The International journal of risk & safety in medicine最新文献

Noradrenaline reuptake inhibitors (NRIs) for attention deficit hyperactivity disorder (ADHD) in adults. 去甲肾上腺素再摄取抑制剂（NRIs）治疗成人注意缺陷多动障碍（ADHD）。

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-09-17 DOI: 10.1177/09246479261461033

Dilyara Nurkhametova, Ekaterina V Yudina, Yinghui Wei, Tatyana Abakumova, Liliya Eugenevna Ziganshina

{"title":"Noradrenaline reuptake inhibitors (NRIs) for attention deficit hyperactivity disorder (ADHD) in adults.","authors":"Dilyara Nurkhametova, Ekaterina V Yudina, Yinghui Wei, Tatyana Abakumova, Liliya Eugenevna Ziganshina","doi":"10.1177/09246479261461033","DOIUrl":"https://doi.org/10.1177/09246479261461033","url":null,"abstract":"RationaleAttention deficit hyperactivity disorder (ADHD) in adults is controversial. Noradrenaline reuptake inhibitors (NRIs) are used for treatment. It's unclear how helpful/harmful they are.ObjectivesThis review brings together available evidence to evaluate the benefits and harms of NRIs in adults with ADHD.MethodsWe searched for all randomised controlled trials that compared NRIs to placebo/no treatment in bibliographic databases (April 2025) and synthesised their results. We assessed the certainty of evidence applying GRADE.ResultsWe included 21 trials, 5124 participants from Europe, Americas and Asia. NRIs may have little to no effect on people's ability to function in daily life, or on improving ADHD symptoms and quality of life. NRIs increased treatment discontinuation (RR 1.16, 95% CI [1.03, 1.30]) and non-serious adverse events (AEs) (RR 1.27, 95% CI [1.09, 1.49]), both with very low certainty. Atomoxetine increased serious AEs (RR 2.31, 95% CI [1.79, 2.97]; moderate certainty).ConclusionsThere is probably more harm (compared to placebo) with atomoxetine use in adults, with over two-fold increase in the number of people with serious (life-threatening) adverse events, a higher proportion of people with any adverse event amongst patients taking atomoxetine and higher withdrawal rates of people treated with atomoxetine or reboxetine.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261461033"},"PeriodicalIF":0.8,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacovigilance awareness and adverse events reaction reporting practices among pharmacy students in Iraq: A cross-sectional study. 伊拉克药学学生的药物警戒意识和不良事件反应报告实践：一项横断面研究。

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-09-13 DOI: 10.1177/09246479261489069

Samer Shukur Mohammed

{"title":"Pharmacovigilance awareness and adverse events reaction reporting practices among pharmacy students in Iraq: A cross-sectional study.","authors":"Samer Shukur Mohammed","doi":"10.1177/09246479261489069","DOIUrl":"https://doi.org/10.1177/09246479261489069","url":null,"abstract":"IntroductionPharmacovigilance (PV) plays an important role in ensuring the safety of medicines through detecting, assessing, and preventing adverse drug reactions (ADR) associated with medicine use. Despite the importance of ADR, several studies showed limited awareness and underreporting of ADRs among healthcare students, particularly in developing countries.AimThis study aimed to assess the knowledge, attitudes and practices (KAP) of Iraqi pharmacy students regarding PV and ADR reporting, Identify the barriers influencing their reporting and examine differences in KAP by academic level (final year vs 1-4 year).MethodsA cross-sectional survey was conducted among 412 pharmacy students from various private and government universities and colleges in Iraq. A structured, validated questionnaire was employed to assess the participant's demographics, KAP and barriers to ADR reporting. Data were analysed using SPSS, with chi-square tests used to determine associations; p < 0.05 was considered to indicate significance.ResultsMost participants (60.4%) had never heard of PV, and 55.8% rated their knowledge as poor. Only 29.8% had reported an ADR, and 70.1% had never done so; insufficient knowledge of reporting procedures was the most frequently cited barrier (56.3%). Attitudes were more positive, with 74% acknowledging the importance of ADR reporting. Gender was not significantly associated with KAP (p > 0.05). Final year students showed significant improvement in their knowledge and attitudes (p < 0.05).ConclusionPharmacy students in Iraq demonstrated limited knowledge and practice regarding PV. However, they exhibited positive attitudes toward it. These findings underscore the urgent need to integrate PV education into pharmacy curricula, strengthen practical training and foster collaboration with regulatory authorities to enhance ADR reporting before graduation.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261489069"},"PeriodicalIF":0.8,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148956828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deprescribing of beta-blocker and RAAS inhibitors in heart failure patients: A narrative review. 心衰患者β受体阻滞剂和RAAS抑制剂的处方解除：叙述性回顾。

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-09-04 DOI: 10.1177/09246479261481001

Vina Septiani, Lia Amalia, M Rizki Akbar, Kusnandar Anggadiredja

{"title":"Deprescribing of beta-blocker and RAAS inhibitors in heart failure patients: A narrative review.","authors":"Vina Septiani, Lia Amalia, M Rizki Akbar, Kusnandar Anggadiredja","doi":"10.1177/09246479261481001","DOIUrl":"https://doi.org/10.1177/09246479261481001","url":null,"abstract":"Background: There are four pillars in the treatment of heart failure. During treatment, heart failure patients generally require therapy adjustment, which was deprescribing practice. Aim: This review aimed to study outcomes from deprescribing of beta blockers and renin-angiotensin aldosterone system inhibitors (RAASIs) in heart failure patients. Methods: A narrative review was carried out. The search was conducted in May 2025, using Pubmed, Cochrane Library, and Scopus. Eligible studies included randomized controlled trials (RCTs), observational studies, and retrospective studies. Interventions included deprescribing of guideline-directed medical therapy (GDMT), or beta blocker, or RAASIs. Only articles published in English between 2015 and 2025 were included in the search. Results: The search and screening resulted in seven evaluable articles. Conclusion: The current review shows that negative outcomes from deprescribing of beta blockers or RAASIs were dominant. Other measures were, therefore, needed to be taken into consideration for a better benefit/risk balance.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261481001"},"PeriodicalIF":0.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148893329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wearable health trackers: A potential candidate for behavioural addiction? 可穿戴健康追踪器：行为成瘾的潜在候选者？

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-08-24 DOI: 10.1177/09246479261481003

Raja Babu Ramawat, Omar Afroz, Siddharth Sarkar

{"title":"Wearable health trackers: A potential candidate for behavioural addiction?","authors":"Raja Babu Ramawat, Omar Afroz, Siddharth Sarkar","doi":"10.1177/09246479261481003","DOIUrl":"https://doi.org/10.1177/09246479261481003","url":null,"abstract":"Wearable health trackers are a type of health and fitness self-service technology that is becoming increasingly popular. Effective monitoring of health parameters offered through these devices helps in planning physical activity and weight reduction, with studies reporting their use in rehabilitation for chronic medical illnesses. However, the potential risks and harms associated with these devices remain underexplored. Apart from physical risks, such as increased risk of accidents, psychological issues related to the use of these devices include stress, guilt, low mood, and health anxiety. When criteria for behavioural addiction are applied to the use of these devices, the criteria of clinical relevance and phenomenology of use appear to be partly met, while there is a lack of data on theoretical understanding or taxonomic plausibility. We suggest that these devices be considered as a potential candidate for research on behavioural addiction. At the same time, we argue against overmedicalizing behaviours without evidence and call for a balanced approach in research to determine both the benefits and potential harms associated with wearable health trackers.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261481003"},"PeriodicalIF":0.8,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148815481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stevens-Johnson Syndrome identified at the University Hospital Center of Libreville, Gabon: Four case reports. 加蓬利伯维尔大学医院中心发现的史蒂文斯-约翰逊综合征：4例报告。

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-08-21 DOI: 10.1177/09246479261479445

Pierre Constant N Nzoghe, Landry Missounga, Sophie Coniquet, Solange Ntsame, Rim Lakhmiri, Yahia Cherrah, Samira Serragui

{"title":"Stevens-Johnson Syndrome identified at the University Hospital Center of Libreville, Gabon: Four case reports.","authors":"Pierre Constant N Nzoghe, Landry Missounga, Sophie Coniquet, Solange Ntsame, Rim Lakhmiri, Yahia Cherrah, Samira Serragui","doi":"10.1177/09246479261479445","DOIUrl":"https://doi.org/10.1177/09246479261479445","url":null,"abstract":"BackgroundStevens-Johnson Syndrome (SJS) is a rare and severe drug-induced cutaneous reaction. However, clinical and economic data regarding its management remain poorly documented in Gabon. Therefore, this study aimed to describe the clinical characteristics, drug causality assessment, therapeutic management, and direct medical costs of four confirmed cases of SJS managed at the Libreville University Hospital Center (CHUL).Case reportFour confirmed cases of SJS related respectively to lidocaine, allopurinol, amoxicillin/clavulanic acid, and flucloxacillin were identified. Drug causality assessment, performed using the French causality assessment method, the World Health Organization (WHO) scale, and the ALDEN algorithm, indicated a probable causal relationship in all cases. SCORTEN scores ranged from 0 to 1, corresponding to an estimated mortality rate of 3.2%. Therapeutic management was based on symptomatic and supportive treatment, including Polaramine, Solumedrol, Dacryoserum, eosin solution, Fucithalmic, sodium bicarbonate, Fungizone, Dexeryl, ciprofloxacin, and Exomuc, with favorable clinical outcomes observed in all patients. The mean direct medical cost of management was estimated at 225,089 CFA francs (343.14 €), with a total cost of 860,355 CFA francs (1311.60 €) for the four cases.ConclusionSJS remains a severe dermatological emergency associated with substantial management costs despite favorable clinical outcomes. These findings highlight the importance of strengthening pharmacovigilance activities and the prevention of serious adverse drug reactions.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261479445"},"PeriodicalIF":0.8,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148805558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perception of adult males on late dinner and development of metabolic syndrome: A single-centered study from Ghana. 成年男性对晚晚餐的认知与代谢综合征的发展：一项来自加纳的单中心研究。

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-08-18 DOI: 10.1177/09246479261478753

Ofosuhene Edwin Kyei, Amoah Michael Kyei

{"title":"Perception of adult males on late dinner and development of metabolic syndrome: A single-centered study from Ghana.","authors":"Ofosuhene Edwin Kyei, Amoah Michael Kyei","doi":"10.1177/09246479261478753","DOIUrl":"https://doi.org/10.1177/09246479261478753","url":null,"abstract":"Metabolic syndrome (MetS) is increasingly prevalent due to sedentary lifestyles and late dinners in Ghana. This study in Ga North Municipal, Accra-Ghana, used an observational cross-sectional design involving 198 adult males. Findings indicated that 77.3% had knowledge on late dinners and perceived it as a harmful health effect, while 57.5% defined MetS as a cluster of diseases from metabolic activity fluctuations. Key risk factors identified included obesity (89.4%), alcohol consumption (86.4%), physical inactivity (88.9%), high salt intake (86.4%), and late dinner (89.9%). Despite this understanding, 78.8% exhibited poor prevention efforts, with 67.2% resistant to exercise and 56.6% not participating in regular health screenings. Respondents with higher educational level were more likely to have knowledge on late dinner and metabolic syndrome than those with lower educational level. The study identified a significant high level of knowledge on contributing factors of late dinners as a harmful habit in male adults. The study recommends heightened public awareness to promote prevention behaviors like exercise, dietary modification, and frequent health screenings.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261478753"},"PeriodicalIF":0.8,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148805550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative risk of new-onset diabetes between pravastatin and commonly used statins: A systematic review and meta-analysis. 普伐他汀与常用他汀类药物对新发糖尿病风险的比较：一项系统综述和荟萃分析。

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-08-18 DOI: 10.1177/09246479261476847

Harmanjit Singh, Gurleen Kaur, Parul Kaushal

{"title":"Comparative risk of new-onset diabetes between pravastatin and commonly used statins: A systematic review and meta-analysis.","authors":"Harmanjit Singh, Gurleen Kaur, Parul Kaushal","doi":"10.1177/09246479261476847","DOIUrl":"https://doi.org/10.1177/09246479261476847","url":null,"abstract":"IntroductionStatin therapy has been associated with an increased risk of new-onset diabetes mellitus (NODM). This systematic review and meta-analysis compared the risk of NODM between pravastatin and two commonly used statins.MethodsWe searched PubMed/MEDLINE, EMBASE, CENTRAL, and ClinicalTrials.gov from inception to May 23, 2024. Original studies comparing pravastatin with atorvastatin and/or rosuvastatin were included. Risk of bias was assessed using established, study-design-specific tools. Data were pooled using a random-effects model implemented in RevMan version 5.4.1. Statistical heterogeneity was assessed using the I2 statistic.ResultsEighteen studies were included, of which ten contributed to the meta-analysis. The comparison of pravastatin versus atorvastatin (10 studies; N = 95,276 vs 490,905) yielded a pooled risk ratio (RR) of 1.01 (95% CI: 0.77-1.32; I2 = 98%). Pravastatin versus rosuvastatin (9 studies; N = 92,853 vs 114,718) yielded a pooled RR of 1.12 (95% CI: 0.85-1.47; I2 = 96%).ConclusionPravastatin did not demonstrate a lower risk of NODM when compared with atorvastatin or rosuvastatin; nevertheless, further research remains warranted.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261476847"},"PeriodicalIF":0.8,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148805539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reframing risk management for AI-enabled medical devices: A dual-layer risk governance framework. 重构人工智能医疗设备的风险管理：双层风险治理框架。

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-08-13 DOI: 10.1177/09246479261477226

Pujitha Gourabathini

{"title":"Reframing risk management for AI-enabled medical devices: A dual-layer risk governance framework.","authors":"Pujitha Gourabathini","doi":"10.1177/09246479261477226","DOIUrl":"10.1177/09246479261477226","url":null,"abstract":"BackgroundAI-enabled medical devices introduce dynamic, data-dependent risks that challenge traditional safety-risk management frameworks. While ISO 14971, AAMI CR34971, and the EU Artificial Intelligence Act each address elements of device safety and algorithmic governance, they remain fragmented when applied. This review examines conceptual and operational gaps in current approaches and proposes an integrated governance model for AI-specific safety-risk management.MethodsA structured narrative review was conducted using PubMed, IEEE Xplore, Google Scholar, and regulatory repositories. Eligibility criteria focused on addressing AI-specific safety-risk management, regulatory obligations, or risk-analysis methodologies. A total of 19 academic studies and regulatory sources met inclusion criteria. Data were charted using JBI, AACODS, and normative appraisal categories, and synthesized to identify cross-cutting themes and gaps.ResultsThe review identified persistent challenges in linking AI-specific hazards to safety-risk evaluation, determining adequacy of risk controls, integrating algorithmic-risk obligations with ISO 14971 processes, and operationalizing lifecycle monitoring under the EU AI Act. Existing frameworks address components of AI risk but lack a unified operational pathway.ConclusionsAn integrated governance model is proposed to align AI-specific risk identification with established medical-device safety frameworks. This synthesis provides regulators, manufacturers, and professionals with a clearer, more actionable approach to managing AI-related safety risks.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261477226"},"PeriodicalIF":0.8,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148727111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient safety and risk management units in primary care: A qualitative study of healthcare providers' perspectives. 初级保健中的患者安全和风险管理单位：医疗保健提供者观点的定性研究。

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-08-13 DOI: 10.1177/09246479261477229

Ariela Popper-Giveon, Yael Keshet, Tamar Adar

{"title":"Patient safety and risk management units in primary care: A qualitative study of healthcare providers' perspectives.","authors":"Ariela Popper-Giveon, Yael Keshet, Tamar Adar","doi":"10.1177/09246479261477229","DOIUrl":"10.1177/09246479261477229","url":null,"abstract":"BackgroundPrimary care accounts for more than half of all adverse events leading to patient harm. Unique patient safety and risk management (PSRM) units have been operating in health maintenance organizations (HMOs) in Israel.ObjectiveTo explore healthcare providers' perspectives regarding the tasks, accomplishments, and recommendations concerning these PSRM units.MethodsIn-depth qualitative interviews were conducted with 40 healthcare community providers: 10 family physicians, 10 specialist physicians, 10 nurses, and 10 pharmacists.FindingsInterviewees identified two of the unit's main benefits and roles: learning from adverse events and providing backing in litigation cases. They emphasized four of the unit's accomplishments: sharing lessons learned from adverse event reports; addressing inquiries regarding clinic practice; instructing physicians on how to improve the accuracy of medical record documentation; and providing a user-friendly reporting procedure. They proposed several practices for promoting the reporting of adverse events.ConclusionsThe study suggests that embedded PSRM units promote the principles of Just Culture and encourage the reporting and discussion of adverse events. It outlines recommendations for practice and policy to support the optimization of PSRM units in primary care. The Israeli PSRM unit may offer an internationally relevant model for strengthening patient safety culture.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261477229"},"PeriodicalIF":0.8,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148724122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guillain-Barré syndrome complicated by myocarditis and acute kidney injury after maltose-based IVIG treatment: A case report. 麦芽糖类IVIG治疗后吉兰-巴勒综合征并发心肌炎和急性肾损伤1例。

IF 0.8

The International journal of risk & safety in medicine Pub Date : 2026-08-12 DOI: 10.1177/09246479261476841

Anjusha K Johnson, Joby Thomas Mammen, Mary Priya, Dharini Bhoopathi

{"title":"Guillain-Barré syndrome complicated by myocarditis and acute kidney injury after maltose-based IVIG treatment: A case report.","authors":"Anjusha K Johnson, Joby Thomas Mammen, Mary Priya, Dharini Bhoopathi","doi":"10.1177/09246479261476841","DOIUrl":"https://doi.org/10.1177/09246479261476841","url":null,"abstract":"BackgroundAcute Inflammatory Demyelinating Polyradiculoneuropathy (AIDP), the most common form of Guillain-Barré Syndrome (GBS), may rarely be complicated by myocarditis, which results from an inflammatory or autoimmune response. Conversely, acute kidney injury (AKI), caused by osmotic nephrosis, is an uncommon adverse effect associated with maltose-based intravenous immunoglobulin (IVIG) therapy, a common treatment for GBS.Case presentationA 41-year-old diabetic male diagnosed with AIDP received maltose-based IVIG. After 75 g administration, he developed flu-like symptoms and AKI, followed by signs of myocarditis, including elevated troponin, reduced ejection fraction, and ECG changes. IVIG was discontinued early due to these adverse effects. The patient required ICU care and hemofiltration but recovered with supportive treatment.ConclusionThis case highlights myocarditis as a rare complication of GBS and demonstrates that IVIG, while essential in treatment, even though maltose based, can lead to serious adverse effects including AKI, particularly in high-risk patients.","PeriodicalId":520800,"journal":{"name":"The International journal of risk & safety in medicine","volume":" ","pages":"9246479261476841"},"PeriodicalIF":0.8,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148715214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0