The Korean journal of helicobacter and upper gastrointestinal research最新文献

{"title":"The Optimal Timing of Endoscopy in Nonvariceal Upper Gastrointestinal Bleeding-The Sooner, the Better?","authors":"Yonghoon Choi","doi":"10.7704/kjhugr.2024.0044","DOIUrl":"10.7704/kjhugr.2024.0044","url":null,"abstract":"","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"206-207"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Time of Endoscopy for Nonvariceal Upper Gastrointestinal Bleeding: An Observational Study.","authors":"Seong Woo Jeon, Joong Goo Kwon, Ju Yup Lee, Si Hyung Lee, Ho Jin Lee","doi":"10.7704/kjhugr.2024.0028","DOIUrl":"10.7704/kjhugr.2024.0028","url":null,"abstract":"<p><strong>Objectives: </strong>In cases of nonvariceal upper gastrointestinal bleeding (NVUGIB), endoscopic intervention within the first 24 hours is widely recommended. However, data on the efficacy of urgent endoscopy are limited. Here, we used the Glasgow-Blatchford score to assess bleeding outcomes based on time-to-endoscopy.</p><p><strong>Methods: </strong>Prospectively collected multicenter data, which included 1554 patients with NVUGIB, were retrospectively reviewed between February 2011 and December 2013. Based on time-to-endoscopy, patients were grouped into the early (<24 hours) versus the delayed (≥24 hours) group and the urgent (<6 hours) versus the nonurgent (≥6 hours) group. The rates of re-bleeding, mortality, secondary intervention, transfusion, and morbidity aggravation were analyzed.</p><p><strong>Results: </strong>The mean time-to-endoscopy and median Glasgow-Blatchford score were 33.0±75.5 hours and 12 (range: 1-23), respectively. Univariate analyses revealed that in the delayed endoscopy group, the transfusion and re-bleeding rates were higher (hazard ratio [HR]: 1.257, 95% confidence interval [CI]: 1.026-1.540) and lower (HR: 0.610, 95% CI: 0.413-0.901), respectively. Multivariate analysis revealed that delayed endoscopy was a significant factor for lower re-bleeding rate (HR: 0.576, 95% CI: 0.387- 0.859), which was prominent in the low-risk group (HR: 0.417, 95% CI: 0.225-0.774). Multivariate analysis showed that when compared with the low-risk group, in-hospital comorbidity aggravation was more common in high-risk patients who underwent non-urgent endoscopy (HR: 2.957, 95% CI: 1.045-6.454).</p><p><strong>Conclusions: </strong>In low-risk patients, delayed endoscopy is sufficient for NVUGIB management. In high-risk patients, urgent endoscopy reduced comorbidity aggravation during hospital care.</p>","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"267-275"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Vonoprazan Versus Intravenous Proton Pump Inhibitor for Prevention of High-Risk Peptic Ulcers Rebleeding After Endoscopic Hemostasis].","authors":"Jin Lee","doi":"10.7704/kjhugr.2024.0030","DOIUrl":"10.7704/kjhugr.2024.0030","url":null,"abstract":"","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"303-305"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Sex/Gender Differences in Esophageal Motility Disorders].","authors":"Ju Yup Lee","doi":"10.7704/kjhugr.2024.0037","DOIUrl":"10.7704/kjhugr.2024.0037","url":null,"abstract":"<p><p>Esophageal motility disorders are relatively rare and are attributed to an imbalance between the excitatory and inhibitory nerves that innervate the esophagus. These disorders include achalasia, distal esophageal spasms, and jackhammer esophagus. The prevalence of achalasia is equal in men and women; however, lower esophageal hypermotility disorders are slightly more common in women. Women with achalasia experience chest pain more frequently, whereas men tend to have high lower esophageal sphincter pressure. Additionally, women with achalasia respond better to pneumatic balloon dilatation than men. However, research on sex and gender differences in the outcomes of peroral endoscopic myotomy remains insufficient. Future studies should investigate the differences in outcomes, complications, and long-term effects to ensure optimal treatment in men and women with esophageal motility disorders. This research will be useful to develop sex-tailored treatments for esophageal motility disorders.</p>","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"298-300"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Kalimate-Associated Gastric Ulcer].","authors":"Tae Yeong Lee, Jong Kyu Park, Sang Jin Lee, Byeong-Joo Noh","doi":"10.7704/kjhugr.2024.0036","DOIUrl":"10.7704/kjhugr.2024.0036","url":null,"abstract":"<p><p>Kalimate (calcium polystyrene sulfonate) is a cation-exchange resin commonly used in clinical practice to treat hyperkalemia. However, Kalimate has been demonstrated to also cause serious gastrointestinal injuries, such as colonic necrosis, ulcerations, and perforations, in a subset of patients with chronic renal failure; these cases have been reported with and without the administration of hypertonic sorbitol. These lesions usually occur in the large or small intestine; lesions occurring in the stomach are rarely reported. We present the case of a 62-year-old woman with very large Kalimate-induced gastric ulcers that were mistaken for advanced gastric cancer in patients with chronic renal failure who had been taking Kalimate for the previous 3 months. The patient was successfully treated by discontinuing Kalimate and initiating a proton pump inhibitor.</p>","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"281-285"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Submucosal Dissection for Siewert II and III Early Gastric Cancer.","authors":"Raymond E Kim","doi":"10.7704/kjhugr.2024.0052","DOIUrl":"https://doi.org/10.7704/kjhugr.2024.0052","url":null,"abstract":"","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"201-202"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal Opening in Hypopharynx by Screening Upper Endoscopy.","authors":"Keun Sol Min, Jung-Hwan Oh","doi":"10.7704/kjhugr.2024.0042","DOIUrl":"10.7704/kjhugr.2024.0042","url":null,"abstract":"","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"301-302"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Atrophic Gastritis and Intestinal Metaplasia: A Latin American Perspective.","authors":"Arnoldo Riquelme, Felipe Silva, Diego Reyes, Gonzalo Latorre","doi":"10.7704/kjhugr.2024.0017","DOIUrl":"10.7704/kjhugr.2024.0017","url":null,"abstract":"<p><p>Gastric cancer (GC), a significant cause of mortality globally, is the leading cause of cancer-related deaths among Latin American men. GC is usually diagnosed at an advanced stage; therefore, therapeutic options are limited, and prognosis is poor. <i>Helicobacter pylori</i> infection remains the primary risk factor for GC; therefore, primary prevention directed toward diagnosis and treatment (\"test-and-treat\" strategy) is important. Western medicine guidelines recommend esophagogastroduodenoscopy (EGD) for at-risk individuals aged >40 years with regular surveillance in patients with gastric premalignant conditions (GPMC). However, limited availability of EGD in Latin America necessitates development of risk stratification tools to minimize the endoscopic burden. Results from the Chilean \"Endoscopic Cohort and Histological Operative Link on Gastric Assessment (OLGA) Staging\" (ECHOS study), propose endoscopic surveillance of advanced GPMC (OLGA/Operative Link for Gastric Intestinal Metaplasia [OLGIM] stages III-IV) with reliable risk stratification to facilitate early GC detection. Ensuring high-quality EGD and enhanced diagnostic yield of GPMC is essential. GPMC grading tools, such as the Kimura-Takemoto or Endoscopic Grading of Gastric Intestinal Metaplasia classification, should be incorporated into the regular risk assessment protocol. However, obtaining mapping gastric biopsies using standardized methods such as the updated Sydney System biopsy protocol, followed by grading of chronic atrophic gastritis with or without intestinal metaplasia using the OLGA and OLGIM staging systems are preferred for GC risk stratification. Recent GC prevention strategies recommended in Chile include a \"test-and-treat\" approach for <i>H. pylori</i> in individuals aged 35-44 years and combined <i>H. pylori</i>/pepsinogen I-II serology and EGD evaluation in patients aged >45 years to optimize the limited preventive resources available in the region.</p>","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"218-230"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes of Patients With Gastric Phytobezoars: Implication of Drinking Carbonated Beverages as a Treatment.","authors":"Jin Ook Jang, Cheol Woong Choi, Dae Gon Ryu, Su Bum Park, Su Jin Kim","doi":"10.7704/kjhugr.2024.0032","DOIUrl":"10.7704/kjhugr.2024.0032","url":null,"abstract":"<p><strong>Objectives: </strong>Although phytobezoars are the most common type of gastric bezoar, a standardized treatment method has not been adopted.</p><p><strong>Methods: </strong>In this study, we evaluated patient clinical features and treatment outcomes following the use of different treatment methods, with a focus on the efficacy of carbonated beverage consumption. A review of medical charts and endoscopic reports revealed 15 cases of gastric phytobezoars from September 2008 to May 2016. Patient medical records were retrospectively reviewed to assess patient clinical characteristics and treatment results.</p><p><strong>Results: </strong>The mean patient age was 71.3±11.1 years. The most common symptoms were epigastric pain (46.7%) and bloating (40.0%). A history of intra-abdominal surgery was found in 26.7% of the patients. The mean bezoar size was 47.3±14.5 mm. The final successful treatment methods were consumption of a carbonated beverage alone (n=7, 46.7%), endoscopic removal (n=5, 33.3%), and surgery (n=3, 20.0%). During the treatment course, few patients (3/15, 20.0%) experienced small bowel obstructions after the consumption of the carbonated beverage and endoscopic fragmentation; these obstructions required surgical interventions. There was no significant difference in the baseline characteristics between patients successfully or unsuccessfully treated with the carbonated beverage.</p><p><strong>Conclusions: </strong>Most patients presenting with gastric phytobezoars can be successfully treated by consuming carbonated beverages in conjunction with endoscopic therapy. However, small bowel obstructions may occur due to the migration of a fragmented bezoar, necessitating surgical intervention.</p>","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"259-266"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Coca-Cola Useful for Treating Gastric Bezoars?","authors":"Sang Hoon Lee, Sung Chul Park","doi":"10.7704/kjhugr.2024.0046","DOIUrl":"10.7704/kjhugr.2024.0046","url":null,"abstract":"","PeriodicalId":520887,"journal":{"name":"The Korean journal of helicobacter and upper gastrointestinal research","volume":"24 3","pages":"203-205"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967492/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144278186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}