Journal of Affective Disorders Reports最新文献

{"title":"Lithium reduces impulsive decision making in transdiagnostic patients at high risk for suicide attempt recurrence: A randomized, double blind, placebo-controlled, crossover study","authors":"Nicholas Murphy ,&nbsp;Grace Pham ,&nbsp;Andreas Weyland ,&nbsp;Julia Engelhardt ,&nbsp;George Kypriotakis ,&nbsp;Ynhi T. Thomas ,&nbsp;Thomas R. Kosten ,&nbsp;Nidal Moukaddam ,&nbsp;Sanjay J. Mathew ,&nbsp;Alan C. Swann","doi":"10.1016/j.jadr.2024.100833","DOIUrl":"10.1016/j.jadr.2024.100833","url":null,"abstract":"<div><h3>Background</h3><p>Studies attempting to distinguish suicide attempters from ideators have found that impulsivity is consistently associated with attempts across the spectrum of suicidal behavior from self-harm to lethal suicidal behavior. Impulsivity is readily assessed using complementary clinical and laboratory measures, making it a viable target for pharmacological strategies to prevent suicide risk. Lithium reduces suicidal behavior across diagnoses, and has been implicated in the reduction of impulsivity triggered by stress mediated phosphatidylinositol turnover. We used a placebo controlled cross-over design to study the effects of repeated lithium dosing on risk factors predisposing to suicidal behavior.</p></div><div><h3>Methods</h3><p>15 patients with a recent (past year) medically severe suicide attempt (MSSA) (37.5% male, 40.13 ± 13.66 years) received lithium carbonate and matching pill placebo separately in a randomized double-blind crossover design administered six weeks apart. To test the effect of lithium on measures of impulsivity and arousal, participants completed the Immediate Memory Task (IMT), Internal State Scale (ISS), and the Time Perception Task (TPT). We conducted separate analyses for each variable using repeated measures analysis of covariance.</p></div><div><h3>Results</h3><p>Lithium dosing was associated with increased IMT response latency (<em>p</em> <em>=</em> <em>.017, pη²</em> <em>=</em> <em>0.23),</em> and decision bias (<em>p</em> <em>=</em> .048, pη2 <em>=</em> 0.21). Lithium did not significantly alter time perception or activation.</p></div><div><h3>Conclusions</h3><p>Our results suggest that lithium may reduce risk in MSSA survivors by increasing the response latency and increasing conservative response bias during decision-making. Future studies should conduct long-term follow-ups with adjunct behavioral therapy with lithium on factors contributing to suicidal behavior.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100833"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666915324001197/pdfft?md5=8f5da84070c07a9fa8660654f2afc156&pid=1-s2.0-S2666915324001197-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142058450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of early maladaptive schemas in late adolescents suffering from school burnout and depressive symptoms","authors":"Annelies Van Royen,&nbsp;Laura Wante,&nbsp;Caroline Braet","doi":"10.1016/j.jadr.2024.100815","DOIUrl":"https://doi.org/10.1016/j.jadr.2024.100815","url":null,"abstract":"<div><h3>Background</h3><p>The present study aims to distinguish school burnout from depressive symptoms in late adolescents between 17 and 21 years old by exploring their underlying early maladaptive schemas (EMS).</p></div><div><h3>Methods</h3><p>The cross-sectional sample (T1) consisted of 514 secondary and higher education students between 17 and 21 years old (<em>M</em>_age = 19.06 (1.10), 80.9% female). Five months later (T2), 190 adolescents participated in the follow-up measurement (<em>M</em>_age = 19.45 (1.18), 81.6% female).</p></div><div><h3>Results</h3><p>Positive correlations were found between all EMS and school burnout symptoms. When controlling for school burnout symptoms at T1, only the EMS `emotional deprivation', `mistrust', `defectiveness', `social isolation', `failure', `enmeshment', and `emotional inhibition' displayed significant positive associations with school burnout at T2. The EMS `mistrust', `defectiveness' and `failure' showed relations to both school burnout and depressive symptoms. Backwards linear regressions showed that the EMS `vulnerability to harm/illness' and `insufficient self-control' were uniquely related to school burnout symptoms when controlling for depressive symptoms, while the EMS `dependence', `emotional deprivation', `self-sacrifice' and `unrelenting standards' were uniquely related to depressive symptoms while controlling for school burnout symptoms.</p></div><div><h3>Limitations</h3><p>The gender-unbalanced sample, reduced longitudinal sample size, sole use of self-report measures, and high comorbidity between school burnout and depressive symptoms may have hampered the results.</p></div><div><h3>Conclusions</h3><p>EMS play an important role in the development of school burnout symptoms. The results point towards transdiagnostic cognitive-focused treatment techniques with attention to disorder-specific schemas to tackle school burnout symptoms. More (longitudinal) research is needed to corroborate these initial findings.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100815"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S266691532400101X/pdfft?md5=a8e0942cb1f6708094b141bac32f1053&pid=1-s2.0-S266691532400101X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141479565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The chain mediating role of stress and resilience in the relationship between anxiety sensitivity and depressive symptoms among Chinese college students","authors":"Mengjie Cui ,&nbsp;Xia Ma ,&nbsp;Liyuan Tian ,&nbsp;Wenfeng Xu ,&nbsp;Hongliang Dai","doi":"10.1016/j.jadr.2024.100821","DOIUrl":"10.1016/j.jadr.2024.100821","url":null,"abstract":"<div><h3>Background</h3><p>College is a high-risk period for depressive symptoms. Anxiety sensitivity (AS) is a major predictor of depressive symptoms during college years, but the specific mechanisms remain unclear. This study investigated the relationship using a chain mediation model.</p></div><div><h3>Methods</h3><p>A sample of 1261 eligible students (mean age of 20.20 ± 1.37 years) residing in Liaoning Province, located in the northeastern part of China, were selected through a convenient sampling method for the purpose of carrying out a comprehensive survey. The self-report questionnaires used in the study encompassed a range of parameters, including the general information questionnaire, anxiety sensitivity index-3 (ASI-3), resilience scale-14 (RS-14), depression, anxiety, and stress scale (DASS-21). Pearson correlation analysis, structural equation model testing, and Bootstrap deviation correction percentile analysis were employed to analyze the survey data using the R 4.3.2 statistical software.</p></div><div><h3>Results</h3><p>The total AS score and its three lower-order dimensions were positively correlated with stress and depressive symptoms. Resilience was negatively correlated with AS, stress and depressive symptoms. In addition to the direct influence of AS on depressive symptoms, stress and resilience play a partial mediating role in the relationship between AS physical and cognitive concerns and depressive symptoms, the total indirect effects accounted for 91.5 % and 92.1 %, respectively, and fully mediate the relationship between AS social concerns and depressive symptoms.</p></div><div><h3>Conclusions</h3><p>The study's outcomes indicate that practical actions can be taken to decrease AS and stress, thereby enhancing resilience and reducing depressive symptoms in adolescents.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100821"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666915324001070/pdfft?md5=c912639d954bf56da2bfebf9fe8daadc&pid=1-s2.0-S2666915324001070-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141637926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the relationship between lifestyle factors and mental health outcomes among Afghan university students","authors":"Ali Rahimi ,&nbsp;Mohammad Faisal Wardak ,&nbsp;Nasar Ahmad Shayan","doi":"10.1016/j.jadr.2024.100827","DOIUrl":"10.1016/j.jadr.2024.100827","url":null,"abstract":"<div><h3>Background</h3><p>Lifestyle factors such as physical activity, diet, and sleep can impact university students' mental health. This study examined the associations between lifestyle and mental health among students at Herat University in Afghanistan.</p></div><div><h3>Methods</h3><p>A cross-sectional study was conducted among 677 students selected through stratified random sampling. Participants completed a questionnaire on socio-demographics, physical health, dietary habits, and the Depression Anxiety Stress Scale (DASS-42). Chi-square tests and logistic regression analyzed the relationships between lifestyle factors and DASS-42 scores.</p></div><div><h3>Results</h3><p>Poor perceived health and irregular breakfast consumption were associated with higher odds of depression and anxiety. Low vegetable intake also increases the odds of depression and anxiety. Studying non-medical fields and irregular sleep patterns were linked to higher stress levels.</p></div><div><h3>Conclusion</h3><p>Comprehensive health promotion and targeted interventions addressing dietary habits, sleep, and discipline-specific needs may improve the mental well-being of university students. A multidimensional approach is required to foster a healthy campus environment.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100827"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666915324001136/pdfft?md5=0adbdf59b509335480bb61a9cdd7591a&pid=1-s2.0-S2666915324001136-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142011096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-poisoning evaluated in the emergency department of a general hospital in the years 2014–2020 and the provision of psychiatric services before and after the index event","authors":"Cesare Turrina ,&nbsp;Lorenzo Silva ,&nbsp;Daria Bettoni ,&nbsp;Ciro Paolillo ,&nbsp;Tullio Elia Testa ,&nbsp;Antonio Vita","doi":"10.1016/j.jadr.2024.100835","DOIUrl":"10.1016/j.jadr.2024.100835","url":null,"abstract":"<div><h3>Background</h3><p>The recent literature on self-poisoning (SP) has mainly focused on the type of substances used for SP and the associated variables. Few data are available on psychiatric diagnoses, repeated SP, multiple substances SP, contacts with psychiatric services before the event and after a long follow-up.</p></div><div><h3>Methods</h3><p>A consecutive series of 1.807 subjects evaluated in the emergency department of a large urban university hospital was collected from 2014 to 2020. These subjects were matched with the data of Psyche-Web, a case register collecting all psychiatric contacts of the Lombardia Region, Italy.</p></div><div><h3>Results</h3><p>The most used drugs were benzodiazepines (37.8 %), cocaine (24.0 %), cannabis (15.2 %), antipsychotics (10.5 %), antidepressants (9.2 %). Alcohol was associated in 27.0 % of the cases. The most frequent psychiatric diagnoses were substance use (28.8 %), personality disorders (24.5 %), and mood disorders (21.7 %). Subjects who repeatedly self-poisoned were younger, more often suffered from a personality disorder and less often from a substance use disorder. In 38.2 % of the sample SP was the first-time presentation to psychiatric evaluation of a mood, personality, or psychotic disorder. At one-year follow-up 63.3 % were not in contact with psychiatric services.</p></div><div><h3>Limitations</h3><p>This study could not include children and adolescents because Psyche-Web stores data only for the adult population. Psychiatric diagnoses were given by specialists, but in different settings.</p></div><div><h3>Conclusions</h3><p>A substantial number of subjects with no previous contacts remained out of the reach of psychiatric care after discharge. A subgroup of these patients would probably benefit of a more structured referral.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100835"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666915324001215/pdfft?md5=17f3b9460c0690923286b336df9c7328&pid=1-s2.0-S2666915324001215-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142050393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric examination and factorial validity of a German short form of the Beck Hopelessness Scale in three different samples","authors":"T. Forkmann ,&nbsp;J. Eimen ,&nbsp;L. Plein ,&nbsp;I. Höller ,&nbsp;L. Böhler ,&nbsp;A. Schönfelder ,&nbsp;N. Hallensleben ,&nbsp;D. Schreiber ,&nbsp;L. Paashaus ,&nbsp;G. Juckel ,&nbsp;T. Teismann ,&nbsp;H. Glaesmer ,&nbsp;L. Spangenberg","doi":"10.1016/j.jadr.2024.100822","DOIUrl":"10.1016/j.jadr.2024.100822","url":null,"abstract":"<div><h3>Background</h3><p>Hopelessness is a transdiagnostically relevant clinical construct, related to depression, post-traumatic stress disorder and suicidality. Economic, valid, and reliable assessment of hopelessness is thus crucial for both research and clinical practice. This study aimed at validating a nine-item short version of the Beck Hopelessness Scale in three large German samples of psychiatric inpatients, psychotherapy outpatients, and healthy controls.</p></div><div><h3>Methods</h3><p>Data from <em>N</em> = 2321 participants (86.3 % female, mean age 31.8 years [SD=10.4]) were used to analyze reliability, factorial validity, concurrent and discriminant validity of the BHS-9.</p></div><div><h3>Results</h3><p>Results showed good psychometric characteristics of the BHS-9 in inpatients, supporting its unidimensionality, construct validity, and reliability. However, factorial validity was insufficient in outpatients and controls.</p></div><div><h3>Limitations</h3><p>In the outpatient and control samples, the majority of participants were women. All reported analyses were cross-sectional.</p></div><div><h3>Conclusions</h3><p>The BHS-9 appears to be suitable for assessing hopelessness in psychiatric inpatients. However, the factorial validity of this short instrument in non-inpatient settings should be subject to future studies before its implementation in these person groups can be recommended.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100822"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666915324001082/pdfft?md5=ec3e5099887d6a0cd634185d23827135&pid=1-s2.0-S2666915324001082-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141702770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and risk factors for anxiety, stress and depression among higher education students in Portugal and Brazil","authors":"Carmona Laura ,&nbsp;Costa Carlos ,&nbsp;Gascón Santiago ,&nbsp;Ribeiro Graziela ,&nbsp;Chambel Maria José","doi":"10.1016/j.jadr.2024.100825","DOIUrl":"10.1016/j.jadr.2024.100825","url":null,"abstract":"<div><h3>Objective</h3><p>Determine the prevalence and risk factors for anxiety, stress and depression among higher education students in a sample from Portugal and Brazil.</p></div><div><h3>Methods</h3><p>Students from Portugal (<em>n</em> = 709) and Brazil (<em>n</em> = 487) answered the Depression, Anxiety and Stress Scale (DASS-21) and demographic and academic characteristics questions.</p></div><div><h3>Results</h3><p>Rates of anxiety, stress, and depression were 55.3 %, 55.9 % and 56.3 % for Portuguese students and 71.5 %, 75.6 % and 68.2 % for Brazilian students, respectively. In the total sample, being Brazilian was found to predict anxiety, stress and depression. In both samples, being female was found to predict anxiety and stress. Being displaced was also found to affect mental health: anxiety for the Portuguese sample; stress for the Brazilian sample. Furthermore, in the Portuguese sample, fields of study were found to affect mental health: Education and Human Motricity protected from anxiety, stress and depression; Psychology protected from anxiety and depression; Medicine protected from depression. Non-working status was also found to predict depression in this sample.</p></div><div><h3>Limitations</h3><p>The cross-sectional design prevents the establishment of causal relationships; self-report measures may be susceptible to response bias; the recruitment of participants may be susceptible to selection bias; cultural factors and institutional differences between these countries may affect mental health.</p></div><div><h3>Conclusions</h3><p>Country, gender, displacement, field of study, and working status were found to affect higher education students’ mental health. From a clinical perspective, specific programs addressing anxiety, stress and depression in university students should be tested, as these disorders have a noteworthy prevalence in this population.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100825"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666915324001112/pdfft?md5=599c77923558c5f0ba777828eb765cbd&pid=1-s2.0-S2666915324001112-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141990988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moral distress as a persistent risk factor for impaired mental health among healthcare workforce","authors":"Alice Fattori ,&nbsp;Anna Comotti ,&nbsp;Paolo Brambilla ,&nbsp;Matteo Bonzini","doi":"10.1016/j.jadr.2024.100817","DOIUrl":"https://doi.org/10.1016/j.jadr.2024.100817","url":null,"abstract":"<div><h3>Background</h3><p>Moral distress among healthcare workers (HCWs) has dramatically increased during Covid-19 emergency however most evidence relies on cross-sectional data collected during Covid-19 early stages.</p></div><div><h3>Aims</h3><p>This longitudinal cohort study aims to provide a better insight into the occurrence and associations of moral distress, focusing on both its short and long-term impact on HCWs’ mental health.</p></div><div><h3>Methods</h3><p>A total of 990 healthcare workers completed a mental health evaluation between July 2020-July 2021 (Time 1) reporting frequencies of moral distress and psychological distress (GHQ-12), post-traumatic (IES-R) and anxiety (GAD-7) symptoms; after one year (July 2021-July 2022; Time 2), 310 participants repeated the psychological evaluation. We investigated differences considering socio-demographic and occupational characteristics. Two logistic regression models examined the potential role of moral distress as a risk factor for scorings above scales’ cut-offs at Time 1 and at Time 2.</p></div><div><h3>Results</h3><p>Frequent episodes of moral distress were mostly reported by nurses (24 %), physicians (22 %), younger workers (&lt;40y; 23 %) and workers engaged in Covid-19 area; HCWs from Emergency/Intensive Care Departments reported the highest occurrence of moral distress (29 %). Results showed increases in all psychological symptoms as episodes of moral distress became more frequent. Moral distress experienced at Time 1 resulted as a persistent risk for mental health impairment in the following year, with stable ORs for post-traumatic symptoms (Time1 OR=7.8, 95 %CI=(5.3,11.6) and Time2 OR=6.6, 95 %CI=(2.9,15.7).</p></div><div><h3>Conclusions</h3><p>Our findings support long-term consequences of moral distress; preventive strategies may be addressed with priority to younger HCWs and nurses/physicians from Emergency and Intensive Care Departments.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100817"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666915324001033/pdfft?md5=9ccc1451624253bf53dc9eb91914dbb4&pid=1-s2.0-S2666915324001033-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141595859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The continuum of recovery among Canadians with bipolar disorder: From remission to complete mental health","authors":"","doi":"10.1016/j.jadr.2024.100808","DOIUrl":"10.1016/j.jadr.2024.100808","url":null,"abstract":"<div><h3>Objectives</h3><p>Research on recovery from bipolar disorder focuses primarily on symptom remission and diagnostic criteria. Less attention, however, has been paid to other aspects of mental well-being and psychosocial functioning. The current study examines the prevalence of, and factors associated with, recovery from bipolar disorder through three levels: (1) remission from bipolar disorder; (2) the absence of psychiatric disorders (APD); and (3) complete mental health (CMH), which incorporates measures of happiness, life satisfaction, psychological flourishing, and absence of mental illness.</p></div><div><h3>Methods</h3><p>Data were drawn from the 2012 Canadian Community Health Survey-Mental Health. A subsample of 555 adults with bipolar disorder was analyzed using bivariate chi-square analyses and multivariate logistic regression models.</p></div><div><h3>Results</h3><p>Approximately 1 in 4 (23 %) participants with bipolar disorder achieved CMH, which was significantly lower than the 74 % of those without bipolar disorder who were in CMH. Factors associated with CMH among individuals with bipolar disorder included older age, higher household income, being married, having a confidant, utilizing religion or spirituality for coping, and being free from substance abuse or dependence and debilitating chronic pain.</p></div><div><h3>Limitations</h3><p>Absence of data on certain mental disorders, exclusion of hospitalized or unresponsive participants, and social desirability, may have biased the results.</p></div><div><h3>Conclusion</h3><p>By identifying factors associated with CMH among those with bipolar disorder, this study provides insight into recovery from bipolar disorder beyond symptom remission, highlights subpopulations who may be at heightened risk of further adverse mental health outcomes, and helps inform interventions that support recovery for individuals affected by bipolar disorder.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100808"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666915324000945/pdfft?md5=0e69d17453b581eeacd69c3ba8378cf7&pid=1-s2.0-S2666915324000945-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141392759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the effectiveness of transcranial direct current stimulation on improving cognitive function in bipolar patients","authors":"Ali Talaei ,&nbsp;Ali Akbari ,&nbsp;Mahdiyeh Sarraf-Razavi ,&nbsp;Shabnam Niroumand ,&nbsp;Dina Ganji ,&nbsp;Maryam Aghasizadeh ,&nbsp;Ali Azadmand ,&nbsp;Maryam Tayyebi-Meybodi ,&nbsp;Sanam Tayyebi-Meybodi","doi":"10.1016/j.jadr.2024.100818","DOIUrl":"10.1016/j.jadr.2024.100818","url":null,"abstract":"<div><h3>Background</h3><p>Bipolar disorder is classified as one of the most debilitating mental diseases. Although patients receive medical treatment, cognitive deficits remain in the euthymic phase in many patients. It is hypothesized that brain electrical stimulation protocols that increase cognitive function may increase the quality of life. Therefore, this study aimed to evaluate the effectiveness of transcranial direct current stimulation in improving cognitive function in bipolar patients in the euthymic phase.</p></div><div><h3>Methods &amp; Materials</h3><p>In a double-blind, sham-controlled- clinical trial, 46 euthymic bipolar patients diagnosed based on DSM-V were randomly divided into the two intervention and control groups. tDCS was applied for the intervention group using an anode electrode at the left dorsolateral-peripheral cortex (F3) and the cathode at the right dorsolateral-frontal (F4) (based on the 10/20 system) at 2 mA for 20 min. The Strop Color and Word Test, The Rey Auditory Verbal Learning Test (RAVLT), and The Wechsler Adult Intelligence Scale (WAISR) were evaluated before, at the end of the third and the seventh weeks of the intervention. Statistical analysis was performed using SPSS v 16.</p></div><div><h3>Results</h3><p>The scores of immediate and delayed auditory memory and visual memory in the intervention group, unlike the control group, improved significantly after treatment. Moreover, Wechsler's working memory score in the intervention group improved significantly after treatment. Consistent and inconsistent answers scores were also significantly improved in the intervention group compared with the controls.</p></div><div><h3>Conclusion</h3><p>The present study indicated that tDCS might be an efficient and safe method for improving cognitive function in euthymic bipolar patients.</p></div>","PeriodicalId":52768,"journal":{"name":"Journal of Affective Disorders Reports","volume":"17 ","pages":"Article 100818"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666915324001045/pdfft?md5=753c17b0b1b480d9d661050ba58253c0&pid=1-s2.0-S2666915324001045-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142095798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}