Minerva Urology and Nephrology最新文献

{"title":"Beyond the price tag: reassessing the value of robotic surgery in urologic oncology.","authors":"Filippo Turri, Bernardo Rocco, Federico Piramide, Paolo Dell'oglio, Angelo Mottaran, Carlo A Bravi, Marco Paciotti, Gabriele Source, Edward Lambert, Christoph Wurnschimmel, Mike Wenzel, Nikolaos Liakos, Ruben DE Groote, Iulia Andras, Marco Sandri, Chiara Sighinolfi","doi":"10.23736/S2724-6051.25.06548-6","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06548-6","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 3","pages":"435-437"},"PeriodicalIF":4.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From planning to prognosis: predicting renal function after minimally-invasive partial nephrectomy with artificial intelligence.","authors":"Daniele Amparore, Alberto Piana, Andrea Simeri, Vincenzo Pezzi, Michele DI Dio, Cristian Fiori, Gianluigi Greco, Francesco Porpiglia","doi":"10.23736/S2724-6051.25.06520-6","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06520-6","url":null,"abstract":"<p><p>This study presents a machine learning model to predict renal function decline following minimally-invasive partial nephrectomy. Using a dataset of 556 patients treated between 2015 and 2023, the model incorporated patient, tumor, and intraoperative surgical variables - including clamping strategy, resection technique, and renorrhaphy type - to estimate the 3-month postoperative eGFR drop. A Random Forest Regressor outperformed other models, achieving a prediction accuracy of 89.29%, a mean absolute error of 8.09 mL/min/1.73 m², and a strong correlation with observed outcomes (r=0.904, P<10^-42). These findings support the use of AI for personalized surgical planning and functional outcome prediction in nephron-sparing surgery.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 3","pages":"401-407"},"PeriodicalIF":4.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Avoiding pelvic lymph node dissection in intermediate-risk prostate cancer with negative PSMA PET: a step toward personalized surgery.","authors":"Angelo Orsini, Rossella Cicchetti, Alessio Digiacomo, Riccardo De Archangelis, Martina Basconi, Giulio Litterio, Luigi Schips, Michele Marchioni","doi":"10.23736/S2724-6051.25.06510-3","DOIUrl":"10.23736/S2724-6051.25.06510-3","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 3","pages":"422-424"},"PeriodicalIF":4.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can all surgical trainees be trained to proficiency for a robotic urethro-vesical anastomotic task using a chicken model? A prospective, randomized trial.","authors":"Stefano Puliatti, Marco Amato, Marco Ticonosco, Rui Farinha, Ruben De Groote, Laura Langhendries, Maxime Lassel, Ahmed Eissa, Ben VAN Cleynenbreugel, Elio Mazzone, Stefania Ferretti, Salvatore Micali, Giampaolo Bianchi, Alexandre Mottrie, Anthony G Gallagher","doi":"10.23736/S2724-6051.25.06367-0","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06367-0","url":null,"abstract":"<p><strong>Background: </strong>Proficiency based progression (PBP) is a very effective method of training and has been adopted by the European Robotic Surgical Section (ERUS) for robotic skills training. No study has addressed whether all learners can be trained to the proficiency benchmark. In this study, we evaluated: 1) if all trainees reached a quantitatively defined proficiency benchmark for a robotic suturing and knot tying anastomosis task; and 2) the number of training trials required.</p><p><strong>Methods: </strong>In a multi-center, prospective, randomized, study, 48 participants were randomized to: 1) a PBP group that received e-learning on the ORSI chicken anastomosis task with the requirement to reach the proficiency benchmark before starting practical training; 2) e-learning group, received the exact same curriculum as group 1, but with no proficiency requirement on the e-learning; 3) traditional group received the exact same curriculum in face-to-face lectures; 4) the apprenticeship group received a conventional preparation.</p><p><strong>Results: </strong>All participants, except five in group 4, demonstrated the proficiency benchmark. Group 1 took ~6 trials (~3 hours); group 2 required 14% longer, group 3, 103% (P<0.001) and in group 4, 58% of trainees demonstrated the benchmark but took 162% (P<0.001) longer. This was a small-scale but robust study with substantial effect sizes.</p><p><strong>Conclusions: </strong>All PBP trainees demonstrated the proficiency benchmark in comparison to 58% of conventional trained group. As adherence to the PBP methodology decreased, the efficiency of proficiency demonstration significantly reduced.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From laparoscopic to robot-assisted extravesical ureteral reimplantation: evolution of a new standard treatment for pediatric vesicoureteral reflux.","authors":"Ciro Esposito, Lorenzo Masieri, Mariapina Cerulo, Fulvia Del Conte, Francesco Tedesco, Vincenzo Coppola, Annalisa Chiodi, Claudia DI Mento, Marco Chiarenza, Giorgia Esposito, Leonardo Continisio, Marco Castagnetti, Maria Escolino","doi":"10.23736/S2724-6051.25.06127-0","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06127-0","url":null,"abstract":"<p><strong>Background: </strong>This paper aimed to compare laparoscopic (LEVUR) vs. robot-assisted (REVUR) Lich Gregoir extravesical ureteral reimplantation (UR) in children with vesicoureteral reflux (VUR).</p><p><strong>Methods: </strong>The charts of all patients with moderate to high-grade VUR (3 to 5), who received LEVUR or REVUR over a 10-year period (2014-2024), were retrospectively reviewed.</p><p><strong>Results: </strong>Seventy-six patients (40 girls and 36 boys), with median age of 5.7 years (range 2-11) and moderate to high-grade VUR, were enrolled. VUR was unilateral in 55/76 (72.3%) and bilateral in 21/76 (27.7%). Patients were grouped according to the MIS approach and pathology side. The median operative time (OT) of unilateral non-dismembered UR was similar in LEVUR (65 min) and REVUR (50 min) (P=0.56). REVUR was faster than LEVUR in unilateral dismembered (90 vs. 120 min) (P=0.001) and bilateral UR (105 vs. 160 min) (P=0.001). The radiographic VUR resolution rate was similar between REVUR and LEVUR (97.8% vs. 96.7%) (P=0.89). Two patients (2.6%) reported low-grade persistent reflux without need for additional treatments. Mild bladder dysfunction developed in 2/21 (9.5%) undergoing bilateral UR (Clavien-Dindo 2).</p><p><strong>Conclusions: </strong>REVUR is technically easier, faster and provides better ergonomics compared to LEVUR. The postoperative outcomes are excellent in both techniques, with success rates higher than 95%. Complications developed after bilateral reimplantation in patients who had previous history of bladder dysfunction. Given the robot availability, we believe that the best indication for LEVUR remains unilateral reflux without need for ureteral tapering. In unilateral refluxing megaureter, para-ureteral diverticulum or bilateral cases, REVUR represents the best choice.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organ-sparing robotic-assisted radical cystectomy in men: description of technique and outcomes.","authors":"Lazaros Tzelves, Elizabeth Day, Amit Bhudia, Mark Markov, Osama Al-Bermani, Joanna Olphert, Zafer Tandogdu, Ashwin Sridhar, John Kelly, Anthony Ta","doi":"10.23736/S2724-6051.25.06170-1","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06170-1","url":null,"abstract":"<p><strong>Background: </strong>Organ sparing radical cystoprostatectomy in males is being considered with skepticism due to fear of compromising oncological safety; however, sacrifice of erectile nerves can lead to quality of life deterioration due to erectile dysfunction.</p><p><strong>Methods: </strong>Data from men with muscle-invasive bladder cancer (MIBC) who were potent and wish to preserve potency were collected prospectively. Both nerve-sparing and capsule-sparing approach (with or without seminal vesicle preservation) was performed in a high-volume center. Baseline characteristics, oncological and sexual outcomes were collected. International Index for Erectile Function-5 (IIEF-5) was used both preoperatively and at last follow-up. Potency was defined as a score ≥3 in question 2.</p><p><strong>Results: </strong>Twenty-five patients were included in capsule-sparing and 15 in nerve-sparing group. Patients in the former group were younger (55 vs. 66 years old) but no other significant difference in baseline characteristics was noted. Perioperative outcomes were similar among groups, whilst no difference was found regarding overall survival, recurrence rate, incidental prostate cancer and positive surgical margins. Postoperative IIEF-5 score was higher in capsule-sparing group (14 vs. 7, P=0.016) and more patients were potent (18 vs. 3, P=0.004). In regression analysis, the only significant predictor of potency was capsule-sparing surgery (odds ratio: 8.58, 95% CI: 1.30-81.5, P=0.034).</p><p><strong>Conclusions: </strong>Capsule-sparing and nerve-sparing approaches during robotic radical cystectomy are feasible techniques among carefully selected patients, with improved sexual and non-inferior oncological outcomes compared with standard approach.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparison on the efficiency and safety between two morcellators for laser enucleation of the prostate: Piranha versus Cyber Blade. A randomized controlled trial.","authors":"Davide Perri, Federica Mazzoleni, Jean-Baptiste Roche, Javier Romero-Otero, Andrea Pacchetti, Flavio C Mattuzzi, Thomas Knoll, Evangelos Liatsikos, Panagiotis Kallidonis, Antonio L Pastore, Alexander Govorov, Giorgio Bozzini","doi":"10.23736/S2724-6051.25.06051-3","DOIUrl":"10.23736/S2724-6051.25.06051-3","url":null,"abstract":"<p><strong>Background: </strong>We performed a comparison between the Wolf^® Piranha^™ and the Quanta System^® Cyber Blade^™ morcellators for the Thulium laser enucleation of the prostate (ThuLEP).</p><p><strong>Methods: </strong>Overall, 205 patients underwent ThuLEP in three urologic departments (Como, Bordeaux, Madrid). Patients were randomized to Piranha morcellator with disposable blades (100 cases, Group A) or Cyber Blade morcellator (105 cases, Group B). Morcellation efficiency was related to prostate volume (PV) using the cut-off of 100 mL. Complication rate and device malfunctions were reported. The Chi-square Test was used for the comparison of the study groups. All statistical tests were two-sided with a level of significance at P<0.05.</p><p><strong>Results: </strong>Mean PV was 82.5 vs. 91.9 mL (P=0.21) in Group A vs. B. Mean morcellation time was 9.7 vs. 10.1 min in Group A vs. B when PV was ≤100 mL (P=0.34), it was significantly lower in Group B when PV was >100 mL (12.7 vs. 10.1 min, P=0.04). Similarly, morcellation efficiency was comparable when PV was ≤100 mL (8.5 vs. 9.1 g/min, P=0.08), while it was significantly higher with the Cyber Blade when PV was >100 mL (10.0 vs. 12.3 g/min, P=0.04). Bladder injury occurred in three and two cases in Group A and B. Complication rate was comparable.</p><p><strong>Conclusions: </strong>Piranha and Cyber Blade morcellators showed a comparable efficacy when PV was ≤100 mL, while efficacy was significantly higher with the Cyber Blade when PV was >100 mL. Both instruments are safe and reliable according to the risk of bladder injury and the occurrence of mechanical problems.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"256-261"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radical cystectomy for bladder cancer in solid organ transplant recipients.","authors":"Elena Tonin, Lorenzo Bianchi, Angelo Mottaran, Stephan Brönimann, Florian Berndl, Stefano Biolcati, Matteo Droghetti, Francesco Chessa, Benjamin Pradere, Eva Comperat, Riccardo Schiavina, Eugenio Brunocilla, Shahrokh F Shariat, David D'Andrea","doi":"10.23736/S2724-6051.25.06130-0","DOIUrl":"10.23736/S2724-6051.25.06130-0","url":null,"abstract":"<p><strong>Background: </strong>Solid organ transplant recipients (SOTRs) face higher cancer risk because of immunosuppressive therapy used to prevent organ rejection. We hypothesized that SOTRs treated with radical cystectomy (RC) and pelvic lymph-node dissection (PLND) for bladder cancer (UBC) might have worse survival outcomes compared to non-SOTRs. This study aims to assess survival outcomes of SOTRs treated with RC and PLND for UBC compared to non-SOTRs.</p><p><strong>Methods: </strong>A retrospective analysis of 645 patients treated with RC and PLND for UBC, originating from our multicenter cooperation program (2002-2022), stratified in two groups according to previous solid organ transplantation. Co-primary endpoints were OS and CSS, assessed using mixed-effects Cox-analysis. Secondary endpoints included postoperative complications, readmission-rates, operation time, estimated blood loss and length of stay.</p><p><strong>Results: </strong>Of the 361 patients analyzed (median follow-up: 17 months), 23 were SOTRs. SOTRs exhibited lower 12-month (70% vs. 80%) and 24-month (36% vs. 68%) OS-rates compared to non-SOTRs (P=0.011). Corresponding CSS-rates were also lower for SOTRs at 12 (81% vs. 85%) and 24 months (55% vs. 76%) (P=0.016). Multivariable Cox-regression identified a prior solid organ transplant (OR:5.2; P=0.002), higher pathologic-stage (OR:3.8; P=0.03 for pT2, OR:3.6; P=0.04 for pT3, OR:4.5; P=0.03 for pT4), and administration of \"any systemic treatment\" (OR:0.3; P=0.001) as OS predictors. For CSS, predictors were a prior solid organ transplant (OR:3.0; P=0.03), higher pathologic-stage (OR:9.8; P=0.04 for pT3, OR:13; P=0.02 for pT4), and administration of \"any systemic treatment\" (OR:0.4; P=0.03).</p><p><strong>Conclusions: </strong>Solid organ transplant recipients undergoing RC and PLND for urinary UBC have worse survival outcomes compared to non-SOTRs. Our findings may impact patient counseling, follow-up, and planning future clinical trials.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"202-208"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular events after kidney cancer surgery: insights from a comprehensive national database.","authors":"Francesco Lasorsa, Angelo Orsini, Gabriele Bignante, Arianna Biasatti, Luca Lambertini, Michele Marchioni, Matteo Pacini, Kyle A Dymanus, Francesco Del Giudice, Rocco Damiano, Savio D Pandolfo, Cristian Fiori, Srinivas Vourganti, Edward E Cherullo, Pasquale Ditonno, Giuseppe Lucarelli, Riccardo Autorino","doi":"10.23736/S2724-6051.25.06097-5","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06097-5","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study is to compare the occurrence of major cardiovascular events (MCEs) after partial nephrectomy (PN) and radical nephrectomy (RN), and to identify risk factors for their development, including the impact of social determinants of health (SDOH).</p><p><strong>Methods: </strong>We used the PearlDiver™ Mariner database (Pearl-Diver Technologies, Colorado Springs, CO, USA) for this analysis. At 1- and 5-year after surgery, the following MCEs were described by using proper ICD-9/10 diagnostic codes: myocardial infarction, cerebrovascular diseases, congestive heart failure, and peripheral vascular diseases. Risk factors for overall risk of MCEs within 5 years after surgery were assessed using multivariable logistic regression analysis.</p><p><strong>Results: </strong>A total of 44,455 and 46,295 patients underwent PN and RN, respectively. Statistically significant differences were reported with RN group being characterized by higher rates per each of these events. At a multivariable analysis, RN was associated with a significantly greater likelihood of MCEs (OR 1.51, 95% CI 1.46-1.56, P=0.001), so as age at surgery, male gender, preoperative diabetes mellitus, hypertension and dyslipidemia, tobacco use, history of myocardial infarction and congestive heart failure, presence of SDOH and end-stage renal disease. Our study acknowledges limitations including potential misclassification and lack of detailed clinical data in the PearlDiver Mariner database.</p><p><strong>Conclusions: </strong>Kidney cancer surgery is associated with a non-negligible risk of MCEs. Even after taking into consideration comorbidities and history of cardiovascular diseases, RN continues to independently increase the risk of MCEs. Moreover, social disparities, as measured by the SDOH, play a crucial role in risk of MCEs in patients undergoing surgery for kidney cancer.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"233-238"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total hospital cost of robot-assisted approach in major urological cancer surgeries.","authors":"Francesco DI Bello, Natali Rodriguez Peñaranda, Andrea Marmiroli, Mattia Longoni, Fabian Falkenbach, Quynh C LE, Zhe Tian, Jordan A Goyal, Claudia Collà Ruvolo, Gianluigi Califano, Massimiliano Creta, Fred Saad, Shahrokh F Shariat, Salvatore Micali, Gennaro Musi, Alberto Briganti, Markus Graefen, Felix H Chun, Nicola Longo, Pierre I Karakiewicz","doi":"10.23736/S2724-6051.25.06282-2","DOIUrl":"10.23736/S2724-6051.25.06282-2","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to test for differences in total hospital cost (THC) between robot-assisted vs. open partial nephrectomy (PN), radical cystectomy (RC), radical prostatectomy (RP) and radical nephroureterectomy (NU).</p><p><strong>Methods: </strong>Within the National Inpatient Sample (2010-2019), we identified all robot-assisted vs. open PN, RC, RP and NU patients. Multivariable Poisson regression models were fitted.</p><p><strong>Results: </strong>Of all surgeries, 22,572 (56%) were robot-assisted PN (RPN), 5114 (24%) were robot-assisted RC (RARC), 99,134 (70%) were robot-assisted RP (RARP), and 1138 (24%) patients were robot-assisted NU (RNU). Relative to open surgery, RARC (115,511 vs. 103,531$), RNU (64,761 vs. 54,768$), RARP (49,629 vs. 40,850$) and RPN (56,288 vs. 50,875$) were associated with higher THC (all P<0.001). After multivariable adjustment, RARP (risk ratio [RR]: 1.25), RNU (RR: 1.13), RPN (RR: 1.11) as well as RARC (RR: 1.10) independently predicted higher THC (all P<0.001). Additionally, Charlson Comorbidity Index ≥2 (RR: from 1.07 to 1.08), large bed size hospitals (RR: from 1.03 to 1.08), length of stay (RR: from 1.02 to 1.06), and overall complications (RR: from 1.09 to 1.19) invariably predicted higher THC.</p><p><strong>Conclusions: </strong>THC is invariably higher when robot-assisted approach is applied instead of open approach in PN, RC, RP and NU patients. This THC disadvantage of robot-assisted approach requires consideration in the light of other benefits of robot-assisted surgery that could not be addressed in the current analyses.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"217-225"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}