Sleep & breathing = Schlaf & Atmung最新文献

{"title":"The burden of narcolepsy symptoms from patients' perspective: a narrative qualitative study.","authors":"Jan Hlodak, Andrea Madarasova Geckova, Zuzana Dankulincova Veselska, Eva Feketeova","doi":"10.1007/s11325-025-03407-y","DOIUrl":"10.1007/s11325-025-03407-y","url":null,"abstract":"<p><strong>Background: </strong>Narcolepsy is characterized by excessive daytime sleepiness (EDS) and, in type one, cataplexy, often accompanied by disrupted nocturnal sleep, parasomnias, and other impairments. This study aims to explore patients' perceptions and emotional experiences of these symptoms.</p><p><strong>Methods: </strong>A qualitative study was conducted using narrative semi-structured interviews with 25 narcolepsy patients, guided by a structure approved by a multidisciplinary expert board. The interviews, conducted at the patients' homes or hospitals, were transcribed, inductively analyzed to develop a codebook, and subjected to thematic analysis.</p><p><strong>Results: </strong>The onset and manifestation were key themes for each symptom. EDS was often described as \"microsleeps\" or \"shutting off,\" causing embarrassment when occurring publicly and influenced by factors such as the weather, seasons, or menstruation. Cataplexy was commonly triggered by positive emotions or situations, including sexual intercourse, with patients often suppressing emotions to prevent episodes, leading to misinterpretations by others as drunkenness. Nocturnal sleep disturbances, including vivid dreams, nightmares, sleep paralysis, and hallucinations, led to negative emotional experiences. Overall, narcolepsy symptoms significantly impacted patients' emotional well-being.</p><p><strong>Conclusion: </strong>The burden of narcolepsy is deeply tied to patients' perceptions and emotional experiences, significantly affecting their quality of life, yet few studies have used qualitative approaches to explore their perspectives.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"231"},"PeriodicalIF":2.0,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12222228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supine position-related obstructive sleep apnea in children: insights from the Childhood Adenotonsillectomy Trial.","authors":"Siyu Dai, Ming Yang, Chun Ting Au, Nobel Tsz Kin Yuen, Yuzheng Zhang, Agatha Tang, Michelle Wai Ling Yu, Albert Martin Li, Kate Ching Ching Chan","doi":"10.1007/s11325-025-03393-1","DOIUrl":"10.1007/s11325-025-03393-1","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to examine the effectiveness of adenotonsillectomy (AT) among pediatric obstructive sleep apnea (OSA) patients with and without supine position-related OSA (POSA) and explore the stability of this subtype over time.</p><p><strong>Methods: </strong>Data from the Childhood Adenotonsillectomy Trial (CHAT) were analyzed. Children with OSA were randomized to early AT (EAT) or watchful waiting with supportive care (WWSC). Polysomnographic and health outcomes were assessed at baseline and 7 months. POSA was defined as a supine obstructive apnea-hypopnea index (OAHI) ≥ 2× non-supine OAHI, with ≥ 30 min spent in each position.</p><p><strong>Results: </strong>Among 354 patients (mean age: 6.97 ± 1.39 years; male: 48.1%), 47.2% had POSA at baseline. Compared to non-POSA, children with POSA exhibited lower baseline OAHI [3.77 (2.48, 7.71) vs. 5.42 (3.03, 9.47) events/h, p = 0.006], longer rapid eye movement (REM) sleep in the supine position (p = 0.05), shorter REM sleep in non-supine position (p = 0.005), and fewer allergic conditions (37.7% vs. 48.4%, p = 0.05). Generalized linear models showed AHI reduction was associated with randomization grouping (p < 0.001) but not POSA status (p = 0.10). Our restricted cubic splines further supported this finding. Notably, in the WWSC group, POSA classification changed for half of the patients over 7 months, with changes in non-supine OAHI as a significant indicator.</p><p><strong>Conclusion: </strong>AT is effective in managing childhood OSA regardless of POSA status. The observed dynamic nature of POSA warrants future research into its pathophysiology and natural history.</p><p><strong>Clinical trial registration: </strong>Childhood Adenotonsillectomy Study for Children with OSAS (CHAT), Clinical Trial Identifier NCT00560859.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"230"},"PeriodicalIF":2.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of Chaihu plus Longgu Muli decoction combined with Estazolam in the treatment of insomnia: a meta-analysis.","authors":"Mengfan Li, Zhaolian Cai, Xiaoyong Zhong, Bin Chen, Haiyan Zheng, Shangzhong Chen, Li Lin, Hui Liang, Zhizhen Liu, Jing Luo","doi":"10.1007/s11325-025-03404-1","DOIUrl":"10.1007/s11325-025-03404-1","url":null,"abstract":"<p><strong>Background: </strong>Insomnia is a major sleeping disorder that affects the quality of life and overall health in a tremendous way. Those pharmacological therapies of insomnia, which are typically applied, i.e., benzodiazepines, may result in side effects that are rather dangerous, i.e., dependency and the decline of the cognitive status. Chaihu plus Longgu Muli decoction is a traditional Chinese herbal formula (TCM) which has been used in the treatment of insomnia and can be used as a safer alternative or complementary approach in the treatment of this ailment.</p><p><strong>Methos: </strong>PubMed, Embase, Cochrane library, CNKI, Wanfang, CQVIP and CBM databases have been searched in our meta-analysis since the establishment of the databases to July 2024. The studies containing the combination of Chaihu Longgu Muli decoction and Estazolam in treating insomnia were to be included in the proposed study without taking into consideration the published literatures, unpublished literatures, those which contain in-complete or inadequate information, animal experiments, literature synthesis and the systematic study. Data analysis was done on the STATA 15.1.</p><p><strong>Results: </strong>The meta-analysis revealed that the blend of Chaihu plus Longgu Muli decoction and Estazolam used to be extra potent than Estazolam treatment in enhancing the quality of sleep, as indicated by higher effective rates (RR = 1.29, 95% CI: 1.20-1.38, P = 0.000) and lower Pittsburgh Sleep Quality Index (PSQI) scores (WMD=-2.98, 95% CI: -4.06 to -1.90, P = 0.000). Also, lesser Traditional Chinese Medicine (TCM) syndrome scores followed the mixture therapy (WMD=-4.04, 95% CI: -4.38 to -3.70, P = 0.000) and reduced incidence of adverse events (RR = 0.35, 95% CI: 0.16-0.76, P = 0.000).</p><p><strong>Conclusion: </strong>The combination of Chaihu plus Longgu Muli decoction and Estazolam is more effective and safer than Estazolam alone in treating insomnia. This integrative approach could offer a promising alternative for patients seeking effective and safer treatment options for insomnia.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"229"},"PeriodicalIF":2.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12206178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Xerostomia in obstructive sleep apnea: a cross-cultural validation and utilization of the multidisciplinary salivary gland society questionnaire.","authors":"Reza Erfanian, Raha Zamani, Seyedeh Atiyeh Moazeni, Reihaneh Heidari","doi":"10.1007/s11325-025-03396-y","DOIUrl":"10.1007/s11325-025-03396-y","url":null,"abstract":"<p><strong>Purpose: </strong>Dry mouth is one of the most common complaints of obstructive sleep apnea (OSA) patients. The extent of the relationship between OSA severity and subjective xerostomia is not yet fully understood.</p><p><strong>Methods: </strong>The Multidisciplinary Salivary Gland Society Questionnaire (MSGS) was administered to 120 patients with OSA. All patients underwent polysomnography and a comprehensive physical exam. The association of MSGS scores with objective and subjective OSA measures was evaluated.</p><p><strong>Results: </strong>A significant correlation was observed between the xerostomia subscale of MSGS and the percent of sleep time spent with oxygen saturation below 90% (Spearman's ρ: 0.211, p = 0.028), oxygen saturation nadir (Spearman's ρ: -0.265, p = 0.005) and Friedman tonsil grade (Spearman's ρ: 0.333, p = 0.001). A significant association between xerostomia and Modified Cormack-Lehane endoscopic score of larynx (Spearman's ρ: -0.201, p = 0.042) and a near significant association between xerostomia and endoscopic vertical phenotype of the palate (Spearman's ρ: -0.194, p = 0.050) were observed. Tonsil grade was also a significant predictor of xerostomia and the total MSGS in multivariate regression analysis (correlation coefficient = 3.3, p = 0.001, and correlation coefficient = 2.6, p = 0.011; respectively). Age was inversely associated with the sialadenitis score, in both univariate and multivariate analyses (correlation coefficient = -3.2, p = 0.002).</p><p><strong>Conclusion: </strong>OSA patients with tonsillar hypertrophy and severe sleep hypoxia have higher rates of subjective xerostomia. Further studies are needed to investigate the bidirectional relationship between sleep apnea and xerostomia.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"228"},"PeriodicalIF":2.0,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"cardiovascular risks in non-dipper OSA patients: insights from ABPM, echocardiography, and Holter monitoring\".","authors":"Amnuay Kleebayoon, Viroj Wiwanitkit","doi":"10.1007/s11325-025-03395-z","DOIUrl":"10.1007/s11325-025-03395-z","url":null,"abstract":"","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"227"},"PeriodicalIF":2.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstructive sleep apnea is a risk factor for incident COVID-19 infection.","authors":"Stuart F Quan, Matthew D Weaver, Mark É Czeisler, Laura K Barger, Lauren A Booker, Mark E Howard, Melinda L Jackson, Christine F McDonald, Anna Ridgers, Rebecca Robbins, Prerna Varma, Shantha M W Rajaratnam, Charles A Czeisler","doi":"10.1007/s11325-025-03401-4","DOIUrl":"10.1007/s11325-025-03401-4","url":null,"abstract":"","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"226"},"PeriodicalIF":2.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of sleep bruxism on oral health-related quality of life in children: a systematic review and meta-analysis of observational studies.","authors":"Milena Andrade Araújo Costa, Raquel Souza Marques, Marilia Leão Goettems, Flávio Fernando Demarco, Paulo Ricardo Martins-Filho","doi":"10.1007/s11325-025-03394-0","DOIUrl":"10.1007/s11325-025-03394-0","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review and meta-analysis aimed to synthesize evidence on the impact of sleep bruxism on oral health-related quality of life (OHRQoL) in children.</p><p><strong>Methods: </strong>A comprehensive literature search was conducted in PubMed, Scopus, Embase, and Web of Science, without language restrictions. Observational studies evaluating the association between sleep bruxism and OHRQoL in children (aged 0-12 years) were included. Risk of bias was assessed using the JBI Critical Appraisal Checklist for Analytical Cross-Sectional Studies. Pooled odds ratios (ORs) and mean differences (MDs) with 95% confidence intervals (CIs) were calculated using random-effects models. Studies not eligible for meta-analysis were described narratively.</p><p><strong>Results: </strong>Eight studies were included in the systematic review, and four in the meta-analysis, encompassing data from 968 children. Meta-analysis demonstrated that sleep bruxism was significantly associated with impaired OHRQoL (OR = 1.99; 95% CI: 1.09-3.65), with greater impacts observed in the symptom (MD = 0.43; 95% CI: 0.17-0.69) and functional domains (MD = 1.00; 95% CI: 0.08-1.92). No significant association was observed for family-related outcomes (OR = 1.87; 95% CI: 0.60-5.82). Among studies not included in the meta-analysis, findings were inconsistent, highlighting methodological variability.</p><p><strong>Conclusions: </strong>Sleep bruxism adversely affects children's OHRQoL, especially in domains related to symptoms and functional limitations. These findings highlight the need for early identification and individualized management to mitigate its impact. Longitudinal studies are warranted to elucidate causality and assess broader psychosocial outcomes.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"223"},"PeriodicalIF":2.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between vitamin D level and sleep quality in the elderly population: a prospective cohort study.","authors":"Wei-Hsuan Lee, Yu-Hsi Chen, Tsai-Yu Wang, Wen-Jui Chang, Ting-Wei Liao, Wei-Syun Hung, Shih-Wei Lin, Ning-Hung Chen, Ji-Tseng Fang, Li-Pang Chuang","doi":"10.1007/s11325-025-03398-w","DOIUrl":"10.1007/s11325-025-03398-w","url":null,"abstract":"<p><strong>Purpose: </strong>Vitamin D is essential not only for skeletal health but also for regulating sleep. Recent studies suggest a link between vitamin D deficiency and poor sleep quality, including lower sleep efficiency and shorter sleep duration. This study aimed to investigate the relationship between sleep quality and serum vitamin D levels in healthy elderly individuals.</p><p><strong>Methods: </strong>This study examined the association between serum vitamin D levels and sleep quality in individuals aged 60 years and above residing in Taipei's Health & Culture Village and Active Aging Center. A total of 465 participants were enrolled, with those exhibiting specific organ abnormalities or dysfunctions excluded. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), and vitamin D levels were measured using enzyme-linked immunosorbent assay (ELISA). The relationships between vitamin D levels and PSQI scores were analyzed, with a focus on the daytime dysfunction component of the PSQI.</p><p><strong>Results: </strong>Among the seven domains of the PSQI, the daytime dysfunction domain had the strongest statistical association with serum vitamin D levels (p = 0.044). Participants without daytime dysfunction had significantly higher vitamin D levels than did those with daytime dysfunction (p = 0.04). No significant associations were detected between vitamin D levels and other factors, such as sex or age.</p><p><strong>Conclusions: </strong>Higher serum vitamin D levels are associated with better sleep quality in elderly individuals, particularly in those without daytime dysfunction. This finding highlights the potential importance of maintaining adequate vitamin D levels to promote healthy sleep patterns in older adults.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"225"},"PeriodicalIF":2.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular density changes in retina and optic nerve in obstructive sleep apnea syndrome cases.","authors":"Turker Oba, Berkay Hasan Arman, Meryem Feyza Cicek, Feyza Onder","doi":"10.1007/s11325-025-03397-x","DOIUrl":"10.1007/s11325-025-03397-x","url":null,"abstract":"","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"224"},"PeriodicalIF":2.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of self-rated health status on sleep disturbance among elderly diabetics: finding from the indonesian family life survey.","authors":"Yuni Asri, Hsiao-Yean Chiu, Faizul Hasan","doi":"10.1007/s11325-025-03390-4","DOIUrl":"10.1007/s11325-025-03390-4","url":null,"abstract":"<p><strong>Objective: </strong>Insufficient sleep quality is common among elderly adults with diabetes and can exacerbate existing health issues. Psychological factors, particularly self-assessed health status, play a key role in influencing sleep quality. This study aimed to examine the relationship between self-rated health status and sleep quality in older adults with diabetes.</p><p><strong>Methods: </strong>Data were analyzed from the Indonesian Family Life Survey (IFLS-5), conducted between late 2014 and early 2015. Multivariate logistic regression analysis was conducted to identify key factors associated with sleep quality in elderly diabetics, with odds ratios (ORs) and 95% confidence intervals (CIs) reported.</p><p><strong>Results: </strong>The study found that 15.2% of elderly participants reported poor sleep quality. A significant association was observed between poor self-rated health and diminished sleep quality (ORs = 0.15; 95% CI = 0.49-0.47, P < 0.05), indicating that older adults with diabetes who perceive their health as poor are more likely to experience sleep disturbances. The findings emphasize the importance of improving health perceptions in this population through strategies like psychological support, health education, and stress management.</p><p><strong>Conclusion: </strong>Sleep quality is a critical component of overall health. Addressing psychological and social factors that impact sleep may help mitigate the negative effects of poor sleep on the health of elderly adults with diabetes. Targeted interventions could improve health outcomes and enhance quality of life for this vulnerable group.</p>","PeriodicalId":520777,"journal":{"name":"Sleep & breathing = Schlaf & Atmung","volume":"29 4","pages":"222"},"PeriodicalIF":2.0,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}