Minerva Urology and Nephrology最新文献

{"title":"The future of BPH treatment: is a new paradigm at our doorstep?","authors":"Paolo Geretto, Sabrina DE Cillis, Mikolaj Przydacz","doi":"10.23736/S2724-6051.24.06294-3","DOIUrl":"https://doi.org/10.23736/S2724-6051.24.06294-3","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary tract infection as a leading cause of morbidity after radical cystectomy: unveiling microbiological patterns and risk factors.","authors":"Alberto Artiles Medina, José D Subiela Henríquez, Alfonso Muriel García, César Mínguez Ojeda, Álvaro Sánchez González, Irene DE LA Parra Sánchez, David López Curtis, Victoria Gómez Dos Santos, Miguel Á Jiménez Cidre, Francisco J Burgos Revilla","doi":"10.23736/S2724-6051.24.06171-8","DOIUrl":"10.23736/S2724-6051.24.06171-8","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"144-147"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robot-assisted video-endoscopic inguinal lymphadenectomy with the Hugo™ RAS System: surgical set-up and initial experience.","authors":"Josep M Gaya, Camille Berquin, Giuseppe Basile, Alessio Pecoraro, Andrea Gallioli, Isabel Sanz Gomez, Paula Izquierdo, Angelo Territo, Pavel Gavrilov, Joan Palou, Antonio Rosales, Alberto Breda","doi":"10.23736/S2724-6051.24.06044-0","DOIUrl":"https://doi.org/10.23736/S2724-6051.24.06044-0","url":null,"abstract":"<p><strong>Background: </strong>The Hugo^™ RAS system is gaining prominence in the field of urologic robotic surgery. To date, no study has described robot-assisted video-endoscopic inguinal lymphadenectomy (RAVEIL) using this system. Therefore, the aim of the study is to evaluate the feasibility and safety of the procedure, focusing on surgical set-up and preliminary results.</p><p><strong>Methods: </strong>A total of seven procedures in five patients with penile cancer were prospectively included. Baseline patient characteristics, intra- and post-operative surgical outcomes were recorded.</p><p><strong>Results: </strong>Overall, four patients (80%) had negative clinical N-staging (cN0). Median (IQR) operative time was 90 (85-97.5) minutes, with a median (IQR) of 8 (8-9) lymph node yield per procedure. One post-operative complication, a lymphocele requiring percutaneous drainage (Clavien-Dindo 3a), was reported. Median (IQR) hospital stay was 3 (3-3.5) days and the median (IQR) time to drain removal was 8 (6.5-10) days.</p><p><strong>Conclusions: </strong>This is the first case series demonstrating the safety and feasibility of RAVEIL using the Hugo^™ RAS system. The surgical configuration described may serve as a valuable reference standard for RAVEIL with this robotic platform and help novel adopters in implementing the platform in another surgical scenario.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 1","pages":"79-84"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confocal microscopy for immediate analysis of prostate biopsies.","authors":"Cristian Rodríguez Concha, Pedro DE Pablos-Rodríguez, Ana Calatrava Fons, Jessica Aliaga Patiño, Paula Pelechano Gómez, María I Martín García, Juan Boronat Catalá, Álvaro Gómez-Ferrer Lozano, Manuel Beamud Cortés, Ángel García Cortés, Augusto Wong Gutiérrez, José A López González, Argimiro Collado Serra, José L Domínguez-Escrig, Mario Hassi Román, Juan Casanova Ramón-Borja","doi":"10.23736/S2724-6051.25.06102-6","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06102-6","url":null,"abstract":"<p><strong>Background: </strong>Diagnosis of prostate cancer (PC) is based on haematoxylin-eosin (HE) staining, time-consuming, histopathological evaluation. Fluorescent confocal microscopy (FCM) allows tissue analysis at the same time as sample collection. The aim of this paper was to evaluate concordance between HE and FCM, and the additional value of a second pathologist.</p><p><strong>Methods: </strong>Two hundred ninety-seven magnetic resonance imaging-targeted prostate biopsy cores from 95 region of interest (ROI) were intraoperatively analyzed using FCM (VivaScope), and subsequently sent for conventional HE examination. A positive or negative diagnose was made by two pathologists on FCM. Additionally, the agreement of the International Society of Uropathology (ISUP) grade was evaluated. Agreement between FCM and HE analysis in terms of the presence/absence of PC was analyzed at ROI level. Concordance between two different pathologists was evaluated. If one pathologist considered the ROI with suspected PC and the other disagreed, it was categorized as absence of PC.</p><p><strong>Results: </strong>FCM allowed intraoperative assessment with strong histopathological evaluation agreement. Cohen's Kappa to detecting PC was 0.79 for pathologist 1 (P1), 0.81 for pathologist 2 (P2), and 0.85 for combined pathologists (P1-P2). Positive predictive values for P1, P2 and P1-P2 were 89%, 86% and 100%, respectively. Negative predictive values for P1, P2 and P1-P2 were 90.7%, 95.5 and 86.5%, respectively. Cohen's Kappa concordance for ISUP 1-2 detection was 0.7 for P1, 0.8 for P2 and 0.85 for P1-P2, and for ISUP 3-5, it was 0.69 for P1, 1 for P2 and 1 for P1-P2.</p><p><strong>Conclusions: </strong>FCM allowed rapid and accurate evaluation of prostate biopsy with a good correlation between two pathologists.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 1","pages":"85-90"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mini-percutaneous nephrolithotomy using the new Cyber Ho generator with Magneto technology: the first clinical experience in the treatment of renal stones between 10 and 20 mm.","authors":"Davide Perri, Umberto Besana, Federica Mazzoleni, Matteo Maltagliati, Andrea Pacchetti, Tommaso Calcagnile, Giorgio Bozzini","doi":"10.23736/S2724-6051.24.06286-4","DOIUrl":"10.23736/S2724-6051.24.06286-4","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"140-142"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lower PHI, [-2]proPSA/fPSA and testosterone/estradiol ratios in healthy black men: preliminary results and potential implications in prostate cancer clinical management.","authors":"Matteo Ferro, Ottavio De Cobelli, Felice Crocetto, Gianluigi Carbone, Benito F Mirto, Mariano Fiorenza, Alfonso Falcone, Evelina La Civita, Giuseppe Fallara, Gennaro Musi, Bernardo Rocco, Cristian Fiori, Francesco Porpiglia, Daniela Terracciano","doi":"10.23736/S2724-6051.24.05667-2","DOIUrl":"10.23736/S2724-6051.24.05667-2","url":null,"abstract":"<p><strong>Background: </strong>Black men residing in Western countries are more likely to develop prostate cancer (PCa), have higher mortality and are younger than the general population at initial diagnosis. In addition to genetic and environmental factors, the reasons for these racial disparities can also be attributed to social determinants of health such as low health literacy of this population and poor awareness of health services. Little is known about laboratory tests for PCa in black men.</p><p><strong>Methods: </strong>In this preliminary study. we investigated whether ethnicity affect PSA molecular forms, PHI, estradiol and testosterone levels in healthy men.</p><p><strong>Results: </strong>We found that healthy black men had lower PHI, [-2]proPSA/fPSA and testosterone/estradiol ratios.</p><p><strong>Conclusions: </strong>Our findings even if on a small study population could have a relevant clinical impact. since PCa screening is particularly relevant in black men who are at high risk of clinically significant PCa. PSA-based screening is needed and overdiagnosis must be avoided. Our findings could be particularly impactful. Future research on larger population needs to consider whether ethnicity specific laboratory tests thresholds could help to reduce the ethnic inequalities in prostate cancer diagnosis.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"52-56"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should every randomized controlled trial be considered Level 1 evidence?","authors":"Bernardo Rocco, Maria C Sighinolfi, Alessandro Antonelli, Andrea Minervini, Vipul Patel, Rafael Coelho, Marcio Covas Moschovas, Michele Amenta, Filippo Annino, Riccardo Bertolo, Marco Borghesi, Pierluigi Bove, Giorgio Bozzini, Giovanni Cacciamani, Antonio Celia, Carlo Ceruti, Orietta Dalpiaz, Roberto Falabella, Mario Falsaperla, Antonio Galfano, Fabrizio Gallo, Francesco Greco, Paolo Parma, Antonio Pastore, Giovanni Pini, Angelo Porreca, Carmine Sciorio, Riccardo Schiavina, Silvia Secco, Tommaso Silvestri, Virginia Varca, Domenico Veneziano, Paolo Verze, Alessandro Volpe, Stefano Zaramella, Marco Sandri, Cristian Fiori, Luigi Schips, Francesco Porpiglia","doi":"10.23736/S2724-6051.25.06422-5","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06422-5","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 1","pages":"137-139"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review and meta-analysis of the impact of preoperative surgical planning in robotic-assisted radical prostatectomy on trifecta outcomes.","authors":"Elizabeth Day, Lazaros Tzelves, Louise Dickinson, Greg Shaw, Zafer Tandogdu","doi":"10.23736/S2724-6051.25.06144-0","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06144-0","url":null,"abstract":"<p><strong>Introduction: </strong>Surgical planning in robotic assisted radical prostatectomy (RARP) recommends the maximal use of function persevering techniques without compromising oncological outcomes. There is no consensus on how to define the optimal surgical approach. This review aims to collate available evidence on the impact of preoperative planning interventions on the trifecta of oncological, functional or operative outcomes.</p><p><strong>Evidence acquisition: </strong>A systematic review according to the PRISMA guidelines was performed using the terms ((prostatectomy) AND (robot*)) AND (plan*) OR (image*) OR (decision*) for articles published between January 2000 and January 2024. Prospective studies reporting patients undergoing RARP with a preoperative planning intervention, compared to no planning, to determine at least one of trifecta outcome were included. Results were synthesized in a narrative review with a metanalysis when two or more studies reported the same outcomes.</p><p><strong>Evidence synthesis: </strong>Eight studies, one RCT and seven non-randomised prospective comparative studies, including 1945 patients, applying clinical nomograms, MRI and histology review were included. The outcomes reported were positive surgical margins (PSM) (oncological) and nerves sparing rates (functional). No operative outcomes were reported. Metanalysis demonstrated that positive surgical margins (PSM) were reduced in both clinical nomogram (RR=0.56, 95% CI: 0.37-0.87, P=0.009; two studies 563 patients) and MRI (RR=0.72, 95% CI: 0.54-0.96, P=0.02; three studies, 801 patients) intervention groups. Additionally, metanalysis of all nerve-sparing cases demonstrated lower PSM rates in the intervention group (RR=0.65, 95% CI: 0.47-0.90, P=0.01; three studies, 823 patients). No significant changes were seen in nerve-sparing rates.</p><p><strong>Conclusions: </strong>Preoperative surgical planning with nomograms and MRI has the potential to improve PSM rates without compromising nerve sparing. It is not possible to identify the optimal approach, but it is likely that the incorporation of biopsy and MRI information will lead to the best outcomes. Further studies using universally accepted standards of the trifecta outcomes are needed.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 1","pages":"25-32"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The necessity of open surgery experience for robotic surgeons.","authors":"Giampaolo Bianchi, Stefano Puliatti, Natali Rodriguez Peñaranda","doi":"10.23736/S2724-6051.25.06423-7","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06423-7","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"77 1","pages":"1-2"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robot-assisted retroperitoneoscopic kidney surgery with Versius®.","authors":"Fabrizio Dal Moro, Simonetta Fracalanza, Fabio Zattoni, Giacomo Novara, Mario Gardi","doi":"10.23736/S2724-6051.24.06122-6","DOIUrl":"10.23736/S2724-6051.24.06122-6","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"142-144"},"PeriodicalIF":4.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}