{"title":"1例HIV/AIDS患者巨大传染性软疣机会性感染","authors":"Suraj Arungiri Gosai, Sushmita Pandey, Abdul Khalid Qadree, Sandesh Dhakal, Anasonye Emmanuel Kelechi, Ajay Singh","doi":"10.24018/clinicmed.2023.4.5.307","DOIUrl":null,"url":null,"abstract":"Atypical types of molluscum contagiosum (MC), which are present in immunocompromised patients and show substantial weakening of cellular immunity, can be difficult to diagnose. Low CD4 cell counts are associated with MC lesions, which are most frequently seen in HIV patients. We report MC lesions in the trunk and lower extremities in a 40-year-old HIV-positive female patient. A 75 cells/mm CD4 count was present in the patient. To rule out more dangerous disorders including dimorphic fungal infections, a skin biopsy was performed. The hypogastrum of the trunk and vulva were affected by the lesions which were painless, flesh-colored papules and nodules. Syphilis and hepatitis B virus testing came out negative, while serological tests for HIV-1 were positive. Intracytoplasmic molluscum bodies were detected in the skin biopsy. However, the opportunity for an early diagnosis in our case was lost.","PeriodicalId":52409,"journal":{"name":"European Journal of Translational and Clinical Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Giant Molluscum Contagiosum Opportunistic Infection in a HIV/AIDS Patient\",\"authors\":\"Suraj Arungiri Gosai, Sushmita Pandey, Abdul Khalid Qadree, Sandesh Dhakal, Anasonye Emmanuel Kelechi, Ajay Singh\",\"doi\":\"10.24018/clinicmed.2023.4.5.307\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Atypical types of molluscum contagiosum (MC), which are present in immunocompromised patients and show substantial weakening of cellular immunity, can be difficult to diagnose. Low CD4 cell counts are associated with MC lesions, which are most frequently seen in HIV patients. We report MC lesions in the trunk and lower extremities in a 40-year-old HIV-positive female patient. A 75 cells/mm CD4 count was present in the patient. To rule out more dangerous disorders including dimorphic fungal infections, a skin biopsy was performed. The hypogastrum of the trunk and vulva were affected by the lesions which were painless, flesh-colored papules and nodules. Syphilis and hepatitis B virus testing came out negative, while serological tests for HIV-1 were positive. Intracytoplasmic molluscum bodies were detected in the skin biopsy. However, the opportunity for an early diagnosis in our case was lost.\",\"PeriodicalId\":52409,\"journal\":{\"name\":\"European Journal of Translational and Clinical Medicine\",\"volume\":\"21 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Translational and Clinical Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24018/clinicmed.2023.4.5.307\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Translational and Clinical Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24018/clinicmed.2023.4.5.307","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Giant Molluscum Contagiosum Opportunistic Infection in a HIV/AIDS Patient
Atypical types of molluscum contagiosum (MC), which are present in immunocompromised patients and show substantial weakening of cellular immunity, can be difficult to diagnose. Low CD4 cell counts are associated with MC lesions, which are most frequently seen in HIV patients. We report MC lesions in the trunk and lower extremities in a 40-year-old HIV-positive female patient. A 75 cells/mm CD4 count was present in the patient. To rule out more dangerous disorders including dimorphic fungal infections, a skin biopsy was performed. The hypogastrum of the trunk and vulva were affected by the lesions which were painless, flesh-colored papules and nodules. Syphilis and hepatitis B virus testing came out negative, while serological tests for HIV-1 were positive. Intracytoplasmic molluscum bodies were detected in the skin biopsy. However, the opportunity for an early diagnosis in our case was lost.