Berkala Kedokteran最新文献

{"title":"EOSINOPHILS PROFILE AND LUND-MACKAY SCORE OF NASAL POLYPS IN ARIFIN ACHMAD HOSPITAL, RIAU PROVINCE","authors":"Yolazenia Yolazenia, Inayah Inayah, Febri Romaito Romaito, Retni Tri Handayani, Novisa Dwi Utami","doi":"10.20527/jbk.v18i1.12820","DOIUrl":"https://doi.org/10.20527/jbk.v18i1.12820","url":null,"abstract":"Abstract: Theories suggest that nasal polyps occur as a result of chronic inflammation of the nasal and sinus mucosa. Eosinophils are the main inflammatory cells found in nasal polyp tissue. The severity of nasal polyps can be seen from the CT Scan of the Paranasal Sinus (PNS) using the Lund-Mackay score. The purpose of this study was to determine the description of the eosinophil count of nasal polyp tissue and the Lund-Mackay score of CT Scan PNS of nasal polyps patients in Arifin Achmad Hospital, Riau Province. Examination of the eosinophil count was carried out microscopically using histopathological preparations of nasal polyp tissue with semiquantitative assessment, and Lund-Mackay score was assessed from the CT Scan of the PNS. From the 14 samples collected, there were 8 men (57.1%) more than 6 women (42.9%) with an average age of 30.43 ± 17.36 years old. Eosinophil counts were obtained in 5  (35,7%) samples 1/2+,  5 (35.7%) samples 1+, and negative in 4 samples (28,6%). While the Lund-Mackay score obtained an average value of 10.21 ± 6.87 with a low category in 11 (78.6%) and high in 3 (21.4%) samples. Patients with high Lund-Mackay scores tend to have higher eosinophil counts which reflect a more severe degree of disease severity in nasal polyps.Keywords: Eosinophil; Lund-Mackay Score; Nasal polyp; Paranasal sinus","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47976104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AMPUTATION OF CERVIX AND NEOCERVIX CREATION USING STURMDORF TECHNIQUE IN RECURRENT CERVICAL SARCOMA BOTRYOIDES: A CASE REPORT","authors":"Pribakti Budinurdjaja, Ihya Ridlo Nizomy, Inas Tsurayya Fauziah Lahdimawan","doi":"10.20527/jbk.v18i1.12851","DOIUrl":"https://doi.org/10.20527/jbk.v18i1.12851","url":null,"abstract":"Abstract: Sarcoma botryoides, or embryonal rhabdomyosarcoma, is soft tissue sarcoma arises from embryonic muscle cells and normally present with discharge, bleeding, or a visible mass at the vaginal introitus in infants and children. Aim of this study is to report a case of cervical sarcoma botryoides. Method used is a Case report. A 16-year-old girl, nulliparous, complained abnormal vaginal bleeding and a protruding vaginal mass. Patient underwent first surgery, mass recurrent five months later. The second surgery was performed by cervical amputation and neocervix creation using Sturmdorf sutures technique. Postoperative week 12 demonstrated a healthy neocervix in appearance, her menses have resumed, indicated patency. She has no evidence of disease 3 months after diagnosis. Cervical sarcoma botryoides is a rare malignancy. Clinicians must thoroughly examine any polyp or mass protrudes from vagina. Early diagnosis and treatment are essential for better prognosis. Sarcoma botryoides has a much improved prognosis with multimodality treatment. To determine the long-term survival and future potential fertility outcome, larger study and longer follow-up are needed. Keywords: sarcoma, botyroides, embryonal, rhabdomyosarcoma, neocervix","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44131409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MENTAL EMOTIONAL DISORDERS IN INTERSTITIAL CYSTITIS PATIENTS","authors":"Fajar Gemilang Ramadani, N. R. Perdana, Anidiah Novy Hasdi, Dina Aulia Fakhrina","doi":"10.20527/jbk.v18i1.12802","DOIUrl":"https://doi.org/10.20527/jbk.v18i1.12802","url":null,"abstract":"Abstract: Interstitial cystitis is a chronic pain condition with unclear underlying etiology. Interstitial cystitis has a relation with psychological disorders. There has been an increase in visit patients diagnosed with interstitial cystitis at the urology clinic at Dr. H. Moch. Ansari Saleh Hospital since October 2020. The objectives of this study are to compare mental emotional disorder events in interstitial cystitis patients and control subjects and to determine the relationship between interstitial cystitis and the incidence of mental emotional disorders. included 62 subjects, classified into 2 groups, namely: patients diagnosed with interstitial cystitis based on medical records data at the Urology Clinic, Dr. H. Moch. Ansari Saleh Hospital, and control subjects who had never been diagnosed with interstitial cystitis and had no symptoms and complaints of interstitial cystitis. Both groups completed the Self Reporting Questionnaire SRQ-20 to assess the presence of mental emotional disorders. The incidence of mental emotional disorders in interstitial cystitis patients and controls were compared, and the odds ratios (OR) for the presence of a mental emotional disorder were determined. A total of 32 patients with interstitial cystitis and 30 controls were included in this study. There were 14 interstitial cystitis patients and 4 control subjects who had mental emotional disorders, respectively, and the difference was significant (p = 0.008). Patients with interstitial cystitis were 5 times more at risk of experiencing mental emotional disorders than the control group (OR = 5,056). Patients with interstitial cystitis have a significantly higher risk of experiencing mental emotional disorders compared to those without interstitial cystitis. Screening might be beneficial to assess their mental emotional health. It may be necessary to collaborate with a psychiatrist to treat these patients holistically.Keywords: Interstitial cystitis; Mental emosional disorder","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48054013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NEURO PROGENITOR CELLS (NPCS) AND PPARγ EXPRESSION IN THE BRAIN OF PROTEIN-DEFICIENT RATS AFTER ADMINISTRATION OF PASAK BUMI (Eurycoma longifolia Jack) EXTRACT","authors":"D. Sanyoto, T. Triawanti, Dimas Ikhsan Airlangga","doi":"10.20527/jbk.v18i1.12798","DOIUrl":"https://doi.org/10.20527/jbk.v18i1.12798","url":null,"abstract":"Abstract: Malnutrition due to protein deficiency disrupts the neurogenesis process that affects cell development and brain function. One of the efforts to overcome the matter is to use the pasak Bumi (Eurycoma longifolia Jack) which has compounds believed to increase the process of neurogenesis. The aim of study to analyze the effect of pasak bumi extract on the expression of NPCs (Tuj-1) and PPARγ cell in the brains of malnourished rats. Groups of experimental animals that were were divided into 5 groups, namely (P1) malnourished rats + placebo (aquades); (P2) malnourished rats + pasak bumi extract (EPB) 7,5 mg/kg BW; (P3) malnourished rats + EPB 15 mg/kg BW; (P4) malnourished rats + EPB 22,5 mg/kg BW; (P5) malnourished rats + EPB 30 mg/kg BW. As a control, normal rats were used which were given a placebo. Parameters examined include Tuj-1 and PPARγ using immunohistochemistry procedure. The results showed that the P3 group (15 mg/kg BW) had more cells expressing Tuj-1 than the other doses. There was a significant difference between the KP and the P3, P4, and P5 groups. There was no significant difference in the expression of PPARγ in all malnourished groups with EPB and KN intervention. Conclusion: extract of pasak bumi was able to improve the neurogenesis process in malnutrition but not PPARγ. Keywords: Malnutrition, pasak bumi extract, NPCs, Tuj-1, PPARγ","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47510408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE RELATIONSHIP BETWEEN KNOWLEDGE AND ATTITUDE WITH EFFORT OF SCHISTOSOMIASIS PREVENTION BY COMMUNITY IN THE WORK AREA PUBLIC HEALTH CARE CENTER OF WUASA","authors":"Noviany Banne Rasiman","doi":"10.20527/jbk.v18i1.12819","DOIUrl":"https://doi.org/10.20527/jbk.v18i1.12819","url":null,"abstract":"Abstract: Schistosomiasis is a disease caused by worm Schistosoma japonicum which requires an intermediate animal, namely a snail called Oncomelania Hupensis Lindoensis. In the work area Health Care Canter of Wuasa, the disease is still many cases, because most of the population are immigrants, they are open rice fields and plantations in the focus area of snail. The purpose was to determine the relationship between knowledge and attitudes with the effort of Schistosomiasis prevention by Community in the Public Health Care Center of Wuasa, North Lore District, Poso Regency. This type of research is analytic with cross sectional approach. The variables in this study are the knowledge and attitudes of the community with efforts to prevent Schistosomiasis. The types of data are primary and secondary. data collection using a questionnaire. Data analysis used univariate and bivariate analysis with Chi-square test. The population in this study were all people of North Lore District. Sampling using proportional random sampling technique with total 99 respondents. The results of the univariate analysis showed that 77.8% of respondents had good knowledge of schistosomiasis prevention efforts, 52.5% of respondents had good attitudes and 83.8% of respondents had quite good schistosomiasis prevention efforts. Bivariate analysis with Chi-square statistical test with 95% confidence level with a significance value of 0.05. The results showed that there was a relationship between knowledge and efforts to prevent Schistosomiasis with p-value = 0.000 (where p < 0.05) and there was a relationship between community attitudes and efforts to prevent Schistosomiasis disease with p-value = 0.003 (where p < 0.05). The conclusion of the study were there is a significant relationship between knowledge and attitudes of the community with efforts to prevent Schistosomiasis in the Public Health Care Center of Wuasa. Suggestions to the health workers in the work area of health care center to increase local community awareness in supporting the prevention of Schistosomiasis disease.Keywords: Knowledge; attitude; prevention; Schistosomiasis.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45183330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Colonies Number of the Germs Formed Post Operation between the Utilization of Single, Double, and Orthopedic Gloves in Closed Fracture Operations More Than 2 Hours","authors":"Deni Maulana, Y. Ismiarto, W. Arsa","doi":"10.20527/jbk.v17i2.11676","DOIUrl":"https://doi.org/10.20527/jbk.v17i2.11676","url":null,"abstract":"Abstract: Post-operative infection is still one of the most common nosocomial diseases that can cause great losses because it will increase the length of stay, use of drugs, and reduce the quality of life of the patients. The risk will increase if the number of colonies is> 105 bacteria per gram of tissue. Various ways have been done to reduce the number of bacteria in the operation area, including the use of surgical gloves. This study analyzed the comparison of the level of bacterial colonies that grew on the surface of single, double, and orthopedic surgical gloves in closed fracture management for more than 2 hours at Hasan Sadikin Hospital. The statistical analysis was done with p-value = 0.011 (<0.05), which means a significant difference in the number of germ colonies that grow between single, double, and orthopedic gloves. Double gloves and orthopedic gloves have a better ability to reduce bacterial colony growth. Meanwhile, there was no significant difference in the number of bacterial colonies formed between double gloves and orthopedics. Perforation is a factor affecting the number of germ colonies that formed. The use of double gloves and orthopedic gloves in closed fracture surgery for more than 2 hours shows the number of bacterial colonies formed is less than single gloves. There was a significant difference in the rate of perforation between standard surgical gloves and orthopedic gloves. Keywords: Bacteria colony, Single glove, Double glove, Orthopaedic glove, Perforation","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45551682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concomittan Hyperuricemia and Abcess Mid Thoracic Region: The Use of Dual Energy CT Scan","authors":"F. Makkiyah","doi":"10.20527/jbk.v17i2.11678","DOIUrl":"https://doi.org/10.20527/jbk.v17i2.11678","url":null,"abstract":"Abstract: Dual energy scan was performed to differentiate any collection associated with calsium. Case report. This 23 year old man showed severe hyperuricemia and mid thoracic pain and MRI showed collection over posterior epidural thecal sac over T3 until T9. Dual energy CT scan was performed to assess uric acid crystal over thoracic region. The CT result was negative. He was treated over intravenous antibiotic and pain medication. His pain improved  progressively and laboratory results  showed towards normal  value and he was discharged on day twelveth. Conclusion. This case report showed the comprehensive diagnostic tool to yield out the aetiology of  thoracal epidural collection, despite negative result. Keywords: Hyperuricemia, abcess, mid thoracic, dual energy, CT scan","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42517642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between Hemoglobin Reticulocytes and Ferritin in Chronic Kidney Disease Patients Undergoing Hemodialysis at PKU Bantul","authors":"Muhammad Salman Shalahuddin, L. Rosita","doi":"10.20527/JBK.V17I2.11674","DOIUrl":"https://doi.org/10.20527/JBK.V17I2.11674","url":null,"abstract":"Abstract: As many as 7 – 12% of the world's population has chronic kidney disease (CKD). CKD patients can experience various complications, one of which is anemia. Anemia can cause a variety of cardiovascular complications in CKD patients. Enforcement of the diagnosis of anemia and its type is carried out by laboratory examination, among others by examination of reticulocytes-hemoglobin (ret-he) and iron status such as serum ferritin. Examination of these parameters can help in planning the right treatment for CKD patients who have anemia. The purpose of this study was to determine the relationship of Ret-he with ferritin levels in CKD patients undergoing hemodialysis at PKU Bantul Hospital. This study used cross-sectional method. The data source used was secondary data obtained from medical records and the Indonesian Renal Registry (IRR). Sampling research used consecutive sampling method. The analysis used univariate analysis which was frequency distribution table, and bivariate analysis. Univariate analysis obtained that average levels of ret-he from 50 subjects was 28.87 ± 3.75 pg and median serum ferritin levels were 118,1 (9,76 – 1615) mL. Bivariate analysis with pearson correlation test found a significant correlation between serum ret-he and ferritin levels (r = 0.498, p = 0.000).There was a significant correlation between he-ret levels and serum ferritin levels Keywords: chronic kidney disease, anemia, reticulocytes-hemoglobin, serum ferritin.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41866452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amyand’s Hernia: A Rare Case Report","authors":"Fadli Robby Amsriza, Rizka Fakhriani","doi":"10.20527/JBK.V17I2.11677","DOIUrl":"https://doi.org/10.20527/JBK.V17I2.11677","url":null,"abstract":"Abstract: Amyand’s hernia is described in the inguinal hernia sac as being the presence of an appendix vermiformis. It is a rare condition the incidence is about 1 per cent of all inguinal hernias. It is often diagnosed incidentally during inguinal hernia surgery. The main treatment method of Amyand’s hernia is surgery. We report a case of 63 years old man who presented with right inguinal groin bulge for 1 month with the previous repaired right inguinal hernia 5 years ago. On clinical examination revealed a 6 cmx8 cm firm, nontender, irreponible mass in the right inguinal region. He was diagnosed as right sided irreponible inguinal hernia. He was undergoing the elective surgery. Intra-operative, the hernia sac was laterally found in the inferior epigastric vessels and separated from sperm cord to deep inguinal ring. The hernia sac was opened. A non-inflamed appendix was seen. Appendectomy was performed, and the hernia was repaired by Halsted’s repair. Amyand’s hernia is a rare condition. The correct diagnosis is usually made intraoperative.   Keywords: Amyand’s hernia, appendectomy, hernia repair, inguinal hernia.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47661745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Knowledge of Lombok Praya-Indonesia Regional Community on the Safety Use of Medicinal Plants","authors":"Wiwied Ekasari, Suko Hardjono, S. Sugijanto, J. Ekowati, I. N. Wijaya, T. Widiandani","doi":"10.20527/jbk.v17i2.11671","DOIUrl":"https://doi.org/10.20527/jbk.v17i2.11671","url":null,"abstract":"Abstract: The use of medicinal plants to maintain or overcome health problems has long been carried out by worldwide community. Along with the development of knowledge, data about the existence of undesirable effects or side effects associated with the use of medicinal plants that are not appropriate are obtained. This research is conducted to determine public knowledge about the safety several medicinal plants use. The study was conducted with a questionnaire technique in Lombok Praya, Indonesia. The results show that knowledge about the safety of the use of medicinal plants in breastfeeding mothers obtains the correct answer by 48%, knowledge about the parts of medicinal plants that are dangerous for consumption by 39% and knowledge about medicinal plants that can increase health risks by 21%. Whereas, the knowledges for the use of medicinal plants in pregnant women and the use of medicinal plants that are not right obtains very good results with correct answers of 79% and 81%. Based on further interviews, these good results are obtained because they are supported more by traditional use of the plant that has already existed in the area. Public understanding of the safety of some medicinal plants in Lombok Praya is still lacking. It is necessary to add knowledge about the use of medicinal plants that requires special attention, especially on plants that are often used by people in the area. Local health agencies need to disseminate information on the safety of medicinal plants that is wider and more sustainable. Keywords: Community, medicinal plant, safety, public understanding.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49653829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}