{"title":"Attachment patterns, self-compassion, and coping strategies in patients with chronic pain.","authors":"Iliana-Nefeli Nasika, Catherine Wiart, Anne-Sophie Bonvarlet, Jessica Guillaume, Amélie Yavchitz, Susana Tereno","doi":"10.1097/PR9.0000000000001087","DOIUrl":"10.1097/PR9.0000000000001087","url":null,"abstract":"<p><strong>Introduction: </strong>In the recent year's literature, attachment insecurity is described as a vulnerability factor among patients with chronic pain, associated with poor pain coping, anxiety, depression, catastrophizing, greater pain intensity, and disability. Self-compassion, on the other hand, is described as a protective factor, associated with lower levels of negative affect, catastrophizing, depression, and anxiety in patients with chronic pain.</p><p><strong>Methods: </strong>In this study, we aim to explore the association between attachment, self-compassion quality, and coping strategies, in patients with chronic pain. Thus, 134 eligible patients with chronic pain were recruited at the certified <i>Evaluation and Treatment Pain Center of the A. de Rothschild Foundation</i> in Paris. We used a sociodemographic questionnaire, the Relationship Scale Questionnaire (RSQ-RC), the Self-Compassion Scale, and the Brief COPE.</p><p><strong>Results: </strong>Results supported our principal hypothesis; securely attached participants reported a significantly higher global self-compassion score compared with insecurely attached ones. Secure attachment and higher self-compassion levels were positively correlated with functional coping strategies and negatively correlated with dysfunctional ones.</p><p><strong>Discussion: </strong>Attachment patterns may be the basis of someone's ability to be compassionate to himself and to cope adequately with a difficult situation, such as a chronic pain condition. An attachment-informed approach to pain management could offer a better understanding of the complexity of this clinical condition and potentially provide appropriate support for both patients and health professionals, aiming to improve the effectiveness of interventions.</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10789448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44937178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain ReportsPub Date : 2023-08-10eCollection Date: 2023-09-01DOI: 10.1097/PR9.0000000000001089
Giulia Di Stefano, Pietro Falco, Eleonora Galosi, Gianfranco De Stefano, Giuseppe Di Pietro, Caterina Leone, Daniel Litewczuk, Lorenzo Tramontana, Stefano Strano, Andrea Truini
{"title":"Pain associated with COVID-19 vaccination is unrelated to skin biopsy abnormalities.","authors":"Giulia Di Stefano, Pietro Falco, Eleonora Galosi, Gianfranco De Stefano, Giuseppe Di Pietro, Caterina Leone, Daniel Litewczuk, Lorenzo Tramontana, Stefano Strano, Andrea Truini","doi":"10.1097/PR9.0000000000001089","DOIUrl":"10.1097/PR9.0000000000001089","url":null,"abstract":"<p><strong>Introduction: </strong>Previous clinical observations raised the possibility that COVID-19 vaccination might trigger a small-fibre neuropathy.</p><p><strong>Objectives: </strong>In this uncontrolled observational study, we aimed to identify small fibre damage in patients complaining of generalized sensory symptoms and pain after COVID-19 vaccination.</p><p><strong>Methods: </strong>We collected clinical data, including a questionnaire for assessing autonomic symptoms (Composite Autonomic Symptom Score-31), and investigated quantitative sensory testing (QST) and skin biopsy in 15 prospectively enrolled patients with generalized sensory symptoms and pain after COVID-19 vaccination. Nine patients complaining of orthostatic intolerance also underwent cardiovascular autonomic tests.</p><p><strong>Results: </strong>We found that all patients experienced widespread pain, and most of them (11 of 15) had a fibromyalgia syndrome. All patients had normal skin biopsy findings, and in the 9 patients with orthostatic intolerance, cardiovascular autonomic tests showed normal findings. Nevertheless, 5 patients had cold and warm detection abnormalities at the QST investigation.</p><p><strong>Conclusions: </strong>In our study, most patients complaining of generalized sensory symptoms and pain after COVID-19 vaccination had clinical and diagnostic test findings compatible with a fibromyalgia syndrome. Although the abnormal QST findings we found in 5 patients might be compatible with a small-fibre neuropathy, they should be cautiously interpreted given the psychophysical characteristics of this diagnostic test. Further larger controlled studies are needed to define precisely the association between small fibre damage and COVID-19 vaccination.</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10789449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41378158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain ReportsPub Date : 2023-08-10eCollection Date: 2023-09-01DOI: 10.1097/PR9.0000000000001086
Harry L Hébert, Mathilde M V Pascal, Blair H Smith, David Wynick, David L H Bennett
{"title":"Big data, big consortia, and pain: UK Biobank, PAINSTORM, and DOLORisk.","authors":"Harry L Hébert, Mathilde M V Pascal, Blair H Smith, David Wynick, David L H Bennett","doi":"10.1097/PR9.0000000000001086","DOIUrl":"10.1097/PR9.0000000000001086","url":null,"abstract":"<p><p>Chronic pain (CP) is a common and often debilitating disorder that has major social and economic impacts. A subset of patients develop CP that significantly interferes with their activities of daily living and requires a high level of healthcare support. The challenge for treating physicians is in preventing the onset of refractory CP or effectively managing existing pain. To be able to do this, it is necessary to understand the risk factors, both genetic and environmental, for the onset of CP and response to treatment, as well as the pathogenesis of the disorder, which is highly heterogenous. However, studies of CP, particularly pain with neuropathic characteristics, have been hindered by a lack of consensus on phenotyping and data collection, making comparisons difficult. Furthermore, existing cohorts have suffered from small sample sizes meaning that analyses, especially genome-wide association studies, are insufficiently powered. The key to overcoming these issues is through the creation of large consortia such as DOLORisk and PAINSTORM and biorepositories, such as UK Biobank, where a common approach can be taken to CP phenotyping, which allows harmonisation across different cohorts and in turn increased study power. This review describes the approach that was used for studying neuropathic pain in DOLORisk and how this has informed current projects such as PAINSTORM, the rephenotyping of UK Biobank, and other endeavours. Moreover, an overview is provided of the outputs from these studies and the lessons learnt for future projects.</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10789453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46120523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain ReportsPub Date : 2023-08-07eCollection Date: 2023-09-01DOI: 10.1097/PR9.0000000000001084
Rachel Astles, Zihao Liu, Scott E Gillespie, Kristina W Lai, Alexander Maillis, Claudia R Morris, Peter A Lane, Lakshmanan Krishnamurti, Nitya Bakshi
{"title":"Sex and frequency of pain episodes are associated with acute pain trajectories in adolescents with sickle cell disease.","authors":"Rachel Astles, Zihao Liu, Scott E Gillespie, Kristina W Lai, Alexander Maillis, Claudia R Morris, Peter A Lane, Lakshmanan Krishnamurti, Nitya Bakshi","doi":"10.1097/PR9.0000000000001084","DOIUrl":"10.1097/PR9.0000000000001084","url":null,"abstract":"<p><strong>Introduction/objective: </strong>Acute pain episodes are a major cause of health care utilization (HCU) in sickle cell disease (SCD), and adolescence is associated with increased pain frequency. We sought to determine whether there were differences in acute pain trajectories by sex and frequency of pain episodes among adolescents with SCD who presented to the emergency department (ED).</p><p><strong>Methods: </strong>Retrospective review of electronic health records from a large, multicampus, pediatric SCD program.</p><p><strong>Results: </strong>Of the 113 adolescents included, the mean age was 16.6 (SD 0.9), 41.6% (n = 47) were female, 77.9% (n = 88) had HbSS or a similarly severe genotype, and 43.4% (n = 49) had ≥3 episodes of HCU for pain, which we defined as having history of high HCU for pain. Those with a history of high HCU for pain had higher mean pain intensity scores at presentation, were more likely to receive either intravenous or intranasal opioids, and were more likely to be hospitalized. In a model considering the 3-way interaction between sex, history of high HCU for pain, and follow-up time from the initial pain intensity score, adjusted for opioid per kilogram body weight, and prescription of hydroxyurea, adolescent female patients with high HCU for pain had the slowest decline in pain intensity during treatment for acute pain in the ED.</p><p><strong>Conclusion: </strong>Sex and history of high HCU for pain are associated with acute pain trajectories in adolescents with SCD presenting to the ED. These novel findings should be confirmed in future prospective studies.</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5c/a8/painreports-8-e1084.PMC10409410.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9973059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain ReportsPub Date : 2023-08-03eCollection Date: 2023-09-01DOI: 10.1097/PR9.0000000000001091
Judith Paredes Sanchez, Morgan Titmus, Hollie Lawson-Smith, Flavia Di Pietro
{"title":"Tactile acuity improves during acute experimental pain of the limb.","authors":"Judith Paredes Sanchez, Morgan Titmus, Hollie Lawson-Smith, Flavia Di Pietro","doi":"10.1097/PR9.0000000000001091","DOIUrl":"10.1097/PR9.0000000000001091","url":null,"abstract":"<p><strong>Introduction: </strong>Chronic pain is associated with poor tactile acuity, commonly measured with the 2-point discrimination (TPD) test. Although poor tactile acuity across chronic pain conditions is well established, less is known in acute pain.</p><p><strong>Objective: </strong>Recent conflicting findings in experimentally induced neck and back pain led us to conduct a TPD investigation in experimentally induced limb pain. We hypothesised altered TPD during experimental upper limb pain, but we did not speculate on the direction of the change.</p><p><strong>Methods: </strong>Thirty healthy subjects immersed their dominant hand in a circulating cold-water bath at 7°C (cold pressor test [CPT]). Two-point discrimination was measured at baseline (pre-CPT), during pain (during-CPT), and after withdrawal from the water (post-CPT) in 3 different sites: (1) the dominant forearm, (2) dominant arm and (3) contralateral forearm.</p><p><strong>Results: </strong>Repeated-measures analysis of variance revealed a significant main effect of time (F<sub>(2,56)</sub> = 4.45, <i>P</i> = 0.02, <math><mrow><msubsup><mi>η</mi><mi>p</mi><mn>2</mn></msubsup></mrow></math> = 0.14) on TPD; in all 3 sites, TPD values decreased (ie, tactile acuity improved) during pain. Interestingly, the contralateral forearm followed a similar pattern to the dominant (ie, painful) forearm, and furthermore was the only site that exhibited any correlation with pain, albeit in an intriguing direction (<i>r</i> = 0.57, <i>P</i> = 0.001), ie, the greater the pain the worse the tactile acuity.</p><p><strong>Conclusion: </strong>The improvements in tactile acuity during experimentally induced limb pain may reflect a protective response. The changes in the corresponding site in the contralateral limb may reflect a protective spinal cross talk. Such a response, together with the interesting relationship between tactile acuity and pain, warrant further inquiry.</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10789456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47519820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding the pain experience of lionfish envenomation.","authors":"Stephanie Mouchbahani-Constance, Manon Choinière, Reza Sharif-Naeini","doi":"10.1097/PR9.0000000000001090","DOIUrl":"10.1097/PR9.0000000000001090","url":null,"abstract":"<p><strong>Introduction: </strong>Stings from the lionfish (Pterois volitans) constitute one of the most painful wounds in the ocean. This species has invaded the Atlantic coast of the United States, Gulf of Mexico, Caribbean, and Mediterranean Sea. In addition to its ecological impact on local fish populations, stings from the lionfish pose a medical problem because of the debilitating nature of the pain they produce. However, there are no studies examining the human pain experience of lionfish stings.</p><p><strong>Objective: </strong>To characterize the various aspects of the pain experience following a lionfish sting.</p><p><strong>Methods: </strong>We developed a pain questionnaire that includes validated scales used with patients having acute or chronic pain to understand the pain variability, as well as the use of health care resources and treatments.</p><p><strong>Results: </strong>We provide the first study of the pain experience from lionfish stings. Here, we show that the pain is intense from the start and peaks approximately 1 hour later, resolving itself in 7 days for most victims. Furthermore, pain intensity can be influenced by several factors, including (1) age of the victim, where older victims experience significantly higher pain intensities, (2) the number of spines involved, (3) and whether infection occurred at the injury site. However, pain intensity was not different between male and female participants.</p><p><strong>Conclusion: </strong>These findings will inform the medical community on the pain experience and can be used by local authorities to better appreciate the impact of lionfish envenomations to develop programs aimed at curtailing the expansion of the lionfish.</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10789455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41570734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Decreased expression of hyaluronan synthase and loss of hyaluronan-rich cells in the anterior tibial fascia of the rat model of chemotherapy-induced peripheral neuropathy.","authors":"Ruilin Wang, Yoshikazu Matsuoka, Nobutaka Sue, Kosuke Nakatsuka, Chika Tsuboi, Hiroshi Morimatsu","doi":"10.1097/PR9.0000000000001088","DOIUrl":"https://doi.org/10.1097/PR9.0000000000001088","url":null,"abstract":"<p><strong>Introduction: </strong>Previous studies on chemotherapy-induced peripheral neuropathy (CIPN) have focused on neuronal damage. Although some studies have revealed that the fascia is an important sensory organ, currently, we do not know about chemotherapy drug-induced fascial dysfunction.</p><p><strong>Objectives: </strong>This study aimed to explore the fascia as a nonneural cause of mechanical hypersensitivity in CIPN by investigating the expression of hyaluronic acid synthase (HAS) and histology of the fascia in an animal model of CIPN.</p><p><strong>Methods: </strong>Rats were intraperitoneally administered with vincristine (VCR). Mechanical hypersensitivities of the hind paw and the anterior tibial muscle were assessed. The expression of HAS mRNA in the fascia of the anterior tibial muscles was quantitated using reverse transcription polymerase chain reaction. Immunohistochemistry was also performed for HAS2, hyaluronic acid-binding protein, and S100A4 in the fascia.</p><p><strong>Results: </strong>Vincristine administration significantly decreased mechanical withdrawal thresholds in the hind paw and the anterior tibial muscle after day 3. Quantitative polymerase chain reaction showed significant downregulation of HAS mRNAs in the fascia of VCR-treated rats. Immunohistochemical analysis showed that the number of cells with strong HAS2 immunoreactivity, classified as fasciacytes by morphology and colocalized marker S100A4, decreased significantly in the VCR group.</p><p><strong>Conclusion: </strong>Hyaluronic acid plays a critical role in somatic pain sensation. Damaged fascia could be a possible cause of musculoskeletal pain in patients with CIPN. This study suggests that fascia is a nonneural cause and novel therapeutic target for chemotherapy-induced \"peripheral neuropathy.\"</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10306437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9729613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain ReportsPub Date : 2023-07-01DOI: 10.1097/PR9.0000000000001078
Ritu Basnet, David Ruiz Mendez, Isaías Lugo-González, Edel O'Hagan, Mary O'Keeffe, Saurab Sharma, Joshua W Pate, David S Kennedy
{"title":"Online information on chronic pain in 3 countries: an assessment of readability, credibility, and accuracy.","authors":"Ritu Basnet, David Ruiz Mendez, Isaías Lugo-González, Edel O'Hagan, Mary O'Keeffe, Saurab Sharma, Joshua W Pate, David S Kennedy","doi":"10.1097/PR9.0000000000001078","DOIUrl":"https://doi.org/10.1097/PR9.0000000000001078","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the readability, credibility, and accuracy of online information on chronic pain in Australia, Mexico, and Nepal.</p><p><strong>Methods: </strong>We assessed Google-based websites and government health websites about chronic pain for readability (using the Flesch Kincaid Readability Ease tool), credibility (using the Journal of American Medical Association [JAMA] benchmark criteria and Health on the Net Code [HONcode]), and accuracy (using 3 core concepts of pain science education: (1) pain does not mean my body is damaged; (2) thoughts, emotions, and experiences affect pain; and (3) I can retrain my overactive pain system)<i>.</i></p><p><strong>Results: </strong>We assessed 71 Google-based websites and 15 government websites. There were no significant between-country differences in chronic pain information retrieved through Google for readability, credibility, or accuracy. Based on readability scores, the websites were \"fairly difficult to read,\" suitable for ages 15 to 17 years or grades 10 to 12 years. For credibility, less than 30% of all websites met the full JAMA criteria, and more than 60% were not HONcode certified. For accuracy, all 3 core concepts were present in less than 30% of websites. Moreover, we found that the Australian government websites have low readability but are credible, and the majority provided all 3 core concepts in pain science education. A single Mexican government website had low readability without any core concepts but was credible.</p><p><strong>Conclusion: </strong>The readability, credibility, and accuracy of online information on chronic pain should be improved internationally to support facilitating better management of chronic pain.</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/23/4e/painreports-8-e1078.PMC10278708.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9709219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain ReportsPub Date : 2023-07-01DOI: 10.1097/PR9.0000000000001081
Liam-Pierre Mathieu Tissot, David William Evans, Edward Kirby, Bernard Xian Wei Liew
{"title":"Tampa Scale of Kinesiophobia may underestimate task-specific fear of movement in people with and without low back pain.","authors":"Liam-Pierre Mathieu Tissot, David William Evans, Edward Kirby, Bernard Xian Wei Liew","doi":"10.1097/PR9.0000000000001081","DOIUrl":"https://doi.org/10.1097/PR9.0000000000001081","url":null,"abstract":"<p><strong>Introduction: </strong>The Tampa Scale of Kinesiophobia (TSK) is commonly used to assess fear of movement (FoM) in people with low back pain (LBP). However, the TSK does not provide a task-specific measure of FoM, whereas image-based or video-based methods may do so.</p><p><strong>Objectives: </strong>To compare the magnitude of FoM when assessed using 3 methods (TSK-11, image of lifting, video of lifting) in 3 groups of people: current LBP (LBP), recovered LBP (rLBP), and asymptomatic controls (control).</p><p><strong>Methods: </strong>Fifty-one participants completed the TSK-11 and rated their FoM when viewing images and videos depicting people lifting objects. Low back pain and rLBP participants also completed the Oswestry Disability Index (ODI). Linear mixed models were used to estimate the effects of methods (TSK-11, image, video) and group (control, LBP, rLBP). Linear regression models were used to assess associations between the methods on ODI after adjusting for group. Finally, a linear mixed model was used to understand the effects of method (image, video) and load (light, heavy) on fear.</p><p><strong>Results: </strong>In all groups, viewing images (<i>P</i> = 0.009) and videos (<i>P</i> = 0.038) elicited greater FoM than that captured by the TSK-11. Only the TSK-11 was significantly associated with the ODI (<i>P</i> < 0.001). Finally, there was a significant main effect of load on fear (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Fear of specific movements (eg, lifting) may be better measured using task-specific measures, such as images and videos, than by task-generic questionnaires, such as the TSK-11. Being more strongly associated with the ODI, the TSK-11 still plays an important role in understanding the impact of FoM on disability.</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10247215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9663317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain ReportsPub Date : 2023-07-01DOI: 10.1097/PR9.0000000000001085
Giulia Zerbini, Peter Justus Göller, Katharina Lembke, Miriam Kunz, Philipp Reicherts
{"title":"Relationship between chronotype and pain threshold in a sample of young healthy adults.","authors":"Giulia Zerbini, Peter Justus Göller, Katharina Lembke, Miriam Kunz, Philipp Reicherts","doi":"10.1097/PR9.0000000000001085","DOIUrl":"https://doi.org/10.1097/PR9.0000000000001085","url":null,"abstract":"<p><strong>Introduction: </strong>Chronotype indicates the biological preference for timing of activity and sleep. Being a late chronotype (ie, having a tendency for late sleep times) is associated with several mental and physical health problems. Previous studies found that late chronotypes are also more susceptible to chronic pain, but the relationship between chronotype and pain sensitivity remains unclear.</p><p><strong>Objectives: </strong>The aim of this study was to investigate the relationship between chronotype and heat pain threshold (as an indicator of pain sensitivity) in a sample of young healthy adults.</p><p><strong>Methods: </strong>We analyzed data from 316 young healthy adults participating in 4 different studies run at the Medical Faculty of the University of Augsburg. In all studies, chronotype and other sleep variables (eg, sleep duration) were assessed using the micro Munich ChronoType Questionnaire. Heat pain threshold was assessed with the method of adjustment.</p><p><strong>Results: </strong>Chronotype was not significantly associated with the heat pain threshold. Entering the other sleep variables in separate regression models did also not significantly explain variance in heat pain threshold.</p><p><strong>Conclusion: </strong>Our null findings are in contrast with previous notions that late chronotypes might be more sensitive to pain and more susceptible to chronic pain. Given the scarcity of the literature on this topic, more studies are needed to clarify the relationship between chronotype and pain sensitivity in different age populations, while also considering distinct pain modalities or other types of pain tests.</p>","PeriodicalId":52189,"journal":{"name":"Pain Reports","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/e5/painreports-8-e1085.PMC10287117.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9713373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}