European Journal of Translational and Clinical Medicine最新文献

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Characteristics of Patient at Rinology Divison Of Ear, Nose, And Throat Polyclinic in Prof. Dr. I.G.N.G. Ngoerah General Hospital Denpasar in 1 January 2020 – 31 December 2021 2020年1月1日至2021年12月31日登巴萨i . ng . g . Ngoerah总医院耳鼻喉综合诊所耳鼻喉科患者的特征
European Journal of Translational and Clinical Medicine Pub Date : 2023-09-18 DOI: 10.24018/clinicmed.2023.4.5.305
Ida Bagus Gede Hendra Kusuma, Sari Wulan Dwi Sutanegara
{"title":"Characteristics of Patient at Rinology Divison Of Ear, Nose, And Throat Polyclinic in Prof. Dr. I.G.N.G. Ngoerah General Hospital Denpasar in 1 January 2020 – 31 December 2021","authors":"Ida Bagus Gede Hendra Kusuma, Sari Wulan Dwi Sutanegara","doi":"10.24018/clinicmed.2023.4.5.305","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.5.305","url":null,"abstract":"Rhinology-related diseases are very common worldwide. Although not fatal, they may cause significant morbidity and reduce quality of life. We ai0med to describe the characteristics of patients in the rhinology division at the eye, nose and throat (ENT) Polyclinic, Prof. Hospital. Dr. I.G.N.G Ngoerah Denpasar in the period 1 January 2020 to 31 December 2021. It was a retrospective descriptive study which conducted in the rhinology division of the ENT Polyclinic, Prof. Hospital. Dr. I.G.N.G Ngoerah Denpasar from 1 January 2020 to 31 December 2021. A total of 752 patients underwent outpatient care during the period January 1, 2020, to December 31, 2021. Various rhinology cases found included inferior turbinate hypertrophy, nasal septum deviation, allergic rhinitis, bullous turbinate, nasal polyps, maxillary sinusitis, ethmoidal sinusitis, frontal sinusitis, sphenoidal sinusitis and pansinusitis. The most common diagnosis is inferior turbinate hypertrophy, and the least is frontal sinusitis. Inferior turbinate hypertrophy is commonly found in men and at the age of 41-50 years. The similar results also found in other cases, where it is more commonly found in men and at the age of 31-50 years. These results may contribute as a basic information to provide health care in general and to develop prevention strategy related to rhinology disease.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135153089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Observational Study of Risk Factors for SARS-CoV 2 Infection in Patients with Cancer 癌症患者SARS-CoV 2感染危险因素的观察性研究
European Journal of Translational and Clinical Medicine Pub Date : 2023-09-18 DOI: 10.24018/clinicmed.2023.4.5.254
Sonam Singla, Teena Wadhwa, Charu Yadav, Manish Singh, Smita Sarma, Nitin Sood, Ashok Vaid
{"title":"An Observational Study of Risk Factors for SARS-CoV 2 Infection in Patients with Cancer","authors":"Sonam Singla, Teena Wadhwa, Charu Yadav, Manish Singh, Smita Sarma, Nitin Sood, Ashok Vaid","doi":"10.24018/clinicmed.2023.4.5.254","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.5.254","url":null,"abstract":"Introduction: Cancer patients are regarded as a highly vulnerable population in Coronavirus Disease 2019 (COVID-19) pandemic due to their systemic immunosuppressive state. The aim of the study was to investigate the prevalence of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection in asymptomatic cancer patients attending the oncology clinic. Methods: We conducted a retrospective observational study from May- November 2020. The patients who tested positive for SARS-CoV-2 RT PCR were followed up to study the risk factors, clinical presentation, and outcome. The ethical approval from institutional review board was done. Chi-square test was used to compare qualitative variables and logistic regression model was used to estimate the odds ratio (OR) of having COVID-19 infection. Results: We included 334 cancer patients who were tested for COVID-19 infection. The prevalence of SARS-CoV-2 infection was 28.4%. COVID-19 infection was more common in solid organ malignancy than hematological cancer (29.2% vs. 26.1%). The risk of COVID-19 infection was associated with comorbidity (p = 0.002). Time since diagnosis of malignancy and the type of anticancer treatment received did not increase the risk of COVID-19 infection. However, patients receiving anticancer therapy in the last 4 weeks of testing positive for SARS-CoV-2 RT PCR had a higher risk for COVID-19 infection (p<0001). The oncological treatment was continued after resolution of symptoms and with negative RT-PCR. The multi variable regression model revealed that females, patients having both hypertension and diabetes mellitus and patients receiving chemotherapy within the last 4 weeks had higher odds of COVID-19 infection (p<0.05). Conclusion: We observed that active oncologic treatment does not represent a risk factor for SARS-CoV-2 infection in cancer patients. However delaying anticancer treatment to avoid SARS-CoV-2 transmission may lead to malignancy related complications. The approach of routine COVID 19 testing in cancer patients seems preferable in detecting asymptomatic virus carriers.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135153090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristic of Anatomical Variations in Paranasal Sinus CT-Scan of Chronic Rhinosinusitis Patients at the ENT Clinic Prof. Dr. I.G.N.G Ngoerah General Hospital Denpasar in 2021 耳鼻喉科门诊慢性鼻窦炎患者鼻窦ct扫描解剖变异特征
European Journal of Translational and Clinical Medicine Pub Date : 2023-09-14 DOI: 10.24018/clinicmed.2023.4.5.275
Sari Wulan Dwi Sutanegara, I Putu Yupindra Pradiptha
{"title":"Characteristic of Anatomical Variations in Paranasal Sinus CT-Scan of Chronic Rhinosinusitis Patients at the ENT Clinic Prof. Dr. I.G.N.G Ngoerah General Hospital Denpasar in 2021","authors":"Sari Wulan Dwi Sutanegara, I Putu Yupindra Pradiptha","doi":"10.24018/clinicmed.2023.4.5.275","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.5.275","url":null,"abstract":"Background: Anatomical variations and pathological processes in the nose and paranasal sinuses have been widely studied by experts. Many anatomical variations cause chronic sinusitis by causing obstruction of the osteomeatal complex (OMC) and influencing mucociliary transport patterns. Methods: This is a retrospective study based on radiology data of all rhinosinusitis cases that performed a computed tomography scan of the paranasal sinuses at Prof. Dr. I.G.N.G Ngoerah General Hospital Denpasar for one year (January 2021 to December 2021). The sample of this study was all rhinosinusitis patients undergoing surgery, both male and female, from January 1 to December 31, 2021. Results: Based on the results of the research data, the highest anatomical variation was concha hypertrophy in as many as 26 people (38.2%). Conclusion: The most common anatomic variation is concha hypertrophy. Preoperative CT scan examination is essential because it can be helpful as navigation for sinus surgeons. Early detection of anatomic variations is the key for surgical planning and the prevention of complications.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134910883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant Molluscum Contagiosum Opportunistic Infection in a HIV/AIDS Patient 1例HIV/AIDS患者巨大传染性软疣机会性感染
European Journal of Translational and Clinical Medicine Pub Date : 2023-09-08 DOI: 10.24018/clinicmed.2023.4.5.307
Suraj Arungiri Gosai, Sushmita Pandey, Abdul Khalid Qadree, Sandesh Dhakal, Anasonye Emmanuel Kelechi, Ajay Singh
{"title":"Giant Molluscum Contagiosum Opportunistic Infection in a HIV/AIDS Patient","authors":"Suraj Arungiri Gosai, Sushmita Pandey, Abdul Khalid Qadree, Sandesh Dhakal, Anasonye Emmanuel Kelechi, Ajay Singh","doi":"10.24018/clinicmed.2023.4.5.307","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.5.307","url":null,"abstract":"Atypical types of molluscum contagiosum (MC), which are present in immunocompromised patients and show substantial weakening of cellular immunity, can be difficult to diagnose. Low CD4 cell counts are associated with MC lesions, which are most frequently seen in HIV patients. We report MC lesions in the trunk and lower extremities in a 40-year-old HIV-positive female patient. A 75 cells/mm CD4 count was present in the patient. To rule out more dangerous disorders including dimorphic fungal infections, a skin biopsy was performed. The hypogastrum of the trunk and vulva were affected by the lesions which were painless, flesh-colored papules and nodules. Syphilis and hepatitis B virus testing came out negative, while serological tests for HIV-1 were positive. Intracytoplasmic molluscum bodies were detected in the skin biopsy. However, the opportunity for an early diagnosis in our case was lost.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136361747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperkalemia in Patients with Type 2 Diabetes Mellitus: Risk Factors and Clinical Outcomes 2型糖尿病患者的高钾血症:危险因素和临床结果
European Journal of Translational and Clinical Medicine Pub Date : 2023-08-31 DOI: 10.24018/clinicmed.2023.4.4.291
Rosnani Ab Rahman, Hafizuddin Awang, S. S. Syed Sulaiman
{"title":"Hyperkalemia in Patients with Type 2 Diabetes Mellitus: Risk Factors and Clinical Outcomes","authors":"Rosnani Ab Rahman, Hafizuddin Awang, S. S. Syed Sulaiman","doi":"10.24018/clinicmed.2023.4.4.291","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.4.291","url":null,"abstract":"Hyperkalemia is one of life-threatening electrolyte abnormalities. Diabetes mellitus (DM) is among the diseases in which patients can commonly develop hyperkalemia due to various factors. This study aimed to determine the occurrence of hyperkalemia and potential risk factors that contribute to development of hyperkalemia among type 2 diabetes mellitus (T2DM) patients. This is a single centered retrospective study in all deceased diabetic patients who were previously admitted to Sultan Ismail Petra Hospital, Kelantan state of Malaysia from January 2017 to December 2017 with or without hyperkalemia. A total of 132 patients were studied after screening for eligibility from medical records. Hyperkalemia was defined as potassium level ≥5.5 mEq/L. Univariate and multiple logistic regression analysis were used to identify potential risk factors associated with hyperkalemia. The occurrence of hyperkalemia among T2DM patients was 54.5%. In multivariable analysis, stage 4 CKD (eGFR: 15-29 ml/min/1.73m2) (AOR=0.154, 95%CI=0.003,0.763), use of ARB (AOR=26.269, 95%CI=1.25,548.50) and length of stay (AOR=1.007, 95%CI=1.001,1.013) were the significant risk factors for hyperkalemia. No significant difference between diabetes patients with hyperkalemia (DMHK) group with diabetes patients without hyperkalemia (DMWOHK) group in terms of clinical outcomes. Among diabetic patients with hyperkalemia, the mean time from development of hyperkalemia until death was 99.92±119.07 hours. In conclusion, this study shows that hyperkalemia is common among T2DM patient in our study setting. Although a number of factors may contribute to the high occurrence of hyperkalemia, the use of ARB, advanced CKD at stage 4 and length of stay are major determinants of hyperkalemia occurrence. Aggressive management of hyperkalemia may be beneficial as to prevent significant clinical outcomes requiring intensive care management and cardiac problem lead to death.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75776209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lost for Words – Bilateral Vocal Cord Paresis following Renal Dialysis of a Thyroidectomy Patient 失语-甲状腺切除术患者肾透析后双侧声带麻痹
European Journal of Translational and Clinical Medicine Pub Date : 2023-08-31 DOI: 10.24018/clinicmed.2023.4.4.304
Laurence Gluch, Deepali Poels
{"title":"Lost for Words – Bilateral Vocal Cord Paresis following Renal Dialysis of a Thyroidectomy Patient","authors":"Laurence Gluch, Deepali Poels","doi":"10.24018/clinicmed.2023.4.4.304","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.4.304","url":null,"abstract":"A patient underwent a total thyroidectomy for a small papillary thyroid cancer. Her vocal cord function was assessed as being normal post-operatively. A week later she underwent her first veno-venous renal dialysis for deteriorating renal function during the post-operative period. Within 48 hours she had developed bilateral vocal cord paresis, presumed to be on the basis of bilateral recurrent laryngeal nerve oedema precipitated by massive fluid shifts in the fresh surgical bed. Her voice recovered over the subsequent days as her fluid balance normalized.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135988534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation Between Type 2 Diabetes Mellitus with the Risk of Obstructive Sleep Apnea in Prof. Dr. I.G.N.G. Ngoerah Hospital Denpasar 2型糖尿病与阻塞性睡眠呼吸暂停风险的相关性研究
European Journal of Translational and Clinical Medicine Pub Date : 2023-07-14 DOI: 10.24018/clinicmed.2023.4.4.277
I. Putra, I. M. Wiranadha, Felicia Yumita Winata, Ida Kusuma
{"title":"Correlation Between Type 2 Diabetes Mellitus with the Risk of Obstructive Sleep Apnea in Prof. Dr. I.G.N.G. Ngoerah Hospital Denpasar","authors":"I. Putra, I. M. Wiranadha, Felicia Yumita Winata, Ida Kusuma","doi":"10.24018/clinicmed.2023.4.4.277","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.4.277","url":null,"abstract":"\u0000Background: Obstructive Sleep Apnea (OSA) is part of a complex sleep disordered breathing syndrome. OSA is defined by periods of respiratory events such as apneas, hypopneas, or respiratory effort related arousals during sleep, leading to hypoxia, waking during the night, excessive daytime sleepiness and hindering daily activities. In addition, OSA can also cause various systemic complications and even death. The occurrence of OSA is associated with the presence of metabolic disorders that cause type 2 diabetes mellitus (DM), with as many as 30% patients with OSA also have type 2 DM. The occurence of OSA are often underdiagnosed, especially in high-risk population. Therefore, the purpose of this study is to find out the relationship between type 2 DM with the risk of OSA.\u0000\u0000\u0000Methods: A cross sectional analytic study was conducted from June to August 2022 at Prof. Dr. I.G.N.G. Ngoerah Hospital Denpasar with a total of 80 respondents. The risk of OSA in the respondents was recorded using the Berlin questionnaire. \u0000\u0000\u0000Results: Of the 80 respondents, there were 33 people with a high risk of OSA and 47 people with a low risk of OSA. Respondents with a high risk of OSA were mostly male (78.6%), with the most ages between 51-60 years (53.6%), had type 2 DM (78.6%), and with nutritional status obese I (60.7%). There is a significant relationship between OSA and type 2 DM with a p-value of 0.019 (<0.05), a prevalence ratio of 3.3 with a 95% confidence interval (1.2-9.0), and a correlation coefficient of 0.254.\u0000\u0000\u0000Conclusion: There is a significant relationship between type 2 DM and OSA and is positively correlated. Type 2 DM is a risk factor of OSA, with 3.3 times the risk to develop a high risk OSA compared to patients without type 2 DM.\u0000","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87698246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Anaemia among Antenatal Clinic Attendees at A Tertiary Hospital in South West, Nigeria 在尼日利亚西南部的一家三级医院产前诊所的贫血患病率
European Journal of Translational and Clinical Medicine Pub Date : 2023-07-14 DOI: 10.24018/clinicmed.2023.4.4.274
T. Irinyenikan, Bamidele Jimoh Folarin, B. Alabi, A. Bade-Adefioye, Ismaila Sani
{"title":"Prevalence of Anaemia among Antenatal Clinic Attendees at A Tertiary Hospital in South West, Nigeria","authors":"T. Irinyenikan, Bamidele Jimoh Folarin, B. Alabi, A. Bade-Adefioye, Ismaila Sani","doi":"10.24018/clinicmed.2023.4.4.274","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.4.274","url":null,"abstract":"\u0000Introduction: Anaemia in pregnancy is a global public health problem causing both maternal and perinatal morbidities and mortalities. Prevalent rates vary from one geopolitical region to the other. Efforts have been made to reduce this condition during pregnancy through the use of haematinics and other interventions. However, despite all the efforts put in place, pregnant women still present with this condition. This study was carried out to find out its prevalence rate and the factors responsible for it.\u0000\u0000\u0000Materials and Methods: It was a cross-sectional institutional based study carried out at the antenatal clinic of the University of Medical Sciences Teaching Hospital Complex, Akure, Ondo State, South West, Nigeria. The study used a systematic sampling to recruit 400 antenatal clinic patients over a period of 16weeks starting from the 16th of August to 16th of December 2022.The women were interviewed with copies of a structured questionnaire administered by trained research doctors who also helped in the collection of the blood samples. About 3mls of venous blood was collected from the antecubital vein using plastic disposable syringes into sample bottles containing ethylene diamine-tetra acetic acid (EDTA) and the bottles labelled accordingly. Packed cell volume and red cell morphology were done for the women at the time of recruitment. Data obtained were analysed using the Statistical Package for Social Sciences (SPSS Version 22). Descriptive statistics were computed for all relevant variables, Chi Square test and Multivariate logistic regression were used to test for association and possible risk factors for anaemia. The level of significance was set at ???? < 0.05. \u0000\u0000\u0000Results: Most of the women were within 30years- 39years (51.2%, 205) with a mean age of 31.61years±5.37years. Most of them were married (97.3%, 389), were Christians (94.5%, 378), were Yorubas (82.8%, 331), were traders (40.3%, 161), had tertiary level of education (68.8%, 275) and lived in the urban areas of Ondo State (89.5%,358). Most had their first menses between the ages of 10 to 15 years (79.2%, 317) with a mean age of 14.24 ± 2.12 years. Majority had inter- pregnancy interval of ≤ 2 years (53.7%, 215). There was no history of bleeding in most of the women (91.5%, 366), many of them were in the third trimester of their pregnancy (64.1%, 257) with a mean gestational age of 28.83 ± 6.91 weeks. The prevalence of anaemia among the study participants was 40.0% (160/400) while 60% (240/400) were not anaemic. Among the participants who were anaemic, 77.5% (124/160) had mild anaemia, 22.5% (36/160) had moderate anaemia while none had severe anaemia. The only risk factors identified to be responsible for anaemia among the women were high parity and being in the third trimester of pregnancy.\u0000\u0000\u0000Conclusion: This study showed that the prevalence of anaemia is still high among our women mostly occurring among women of high parity and in the third trimester of pregnancy. Efforts must","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87826936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Spectrum of Intradialysis Complications in Renal Patients Accessing Care in A Tertiary Hospital in South East Nigeria 在尼日利亚东南部的一家三级医院获得护理的肾脏患者的分析并发症的频谱
European Journal of Translational and Clinical Medicine Pub Date : 2023-07-05 DOI: 10.24018/clinicmed.2023.4.4.264
S. Osineke, N. Jisieike-Onuigbo, I. Ulasi, Charles Odenigbo
{"title":"The Spectrum of Intradialysis Complications in Renal Patients Accessing Care in A Tertiary Hospital in South East Nigeria","authors":"S. Osineke, N. Jisieike-Onuigbo, I. Ulasi, Charles Odenigbo","doi":"10.24018/clinicmed.2023.4.4.264","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.4.264","url":null,"abstract":"\u0000Background: Haemodialysis (HD) is currently the most common mode of renal replacement therapy (RRT) in the Sub-Saharan Africa. It is however, fraught with many complications which sometimes cause morbidity and mortality outside the primary kidney problems. Hence, there must be concerted effort to identify them early. This would enable the clinician institute preventive measures or treat them efficiently when these adverse effects occur. \u0000\u0000\u0000Materials and Method: A prospective study was carried out among chronic kidney disease (CKD) and acute kidney injury (AKI) patients in failure assessing HD care at the Nnamdi Azikiwe University Teaching Hospital (NAUTH) Nnewi dialysis center. Subjects were one hundred and twenty six in number: 84 CKD and 42 AKI. Sixty five (65) were males while sixty one (61) were females.  A total of three hundred and sixty nine (369) HD sessions were done. Sociodemographic data and medical history were obtained from each subject and relevant physical examinations and laboratory investigations were carried out prior to and intra dialysis for each subject. Results were analyzed using Statistical Package for Social Sciences (SPSS) software version 17. \u0000\u0000\u0000Results: Intradialytic complications occurred in 86 out of 126 subjects. The commonest intradialytic complication was hypotension (20.6% for patient-based analysis and 21.1% for session-based analysis). This was followed by hypertension (19.8% for patient-based analysis and 16.5% for session-based analysis). Other complications noted were fever (9.95%), chest pain (9.95%), cramps (1.0%) and seizure (1.0%). \u0000\u0000\u0000Conclusion: In this study population, intradialysis hypotension was the most common complication followed by intradialysis hypertension. Patients on HD should be assessed and monitored actively to identify and possibly prevent or treat these complications when they occur.\u0000","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90567959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cryptococcal Meningitis in An Immunocompetent Patient 免疫功能正常患者的隐球菌性脑膜炎
European Journal of Translational and Clinical Medicine Pub Date : 2023-06-30 DOI: 10.24018/clinicmed.2023.4.3.273
Syed Hassan Tanvir Ramzi, S. Saleem, Ubaidullah Ansari, Fnu Namal, Y. Kiran
{"title":"Cryptococcal Meningitis in An Immunocompetent Patient","authors":"Syed Hassan Tanvir Ramzi, S. Saleem, Ubaidullah Ansari, Fnu Namal, Y. Kiran","doi":"10.24018/clinicmed.2023.4.3.273","DOIUrl":"https://doi.org/10.24018/clinicmed.2023.4.3.273","url":null,"abstract":"A fungal illness called cryptococcal meningitis is most often thought of as an opportunistic infection that affects immunocompromised people, typically those who have HIV infection. Numerous problems are linked to it, including widespread illness and neurologic ones such as intracranial hypertension, cerebral infarcts, vision loss, and other abnormalities. Here is a case 18-year-old male patient, who presented with persistent headache and fever. A lumbar puncture revealed a cryptococcal infection in him. His workup indicated no known underlying illness that may have compromised his immune system. CSF was then tested for cryptococcal species using an Indian ink preparation, and the results were positive. He was admitted to the hospital for initiation of antifungal therapy with amphotericin B along with serial serum creatinine and electrolytes levels and after the 5th day of getting amphotericin B, he had shown remarkable improvement in total symptomatology.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74224950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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