Minerva Urology and Nephrology最新文献

{"title":"Waterjet ablation therapy vs. urethral-sparing robot-assisted simple prostatectomy for large prostate volumes (>80 mL): results of a retrospective multicentric series according to the standardized BPH6 achievement.","authors":"Umberto Anceschi, Francesco Tedesco, Daniele Amparore, Eugenio Bologna, Giampaolo Siena, Loris Cacciatore, Salvatore Basile, Andrea Cocci, Francesco Prata, Rocco S Flammia, Sabrina De Cillis, Francesco Sessa, Alfredo M Bove, Lorenzo Viola, Andrea Iannuzzi, Alberto Ragusa, Aldo Brassetti, Riccardo Mastroianni, Gabriella Mirabile, Flavia Proietti, Leslie C Licari, Ashanti Zampa, Alberto Quarà, Michele Ortenzi, Enrico Checcucci, Cristian Fiori, Francesco Porpiglia, Andrea Minervini, Vito Pansadoro, Costantino Leonardo, Giuseppe Simone","doi":"10.23736/S2724-6051.25.06084-7","DOIUrl":"10.23736/S2724-6051.25.06084-7","url":null,"abstract":"<p><strong>Background: </strong>The introduction of minimally invasive techniques for BPH treatment aimed to balance de-obstruction with maintenance of ejaculatory function. The aim of this multicentric series was to compare outcomes of waterjet ablation therapy (WAT) versus urethral-sparing robot assisted simple prostatectomy (us-RASP) for large prostate volumes (PV>80 mL) according to BPH-6 metric.</p><p><strong>Methods: </strong>Four institutional BPH datasets were matched and queried for \"PV>80 mL\" (N.=86), \"WAT\" (Group A; N.=42) and \"us-RASP\" (Group B; N.=44). Baseline, perioperative and functional data according to BPH6 composite endpoint were compared between groups. Differences between continuous variables were assessed with t-test or Mann-Whitney U-test depending on their normal or not normal distribution, while Chi-square Test was used for categorical data. A two-sided P<0.05 was considered significant.</p><p><strong>Results: </strong>Patients treated with WAT showed lower preoperative PSA median values (3.5 vs. 7.07 ng/mL) (P<0.05). Regarding perioperative outcomes, patients treated with us-RASP revealed increased median operative time (110 vs. 70 mins), prolonged bladder irrigation time (24 vs. 37.2 hours), longer median hospital stay (5 vs. 4 days), respectively (all P<0.05). At a median follow-up of 43.7 months (IQR 33.8-49.7), the BPH6 achievement rate was comparable between groups (54.7% vs. 56.8%; P=0.964). In the WAT series 1-year ejaculatory dysfunction rate was 19.1% while in the us-RASP cohort was 13.6%, respectively (P=0.21). Retrospective design and the lack of a propensity-score matching represent main limitations of this study.</p><p><strong>Conclusions: </strong>Compared to us-RASP, WAT showed comparable symptom relief and ejaculatory function preservation for prostate gland >80 mL with benefit in terms of main perioperative outcomes at mid-term follow-up.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"247-255"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From nocturnal awakenings to nocturnal voiding: the relationship between insomnia and nocturia - a systematic review.","authors":"Irina Verbakel, George Boukheir, Donald Bliwise, Dirk Vogelaers, Francois Hervé, Jeffrey Weiss, An Mariman, Karel Everaert","doi":"10.23736/S2724-6051.23.05384-3","DOIUrl":"10.23736/S2724-6051.23.05384-3","url":null,"abstract":"<p><strong>Introduction: </strong>The aim of this study was to systematically evaluate relevant literature regarding 1) the prevalence of nocturia in patients with insomnia; 2) sleep characteristics of insomniacs with and without nocturia; 3) interventions for the treatment of insomnia and their effect on nocturia.</p><p><strong>Evidence acquisition: </strong>A systematic review of literature was performed through EMBASE, MEDLINE, CLINICALTRIALS.GOV and CENTRAL databases up until November 2022 according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement. From the identified reports, 11 studies were retained, of which 7 were eligible for meta-analysis. Bias assessment was performed using the ROBINS tools as per the Cochrane collaboration guidelines.</p><p><strong>Evidence synthesis: </strong>A total of 5396 older adults were included in the meta-analysis. The pooled estimate of the OR was 1.958 (95% CI: 1.609-2.384) for nocturia in patients with insomnia based on 7 studies in a random effects model with nonsignificant heterogeneity (I²=50.83%, P=0.06). Wake after sleep onset (WASO) was longer in people with insomnia and nocturia compared to those without and sleep efficiency (SE) declined. Interventions with melatonin, diet and behavioral therapy were beneficial on nocturia frequency in insomniacs. A limiting factor of our analysis was the scarcity of available data, potentially causing an important selection bias.</p><p><strong>Conclusions: </strong>The overall odds for nocturia in older adults is higher in patients with insomnia than those without and is associated with worse sleep outcomes. Interventions for treating insomnia such as melatonin, behavioral therapy and diet show beneficial results on nocturnal voiding frequency. We advocate for further research in which uniform definitions and questionnaires are used. Routine screening for nocturia in patients with insomnia could be beneficial to maximize sleep quality improvement.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"181-191"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between MET c.3328G>A p.Val1110Ile mutation and renal cell carcinomas in a specific population: data on histology, focality, onset and the need for surgery from a monocentric study.","authors":"Angelo Porreca, Stefania Zovato, Marco Rinaldi, Luca Di Gianfrancesco, Isabella Mammi, Filippo Marino, Gianluca Giannarini, Alessandro Crestani","doi":"10.23736/S2724-6051.24.05998-6","DOIUrl":"10.23736/S2724-6051.24.05998-6","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"274-275"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of efficacy and safety of fluoroscopy-free and conventional retrograde ureteroscopy for urolithiasis: a systematic review and metanalysis of randomized controlled trials.","authors":"Luiz G Serrão Gimenez, Diogo Souto Santana, Guilherme M Maia Lopes, Rafael Baldissera Cardoso, Breno Cordeiro Porto, Carlo Camargo Passerotti, Rodrigo A da Silva Sardenberg, Jose Pinhata Otoch, Jose A Shiomi DA Cruz","doi":"10.23736/S2724-6051.25.06087-2","DOIUrl":"10.23736/S2724-6051.25.06087-2","url":null,"abstract":"<p><strong>Introduction: </strong>Urolithiasis is a highly prevalent condition and its definitive treatment with endourological procedures exposes patients and medical staff to ionizing radiation. The efficacy and safety of fluoroscopy-free ureteroscopy (FF-URS) over conventional ureteroscopy (CV-URS) are controversial.</p><p><strong>Evidence acquisition: </strong>We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) data comparing FF-URS to CV-URS in patients undergoing treatment for ureteral or kidney stones.</p><p><strong>Evidence synthesis: </strong>Eight randomized controlled trials (RCTs) were included in the meta-analysis, comprising 873 patients. Of these, 440 (50.4%) patients underwent FF-URS. The meta-analysis revealed no statistically significant difference in stone-free rate (SFR) between the two groups (RR=0.99; 95% CI 0.94-1.04; P=0.65; I²=0%). Similarly, there was no difference in the overall complication rates (8.4% vs. 9.7%; RR 0.87; 95% CI 0.57-1.31; P=0.50; I²=0%), Clavien-Dindo I/II (RR=0.68; 95% CI 0.42, 1.10; P=0.12; I²=0%) and operative time (MD 1.58 min; 95% CI -0.02-3.18; P=0.05; I²=16%). Clavien-Dindo III occurred only in one patient (0.2%) in the FF-URS group.</p><p><strong>Conclusions: </strong>FF-URS is effective and safe compared to CV-URS and can reduce radiation exposure for both patients and medical staff without compromising treatment outcomes.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"162-170"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The future of BPH treatment: is a new paradigm at our doorstep?","authors":"Paolo Geretto, Sabrina De Cillis, Mikolaj Przydacz","doi":"10.23736/S2724-6051.24.06294-3","DOIUrl":"10.23736/S2724-6051.24.06294-3","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"271-273"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative complications during radical cystectomy: a detailed analysis of intraoperative vascular injuries.","authors":"Kaushik P Kolanukuduru, Neeraja Tillu, Arjun Venkatesh, Osama Zaytoun, Maurizio Buscarini","doi":"10.23736/S2724-6051.24.06030-0","DOIUrl":"10.23736/S2724-6051.24.06030-0","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"275-277"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cyber Ho generator with Magneto technology: the first experience of a new concept of hybrid HoLEP.","authors":"Davide Perri, Umberto Besana, Federica Mazzoleni, Matteo Maltagliati, Andrea Pacchetti, Tommaso Calcagnile, Giorgio Bozzini","doi":"10.23736/S2724-6051.25.06384-0","DOIUrl":"10.23736/S2724-6051.25.06384-0","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"277-279"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Partial penectomy with reconstruction using a split-thickness skin graft: a multicenter experience.","authors":"Mateusz Czajkowski, Bartosz Małkiewicz, Katarzyna Czajkowska, Piotr M Wierzbicki, Adrian Poterek, Roman Sosnowski, Małgorzata Sokołowska-Wojdyło, Tomasz Szydełko, Marzena Kogut-Wierzbicka, Marcin Matuszewski","doi":"10.23736/S2724-6051.24.05924-X","DOIUrl":"10.23736/S2724-6051.24.05924-X","url":null,"abstract":"<p><strong>Background: </strong>Penile cancer is a relatively rare neoplasm in developed countries, with the majority of newly diagnosed cases presenting as organ-confined, with a 5-year survival rate of 90%. Therefore, it is crucial to consider the impact of penile tumor resection on sexual and urinary function. Regrettably, the literature is devoid of comprehensive, step-by-step video instructions for the surgical procedure of partial penectomy with reconstruction using a split-thickness skin graft (0.3 mm). This study aimed to demonstrate a step-by-step video of the partial penectomy technique with reconstruction using a split-thickness skin graft and to present the outcomes of this procedure.</p><p><strong>Methods: </strong>This multicenter study was initiated in April 2019 and completed in February 2023, enrolling 54 male patients who underwent partial penectomy and reconstruction using a split-thickness skin graft (0.3 mm). The study collected data on the local recurrence rates, overall survival, sexual and voiding functions and complications.</p><p><strong>Results: </strong>The average patient age was 61.26 years old (range: 26-82 years). Following penile-sparing surgery, a substantial proportion of patients exhibited favorable results. Among the 54 patients, 37 (68.5%) were classified as sexually active and 50 (92.6%) demonstrated good voiding function. Excellent cosmetic outcomes were achieved in 52 patients (96.3%), and the average size of the negative resection margins was 4.75±4.162 mm (range: 0.5 to 20 mm). Notably, no positive margins were observed. Patient outcomes depend on the tumor stage and histologic grade rather than the size of the surgical margin.</p><p><strong>Conclusions: </strong>Partial penectomy with reconstruction using a split-thickness skin graft has excellent oncological, functional, and cosmetic outcomes.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"262-270"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of patient education on adherence to treatment regimen and quality of life in hemodialysis patients: a systematic review and meta-analysis.","authors":"Bushra Sultan, Erika S Froelicher","doi":"10.23736/S2724-6051.24.05718-5","DOIUrl":"https://doi.org/10.23736/S2724-6051.24.05718-5","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Hemodialysis constitutes a protracted therapeutic intervention for renal failure, characterized by symptoms that exert a considerable toll on quality of life owing to their intensity and frequent recurrence. Patient education and engagement has been shown to enhance adherence, thereby improving treatment effectiveness and quality of life. The objective of this systematic review was to assess the effectiveness of patient education on improving adherence to treatment and enhancing quality of life among individuals undergoing hemodialysis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Evidence acquisition: &lt;/strong&gt;The systematic review and meta-analysis followed PRISMA's Preferred Reporting Item for Systematic Review and Meta-Analysis guidelines. The studies were evaluated utilizing the Joanna Briggs Institute methodology. The search utilized several databases including PubMed, CINAHL, Ovid, Wiley Online Library, Springer Link, and Google Scholar. Studies that specifically examined treatment adherence encompassing aspect such as fluid restriction, dietary modification, medication usage, electrolyte balance, and interdialytic weight management) as well as those assessing quality of life were included in this review.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Evidence synthesis: &lt;/strong&gt;A total of 15 studies met the inclusion criteria. The studies explored adherence to various facets of treatment including fluids and electrolytes management (potassium, phosphate, creatinine level), medication usage (compliance with prescribe medication), dietary practices (adaptation according to disease and hemodialysis requirement), interdialytic weight management, and quality of life. Seven of these studies focus on investigating the quality of life, while the remaining eight examined specific components of treatment adherence. Due to the variation in methods, the results are described narratively. A quantitative synthesis was conducted using Revman 5.0 to assess the impact of educational intervention. This meta-analysis evaluated the pooled effects of adherence to fluids, electrolytes (creatinine), diet, and quality of life. A significant improvement is shown in fluid adherence (MD=35.18, 95% CI: 22.35, 48.0) (overall effect Z=5.38, P&lt;0.0001), dietary modification (MD=37.50, 95% CI: 24.65, 50.35) (Overall effect Z=5.72, P=0.0001), and quality of life (MD=8.50, 95% CI: 4.50, 12.50, (overall effect Z=4.17, P=0.0001). However, no significant effect is observed on the creatinine level (MD=-0.50, 95% CI: -1.38, 0.38) (Z=1.12, P=0.026). The observed level of heterogeneity ranged from low to moderate.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Hemodialysis impacts various aspects of patients' lives. This systematic review shows that nursing education and behavior monitoring in patients undergoing hemodialysis contributes to improving their adherence to treatment and quality of life. The evaluated pooled effect and mean difference in meta-analysis findings shows that the educational interventions improv","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective and multicenter validation of the BETTY score for predicting perioperative outcomes after elective urological surgery.","authors":"Alessandro Uleri, Michael Baboudjian, Gilles Pasticier, Victor Basset, Guillaume Cordier, Bernard Malavaud, Pourya Pashootan, Jean-Baptiste Beauval, Guillaume Ploussard","doi":"10.23736/S2724-6051.25.06041-0","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06041-0","url":null,"abstract":"<p><p>Postoperative complications remain a significant challenge in surgical care. This study assessed the ability of the BETTY score, a novel user-friendly scoring system, to predict postoperative outcomes in a large multicenter cohort of urological surgeries. We conducted a post-hoc analysis of a prospective, nonrandomized multicenter trial including 415 patients undergoing elective urological surgeries in six French hospitals. The BETTY score, part of a smartphone app, incorporates pre- and intraoperative data to classify patients into risk categories. We evaluated multiple endpoints, including 90-day postoperative overall and major complications, length of stay, prolonged care after discharge, unplanned readmission, reoperation, and days alive and out of hospital. Of the 415 patients, 22% experienced postoperative complications, with 3.9% major complications. Unplanned readmissions, prolonged care after discharge, and reoperation occurred in 8%, 20%, and 2.4% of cases, respectively. We found significant correlations between the BETTY score and all endpoints analyzed. In multivariate analysis, the BETTY score was significantly associated with all postoperative events studied. These findings demonstrate the reliability of the BETTY score in predicting various postoperative outcomes in urological surgery patients, especially for patients undergoing major surgeries. This tool may help optimize perioperative care and improve patient outcomes, potentially contributing to more personalized surgical care.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}