The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease最新文献_第5页

Double trouble: enhancing integrated services for TB and diabetes. 双重难题：加强结核病和糖尿病的综合服务。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-06-01 DOI: 10.5588/ijtld.25.0526

K Jayendran, M N Williams, N Shongwe, F Xaba, N Dlamini, A A Howard, N Ginindza, D Vambe, J E Mantell, Y Hirsch-Moverman

{"title":"Double trouble: enhancing integrated services for TB and diabetes.","authors":"K Jayendran, M N Williams, N Shongwe, F Xaba, N Dlamini, A A Howard, N Ginindza, D Vambe, J E Mantell, Y Hirsch-Moverman","doi":"10.5588/ijtld.25.0526","DOIUrl":"10.5588/ijtld.25.0526","url":null,"abstract":"<sec><title>BACKGROUND</title>TB remains a global health challenge, particularly in low- and middle-income countries. Diabetes mellitus (DM) further increases the risk of developing active TB. The WHO recommends integrating DM screening and care into TB clinics to improve patient outcomes.</sec><sec><title>METHODS</title>A TB-DM educational pamphlet for patients was developed in collaboration with key stakeholders. Seventeen health care providers (HCPs) from urban and rural TB facilities in Manzini, Eswatini, participated in in-depth interviews to share their perspectives on integrating TB-DM services and the pamphlet's potential role in patient care.</sec><sec><title>RESULTS</title>The majority of HCPs felt confident diagnosing DM in people with TB. To improve TB-DM services, they recommended increasing the availability of patient education materials, standardising diagnostic tools, providing additional training and supervision from nurse mentors, and improving access to pharmacological information. Most agreed that the pamphlet could enhance patient and family education while motivating adherence to lifestyle recommendations. Suggestions for improving the pamphlet included simplifying and contextualising the dietary and exercise information to ensure that it is relevant and understandable for a Swazi lay audience.</sec><sec><title>CONCLUSION</title>Strengthening diagnostic procedures, expanding training, improving patient education, and increasing nurse mentor support are essential for better integrated TB-DM services and improved health outcomes in Eswatini.</sec>.","PeriodicalId":520801,"journal":{"name":"The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease","volume":"30 6","pages":"237-243"},"PeriodicalIF":3.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148146132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of non-tuberculous mycobacteria: results from the national network of public laboratories in Peru. 非结核分枝杆菌分析：来自秘鲁国家公共实验室网络的结果。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-06-01 DOI: 10.5588/ijtld.25.0718

Z M Puyen, E Pacheco, J Terrazas, L Solari

{"title":"Analysis of non-tuberculous mycobacteria: results from the national network of public laboratories in Peru.","authors":"Z M Puyen, E Pacheco, J Terrazas, L Solari","doi":"10.5588/ijtld.25.0718","DOIUrl":"10.5588/ijtld.25.0718","url":null,"abstract":"<sec><title>BACKGROUND</title>In Peru, there are relatively few reports on non-TB mycobacteria (NTM). We therefore aimed to synthesise the results of public laboratories' registers of NTM.</sec><sec><title>METHODS</title>We reviewed the information of the National Reference Laboratory for Mycobacteria of the Instituto Nacional de Salud (INS), Peru, from 2020 to 2024. Samples of isolates with suspicion of NTM were sent to the INS, where species identification was performed.</sec><sec><title>RESULTS</title>2,520 specimens were included for analysis. The number of NTM detected rose from 345 in 2020 to 584 in 2024. We identified 19 species of NTM, the most frequent being Mycobacterium fortuitum (n = 57; 22.6%), M. intracellulare (n = 434; 17.2%), and M. abscessus complex (n = 217; 8.6%). There were 647 (25.7%) specimens that were not identified. Cases of NTM predominated in the (north) coast and in the forest regions of the country.</sec><sec><title>DISCUSSION</title>The epidemiology of NTM in Peru is complex, and the distribution of the different species shows a wide variation between regions. The increasing trends in NTM demand urgent improvements to diagnostic capacity in the regions and raised awareness of this health problem. The high proportion of unidentified species (25.7%) also requires further investigation.</sec>.","PeriodicalId":520801,"journal":{"name":"The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease","volume":"30 6","pages":"277-284"},"PeriodicalIF":3.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148146098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methodology and scope of peer-reviewed evaluations of TB programmes in high-incidence settings: a scoping review. 高发病率环境中结核病规划同行评议评估的方法和范围：范围审查

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-06-01 DOI: 10.5588/ijtld.25.0569

G Nijman, B W Lestari, C Adolph, R M Baltussen, A D Harries, B Alisjahbana, R van Crevel, P C Hill

{"title":"Methodology and scope of peer-reviewed evaluations of TB programmes in high-incidence settings: a scoping review.","authors":"G Nijman, B W Lestari, C Adolph, R M Baltussen, A D Harries, B Alisjahbana, R van Crevel, P C Hill","doi":"10.5588/ijtld.25.0569","DOIUrl":"10.5588/ijtld.25.0569","url":null,"abstract":"<sec><title>BACKGROUND</title>TB disease control programmes routinely report on basic performance indicators, such as case detection or treatment success. Structures, processes, and quality of care are also important. We assessed published TB programme evaluations with respect to these basic and wider system factors.</sec><sec><title>METHODS</title>We conducted a scoping review of English peer-reviewed literature. We included articles if they presented TB programme evaluations in high-TB-incidence settings. We extracted data across domains and indicators to describe scope and methodology across the TB programme wider system.</sec><sec><title>RESULTS</title>The search yielded 885 articles, of which 57 were included. The majority (73.7%) did not use a systematic approach to indicator selection and 71.9% had unclear indicator definitions. Reports tended to be narrow in scope and focused on quality of care (89.5%), infrastructure and supplies (70.2%), human resources (70.2%), and outcomes/cascade of care (59.6%). Access to care (42.1%), engagement with community and patients (31.6%), knowledge and information (29.8%), leadership and governance (26.3%), and finances (26.3%) were infrequently evaluated.</sec><sec><title>CONCLUSION</title>TB programme evaluations vary in methodology and reporting, and are limited in scope. A more strategic and systematic combined approach to operational research, external evaluation, and internal diagnostic control systems would be beneficial for TB programmes.</sec>.","PeriodicalId":520801,"journal":{"name":"The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease","volume":"30 6","pages":"255-269"},"PeriodicalIF":3.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148146138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of BPaL to treat RR/MDR-TB, pre-XDR-TB, and extensive disease: real-world outcomes from a cohort in Germany. 使用BPaL治疗耐药/耐多药结核病、前广泛耐药结核病和广泛疾病：来自德国队列的真实结果

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-06-01 DOI: 10.5588/ijtld.25.0650

J Trauth, J Kohlhaas, V Dreyer, M Kuhns, I Friesen, S Herold

引用次数: 0

Pretomanid dosing and pharmacokinetics in patients with TB in a high-resource setting. 在高资源环境下结核病患者的Pretomanid剂量和药代动力学。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-06-01 DOI: 10.5588/ijtld.25.0620

N F Maranchick, C A Peloquin, C A Haley

引用次数: 0

Prevalence of and readiness to reduce alcohol use and smoking among adults with TB and HIV in Ukraine. 乌克兰感染结核病和艾滋病毒的成年人中减少饮酒和吸烟的流行程度和意愿。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-06-01 DOI: 10.5588/ijtld.25.0701

K Calver, Y Sereda, O Makarenko, N Gnatienko, K Hook, C W Kahler, T Kiriazova, K Lunze

引用次数: 0

Antigen-based skin tests in community-wide active case finding for TB. 基于抗原的皮肤试验在社区结核病活跃病例发现中的应用

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-06-01 DOI: 10.5588/ijtld.25.0571

M Ahson, S Kern-Allely, N Mintz, B Gleason, D Fred, R Brostrom

{"title":"Antigen-based skin tests in community-wide active case finding for TB.","authors":"M Ahson, S Kern-Allely, N Mintz, B Gleason, D Fred, R Brostrom","doi":"10.5588/ijtld.25.0571","DOIUrl":"10.5588/ijtld.25.0571","url":null,"abstract":"<sec><title>BACKGROUND</title>In 2022, Mycobacterium tuberculosis antigen-based skin tests (TBSTs) were added to global recommendations for diagnosing TB infection (TBI). TBSTs have higher specificity than tuberculin skin tests (TSTs), particularly in Bacillus Calmette-Guérin (BCG)-vaccinated populations. We report results from community-wide TB active case finding (ACF) using TBSTs in remote, high-incidence communities.</sec><sec><title>METHODS</title>From May to June 2024, TBSTs were implemented in community-wide ACF for TB in the Mortlock and Northwest Islands of the Federated States of Micronesia. Home interviews and TBSTs were conducted, with follow-up at mobile clinics. If indicated, chest radiography and sputum collection were performed to evaluate for TB disease. Treatment for TBI or TB disease was initiated upon diagnosis. Programmatic data were analysed to compare TBST positivity rates with a matched TST-tested population from 2023.</sec><sec><title>RESULTS</title>1,354 participants completed ACF screening; 186 (13.7%) had a positive TBST result. Of these, 163 were diagnosed with TBI and 23 with TB disease. No adverse events were reported. TBST positivity was 0.65 times that of a propensity-matched TST-tested population.</sec><sec><title>CONCLUSION</title>TBST was both feasible and safe for community-wide ACF in remote settings. Lower TBST positivity may correlate with improved test specificity, indicative of fewer false positives in this BCG-vaccinated population.</sec>.","PeriodicalId":520801,"journal":{"name":"The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease","volume":"30 6","pages":"270-276"},"PeriodicalIF":3.1,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13264380/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148146114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-TB mycobacterial diseases: negligence or helplessness? 非结核分枝杆菌疾病：疏忽还是无助？

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-04-27 DOI: 10.5588/ijtld.26.0030

S Singh

引用次数: 0

Retrospective analysis of TB screening in vulnerable populations in low-burden settings. 低负担地区易感人群结核病筛查的回顾性分析。

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-04-27 DOI: 10.5588/ijtld.25.0392

M A Jiménez-Fuentes, M Luiza de Souza-Galvão, E Lara López, C Broto Cortés, J E Ospina, A Denial, R Prieto Garcia, E Sulleiro, M T Tórtola, X Casas, I Molina-Pinargote, Y S Gonzalez Díaz, J P Millet

{"title":"Retrospective analysis of TB screening in vulnerable populations in low-burden settings.","authors":"M A Jiménez-Fuentes, M Luiza de Souza-Galvão, E Lara López, C Broto Cortés, J E Ospina, A Denial, R Prieto Garcia, E Sulleiro, M T Tórtola, X Casas, I Molina-Pinargote, Y S Gonzalez Díaz, J P Millet","doi":"10.5588/ijtld.25.0392","DOIUrl":"10.5588/ijtld.25.0392","url":null,"abstract":"<sec><title>BACKGROUND</title>In high-income countries, TB has a major impact on vulnerable populations. Active case-finding (ACF) strategies target these populations, allowing the identification of TB in asymptomatic individuals and improving the local epidemiological situation.</sec><sec><title>OBJECTIVES</title>To evaluate the impact of ACF and define the factors associated with a higher probability of presenting TB in vulnerable populations, we performed an observational, descriptive, and retrospective study. We analysed the results of ACF studies performed in vulnerable populations (social service users, drug users, and recent migrants from high-TB areas) in Barcelona between 2018 and 2024.</sec><sec><title>RESULTS</title>10,149 records of vulnerable individuals were studied. Seventy-three people were diagnosed and treated for TB (0.72%). There was microbiological confirmation in 47 (64.4%). Resistance to isoniazid was detected in two cases (2.7%) and multi-drug resistance in six (8.2%). Treatment was completed in 64 (87.7%). Risk factors associated with TB were: age less than 30 years (prevalence ratio [PR] = 4.1; 95% confidence interval [CI]: 1.6-10.5), homelessness (PR = 4.0; 95% CI: 2.6-9.2), and being a migrant (PR = 6.2; 95% CI: 2.6-9.2), with residence less than 5 years (PR = 4.4; 95% CI: 2.1-9.2).</sec><sec><title>CONCLUSION</title>ACF targeting vulnerable populations allows the early detection of TB. Priority should be given to the study of groups at higher risk of developing TB, such as homeless people and recent migrants.</sec>.","PeriodicalId":520801,"journal":{"name":"The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease","volume":"30 5","pages":"198-202"},"PeriodicalIF":3.1,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of an integrated TB-diabetes mellitus health care model. 结核-糖尿病综合保健模式的影响

IF 3.1

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease Pub Date : 2026-04-27 DOI: 10.5588/ijtld.25.0607

M A Habib, S S Efa, K Afrin, N Islam, M D Hossain

引用次数: 0