北京大学班图分校血液透析慢性肾脏病患者血红蛋白网织细胞与铁蛋白的相关性

Muhammad Salman Shalahuddin, L. Rosita
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摘要

摘要:世界上有多达7 - 12%的人口患有慢性肾病(CKD)。慢性肾病患者会出现各种并发症,其中之一就是贫血。贫血可引起CKD患者多种心血管并发症。对贫血及其类型的诊断是通过实验室检查进行的,其中包括网状红细胞血红蛋白(ret-he)和铁状态(如血清铁蛋白)的检查。检查这些参数可以帮助计划正确的治疗CKD患者贫血。本研究的目的是确定在PKU Bantul医院接受血液透析的CKD患者Ret-he与铁蛋白水平的关系。本研究采用横断面法。使用的数据来源是从医疗记录和印度尼西亚肾脏登记处(IRR)获得的二手数据。抽样研究采用连续抽样方法。分析采用单因素分析(即频率分布表)和双因素分析。单因素分析50例受试者血清ret-he平均水平为28.87±3.75 pg,血清铁蛋白水平中位数为118.1 (9,76 ~ 1615)mL。双因素分析pearson相关检验发现血清ret-he与铁蛋白水平具有显著相关性(r = 0.498, p = 0.000)。关键词:慢性肾病,贫血,网织红细胞血红蛋白,血清铁蛋白
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation between Hemoglobin Reticulocytes and Ferritin in Chronic Kidney Disease Patients Undergoing Hemodialysis at PKU Bantul
Abstract: As many as 7 – 12% of the world's population has chronic kidney disease (CKD). CKD patients can experience various complications, one of which is anemia. Anemia can cause a variety of cardiovascular complications in CKD patients. Enforcement of the diagnosis of anemia and its type is carried out by laboratory examination, among others by examination of reticulocytes-hemoglobin (ret-he) and iron status such as serum ferritin. Examination of these parameters can help in planning the right treatment for CKD patients who have anemia. The purpose of this study was to determine the relationship of Ret-he with ferritin levels in CKD patients undergoing hemodialysis at PKU Bantul Hospital. This study used cross-sectional method. The data source used was secondary data obtained from medical records and the Indonesian Renal Registry (IRR). Sampling research used consecutive sampling method. The analysis used univariate analysis which was frequency distribution table, and bivariate analysis. Univariate analysis obtained that average levels of ret-he from 50 subjects was 28.87 ± 3.75 pg and median serum ferritin levels were 118,1 (9,76 – 1615) mL. Bivariate analysis with pearson correlation test found a significant correlation between serum ret-he and ferritin levels (r = 0.498, p = 0.000).There was a significant correlation between he-ret levels and serum ferritin levels Keywords: chronic kidney disease, anemia, reticulocytes-hemoglobin, serum ferritin.
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