在尼日利亚西南部的一家三级医院产前诊所的贫血患病率

Q4 Medicine
T. Irinyenikan, Bamidele Jimoh Folarin, B. Alabi, A. Bade-Adefioye, Ismaila Sani
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引用次数: 0

摘要

妊娠期贫血是一个全球性的公共卫生问题,造成孕产妇和围产期发病率和死亡率。流行率因地缘政治区域而异。已作出努力,通过使用血液学和其他干预措施减少怀孕期间的这种情况。然而,尽管做出了所有的努力,孕妇仍然存在这种情况。本研究旨在了解其患病率及影响因素。材料和方法:这是一项基于机构的横断面研究,在尼日利亚西南部翁多州阿库尔医科大学教学医院综合体产前诊所进行。该研究采用系统抽样方法,从2022年8月16日到12月16日,在16周的时间里招募了400名产前门诊患者。这些妇女接受了一份结构化问卷的采访,问卷由训练有素的研究医生管理,他们也帮助收集血液样本。使用一次性塑料注射器从肘前静脉采集静脉血约3ml,装入含有乙二胺-四乙酸(EDTA)的样品瓶中,并贴上相应的标签。在招募时,对女性进行了填充细胞体积和红细胞形态的检测。使用社会科学统计软件包(SPSS Version 22)对获得的数据进行分析。对所有相关变量进行描述性统计,使用卡方检验和多变量logistic回归检验贫血的相关性和可能的危险因素。显著性水平设为????< 0.05。结果:30 ~ 39岁女性居多(51.2%,205例),平均年龄31.61±5.37岁。其中大多数人已婚(97.3%,389人),基督徒(94.5%,378人),约鲁巴人(82.8%,331人),商人(40.3%,161人),受过高等教育(68.8%,275人),居住在翁多州的城市地区(89.5%,358人)。初潮年龄以10 ~ 15岁居多(79.2%,317人),平均年龄14.24±2.12岁。大多数妊娠间隔≤2年(53.7%,215)。绝大多数(91.5%,366例)妇女无出血史,多发生在妊娠晚期(64.1%,257例),平均胎龄28.83±6.91周。研究参与者中贫血的患病率为40.0%(160/400),而60%(240/400)不贫血。在贫血的参与者中,77.5%(124/160)为轻度贫血,22.5%(36/160)为中度贫血,无重度贫血。唯一确定的导致妇女贫血的风险因素是胎次高和处于妊娠晚期。结论:本研究表明,我国妇女贫血的患病率仍然很高,主要发生在高胎次和妊娠晚期的妇女中。必须加强努力,通过使用可在孕前开始的血清学和关于需要在开始另一次怀孕之前从一次怀孕的影响中完全恢复的适当咨询来解决这种情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of Anaemia among Antenatal Clinic Attendees at A Tertiary Hospital in South West, Nigeria
Introduction: Anaemia in pregnancy is a global public health problem causing both maternal and perinatal morbidities and mortalities. Prevalent rates vary from one geopolitical region to the other. Efforts have been made to reduce this condition during pregnancy through the use of haematinics and other interventions. However, despite all the efforts put in place, pregnant women still present with this condition. This study was carried out to find out its prevalence rate and the factors responsible for it. Materials and Methods: It was a cross-sectional institutional based study carried out at the antenatal clinic of the University of Medical Sciences Teaching Hospital Complex, Akure, Ondo State, South West, Nigeria. The study used a systematic sampling to recruit 400 antenatal clinic patients over a period of 16weeks starting from the 16th of August to 16th of December 2022.The women were interviewed with copies of a structured questionnaire administered by trained research doctors who also helped in the collection of the blood samples. About 3mls of venous blood was collected from the antecubital vein using plastic disposable syringes into sample bottles containing ethylene diamine-tetra acetic acid (EDTA) and the bottles labelled accordingly. Packed cell volume and red cell morphology were done for the women at the time of recruitment. Data obtained were analysed using the Statistical Package for Social Sciences (SPSS Version 22). Descriptive statistics were computed for all relevant variables, Chi Square test and Multivariate logistic regression were used to test for association and possible risk factors for anaemia. The level of significance was set at ???? < 0.05. Results: Most of the women were within 30years- 39years (51.2%, 205) with a mean age of 31.61years±5.37years. Most of them were married (97.3%, 389), were Christians (94.5%, 378), were Yorubas (82.8%, 331), were traders (40.3%, 161), had tertiary level of education (68.8%, 275) and lived in the urban areas of Ondo State (89.5%,358). Most had their first menses between the ages of 10 to 15 years (79.2%, 317) with a mean age of 14.24 ± 2.12 years. Majority had inter- pregnancy interval of ≤ 2 years (53.7%, 215). There was no history of bleeding in most of the women (91.5%, 366), many of them were in the third trimester of their pregnancy (64.1%, 257) with a mean gestational age of 28.83 ± 6.91 weeks. The prevalence of anaemia among the study participants was 40.0% (160/400) while 60% (240/400) were not anaemic. Among the participants who were anaemic, 77.5% (124/160) had mild anaemia, 22.5% (36/160) had moderate anaemia while none had severe anaemia. The only risk factors identified to be responsible for anaemia among the women were high parity and being in the third trimester of pregnancy. Conclusion: This study showed that the prevalence of anaemia is still high among our women mostly occurring among women of high parity and in the third trimester of pregnancy. Efforts must be intensified to address this condition through the use of haematinics which can be started pre-conception and adequate counselling on the need to fully recover from the effects of one pregnancy before embarking on another.
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