10.37897/rjid.2020.2.19","DOIUrl":"https://doi.org/10.37897/rjid.2020.2.19","url":null,"abstract":"The most important pandemic in the last century triggered by SARS-CoV-2 infection is ongoing, and long-term implications are still unknown. We report the case of a 65-year old man, who presented with sudden onset of right-sided limb weakness, facial asymmetry, and dysarthria, accompanied by vomiting and headache. The initial neurological exam suggested acute stroke, although the cerebral CT-scan was not relevant neither recent ischemic, nor haemorrhage findings. According to the therapeutic protocol, intravenous thrombolytic therapy was timely administered, with a neurofluctuating course. The infusion was premature interrupted due to the sudden hematemesis, following by concurrent diarrhoea, abdominal cramps and recurrent vomiting. The new cerebral imaging confirmed the acute ischemic stroke in the vertebrobasilar territory and the abdominal CT-exam displayed an inflammatory aspect inflammation surrounding the right kidney and the proxi-mal colon, minimal right pleural effusion and hypo-ventilated areas in the pulmonary bases. The laboratory work-up revealed mild leukocytosis with neutrophilia, increased levels of D-dimers, altered renal function. Considering the epidemic COVID-19, a RT-PCR test for SARS-CoV-2 have been request and, surprisingly, it was positive. Previous unknown paroxysmal atrial fibrillation was found at admission by electrocardiography, suggesting the cardioembolic nature of the ischemic stroke, while a favouring role of infection is possible. The subsequent evolution was positive, following by the secondary prevention with oral anticoagulation, along with hypotensive and statin medication. Apart from the respiratory affection, COVID-19 infection can be present in patients with other major medical emergencies, including acute stroke, with no apparent sign of infection. Additional signs of gastrointestinal affection, along with attentive evaluation of abdominal CT-scan represent important hints for concomitant SARS-CoV-2 infection. © 2020, Amaltea Medical Publishing House. All rights reserved.","PeriodicalId":53394,"journal":{"name":"Revista Romana de Boli Infectioase","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44119719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}