Minerva Urology and Nephrology最新文献

{"title":"YAU - RCC Spotlight: a call to action in the evolving field of renal cell carcinoma epidemiology.","authors":"Chiara Re, Riccardo Campi, Daniele Amparore","doi":"10.23736/S2724-6051.26.07102-8","DOIUrl":"https://doi.org/10.23736/S2724-6051.26.07102-8","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The old standard still holds up: reading CREST, POTOMAC, and ALBAN in BCG-naive high-risk non-muscle-invasive bladder cancer.","authors":"Andrea Mari, Luca Lambertini, Simone Albisinni, Roberto Contieri, Riccardo Bertolo, Francesco Soria","doi":"10.23736/S2724-6051.26.07132-6","DOIUrl":"https://doi.org/10.23736/S2724-6051.26.07132-6","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148303999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tailoring the right \"MIST\" for the right patient.","authors":"Riccardo G Bertolo, Francesco Ditonno, Lorenzo Bianchi, Roberto Contieri, Elisa DE Lorenzis, Pietro Piazza, Andrea Mari","doi":"10.23736/S2724-6051.26.07117-X","DOIUrl":"https://doi.org/10.23736/S2724-6051.26.07117-X","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148279959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"YAU-RCC spotlight: randomized controlled trials in renal surgery. Lessons from ROBOCOP II and OpeRa.","authors":"Savio D Pandolfo, Daniele Amparore, Zhenjie Wu, Riccardo Campi","doi":"10.23736/S2724-6051.26.07064-3","DOIUrl":"https://doi.org/10.23736/S2724-6051.26.07064-3","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148280001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking first-line therapy in overactive bladder: is it time for a paradigm shift?","authors":"Eleonora Rosato, Francesco Esperto, Michele Marchioni, Stefano Puliatti, Fabio Zattoni, Simone Albisinni","doi":"10.23736/S2724-6051.26.07116-8","DOIUrl":"https://doi.org/10.23736/S2724-6051.26.07116-8","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":""},"PeriodicalIF":5.1,"publicationDate":"2026-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148279945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is orthotopic neobladder truly a urinary diversion? Revisiting post-cystectomy terminology.","authors":"Francesco Esperto, Rocco Papalia, Arianna Pischetola, Roberto M Scarpa","doi":"10.23736/S2724-6051.26.07041-2","DOIUrl":"https://doi.org/10.23736/S2724-6051.26.07041-2","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"78 3","pages":"316-318"},"PeriodicalIF":5.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148430782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative safety and short-term survival outcomes of radical nephrectomy with thrombectomy in geriatric renal cell carcinoma patients with venous tumor thrombus.","authors":"Yunhe Guan, Peng Hong, Ruotao Xiao, Shiying Tang, Zhuo Liu, Xiaojun Tian, Guoliang Wang, Lulin Ma, Hongxian Zhang, Shudong Zhang","doi":"10.23736/S2724-6051.26.06676-0","DOIUrl":"https://doi.org/10.23736/S2724-6051.26.06676-0","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to evaluate the feasibility and safety of radical nephrectomy with thrombectomy for geriatric renal cell carcinoma (RCC) patients with venous tumor thrombus (VTT).</p><p><strong>Methods: </strong>The retrospective analysis included 542 patients with RCC and VTT between 2014 and 2024. Patients were stratified into geriatric (≥70 years, N.=88) and younger groups (<70 years, N.=454). Propensity score matching (PSM, 1:1) balanced baseline variables, including Mayo classification, TNM stage, surgical approach, and comorbidities. Perioperative outcomes (operative time, blood loss, complications) and 1-year survival rates were compared.</p><p><strong>Results: </strong>Geriatric patients exhibited higher comorbidity rates (82.95% vs. 64.54%, P=0.001) and ≥3 ASA scores portion (26.14% vs. 14.10%, P=0.004) but shorter tumor diameter (7.9 cm vs. 8.8 cm, P=0.007). After PSM, perioperative outcomes showed no significant difference: operative time (271 vs. 290 min, P=0.14), blood loss (400 vs. 600 mL, P=0.23), complications (37.50% vs. 40.97%, P=0.53) or severe complications (8.0% vs. 9.2%, P=0.67). 1-year overall survival was similar between two groups (94.6% vs. 94.1%, HR=1.04, P=0.90), as was cancer-specific survival (HR=0.98, P=0.96). For the inferior vena cava VTT and M0 stage subgroups, the outcomes were consistent with the above.</p><p><strong>Conclusions: </strong>This study demonstrates comparable perioperative safety and equivalent short-term survival benefits between geriatric and younger patients undergoing radical nephrectomy with thrombectomy, regardless of VTT complexity and distant metastasis. Age alone should not preclude surgical intervention when supported by comprehensive multidisciplinary assessment.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"78 3","pages":"352-362"},"PeriodicalIF":5.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary results of endoscopic ablation of upper tract urothelial carcinoma using the Ho:YAG laser with Magneto technology: assessment of efficacy and safety in the short-term.","authors":"Davide Perri, Umberto Besana, Giovannalberto Pini, Eugenio Ventimiglia, Otas Durutovic, Giorgio Bozzini","doi":"10.23736/S2724-6051.25.06816-8","DOIUrl":"https://doi.org/10.23736/S2724-6051.25.06816-8","url":null,"abstract":"","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"78 3","pages":"441-443"},"PeriodicalIF":5.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148431093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Off-clamp and on-clamp robotic-assisted partial nephrectomy in ischemia-sensitive patients: a multicenter propensity score-matched study (RAPN OFF-CLAMP study - UroCCR 187).","authors":"Léo Schurdi-Levraud, Gaëlle Margue, Arna Geshkovska, Karim Bensalah, Coline Ricolleau, Franck Bruyere, Cécile Champy, Constance Michel, Louis Surlemont, Jean-Christophe Fantoni, Alexis Fontenil, Clément Sarrazin, Jean-Baptiste Beauval, Bastien Parier, Frédéric Panthier, Jean-Jacques Patard, Olivier Belas, Pierre Bigot, Jean-Christophe Bernhard","doi":"10.23736/S2724-6051.26.06819-9","DOIUrl":"10.23736/S2724-6051.26.06819-9","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to assess the real impact of ischemia during robotic-assisted partial nephrectomy (RAPN) in high-risk patients, this study focused on ischemia-sensitive populations such as those with a solitary kidney (SK) or chronic kidney disease (CKD), who may benefit from off-clamp (OfC) nephron-sparing surgery.</p><p><strong>Methods: </strong>We retrospectively analyzed all RAPN cases performed at 16 centers of the UroCCR network (2011-2024), in patients with a SK or stage 3b CKD (eGFR≤45 mL/min/m²). Patients were prospectively enrolled in the UroCCR project after signed consent. Our cohort was divided into two subgroups of SK and CKD. A propensity score matching adjusted on preoperative eGFR and RENAL score was used in SK subgroup and on baseline creatinine in CKD subgroup. We compared OfC RAPN and on-clamp RAPN (OnC) in terms of perioperative outcomes. Our main objective was to assess post-operative evolution of renal function.</p><p><strong>Results: </strong>Among 251 RAPN, 144 were performed OnC and 107 OfC. After matching, OfC SK had less eGFR variation between pre-operative level and day 1 (-19.5 vs. -27.6 mL/min/1.73 m²; P=0.001) or discharge (-6.7 vs. -15.0 mL/min/1.73 m²; P=0.001). This difference was no longer observed beyond 3 months. SK operated OfC presented less AKI at day 1 and at discharge (67.6% vs. 86.8%; P=0.01). They were discharged significantly more often at D0/D1, with a lower length of stay (3.4 vs. 6.4 days; P=0.001). There was no significant difference in terms of complications, bleeding, locoregional recurrence and positive margins. We found no significant difference in the CKD subgroup.</p><p><strong>Conclusions: </strong>OfC RAPN offers significant short-term functional advantages in ischemia-sensitive patients with a solitary kidney. By avoiding warm ischemia, the OfC approach reduces the incidence of acute kidney injury and shortens hospital stays, without increasing surgical morbidity or compromising oncologic outcomes.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":"78 3","pages":"373-382"},"PeriodicalIF":5.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148430933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platelet-rich plasma injections for the treatment of Peyronie's disease: a systematic review of contemporary literature with mixed-effects model analysis of penile curvature outcome.","authors":"Andrea Panunzio, Rossella Orlando, Maria V D'Agostino, Federico Greco, Antonio B Porcaro, Alessandro Antonelli, Filippo Migliorini, Antonio Vitarelli, Michele Battaglia, Leonardo Bizzotto, Alessandro Tafuri","doi":"10.23736/S2724-6051.25.06591-7","DOIUrl":"10.23736/S2724-6051.25.06591-7","url":null,"abstract":"<p><strong>Background: </strong>To provide an updated and detailed overview of the current use of platelet-rich plasma (PRP) penile injections in men affected by Peyronie's disease (PD).</p><p><strong>Methods: </strong>A comprehensive search in PubMed, Scopus, and Web of Science, was performed for prospective and retrospective, single cohort or comparative studies published in form of full-text articles or conference abstracts, evaluating safety and efficacy of PRP for PD treatment. Primary outcome consisted in the reduction of penile curvature. Sexual function and adverse/side effects were also investigated. Qualitative and quantitative data syntheses were provided.</p><p><strong>Results: </strong>Overall, 15 records were included: four studies focused on PRP alone, two randomized clinical trials tested PRP versus placebo, and the remainder assessed the combination of PRP with external shock wave therapy, manual penile modelling, vacuum erection device therapy, percutaneous needle tunneling, phosphodiesterase type-5 inhibitors or hyaluronic acid. Patient numbers ranged between 10 and 159 according to studies, with 685 patients receiving PRP alone or in combination (median age 56.2 years). Despite the heterogeneity in study design, protocol of administration, dose of PRP, and follow-up duration, all studies independently reported a statistically significant improvement in penile curvature and sexual outcomes, without major adverse/side effects. A linear mixed-effects model was fitted to estimate the change in penile curvature over time across studies, with results suggesting that the effect of PRP on reducing penile curvature tends to improve over time, was enhanced by greater initial treatment intensity, and negatively influenced by patient age.</p><p><strong>Conclusions: </strong>PRP penile injections for PD treatment have shown encouraging results in preliminary studies. Patient numbers and the short-term follow-up may limit the generalizability of these observations. High-quality, large-scale, and standardized controlled trials are needed before starting to recommend its use in clinical practice.</p>","PeriodicalId":53228,"journal":{"name":"Minerva Urology and Nephrology","volume":" ","pages":"323-334"},"PeriodicalIF":5.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146004653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}