Mia Elhidsi, Dicky Soehardiman, Agung Wibawanto, Haris Maruli, Maryastuti, Prasenohadi, Elisna Syahruddin
{"title":"Bronchoscopy Laser and Silicone Y-Stents as Emergency Airway Management in Central Airway Stenosis Due to Secondary Thyroid Carcinoma: A Case Report.","authors":"Mia Elhidsi, Dicky Soehardiman, Agung Wibawanto, Haris Maruli, Maryastuti, Prasenohadi, Elisna Syahruddin","doi":"10.1155/2022/6338073","DOIUrl":"https://doi.org/10.1155/2022/6338073","url":null,"abstract":"<p><p>Total airway obstruction in thyroid cancer is rare and has high morbidity and mortality. Airway management in such cases is challenging, especially in cases in which thyroid masses cannot be totally resected. It is important to choose the appropriate airway treatment modality. Currently, therapeutic rigid bronchoscopy procedures and endoluminal lasers, as well as airway stent insertion, are a management modality of near-total malignant airway obstruction. We report a rigid bronchoscopy procedure combined with laser and Y-stent silicone insertion in thyroid cancer with extension infiltration, as well as compression in the trachea covering the subglottic tracheal area up to the main carina and tracheo-bronchomalacia, manifesting as acute respiratory failure.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":" ","pages":"6338073"},"PeriodicalIF":0.0,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9663233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40691932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silvia Martin Bote, Maria Angeles Herrera Morueco, Beatriz Arias Arcos, Javier García Lopez, Maria Belen Lopez-Muñiz Ballesteros
{"title":"Alveolar Proteinosis in COVID-19: Clinical Case.","authors":"Silvia Martin Bote, Maria Angeles Herrera Morueco, Beatriz Arias Arcos, Javier García Lopez, Maria Belen Lopez-Muñiz Ballesteros","doi":"10.1155/2022/1842566","DOIUrl":"https://doi.org/10.1155/2022/1842566","url":null,"abstract":"<p><p>Pulmonary alveolar proteinosis (PAP) is a rare, diffuse lung disease characterized by accumulation of lipoprotein in lung surfactant in the alveolar space and terminal bronchioles, leading to impaired gas exchange and arterial hypoxemia. We present the case of a 51-year-old woman who was admitted with a diagnosis of severe SARS-CoV-2 pneumonia. Her condition did not improve with corticosteroids. A chest CT scan revealed ground-glass opacities in all lung lobes, with septal thickening. A differential diagnosis was proposed with other diseases. Bronchoscopy revealed milky bronchoalveolar lavage fluid, and staining with periodic acid-Schiff was positive, thus indicating PAP. Therefore, the patient underwent whole lung lavage, which led to clinical, radiological, and functional improvement. In the context of the COVID-19 pandemic, differential diagnosis ensures that appropriate attention is given to less prevalent entities such as PAP.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":" ","pages":"1842566"},"PeriodicalIF":0.0,"publicationDate":"2022-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40659984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tofura Ullah, Sneh Chauhan, Joseph Friedman, Gideon Yoeli, Maximo Mora, Craig A Thurm
{"title":"Calcification in Thoracic Splenosis.","authors":"Tofura Ullah, Sneh Chauhan, Joseph Friedman, Gideon Yoeli, Maximo Mora, Craig A Thurm","doi":"10.1155/2022/9538355","DOIUrl":"https://doi.org/10.1155/2022/9538355","url":null,"abstract":"<p><p>Splenosis is a rare condition described as the implantation of ectopic splenic tissue, usually after a splenic rupture. Thoracic splenosis refers to acquired ectopic splenic tissue found within the thoracic cavity, often caused by thoracoabdominal trauma or surgery. Most cases are asymptomatic and many years may elapse before they are incidentally discovered on chest radiography or thoracic computed tomography. Splenosis is often misinterpreted as a malignancy on initial imaging. We wish to highlight a rare case of thoracic splenosis presenting with calcified and non-calcified nodules. Only two other cases of calcification have been reported in intrathoracic splenosis, neither of which provided CT images of this finding.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":" ","pages":"9538355"},"PeriodicalIF":0.0,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9578903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40660385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John Omotola Ogunkoya, Marion Itohan Ogunmola, Akinwale Folarin Ogunlade, Akindele Emmanuel Ladele
{"title":"COVID-19 Vaccination Associated Bilateral Pulmonary Embolism: Cause or Coincidence.","authors":"John Omotola Ogunkoya, Marion Itohan Ogunmola, Akinwale Folarin Ogunlade, Akindele Emmanuel Ladele","doi":"10.1155/2022/9596285","DOIUrl":"https://doi.org/10.1155/2022/9596285","url":null,"abstract":"<p><strong>Background: </strong>Acute pulmonary embolism (APE) is a common cause of morbidity and mortality all over the world. Sudden onset dyspnea and chest pain are characteristic. Prior to our index case, only two previous cases of bilateral pulmonary thromboembolism were reported in black Africans and the first to be associated with COVID-19 vaccination. These cases were seen and described in middle-aged men. <i>Case Summary</i>. A 59-year-old man presented with a 2 week history of sudden onset dyspnea and a week history of productive cough. No associated chest pain or hemoptysis. No preceding history suggestive of leg pain/swelling. The patient had the booster dose of moderna (mRNA) COVID-19 vaccine a month before the onset of symptoms. There was associated anorexia, generalized body pain, joint pain, and weakness. He had reduced oxygen saturation at presentation with tachycardia. CTPA showed nearly occlusive right and left pulmonary arteries.</p><p><strong>Conclusion: </strong>Bilateral acute pulmonary embolism is rare all over the world. Its association with COVID-19 vaccine administration is even rarer. However, the clinical presentations and investigation findings are similar to the descriptions available in the literature for unilateral APE.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":"2022 ","pages":"9596285"},"PeriodicalIF":0.0,"publicationDate":"2022-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33498268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Figueroa Rodriguez, Asfar Ghauri, Tony Abdo, Salim Daouk, Shideler Barbara, Houssein A Youness
{"title":"Navigational Bronchoscopy with Cryobiopsy for Diagnosis of ILD.","authors":"Fernando Figueroa Rodriguez, Asfar Ghauri, Tony Abdo, Salim Daouk, Shideler Barbara, Houssein A Youness","doi":"10.1155/2022/5128432","DOIUrl":"https://doi.org/10.1155/2022/5128432","url":null,"abstract":"<p><strong>Background: </strong>Interstitial lung diseases (ILDs) are a group of parenchymal pulmonary diseases in which pathologic diagnosis is essential. Although cryobiopsy has a high diagnostic yield, the complication rate remains high. <i>Case Presentation</i>. We report two cases of lung cryobiopsy guided by navigational bronchoscopy (LCB) for the diagnosis of ILD. In both cases, a CT chest angiogram (CTA) using a navigational protocol was performed. Targets were premarked and reached with the navigational system. Radial ultrasound (RU) was applied in combination with fluoroscopy guidance (FG) prior to sampling. Both patients achieved a final diagnosis; they were discharged home after procedure and no complications were noted. <i>Discussion</i>. By using a CTA with navigational guidance, we were able to perform cryobiopsy in areas with most disease activity and least vascularization.</p><p><strong>Conclusion: </strong>LCB used with navigational guidance for the diagnosis of ILD provides may be a safe and effective procedure that provides high diagnostic yield. Limitations include cost, availability, and expertise. Larger trials are needed to confirm the additional benefit.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":" ","pages":"5128432"},"PeriodicalIF":0.0,"publicationDate":"2022-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9509241/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40377412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicholas Graves, Julia Flint, Amol Sagdeo, Ayman Askari, Patrick Ball, Hana Morrissey
{"title":"Spontaneous Pneumothorax in a Patient with Systemic Lupus Erythematosus and Recent Infection with Coronavirus.","authors":"Nicholas Graves, Julia Flint, Amol Sagdeo, Ayman Askari, Patrick Ball, Hana Morrissey","doi":"10.1155/2022/9594063","DOIUrl":"https://doi.org/10.1155/2022/9594063","url":null,"abstract":"<p><p>A 50-year-old woman with a history of systemic lupus erythematosus and a recent infection with COVID-19 presented to the emergency department with acute shortness of breath twice in 10 days. She was diagnosed with myopericarditis attributed to COVID-19 infection (first admission), and chest X-ray revealed a small left-sided pneumothorax, pericardial effusion (second admission), with no mediastinal shift or other signs of tension. Computed tomography confirmed these results and revealed a few small cysts in the right lung. An echocardiogram demonstrated normal heart anatomy and filling dynamics. The patient was diagnosed with simple pneumothorax and ongoing myopericarditis managed with colchicine, ibuprofen, and low-dose prednisolone. The patient responded to treatment and was discharged. Pneumothorax association with COVID-19 is reported in a small number of publications, but the association is less clear with SLE. Our patient may have been predisposed to developing pneumothorax after COVID-19 infection due to her existing connective tissue disorder.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":" ","pages":"9594063"},"PeriodicalIF":0.0,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9424047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40335940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nicolas Barbarot, Emmanuelle Nourry, Nicolas Massart, François Legay, Matthieu Debarre, Pierre Fillatre, Eric Magalhaes, Arnaud Mari, Julien Wallois, Eric Briens, Stéphane Jouneau
{"title":"Treating Acute Severe Eosinophilic Asthma with IL-5 Inhibitors in ICU.","authors":"Nicolas Barbarot, Emmanuelle Nourry, Nicolas Massart, François Legay, Matthieu Debarre, Pierre Fillatre, Eric Magalhaes, Arnaud Mari, Julien Wallois, Eric Briens, Stéphane Jouneau","doi":"10.1155/2022/2180795","DOIUrl":"https://doi.org/10.1155/2022/2180795","url":null,"abstract":"<p><strong>Introduction: </strong>About 10% of the 300 million people worldwide who suffer from asthma have a severe disease that is uncontrolled despite treatment with inhaled corticosteroids and long-acting beta agonists. The eosinophilic inflammation pathway in the respiratory tract and blood is involved and interleukin-5 (IL-5) has recently been identified as a major promotor of this pathway. The anti-IL-5 antibodies reduce the incidence of exacerbation and allowed steroid sparing in severe asthma patients but only two case reports have been published on their use in critical care. <i>Case Presentation</i>. This report describes the extraordinary clinical improvement of a young patient with steroid-refractory eosinophilic acute severe asthma who required mechanical ventilation, VV-ECMO followed by treatment with mepolizumab. The salient point in this case is the use of an anti-IL-5 monoclonal antibody for a critically ill patient whose condition was deteriorating despite mechanical ventilation and VV-ECMO. The usual steroid treatment failed to control the increase in blood eosinophils or his bronchial inflammation and constriction.</p><p><strong>Conclusion: </strong>Anti-IL-5 antibodies are now a standard treatment for severe eosinophilic asthma that can also be useful in an emergency to treat steroid-refractory eosinophilic acute severe asthma.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":" ","pages":"2180795"},"PeriodicalIF":0.0,"publicationDate":"2022-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9420636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40335939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Azib Shahid, Harpreet Singh, Toni-Denise Espina, Mohammad Abdalla, Uzair Ghori, Bryan S Benn
{"title":"Noninvasive Management of Fractured Indwelling Tunneled Pleural Catheter Valve.","authors":"Azib Shahid, Harpreet Singh, Toni-Denise Espina, Mohammad Abdalla, Uzair Ghori, Bryan S Benn","doi":"10.1155/2022/2541285","DOIUrl":"https://doi.org/10.1155/2022/2541285","url":null,"abstract":"<p><p>Tunneled indwelling pleural catheters (IPCs) are frequently used to palliate symptomatic dyspnea due to recurrent pleural effusions. The drainage valve of IPCs is an important component of the catheter as fracture of the valve leads to malfunctioning of the IPCs. Replacement of the catheter includes risks such as pain, infection, pneumothorax, and procedure cost. We report two cases of malfunctioning tunneled IPC drainage valves repaired by our noninvasive method and discuss the need for a repair kit and a standardized approach to this repair in case of nonavailability of repair kits.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":" ","pages":"2541285"},"PeriodicalIF":0.0,"publicationDate":"2022-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40648627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sebastian Majewski, Maria Królikowska, Ulrich Costabel, Wojciech J Piotrowski, Marek Ochman
{"title":"Double Lung Transplantation for Idiopathic Pulmonary Fibrosis in a Patient with a History of Liver Transplantation and Prolonged Journey for Disease-Specific Antifibrotic Therapy.","authors":"Sebastian Majewski, Maria Królikowska, Ulrich Costabel, Wojciech J Piotrowski, Marek Ochman","doi":"10.1155/2022/4054339","DOIUrl":"https://doi.org/10.1155/2022/4054339","url":null,"abstract":"<p><p>Idiopathic pulmonary fibrosis (IPF) is characterized by uncontrolled progressive lung fibrosis with a median survival of 3 to 5 years. Although currently available pharmacotherapy cannot cure the disease, antifibrotics including pirfenidone and nintedanib were shown to slow disease progression and improve survival in IPF. Nevertheless, there is a knowledge gap on the safety of antifibrotics in patients after liver transplantation receiving concomitant immunosuppressive therapy. This case report of a 68-year-old male patient with IPF illustrates how a complex medical history has led to diagnostic and therapeutic challenges considerably affecting clinical decisions and impacting the patient's journey. The increasing severity of lung function impairment due to the progressive natural history of IPF ultimately led to severe respiratory failure. Double lung transplantation (LTx) was performed as the only therapeutic option in end-stage disease with the potential to improve quality of life and survival. To the best of our knowledge, this is the first case report describing the feasibility and safety of antifibrotic therapy with pirfenidone for IPF in a 68-year-old patient with a history of liver transplantation receiving concomitant immunosuppressive therapy with tacrolimus who underwent successful double lung transplantation when alternative medical interventions had been exhausted.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":" ","pages":"4054339"},"PeriodicalIF":0.0,"publicationDate":"2022-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9392625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40648628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giuliana Cerro Chiang, Christopher Lee, Alberto Marchevsky, Michael I Lewis
{"title":"Severe Nonspecific Interstitial Pneumonia (NSIP) in an Adolescent.","authors":"Giuliana Cerro Chiang, Christopher Lee, Alberto Marchevsky, Michael I Lewis","doi":"10.1155/2022/7757776","DOIUrl":"https://doi.org/10.1155/2022/7757776","url":null,"abstract":"<p><p>Childhood interstitial lung disease (chILD) is remarkably rare with a reported prevalence from 0.13 per 100,000 children under 17 years to 16.2 per 100,000 children under 15 years of age (Kornum et al., 2008). Here, we present a case of a 15-year-old with subacute hypoxemic respiratory failure, admitted to the critical care unit. Her imaging on admission showed bilateral interstitial infiltrates; her laboratory workup, including autoimmune serologies, was unrevealing. A bronchoscopy revealed the diagnosis of nonspecific interstitial pneumonia. She had a partial recovery after a course of steroids.</p>","PeriodicalId":52364,"journal":{"name":"Case Reports in Pulmonology","volume":" ","pages":"7757776"},"PeriodicalIF":0.0,"publicationDate":"2022-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9381257/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40708623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}