Mary Blumenfeld, Casey Silvernale, Elena Stekolchik, Seema Rani
{"title":"Back to the Diving Board: A Rare Cause of Hemoptysis in a Healthy Female Athlete.","authors":"Mary Blumenfeld, Casey Silvernale, Elena Stekolchik, Seema Rani","doi":"10.1155/crpu/5227230","DOIUrl":"10.1155/crpu/5227230","url":null,"abstract":"<p><p>Lane-Hamilton syndrome is a rare association between idiopathic pulmonary hemosiderosis (IPH) and celiac disease that can present with isolated hemoptysis. We describe a case of a previously healthy 15-year-old female who presented with 1 month of intermittent hemoptysis, chest pain, and severe iron deficiency anemia. Physical examination was remarkable for mild conjunctival pallor and livedo reticularis. Extensive laboratory studies were obtained to rule out infectious, rheumatological, and oncological explanations of anemia. A chest radiograph showed an increased density in the left mid-lung and bilateral opacities, and computed tomography showed scattered multifocal ground glass opacities. Bronchoalveolar lavage revealed hemosiderin-laden macrophages consistent with the diagnosis of IPH. Additional workup for IPH revealed elevated celiac titers. Upper endoscopy confirmed the diagnosis of celiac disease, which led to a final diagnosis of Lane-Hamilton syndrome, a rare co-occurrence of IPH and celiac disease. The treatment plan included a course of systemic steroids and a gluten-free diet. Given this known association, workup for IPH should include testing for celiac disease since a gluten-free diet may prevent future occurrences of alveolar hemorrhage.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"5227230"},"PeriodicalIF":0.0,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12680453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145702738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ambra Migliarini, Alessandra Iacovelli, Flavio Marco Mirabelli, Rosaria Capone, Maria Luisa Nicolardi, Daniela Bosco, Flavia Adotti, Alessandra Oliva, Paolo Palange
{"title":"\"Spitting Stones\" and Broncholithiasis Caused by <i>Mycobacterium chimaera</i> in a Patient Affected by Bronchiectasis: A Rare Clinical Case.","authors":"Ambra Migliarini, Alessandra Iacovelli, Flavio Marco Mirabelli, Rosaria Capone, Maria Luisa Nicolardi, Daniela Bosco, Flavia Adotti, Alessandra Oliva, Paolo Palange","doi":"10.1155/crpu/8029074","DOIUrl":"10.1155/crpu/8029074","url":null,"abstract":"<p><p>We describe the case of a 62-year-old woman with underlying bronchiectasis who referred to our respiratory outpatient clinic for hemoptysis and lithoptysis, in addition to difficulty gaining weight over years. Chest CT scan revealed small pulmonary nodules, bronchiectasis with mucus plugs, and calcifications, both endobronchial and peribronchial. Bronchial lavage fluid was positive for <i>Mycobacterium (M.) chimaera</i>. A daily macrolide-based triple antibiotic therapy, including rifampicin, ethambutol, and azithromycin, was started. Broncholithiasis associated with pulmonary nontuberculous mycobacterial infection is a rare clinical condition. To the best of our knowledge, this is the first report of broncholithiasis due to <i>M. chimaera</i> infection.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"8029074"},"PeriodicalIF":0.0,"publicationDate":"2025-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145662667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Danger of Smoking on Home Oxygen: A Cautionary Case of Facial Flash Burn.","authors":"Angela Fadil, Samuel E Kennedy, Adam Austin","doi":"10.1155/crpu/6623790","DOIUrl":"10.1155/crpu/6623790","url":null,"abstract":"<p><p>For patients on oxygen therapy, close encounters with open flames carry a risk of morbid burns and airway injuries. Despite this, many patients prescribed long-term home oxygen therapy continue to smoke. This article describes one such case, demonstrating the consequences and emphasizing the importance of physician counseling and patient education.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"6623790"},"PeriodicalIF":0.0,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12662681/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145650019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary Tuberculosis Complicating Interstitial Lung Disease in Systemic Sclerosis: A Case Report from a High TB Burden Country.","authors":"Donny Ardika Novananda, Garinda Alma Duta, Resti Yudhawati Meliana, Aris Sudarwoko","doi":"10.1155/crpu/8525357","DOIUrl":"10.1155/crpu/8525357","url":null,"abstract":"<p><p>Systemic sclerosis (SSc) is a chronic connective tissue disease marked by immune system dysfunction, vascular damage, and progressing fibrosis involving the skin and various internal organs. Interstitial lung disease (ILD) represents one of the leading contributors to illness and death in patients with SSc. The management becomes more complex when complicated by opportunistic infections such as tuberculosis (TB), particularly in endemic regions. We present the case of a 45-year-old woman with complaints of generalized weakness for one-week, intermittent fever, nausea and vomiting, and a weight loss of 5 kg over the previous 2 months. Clinical examination showed skin thickening and sclerodactyly, which then diagnosed as SSc-associated ILD (SSc-ILD). High-resolution computed tomography (HRCT) revealed reticular changes, ground-glass opacities, and traction bronchiectasis, indicating a nonspecific interstitial pneumonia (NSIP) pattern. During the course of treatment, the patient developed a persistent productive cough, weight loss, and fever. Pulmonary TB was confirmed through acid-fast bacilli smear and GeneXpert testing. Early recognition of dual pathology and coordinated care among rheumatology, pulmonology, and infectious disease teams are crucial for optimizing outcomes. This case underlines the need for vigilance in managing immunosuppressed patients in TB-endemic settings and contributes to the literature on SSc-ILD complicated by active TB.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"8525357"},"PeriodicalIF":0.0,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12638133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145589924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
William McLean, Daisy Port, Daniel Sims, Olivia Curtis
{"title":"Group C Beta Haemolytic Streptococcus Causing Necrotising Pneumonia Complicated With a Pyopneumothorax.","authors":"William McLean, Daisy Port, Daniel Sims, Olivia Curtis","doi":"10.1155/crpu/8885401","DOIUrl":"10.1155/crpu/8885401","url":null,"abstract":"<p><strong>Introduction: </strong>Group C Beta Haemolytic Streptococcus (GCBHS) rarely causes invasive infection but is associated with high mortality. Pneumonia is common; however, severe necrotising pneumonia is very rare, and no previous cases complicated by pyopneumothorax have been described. Associations with male gender and animal exposure have been previously reported in the literature.</p><p><strong>Case: </strong>A 20-year-old male agriculture student with no past medical history presented with 6 days of productive cough and fever and 2 days of shortness of breath, chest pain, and confusion. He presented with clinical signs of sepsis, developed acute kidney injury (AKI), disseminated intravascular coagulation (DIC), and acute respiratory distress syndrome (ARDS) requiring intubation and ventilation. Initial computed tomography (CT) of the thorax showed right pyopneumothorax, left small pyopneumothorax, bilateral large pulmonary nodules of varying size, some cavitating with progression on serial imaging. Blood cultures grew GCBHS, later showing <i>Streptococcus dysgalactiae</i> subsp. <i>equisimilis</i> (<i>SDSE</i>). Bilateral chest drains were required, with eventual bilateral video-assisted thoracic surgery (VATS) with washout due to nonresolution. After a prolonged intensive care stay and a community course of antibiotics, his follow-up CT of the thorax is improving, and he is planning to return to his studies at agricultural college.</p><p><strong>Conclusion: </strong>Invasive infection with GCBHS is associated with higher mortality and prolonged hospital admission and may be zoonotic. Of the four reported cases of GCBHS necrotising pneumonia, all were young men with minimal or no past medical history. Half had documented exposure to unwell animals, and half required thoracoscopic intervention.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"8885401"},"PeriodicalIF":0.0,"publicationDate":"2025-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12595220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145483764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahshid Zohouri, Annam Zahid, Anthony Silvestre, Kayhon Rabbani, Karina Dargan, Justin Thomas
{"title":"A Rare Case of Pyopneumothorax Due to <i>Streptococcus intermedius</i> in a Previously Healthy Woman.","authors":"Mahshid Zohouri, Annam Zahid, Anthony Silvestre, Kayhon Rabbani, Karina Dargan, Justin Thomas","doi":"10.1155/crpu/1665286","DOIUrl":"10.1155/crpu/1665286","url":null,"abstract":"<p><p>Pyopneumothorax secondary to <i>Streptococcus intermedius</i> pneumonia contributed to the clinical deterioration and death of a previously healthy adult. This rare case emphasizes the potential for severe complications from common oral flora and the importance of prompt diagnosis and aggressive treatment of pyopneumothorax.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"1665286"},"PeriodicalIF":0.0,"publicationDate":"2025-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12575041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145433160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Theeb Osama Sulaiman, Abdullah Arshad, Fatima Al-Hattab, Mohammed Alkatib, Mona Al-Langawi, Mushtaq Ahmed
{"title":"Everolimus Induced Acute Fibrinous and Organizing Pneumonia (AFOP): A Rare Case Report.","authors":"Theeb Osama Sulaiman, Abdullah Arshad, Fatima Al-Hattab, Mohammed Alkatib, Mona Al-Langawi, Mushtaq Ahmed","doi":"10.1155/crpu/8402905","DOIUrl":"10.1155/crpu/8402905","url":null,"abstract":"<p><p>A variety of conditions have been associated with acute fibrinous and organizing pneumonia (AFOP), including autoimmune disorders, infectious agents, posttransplantation complications, and medications. Everolimus, an oral selective inhibitor of the mammalian target of rapamycin, is commonly used to manage metastatic malignancies such as breast cancer. Here, we describe a patient with a history of advanced breast cancer who developed AFOP secondary to everolimus, with the condition improving following discontinuation of the drug and initiation of steroid therapy.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"8402905"},"PeriodicalIF":0.0,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12539980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Usefulness of Telemonitoring in Respiratory Deterioration in a Patient Treated With Home High-Flow Nasal Therapy.","authors":"Jean-Michel Arnal, Thomas Obert, Aude Garnero","doi":"10.1155/crpu/9535168","DOIUrl":"10.1155/crpu/9535168","url":null,"abstract":"<p><p>A 63-year-old male with overlap syndrome had high-flow nasal cannula (HFNC) therapy added to his treatment in May 2023 after reporting reduced exercise tolerance due to dyspnea and recurrence of chronic bronchial congestion on existing therapy (noninvasive ventilation and appropriate drug treatment). HFNC therapy (Lumis HFT; ResMed) was started with prescribed usage of 2 h/day, a flow of 20 L/min, and a temperature of 37°C. Within 15 days, the patient noted improved clearance with thinner secretions, and then secretion volume decreased after 2 months. Six months after having HFNC connected to a telemonitoring platform (AirView), the homecare technician observed a sudden increase in HFNC usage (to > 4 h/day). After being contacted by the technician, the patient reported increased sputum production, low-grade fever, and exertional dyspnea. Evaluations found <i>Haemophilus influenzae</i>, and antibiotic therapy was started. The patient quickly improved and HFNC usage returned to the usual routine. Subsequently, the patient learned to adjust his HFNC usage based on the degree of bronchial congestion. This case report highlights the innovative value of telemonitoring as an early warning tool for exacerbations in patients receiving home high-flow nasal therapy, an aspect still scarcely documented in existing literature.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"9535168"},"PeriodicalIF":0.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12530940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Agata Anna Lewandowska, Dorota Waśniowska, Krzysztof Bronisz, Cezary Rybacki, Michał Graczyk, Helena Mirus-Arabik, Małgorzata Kołodziej, Aleksandra Gaczkowska, Ola Duszyńska
{"title":"Effects of Prolonged Antibiotic Therapy in Lung Abscesses-Analysis of Case Series.","authors":"Agata Anna Lewandowska, Dorota Waśniowska, Krzysztof Bronisz, Cezary Rybacki, Michał Graczyk, Helena Mirus-Arabik, Małgorzata Kołodziej, Aleksandra Gaczkowska, Ola Duszyńska","doi":"10.1155/crpu/5976252","DOIUrl":"10.1155/crpu/5976252","url":null,"abstract":"<p><p>The incidence and mortality rate of lung abscess cases have declined significantly following the widespread introduction of broad-spectrum antibiotic therapy. Administration of antibiotics is considered the main treatment option, replacing invasive management, which currently is reserved only for selected patients. Four cases of patients with large lung abscesses analyzed in the article demonstrate the effectiveness of prolonged antibiotic therapy in the form of clinical improvement and regression of lesions imaged with computed tomography (CT) scans, in the absence of surgical drainage. However, the lack of a comparator group undergoing surgical interventions limits the ability to generalize the findings. The article highlights multiple diagnostic and management challenges clinicians face when treating complicated lung abscesses; however, the presented evidence is limited by a small sample size and lack of controls. Although the incidence of lung abscesses has dropped, they are still frequently seen in pulmonology, surgery, pediatrics, and internal medicine departments. In the face of the worldwide antimicrobial resistance crisis, the choice of effective antibiotic therapy remains a challenge, and there is no consensus on the duration of the treatment, as well as specific timing for introducing surgical intervention. As there are no high-quality recommendations or international studies evaluating the epidemiology of lung abscesses in the 21st century, further research seems necessary to help clinicians make appropriate therapeutic decisions.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"5976252"},"PeriodicalIF":0.0,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12517991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145294212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bhavesh Mohan Lal, Michella K Whisman, Matthew A Steliga, Konstantinos Arnaoutakis
{"title":"Incidentally Detected Pulmonary Carcinoid Tumorlet With Coexisting Carcinoid Tumorlet in the Mediastinal Lymph Node in a Patient With Lung Cancer.","authors":"Bhavesh Mohan Lal, Michella K Whisman, Matthew A Steliga, Konstantinos Arnaoutakis","doi":"10.1155/crpu/9910270","DOIUrl":"10.1155/crpu/9910270","url":null,"abstract":"<p><p>Pulmonary carcinoid tumorlets are a cluster of neuroendocrine cells in the lung, which invade the basement membrane and are less than 5 mm in size. While similar to carcinoid tumors in all regards, they are differentiated from carcinoid tumors purely based on their size. They are generally considered benign, but lymph nodal involvement has been described in the past. It is unclear if lymph nodal involvement is due to metastasis to the lymph node or synchronous de novo proliferation of neuroendocrine cells in the lymph node as well. Here, we describe a patient with adenocarcinoma of the lung who was incidentally detected to have a pulmonary carcinoid tumorlet and a carcinoid tumorlet in the mediastinal lymph node.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2025 ","pages":"9910270"},"PeriodicalIF":0.0,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}