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Correction to: "Limiting Premenstrual Endometrial Hypoxia Inducible Factor 2 Alpha May Fine-Tune Endometrial Function at Menstruation". 更正：“限制经前子宫内膜缺氧诱导因子2 α可微调月经期子宫内膜功能”。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf493
{"title":"Correction to: \"Limiting Premenstrual Endometrial Hypoxia Inducible Factor 2 Alpha May Fine-Tune Endometrial Function at Menstruation\".","authors":"","doi":"10.1210/clinem/dgaf493","DOIUrl":"10.1210/clinem/dgaf493","url":null,"abstract":"","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"e3931"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12527422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145007034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor from Su and Hasebe: "Genomic Correlations, Shared Loci, and Drug Targets Between Polycystic Ovary Syndrome and Asthma: Insights From Genome-Wide Association Analysis". Su和Hasebe致编辑的信：“多囊卵巢综合征和哮喘之间的基因组相关性、共享位点和药物靶点：来自全基因组关联分析的见解”。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf388
Chen-Yang Su, Masashi Hasebe
{"title":"Letter to the Editor from Su and Hasebe: \"Genomic Correlations, Shared Loci, and Drug Targets Between Polycystic Ovary Syndrome and Asthma: Insights From Genome-Wide Association Analysis\".","authors":"Chen-Yang Su, Masashi Hasebe","doi":"10.1210/clinem/dgaf388","DOIUrl":"10.1210/clinem/dgaf388","url":null,"abstract":"","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"e3916-e3917"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144593826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: "The Beneficial Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Anemia in Type 2 Diabetes-A Real-World Study". 更正：“钠-葡萄糖共转运蛋白2抑制剂对2型糖尿病贫血的有益作用-一项现实世界研究”。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf471
{"title":"Correction to: \"The Beneficial Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Anemia in Type 2 Diabetes-A Real-World Study\".","authors":"","doi":"10.1210/clinem/dgaf471","DOIUrl":"10.1210/clinem/dgaf471","url":null,"abstract":"","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"e3935"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144987113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to Letter to the Editor From Su and Hasebe: Genomic Correlations, Shared Loci, and Drug Targets Between Polycystic Ovary Syndrome and Asthma: Insights From Genome-Wide Association Analysis. 对Su和Hasebe致编辑的信的回复：多囊卵巢综合征和哮喘之间的基因组相关性、共享位点和药物靶点：来自全基因组关联分析的见解。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf389
Enting Ji, Min Hu, Hongxia Ma
{"title":"Response to Letter to the Editor From Su and Hasebe: Genomic Correlations, Shared Loci, and Drug Targets Between Polycystic Ovary Syndrome and Asthma: Insights From Genome-Wide Association Analysis.","authors":"Enting Ji, Min Hu, Hongxia Ma","doi":"10.1210/clinem/dgaf389","DOIUrl":"10.1210/clinem/dgaf389","url":null,"abstract":"","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"e3927-e3928"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144593827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Response to Letter to Editor From Yeap et al: "Endogenous Sex Steroid Hormones, Sex Hormone-Binding Globulin, and Risk of All-Cause and Cause-Specific Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies". 对Yeap等人致编辑的信的回复：“内源性性类固醇激素、性激素结合球蛋白与全因和病因特异性死亡风险：前瞻性队列研究的系统回顾和剂量反应荟萃分析”。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf415
Hamidreza Raeisi-Dehkordi, Mojgan Amiri, Sara Beigrezaei, Hugo G Quezada-Pinedo, Marinka Steur, Angeline Chatelan, Trudy Voortman, Oscar H Franco, Taulant Muka
{"title":"Response to Letter to Editor From Yeap et al: \"Endogenous Sex Steroid Hormones, Sex Hormone-Binding Globulin, and Risk of All-Cause and Cause-Specific Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies\".","authors":"Hamidreza Raeisi-Dehkordi, Mojgan Amiri, Sara Beigrezaei, Hugo G Quezada-Pinedo, Marinka Steur, Angeline Chatelan, Trudy Voortman, Oscar H Franco, Taulant Muka","doi":"10.1210/clinem/dgaf415","DOIUrl":"10.1210/clinem/dgaf415","url":null,"abstract":"","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"e3923-e3925"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor From Long: "Assessing the Cardiovascular Effects of Levothyroxine Use in an Aging United Kingdom Population (ACEL-UK): Cohort Study". Long给编辑的信：“评估在老龄化的英国人口中使用左甲状腺素的心血管影响（ACEL-UK）：队列研究”。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf419
Xianglin Long
{"title":"Letter to the Editor From Long: \"Assessing the Cardiovascular Effects of Levothyroxine Use in an Aging United Kingdom Population (ACEL-UK): Cohort Study\".","authors":"Xianglin Long","doi":"10.1210/clinem/dgaf419","DOIUrl":"10.1210/clinem/dgaf419","url":null,"abstract":"","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"e3909-e3910"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144677231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of Death and Adverse Effects in Patients on Liothyronine: A Multisource Systematic Review and Meta-analysis. 碘甲状腺原氨酸患者的死亡风险和不良反应：一项多源系统评价和荟萃分析。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf449
Suhani Bahl, Peter N Taylor, Lakdasa D Premawardhana, Mike Stedman, Adrian Heald, Colin M Dayan, Onyebuchi E Okosieme
{"title":"Risk of Death and Adverse Effects in Patients on Liothyronine: A Multisource Systematic Review and Meta-analysis.","authors":"Suhani Bahl, Peter N Taylor, Lakdasa D Premawardhana, Mike Stedman, Adrian Heald, Colin M Dayan, Onyebuchi E Okosieme","doi":"10.1210/clinem/dgaf449","DOIUrl":"10.1210/clinem/dgaf449","url":null,"abstract":"<p><strong>Context: </strong>Although some patients with hypothyroidism prefer combination therapy with liothyronine (LT3) and levothyroxine (LT4), the safety of LT3 remains unresolved.</p><p><strong>Objective: </strong>We undertook a multisource systematic review and meta-analysis of LT3 safety.</p><p><strong>Data sources: </strong>We searched PubMed for articles relating to death, adverse events (AEs), and cardiovascular outcomes in LT3 users. We also searched AEs data in the UK Yellow Card scheme and US Food and Drug Administration Adverse Reporting System (FAERS).</p><p><strong>Data extraction: </strong>Data was extracted independently by 2 reviewers. Out of 1814 articles identified, 52 studies were selected, comprising 21 randomized controlled trials (RCTs), 4 cohort studies, and 27 case reports. Meta-analyses were conducted for adverse outcomes in RCTs and cohort studies of combination vs monotherapy.</p><p><strong>Data synthesis: </strong>LT3-related AEs were only reported with unregulated LT3 use or pharmacy compounding errors. LT3 and LT4 showed similar adverse severity profiles in the Yellow Card scheme. Disproportionality analysis in the FAERS database showed no increased LT3 safety signals. A meta-analysis of RCTs (n = 2128) showed a similar AEs risk for combination vs monotherapy [relative risk (RR) 1.22, 95% confidence interval (CI) 0.66-2.25]. A cohort study meta-analysis (LT3 vs LT4-only users, n = 630 254) showed no increased risk of atrial fibrillation (RR 1.10, 95% CI 0.74-1.63), heart failure (RR 1.54, 95% CI 0.95-2.47), or strokes (RR 0.86, 95% CI 0.11-6.75), but reduced mortality risk was observed for LT3 (RR 0.70, 95% CI 0.62-0.78).</p><p><strong>Conclusion: </strong>Our findings are reassuring that regulated LT3 use is not associated with the risk of death or serious AEs. More studies are needed to supplement existing data.</p>","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"3278-3288"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12527464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144839948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to Editor From Yeap et al: "Endogenous Sex Steroid Hormones, Sex Hormone-binding Globulin, and Risk of All-cause and Cause-specific Mortality: A Systematic Review and Dose-response Meta-analysis of Prospective Cohort Studies". Yeap等人致编辑的信：“内源性性类固醇激素、性激素结合球蛋白与全因和病因特异性死亡风险：前瞻性队列研究的系统回顾和剂量反应荟萃分析”。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf414
Bu B Yeap, Ross J Marriott, Leen Antonio, Leon Flicker, Gary A Wittert, Frederick C W Wu, Kevin Murray
{"title":"Letter to Editor From Yeap et al: \"Endogenous Sex Steroid Hormones, Sex Hormone-binding Globulin, and Risk of All-cause and Cause-specific Mortality: A Systematic Review and Dose-response Meta-analysis of Prospective Cohort Studies\".","authors":"Bu B Yeap, Ross J Marriott, Leen Antonio, Leon Flicker, Gary A Wittert, Frederick C W Wu, Kevin Murray","doi":"10.1210/clinem/dgaf414","DOIUrl":"10.1210/clinem/dgaf414","url":null,"abstract":"","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"e3912-e3913"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Approach to the Patient With a Difference of Sexual Development. 方法与患者性发育的差异有关。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf386
Hannes Syryn, Elfride De Baere, Martine Cools
{"title":"Approach to the Patient With a Difference of Sexual Development.","authors":"Hannes Syryn, Elfride De Baere, Martine Cools","doi":"10.1210/clinem/dgaf386","DOIUrl":"10.1210/clinem/dgaf386","url":null,"abstract":"<p><p>Available prenatal and postnatal tests for obtaining a molecular genetic diagnosis for differences of sexual development (DSD) have largely expanded over the last decade. More importantly, the medical management of these conditions has taken a different approach, with greater emphasis on patient autonomy, holistic care, and psychosocial support. These changes are illustrated through the discussion of 2 cases with a common form of DSD. While the principles and recommendations for the diagnosis and medical management of DSD are universal in nature, they need to be translated into clinical care pathways that align with the specific sociocultural background of patients and their caregivers to ensure the best possible outcome. Considering the inherent global differences in the organization and accessibility of health care and available resources, this requires an individualized approach based on shared decision-making and clinical guidelines that are in line with local facilities and societal context.</p>","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"3264-3277"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor From Hasebe and Su: "Adrenalectomy Reduces the Risk of Vertebral Fractures in Patients With Mild Autonomous Cortisol Secretion". Hasebe和Su致编辑的信：“肾上腺切除术降低轻度自主皮质醇分泌患者椎体骨折的风险”。
IF 5.1
The Journal of clinical endocrinology and metabolism Pub Date : 2025-10-16 DOI: 10.1210/clinem/dgaf384
Masashi Hasebe, Chen-Yang Su
{"title":"Letter to the Editor From Hasebe and Su: \"Adrenalectomy Reduces the Risk of Vertebral Fractures in Patients With Mild Autonomous Cortisol Secretion\".","authors":"Masashi Hasebe, Chen-Yang Su","doi":"10.1210/clinem/dgaf384","DOIUrl":"10.1210/clinem/dgaf384","url":null,"abstract":"","PeriodicalId":520805,"journal":{"name":"The Journal of clinical endocrinology and metabolism","volume":" ","pages":"e3918-e3919"},"PeriodicalIF":5.1,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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