Francesco DI Bello, Natali Rodriguez Peñaranda, Andrea Marmiroli, Mattia Longoni, Fabian Falkenbach, Quynh C LE, Zhe Tian, Jordan A Goyal, Claudia Collà Ruvolo, Gianluigi Califano, Massimiliano Creta, Fred Saad, Shahrokh F Shariat, Salvatore Micali, Gennaro Musi, Alberto Briganti, Markus Graefen, Felix H Chun, Nicola Longo, Pierre I Karakiewicz
{"title":"Total hospital cost of robot-assisted approach in major urological cancer surgeries.","authors":"Francesco DI Bello, Natali Rodriguez Peñaranda, Andrea Marmiroli, Mattia Longoni, Fabian Falkenbach, Quynh C LE, Zhe Tian, Jordan A Goyal, Claudia Collà Ruvolo, Gianluigi Califano, Massimiliano Creta, Fred Saad, Shahrokh F Shariat, Salvatore Micali, Gennaro Musi, Alberto Briganti, Markus Graefen, Felix H Chun, Nicola Longo, Pierre I Karakiewicz","doi":"10.23736/S2724-6051.25.06282-2","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06282-2","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to test for differences in total hospital cost (THC) between robot-assisted vs. open partial nephrectomy (PN), radical cystectomy (RC), radical prostatectomy (RP) and radical nephroureterectomy (NU).</p><p><strong>Methods: </strong>Within the National Inpatient Sample (2010-2019), we identified all robot-assisted vs. open PN, RC, RP and NU patients. Multivariable Poisson regression models were fitted.</p><p><strong>Results: </strong>Of all surgeries, 22,572 (56%) were robot-assisted PN (RPN), 5114 (24%) were robot-assisted RC (RARC), 99,134 (70%) were robot-assisted RP (RARP), and 1138 (24%) patients were robot-assisted NU (RNU). Relative to open surgery, RARC (115,511 vs. 103,531$), RNU (64,761 vs. 54,768$), RARP (49,629 vs. 40,850$) and RPN (56,288 vs. 50,875$) were associated with higher THC (all P<0.001). After multivariable adjustment, RARP (risk ratio [RR]: 1.25), RNU (RR: 1.13), RPN (RR: 1.11) as well as RARC (RR: 1.10) independently predicted higher THC (all P<0.001). Additionally, Charlson Comorbidity Index ≥2 (RR: from 1.07 to 1.08), large bed size hospitals (RR: from 1.03 to 1.08), length of stay (RR: from 1.02 to 1.06), and overall complications (RR: from 1.09 to 1.19) invariably predicted higher THC.</p><p><strong>Conclusions: </strong>THC is invariably higher when robot-assisted approach is applied instead of open approach in PN, RC, RP and NU patients. This THC disadvantage of robot-assisted approach requires consideration in the light of other benefits of robot-assisted surgery that could not be addressed in the current analyses.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"217-225"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Letizia M Jannello, Mario De Angelis, Carolin Siech, Francesco Di Bello, Natali Rodriguez Peñaranda, Zhe Tian, Jordan A Goyal, Stefano Luzzago, Francesco A Mistretta, Marco Tozzi, Fred Saad, Felix K Chun, Alberto Briganti, Stefano Puliatti, Nicola Longo, Ottavio De Cobelli, Gennaro Musi, Pierre I Karakiewicz
{"title":"Validation of lymphovascular invasion as a predictor of lymph-node invasion in squamous cell carcinoma of the penis.","authors":"Letizia M Jannello, Mario De Angelis, Carolin Siech, Francesco Di Bello, Natali Rodriguez Peñaranda, Zhe Tian, Jordan A Goyal, Stefano Luzzago, Francesco A Mistretta, Marco Tozzi, Fred Saad, Felix K Chun, Alberto Briganti, Stefano Puliatti, Nicola Longo, Ottavio De Cobelli, Gennaro Musi, Pierre I Karakiewicz","doi":"10.23736/S2724-6051.24.05938-X","DOIUrl":"10.23736/S2724-6051.24.05938-X","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to validate lymphovascular invasion (LVI) as a predictor of lymph-node invasion (LNI) in squamous cell carcinoma of the penis (SCCP).</p><p><strong>Methods: </strong>Within the Surveillance, Epidemiology, and End Results database (2010-2020), we identified SCCP patients who underwent lymphadenectomy with known LVI status. Univariable logistic regression models (LRMs) addressed LNI. Harrell's concordance index (c-index) quantified accuracy after 2000 bootstrap resamples for internal validation. Multivariable LRMs included the most informative, statistically significant predictors. Subgroup analyses were repeated in organ-confined (T1b-T2) and non-organ confined (T3-T4) stages.</p><p><strong>Results: </strong>Of 586 SCCP patients, 219 (37%) had LVI. LVI was associated with higher rate of LNI (66 vs. 43%; P<0.001). Positive predictive value of LVI was 66 vs. 57% for negative predictive value. In multivariable LRMs, LVI independently predicted LNI (Odds ratio [OR]: 2.41; P<0.001). Bootstrap-adjusted c-index of multivariable model was 0.570 without LVI vs. 0.639 with LVI. In subgroup analyses, LVI independently predicted LNI in organ-confined (OR: 2.23; P<0.001) and in non-organ confined stages (OR: 3.10; P<0.001). In subgroup analyses, addition of LVI increased c-index from 0.530 to 0.595 in organ-confined and from 0.599 to 0.682 in non-organ confined.</p><p><strong>Conclusions: </strong>The current study validates LVI as an independent predictor of LNI in SCCP. LVI increases the accuracy of LNI predictions in the overall cohort as well as in organ-confined and non-organ confined stages. However, stage and grade even with the added consideration of LVI are not accurate enough to provide LNI prediction in individual patients.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"226-232"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Simona Presutti, Enrico Panio, Camilla Nero, Roberto Iacovelli, Luca Tagliaferri, Marco Campetella, Emilio Sacco, Giuseppe Pallotta, Bernardo Rocco, Maria C Sighinolfi
{"title":"BRCA2 and genetic mutations in prostate cancer: an updated practical guide on \"when and how\" testing across international guidelines.","authors":"Simona Presutti, Enrico Panio, Camilla Nero, Roberto Iacovelli, Luca Tagliaferri, Marco Campetella, Emilio Sacco, Giuseppe Pallotta, Bernardo Rocco, Maria C Sighinolfi","doi":"10.23736/S2724-6051.25.06395-5","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06395-5","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"152-155"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chiara Re, Mattia Longoni, Giuseppe Rosiello, Enrico Finazzi Agrò, Paolo Gontero, Francesco S Grossi, Vincenzo Mirone, Carmelo Morana, Richard Naspro, Francesco Montorsi
{"title":"Current management of patients affected by benign prostatic hyperplasia: a multi-institutional study from a contemporary large Italian cohort.","authors":"Chiara Re, Mattia Longoni, Giuseppe Rosiello, Enrico Finazzi Agrò, Paolo Gontero, Francesco S Grossi, Vincenzo Mirone, Carmelo Morana, Richard Naspro, Francesco Montorsi","doi":"10.23736/S2724-6051.24.05957-3","DOIUrl":"10.23736/S2724-6051.24.05957-3","url":null,"abstract":"<p><strong>Background: </strong>Despite a large amount of literature focused on pharmacologic and surgical therapy for benign prostate hyperplasia (BPH), little is known about clinical presentation and management of outpatient clinic patients. We aimed to conduct a tailored analysis of BPH-affected patients, comparing men with known BPH versus newly diagnosed. The analysis was made through International Prostate Symptom Score (IPSS) and BPH Impact index (BII).</p><p><strong>Methods: </strong>\"Intensive prostate benefit\" project working group designed a questionnaire prospectively administered by urologists to patients affected by lower urinary tract symptoms (LUTS) related to BPH.</p><p><strong>Results: </strong>Overall, 3198 (64%) patients were previously diagnosed with BPH versus 1800 (36%) received a first diagnosis. Patients previously diagnosed with BPH were older (median 69 vs. 66 years) and more comorbid (P<0.001). Moreover, median IPSS score was higher in these patients (16 vs. 14), who also experienced a higher rate of severe symptoms (32.0% vs 21.5%, P<0.0001). At BII, concerns for one's health and time lost due to urinary problems were higher in patients previously diagnosed with BPH (P<0.0001). In these patients, a BPH-specific therapy was already established (88.5% vs. 75.1%) and a higher rate of therapy adherence (55.0% vs. 27.0%, P<0.0001) was observed. Roughly 90% of patients already taking BPH therapy changed their therapy after urological examination. In these patients, supplements/phytotherapeutics, alpha blockers, 5-alfa-reductase inhibitors, were prescribed in 32.8%, 37.4%, 17.4%, respectively.</p><p><strong>Conclusions: </strong>Patients with prior BPH diagnosis have severe LUTS that worsen over time, affecting quality of life despite treatment. LUTS management in primary care is crucial, emphasizing counseling for a healthy lifestyle, cardiovascular risk control, and medication adherence.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"239-246"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rosario Leonardi, Guglielmo Mantica, Francesca Ambrosini, Alessandro Calarco, Antonio Tufano, Patricia Borges DE Souza, Massimiliano Mazza, Sara Bravaccini
{"title":"The current status of biomarkers for bladder cancer: progress and challenges.","authors":"Rosario Leonardi, Guglielmo Mantica, Francesca Ambrosini, Alessandro Calarco, Antonio Tufano, Patricia Borges DE Souza, Massimiliano Mazza, Sara Bravaccini","doi":"10.23736/S2724-6051.25.06372-4","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06372-4","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"149-151"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Savino Sciascia, Grazia D Bonelli, Marta Calatroni, Vincenzo L'imperio, Roberta Fenoglio, Lorenza M Argolini, Camillo Carrara, Nicola Lepori, Francesco Reggiani, Alessandra Bortoluzzi, Fausta Catapano, Mariele Gatto, Chiara Tani, Elisa Longhitano, Maurizio Garozzo, Barbara Trezzi, Emanuele Conte, Domenico Santoro, Maria Gerosa, Marta Mosca, Renato A Sinico, Gabriella Moroni, Dario Roccatello
{"title":"Different clusters in patients with lupus podocytopathy identified by clinical-pathological characteristics.","authors":"Savino Sciascia, Grazia D Bonelli, Marta Calatroni, Vincenzo L'imperio, Roberta Fenoglio, Lorenza M Argolini, Camillo Carrara, Nicola Lepori, Francesco Reggiani, Alessandra Bortoluzzi, Fausta Catapano, Mariele Gatto, Chiara Tani, Elisa Longhitano, Maurizio Garozzo, Barbara Trezzi, Emanuele Conte, Domenico Santoro, Maria Gerosa, Marta Mosca, Renato A Sinico, Gabriella Moroni, Dario Roccatello","doi":"10.23736/S2724-6051.25.06306-2","DOIUrl":"10.23736/S2724-6051.25.06306-2","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"159-161"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luca Lambertini, Matteo Pacini, Ruben S Calvo, Juan R Torres Anguiano, Donato Cannoletta, Greta Pettenuzzo, Fabrizio DI Maida, Francesca Valastro, Andrea Mari, Gabriele Bignante, Francesco Lasorsa, Hakan B Haberal, Alessandro Zucchi, Andrea Minervini, Simone Crivellaro
{"title":"Retroperitoneal single port vs. transperitoneal multiport robot assisted partial nephrectomy in patients with highly hostile abdomen: comparative analysis from a tertiary care center.","authors":"Luca Lambertini, Matteo Pacini, Ruben S Calvo, Juan R Torres Anguiano, Donato Cannoletta, Greta Pettenuzzo, Fabrizio DI Maida, Francesca Valastro, Andrea Mari, Gabriele Bignante, Francesco Lasorsa, Hakan B Haberal, Alessandro Zucchi, Andrea Minervini, Simone Crivellaro","doi":"10.23736/S2724-6051.25.06245-7","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06245-7","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to explore perioperative and functional outcomes in a cohort of patients with highly hostile abdomens treated with retroperitoneal (RP) single port vs transperitoneal multiport robot assisted partial nephrectomy.</p><p><strong>Methods: </strong>Clinical and surgical data of all consecutive patients treated with transperitoneal multiport and RP single-port robot assisted partial nephrectomy between March 2019 and January 2024 were prospectively collected and retrospectively analyzed. The presence of \"hostile abdomen\" was defined as personal history of at least one major abdominal surgery. Multivariable logistic regression analysis was used to assess independent predictors of Trifecta achievement.</p><p><strong>Results: </strong>Overall, clinical and surgical data of 247 consecutive patients were prospectively collected, of these 71 met the inclusions criteria and were retrospectively analyzed. No differences emerged in baseline features. Previous surgery proximity to the site of partial nephrectomy was found comparable among groups (P=0.21). RP single port group showed a significantly lower operative time (171 vs. 235 min, P=0.02) and estimated blood loss (70 vs. 100 cc, P=0.04) while open conversion was significantly higher (9.3%) in case of multiport treatment (P=0.001). A significative lower rate of major postoperative complications (7.1% vs. 16.3%, P=0.03) as well as 90-days readmissions (P=0.04) was found in case of single port RP procedures. Adjusting for age, BMI and CCI, RP single port approach was confirmed as independent predictor of Trifecta achievement (OR 1.62 CI 1.18-2.35 P=0.01).</p><p><strong>Conclusions: </strong>In patients treated with RAPN with highly hostile abdomens, the adoption of a single port RP approach reduces the major complication rate as compared to the multiport transperitoneal approach also improving EBL, operative time, LOS and pain management.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"209-216"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Lucia Gallo, Sabrina De Cillis, Riccardo Lombardo, Véronique Phé, Vincenzo Li Marzi, Cosimo De Nunzio, Alessandro Giammò
{"title":"The \"gender-gap\" problem of artificial urinary sphincter: the future is robotic.","authors":"Maria Lucia Gallo, Sabrina De Cillis, Riccardo Lombardo, Véronique Phé, Vincenzo Li Marzi, Cosimo De Nunzio, Alessandro Giammò","doi":"10.23736/S2724-6051.25.06298-6","DOIUrl":"10.23736/S2724-6051.25.06298-6","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"156-158"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudia Collà Ruvolo, Simone Morra, Francesco Di Bello, Simone Cilio, Agostino Fraia, Federico Polverino, Massimiliano Creta, Nicola Longo, Ciro Imbimbo, Enrico Checcucci, Stefano Puliatti, Paolo Dell'oglio, Gianluigi Califano
{"title":"A systematic review assessing the reliability of studies focusing on urological content on YouTube.","authors":"Claudia Collà Ruvolo, Simone Morra, Francesco Di Bello, Simone Cilio, Agostino Fraia, Federico Polverino, Massimiliano Creta, Nicola Longo, Ciro Imbimbo, Enrico Checcucci, Stefano Puliatti, Paolo Dell'oglio, Gianluigi Califano","doi":"10.23736/S2724-6051.24.05994-9","DOIUrl":"https://doi.org/10.23736/S2724-6051.24.05994-9","url":null,"abstract":"<p><strong>Introduction: </strong>In recent years, several publications have focused on analyzing the quality of medical content on YouTube. The current systematic review aimed to summarize and analyze the available studies examining YouTube video content in the urological field.</p><p><strong>Evidence acquisition: </strong>This is a systematic review including studies examining urological content uploaded on the YouTube platform published before November 2023. The following keywords were combined to capture relevant publications with a title/abstract search: (\"Urology\" OR \"Andrology\") AND (\"YouTube\" OR \"Social media\").</p><p><strong>Evidence synthesis: </strong>According to the inclusion criteria, 84 studies were included. Of all, 74 (88%) studies were published after the COVID-19 pandemic outbreak. A total of 52 (62%) studies used the DISCERN score, 29 (35%) the PEMAT A/V score, 30 (36%) the GQS, 23 (27%) the Misinformation score, 14 (17%) the Likert scale, and 13 (15%) the JAMA score. According to the conclusion, 62 (74%) studies reported poor quality results. Among all, only 10 (12%) studies respected our criteria of best quality methodology, defined as: 1) description of the research time frame; 2) use of incognito status; 3) the description of the inter-rater variability between reviewers; 4) use of at least one quality assessment tool.</p><p><strong>Conclusions: </strong>The systematic review highlights significant variability in results and methodologies across studies on the quality analysis of urological content on YouTube. The official urological community should establish guidelines for authors, aiming to enhance the reliability and importance of such publications as valuable resources for daily clinical practice.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"192-201"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Which improvements does Rezum bring to BPH management? A network meta-analysis and comparison of water vapor therapy and conduction ablation techniques.","authors":"Yun-Jung Yang, Eun-Jung Yang, Tuan T Nguyen, Taiki Kato, Se-Young Choi","doi":"10.23736/S2724-6051.25.06109-9","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06109-9","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluated the effectiveness and safety of Rezum water vapor thermal therapy (Rezum) and compared them with those of traditional conduction ablation methods for the management of benign prostatic hyperplasia.</p><p><strong>Evidence acquisition: </strong>A comprehensive review of studies from the PubMed, Cochrane, and EMBASE databases was performed. Only randomized clinical trials that reported the outcomes of thermal ablation treatments, including transurethral microwave therapy (TUMT), transurethral needle ablation (TUNA), and Rezum, were included. A network meta-analysis was performed to compare these treatments.</p><p><strong>Evidence synthesis: </strong>Sixteen studies comprising 1622 patients were included. Rezum did not show efficacy superior to that of traditional conduction ablation methods in terms of the International Prostate Symptom Score, quality of life, peak urinary flow rate, and postvoid residual volume. The incidence of acute urinary retention associated with Rezum was similar to that associated with other conduction ablation methods of TUMT and TUNA and transurethral resection of the prostate. Regarding ejaculatory dysfunction, Rezum resulted in outcomes comparable to those of sham treatment. According to the surface under the cumulative ranking curve, Rezum resulted in the lowest incidence of ejaculatory dysfunction.</p><p><strong>Conclusions: </strong>Rezum provides functional outcomes of urinary symptoms that are comparable to those of conduction ablation therapies. Notably, among the minimally invasive thermal ablation therapies evaluated during this study, Rezum resulted in the lowest incidence of ejaculatory dysfunction.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 2","pages":"171-180"},"PeriodicalIF":4.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143995594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}