Revista Colombiana de Psiquiatria最新文献

{"title":"¿Se Podrá Recomendar el Tratamiento con Litio Para el Deterioro Cognitivo Leve y la Demencia por Enfermedad de Alzheimer? Falta Evidencia Sobre su Eficacia y su Seguridad: Revisión Sistemática y Metanálisis","authors":"","doi":"10.1016/j.rcp.2022.04.006","DOIUrl":"10.1016/j.rcp.2022.04.006","url":null,"abstract":"<div><h3>Introduction</h3><div>Alzheimer's disease is the most prevalent neurodegenerative disease worldwide. Currently available treatments are scarce and have modest effects. Lithium has been shown to decrease cognitive impairment in people with bipolar affective disorder. However, studies evaluating lithium for cognitive impairment in Alzheimer's disease remain controversial.</div></div><div><h3>Methods</h3><div>We conducted a systematic search of the literature using PubMed, EMBASE, the Cochrane Library, LILACS, and Google Scholar between 30 April and 10 May 2021. Randomised controlled clinical trials (RCTs) conducted to evaluate the efficacy and safety of lithium as a treatment for cognitive impairment in people with dementia and mild cognitive impairment due to Alzheimer's disease were included. The primary outcome was the difference in cognitive functioning at the end of the study. Two authors selected the studies and extracted the data. We calculated the standardised mean differences (SMD) for continuous variables and the relative risk (RR) for dichotomous variables. Review Manager 5.4 software was used for data processing.</div></div><div><h3>Results</h3><div>2,078 reports were identified and 3 studies with data from 248 participants were included. A fourth report was included for safety analysis. Compared to placebo, no significant difference was found in the cognitive performance of patients with mild cognitive impairment or dementia due to Alzheimer's disease receiving lithium treatment (SMD<!--> <!-->=<!--> <!-->–0.39; 95%<span>C</span>I, –0.82 to 0.04; I² <!-->=<!--> <!-->53%; n<!--> <!-->=<!--> <!-->195). Also, significant differences were not found in the rate of discontinuation for any cause (RR<!--> <!-->=<!--> <!-->0.90; 95%CI, 0.46-1.78; I² <!-->=<!--> <!-->0%), and the rate of adverse effects between lithium and placebo (RR<!--> <!-->=<!--> <!-->1.29; 95%CI, 0.83-2.03; I² <!-->=<!--> <!-->0%).</div></div><div><h3>Conclusions</h3><div>The current evidence is insufficient to assume any effect of lithium as a treatment for cognitive impairment in Alzheimer's disease dementia. It is necessary to continue building better quality studies to justify the use of lithium in this population in clinical practice. Given the toxicity of lithium, adequate pre-selection of patients and close monitoring should be ensured.</div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 327-339"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43599862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalencia y factores asociados al síndrome de burnout y engagement en estudiantes de ciencias de la salud en una universidad pública (2019)","authors":"","doi":"10.1016/j.rcp.2022.10.002","DOIUrl":"10.1016/j.rcp.2022.10.002","url":null,"abstract":"<div><h3>Objective</h3><div>To estimate the prevalence and factors associated with burnout syndrome and engagement in health sciences students at a public university in the different semesters of their career.</div></div><div><h3>Methods</h3><div>A cross-sectional study was carried out and included university students of health sciences. A stratified random sampling with proportional allocation was carried out. A descriptive analysis was carried out calculating frequencies, proportions and percentages, as well as measures of central tendency. The proportions of burnout and engagement were estimated with their corresponding 95% Confidence Interval (95% CI). For the bivariate analysis, the Chi² test was performed and a p value &lt;<!--> <!-->0.05 was considered statistically significant.</div></div><div><h3>Results</h3><div>314 students were included (220 undergraduate and 94 graduate) with a mean age of 25<!--> <!-->±<!--> <!-->5 years (18-48 years), 112 were men (35.7%) and 202 women (64.3%). The presence of burnout was detected in 26 students (8.3%, 95% CI 5.2-11.4%). 73.9% presented high levels of exhaustion. A lower percentage of classification between high, medium-high and very high was found in those with a job (p<!--> <!-->=<!--> <!-->0.02); and greater evidence of exhaustion (high and very high) in the medicine and postgraduate programs (p<!--> <!-->=<!--> <!-->0.01). There were no significant differences for the cynicism subscale. In the engagement evaluation, 29.4% presented high levels in the three subscales, 56.2% medium levels and 14.4% low levels. In the vigor subscale, there was a lower percentage of classification between low and very low in graduate students (p<!--> <!-->=<!--> <!-->0.01), along with similar values in high and very high. In the absorption subscale, there was a lower percentage of classification between high and very high in graduate students (p<!--> <!-->=<!--> <!-->0.04).</div></div><div><h3>Conclusions</h3><div>There was a low prevalence of burnout and a high prevalence of engagement in our population (total, undergraduate and graduate). However, a large proportion of students are at risk due to high levels of exhaustion. It is necessary to employ measures to reduce the levels of burnout and exhaustion, and to promote engagement, as well as to increase the investigation of the syndrome in university students.</div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 310-317"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47058714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Encefalitis autoinmune contra receptores NMDA con manifestaciones neuropsiquiátricas en el adulto. Reporte de caso y revisión de la literatura","authors":"","doi":"10.1016/j.rcp.2022.11.005","DOIUrl":"10.1016/j.rcp.2022.11.005","url":null,"abstract":"<div><h3>Background</h3><div>Anti-NMDA encephalitis is an autoimmune disease characterized by autoantibodies against NMDA receptors, confused with a primary psychiatric condition. There is a broad spectrum of neuropsychiatric symptoms, including refractory psychosis, impaired consciousness, and catatonia. Signs of autonomic instability, abnormal movements, seizures, and coma have also been associated. Patients may improve with immunotherapy and, if necessary, tumor removal.</div></div><div><h3>Objective</h3><div>To present the case of a 24-year-old woman with a diagnosis of anti-NMDA encephalitis without evidence of a tumor and with predominant psychiatric symptoms.</div></div><div><h3>Methods</h3><div>Case report and literature review.</div></div><div><h3>Results</h3><div>A brief review of the disorder is made with some data on its epidemiology, pathophysiology, therapeutic implications, and complex clinical expressions from the neuropsychiatric perspective, such as catatonic syndrome.</div></div><div><h3>Conclusion</h3><div>This case report exemplifies a clinical situation increasingly recognized in primary psychiatric practice and the general hospital; atypical psychiatric progression and catatonic symptoms indicated the possible presence of anti-NMDA encephalitis. Maintaining clinical suspicion of anti-NMDA encephalitis is considered essential, even when there is no evidence of tumor. Psychiatrists must be familiar with this entity to promote timely diagnosis and treatment.</div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 399-404"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43650673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Language Disorders Among Non-Disabled Children After Perinatal Asphyxia: A Cross Sectional Descriptive Study Using Neurolinguistic Approach","authors":"","doi":"10.1016/j.rcp.2023.01.003","DOIUrl":"10.1016/j.rcp.2023.01.003","url":null,"abstract":"<div><div><span><span><span>Neonatal hypoxic-ischemic encephalopathy after perinatal asphyxia causes neurolinguistic disturbances in children without disabilities. Poor academic performance appears as a long-term result. Language intervention is sought to reduce harmful effects on children. The aim of this study is showing the relationship between clinical conditions of hypoxic-ischemic-encephalopathy (HIE) and </span>language disorders in children without disabilities. This cross-sectional study with a neurolinguistic approach was carried out in patients with perinatal asphyxia during </span>childbirth<span>, at the ZH Sikder Women's Medical College Hospital, Bangladesh. Respondents between 4 and 12 years, 76% underwent cranial computed tomography (CT); 82% underwent magnetic resonance imaging (MRI); and 70% underwent electroencephalogram (EEG). Among them were found positive results for </span></span>neonatal hypoxia<span> ischemic encephalopathy (EHI). These results are related to the following language disorders: reception/perception disorder (64%), sociolinguistic disorders (84%); metalinguistic competence disorder (66%); 86% of children had poor peer relationships and 72% had reading and writing disorders. Concluding, school-age children after perinatal asphyxia who developed Hypoxic-Ischemic Encephalopathy (HIE) had language disorders and poor school performance. There are still challenges to be overcome, as this is the first neurolinguistic approach in Bangladesh. More large-scale studies are needed.</span></div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 238-245"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42485312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Issues Faced by General Practitioners in Managing Mental Health Disorders in Basic Health Units: a Cross-Sectional Study","authors":"","doi":"10.1016/j.rcp.2022.04.009","DOIUrl":"10.1016/j.rcp.2022.04.009","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the main issues faced by general practitioners when managing mental health disorders in the primary care setting and evaluate their interest in continued medical training on mental health.</div></div><div><h3>Methods</h3><div>We carried out a cross-sectional survey which included general practitioners (n=94) working in primary care in São Bernardo do Campo, SP, Brazil.</div></div><div><h3>Results</h3><div>Participants reported challenging issues to be as follows: psychiatric emergency (44.7%), alcohol and drug use disorders (35.1%), psychopharmacology (29.9%), and suicide risk assessment (27.6%). About a third of the sample reported a lack of knowledge on criteria regarding referral to psychiatric services. Almost the entire sample reported the need for better interaction between general practitioners and psychiatrists and interest in continued medical training.</div></div><div><h3>Conclusions</h3><div>Our findings support the evidence that a network between general practitioners and psychiatrists is needed as well as the improvement of continued medical training on mental health.</div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 278-283"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45750889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SPECT Cerebral en Pacientes con Síndrome de Cotard: a Propósito de dos Casos","authors":"","doi":"10.1016/j.rcp.2022.06.004","DOIUrl":"10.1016/j.rcp.2022.06.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Cotard's syndrome is a rare finding in psychiatry in which the denial of body parts, corporality and even existence, are the main features. In spite of the large number of reports and case series trying to elucidate the neurobiology of Cotard's syndrome, to date there are few studies with detailed descriptions of a possible neurobiological correlate.</div></div><div><h3>Methods</h3><div>Report of two cases and non-systematic review of the relevant literature.</div></div><div><h3>Case presentation</h3><div>The first case, a 24-year-old female patient with symptoms of Cotard's and Capgras syndrome, stated that she was dead, rotting inside her and that her family was supplanted by clones. The second case was a 50-year-old woman who mentioned being dead, not having arteries and veins. In functional neuroimaging studies, hypoperfusion was found in the frontal, parietal-temporal and basal ganglia regions.</div></div><div><h3>Literature review</h3><div>There is little literature regarding the relationship between Cotard's syndrome and functional neuroimaging studies. As reported in the literature, in our patients we found a decrease in cerebral perfusion at the frontal, parietal and temporal levels.</div></div><div><h3>Conclusions</h3><div>We found frontal, parieto-temporal and basal ganglia hypoperfusion in our patients with Cotard's syndrome.</div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 405-410"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48922511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validez y confiabilidad de la Wong-Law Emotional Intelligence Scale (WLEIS) en estudiantes cubanos de Estomatología en tiempos de COVID-19","authors":"","doi":"10.1016/j.rcp.2022.10.001","DOIUrl":"10.1016/j.rcp.2022.10.001","url":null,"abstract":"<div><h3>Introduction</h3><div>The pandemic produced by SARS-CoV-2 impacted on educative systems, which justifies the necessity of research about the emotional capacities of the university students to face the challenges that COVID-19 imposes.</div></div><div><h3>Objective</h3><div>To analyze the evidences of validity and reliability of the Wong-Law Emotional Intelligence Scale (WLEIS) in Cuban dental students.</div></div><div><h3>Materials and methods</h3><div>Cross-sectional study with instrumental design. The scale was administered through a virtual questionnaire and later distributed by means of social networks to 307 students (81 male and 226 female). A confirmatory factorial analysis was performed and the intern consistency and the relation between the scale and other variables were evaluated.</div></div><div><h3>Results</h3><div>Through the confirmatory factorial analysis, the model of four correlationated factors was evaluated and an adequate adjust was found, χ²(98)<!--> <!-->=<!--> <!-->303.1, <em>P</em> <!-->&lt;<!--> <!-->.001, CFI<!--> <!-->=<!--> <!-->0.948, TLI<!--> <!-->=<!--> <!-->0.937, RMSEA<!--> <!-->=<!--> <!-->0.083 and SRMR<!--> <!-->=<!--> <!-->0.064. The results of the Omega intern consistency are ω_SEA <!-->=<!--> <!-->0.84, ω_OEA <!-->=<!--> <!-->0.77, ω_UOE <!-->=<!--> <!-->0.83 and ω_UROE <!-->=<!--> <!-->0.91. With respect to the relation of WLEIS with other variables, we had correlations ranging from 0.22 and 0.51 with general well-being, and inverse correlations ranging from −1 and −0.29 of three of its dimensions with depression, showing evidences of convergent and discriminant validity.</div></div><div><h3>Conclusion</h3><div>The WLEIS in Cuban dental students in COVID-19 times resulted be valid and reliable.</div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 246-252"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40515053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relación entre el consumo de alcohol y el deterioro cognitivo en población adulta mayor de 60 años: una revisión sistemática","authors":"","doi":"10.1016/j.rcp.2022.08.004","DOIUrl":"10.1016/j.rcp.2022.08.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Alcohol is the most consumed substance in Western culture and its use is a causal factor in more than 200 diseases and disorders. Our objective was to determine the relationship between alcohol consumption and cognitive impairment in people aged ≥60, and identify which cognitive functions are most affected by prolonged alcohol consumption.</div></div><div><h3>Methods</h3><div>Search in MEDLINE, PsycInfo, Psicodoc, Cochrane and Web of Science databases. The search was limited to articles published from 2010 to 2020. A total of 8,716 articles were obtained. Those repeated and unrelated to the topic were eliminated, leaving a total of seven articles: five longitudinal studies, covering the relationship between alcohol and cognitive impairment; and two cross-sectional studies, which helped identify which cognitive functions are more affected. This systematic review was carried out in accordance with the criteria of the PRISMA statement.</div></div><div><h3>Results</h3><div>Most of the studies found conclude that no or excessive alcohol consumption is associated with a higher risk of cognitive impairment, compared to moderate consumption. In addition, excessive and prolonged alcohol consumption can evolve into secondary alcoholic dementia such as Marchiafava-Bignami disease, Wernicke-Korsakoff syndrome or pellagra. In people with alcohol use disorder, the cognitive functions that are most affected are executive functions, visuospatial skills, attention and memory.</div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 385-395"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48158969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estructura Interna y Validez del Reading the Mind in the Eyes Test Versión Niños en una Muestra Colombiana de Estudiantes de Secundaria","authors":"","doi":"10.1016/j.rcp.2022.07.002","DOIUrl":"10.1016/j.rcp.2022.07.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Social cognition is a broad set of processes related to interpersonal interaction, social adjustment, and a whole array of complex social behaviours. Disturbances in these processes are a key feature of many psychiatric disorders, therefore the adaptation and validation of assessment tools to measure social cognition performance are critical for correct diagnosis and treatment. One popular assessment tool is the Reading the Mind in the Eyes Test (RMET), which is used to measure individual ability regarding social cognition skills. Despite its remarkable popularity, to date there is no record about its psychometric features in Spanish-speaking children. Therefore, the aim of this research was to assess the internal consistency, convergent validity, and factorial structure of the RMET in children.</div></div><div><h3>Methods</h3><div>Our sample consisted of school students (n<!--> <!-->=<!--> <!-->509; 315 males, and 194 females) from sixth to ninth grade with ages ranging from 10 to 16 years old.</div></div><div><h3>Results</h3><div>The RMET has acceptable internal consistency, moderate convergent validity, and acceptable adjustment to a unidimensional factorial structure that could be improved by using a shortened version. No significant differences between sex and age groups were found, average performance scores of each test seem to be similar to those from akin cultural backgrounds (Spain or Argentina).</div></div><div><h3>Conclusions</h3><div>The RMET has acceptable reliability and validity and is therefore a suitable test for differentiating theory of mind skills in typically developing populations. Its psychometric properties should be investigated in clinical samples and other age groups.</div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 229-237"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46687944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalencia y Factores Asociados con las Quejas Cognitivas Subjetivas del Personal Sanitario Latinoamericano Durante la Pandemia de COVID-19","authors":"","doi":"10.1016/j.rcp.2022.07.008","DOIUrl":"10.1016/j.rcp.2022.07.008","url":null,"abstract":"<div><h3>Background and objectives</h3><div>An increase in emotional disturbances and complaints about cognitive performance has been observed in Latin American healthcare workers during the SARS-CoV-2 pandemic, which can affect attention capacity and increase the levels of stress and burnout of these professionals. The objective was to analyse subjective cognitive complaints (SCC) and associated factors in health personnel during the COVID-19 pandemic in five Latin American countries.</div></div><div><h3>Methods</h3><div>Multicentre cross-sectional study, which included 3,738 professionals from Colombia, Chile, Argentina, Ecuador, Bolivia, and Peru. The Generalized Anxiety Disorder Scale (GAD-7) and the Patient Health Questionnaire (PHQ-9) was used to assess depression, and the Mini-Z to assess Burnout. For the SCC, an item on cognitive concerns in attention and memory was used.</div></div><div><h3>Results</h3><div>The prevalence of cognitive complaints was 69.2%. The factors associated with a higher risk of SCC were the scores in the GAD-7, PHQ and Mini-Z, in addition to being part of the Ecuadorian health personnel.</div></div><div><h3>Conclusions</h3><div>There is a high prevalence of SCC in health personnel, which is modulated by emotional states and stress.</div></div>","PeriodicalId":52477,"journal":{"name":"Revista Colombiana de Psiquiatria","volume":"53 3","pages":"Pages 340-346"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33461529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}