Research (Washington, D.C.)最新文献

{"title":"Tunable Multicolor Fluorescence of Perovskite-Based Composites for Optical Steganography and Light-Emitting Devices.","authors":"Kewei Ma,&nbsp;Qingfeng Gui,&nbsp;Cihui Liu,&nbsp;Yunyi Yang,&nbsp;Fangjian Xing,&nbsp;Yunsong Di,&nbsp;Xiaoming Wen,&nbsp;Baohua Jia,&nbsp;Zhixing Gan","doi":"10.34133/2022/9896548","DOIUrl":"https://doi.org/10.34133/2022/9896548","url":null,"abstract":"<p><p>Multicolor fluorescence of mixed halide perovskites enormously enables their applications in photonics and optoelectronics. However, it remains an arduous task to obtain multicolor emissions from perovskites containing single halogen to avoid phase segregation. Herein, a fluorescent composite containing Eu-based metal-organic frameworks (MOFs), 0D Cs₄PbBr₆, and 3D CsPbBr₃ is synthesized. Under excitations at 365 nm and 254 nm, the pristine composite emits blue (B) and red (R) fluorescence, which are ascribed to radiative defects within Cs₄PbBr₆ and ⁵D₀→⁷F_J transitions of Eu³⁺, respectively. Interestingly, after light soaking in the ambient environment, the blue fluorescence gradually converts into green (G) emission due to the defect repairing and 0D-3D phase conversion. This permanent and unique photochromic effect enables anticounterfeiting and microsteganography with increased security through a micropatterning technique. Moreover, the RGB luminescence is highly stable after encapsulation by a transparent polymer layer. Thus, trichromatic light-emitting modules are fabricated by using the fluorescent composites as color-converting layers, which almost fully cover the standard color gamut. Therefore, this work innovates a strategy for construction of tunable multicolor luminescence by manipulating the radiative defects and structural dimensionality.</p>","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9896548"},"PeriodicalIF":11.0,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33491185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Broadband Insulator-Based Dynamic Diode with Ultrafast Hot Carriers Process.","authors":"Runjiang Shen,&nbsp;Yanghua Lu,&nbsp;Xutao Yu,&nbsp;Qi Ge,&nbsp;Huiming Zhong,&nbsp;Shisheng Lin","doi":"10.34133/2022/9878352","DOIUrl":"https://doi.org/10.34133/2022/9878352","url":null,"abstract":"<p><p>The excitation, rebound, and transport process of hot carriers (HCs) inside dynamic diode (DD) based on insulators has been rarely explored due to the original stereotyped in which it was thought that the insulators are nonconductive. However, the carrier dynamics of DD is totally different from the static diode, which may bring a subverting insight of insulators. Herein, we discovered insulators could be conductive under the framework of DD; the HC process inside the rebounding procedure caused by the disappearance and reestablishment of the built-in electric field at the interface of insulator/semiconductor heterostructure is the main generation mechanism. This type of DD can response fast up to 1 <i>μ</i>s to mechanical excitation with an output of ~10 V, showing a wide band frequency response under different input frequencies from 0 to 40 kHz. It can work under extreme environments; various applications like underwater communication network, self-powered sensor/detector in the sea environment, and life health monitoring can be achieved.</p>","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9878352"},"PeriodicalIF":11.0,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33491610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Superlow Power Consumption Artificial Synapses Based on WSe₂ Quantum Dots Memristor for Neuromorphic Computing.","authors":"Zhongrong Wang,&nbsp;Wei Wang,&nbsp;Pan Liu,&nbsp;Gongjie Liu,&nbsp;Jiahang Li,&nbsp;Jianhui Zhao,&nbsp;Zhenyu Zhou,&nbsp;Jingjuan Wang,&nbsp;Yifei Pei,&nbsp;Zhen Zhao,&nbsp;Jiaxin Li,&nbsp;Lei Wang,&nbsp;Zixuan Jian,&nbsp;Yichao Wang,&nbsp;Jianxin Guo,&nbsp;Xiaobing Yan","doi":"10.34133/2022/9754876","DOIUrl":"https://doi.org/10.34133/2022/9754876","url":null,"abstract":"<p><p>As the emerging member of zero-dimension transition metal dichalcogenide, WSe₂ quantum dots (QDs) have been applied to memristors and exhibited better resistance switching characteristics and miniaturization size. However, low power consumption and high reliability are still challenges for WSe₂ QDs-based memristors as synaptic devices. Here, we demonstrate a high-performance, superlow power consumption memristor device with the structure of Ag/WSe₂ QDs/La_0.3Sr_0.7MnO₃/SrTiO₃. The device displays excellent resistive switching memory behavior with a <i>R</i> _OFF/<i>R</i> _ON ratio of ~5 × 10³, power consumption per switching as low as 0.16 nW, very low set, and reset voltage of ~0.52 V and~ -0.19 V with excellent cycling stability, good reproducibility, and decent data retention capability. The superlow power consumption characteristic of the device is further proved by the method of density functional theory calculation. In addition, the influence of pulse amplitude, duration, and interval was studied to gradually modulating the conductance of the device. The memristor has also been demonstrated to simulate different functions of artificial synapses, such as excitatory postsynaptic current, spike timing-dependent plasticity, long-term potentiation, long-term depression, and paired-pulse facilitation. Importantly, digit recognition ability based on the WSe₂ QDs device is evaluated through a three-layer artificial neural network, and the digit recognition accuracy after 40 times of training can reach up to 94.05%. This study paves a new way for the development of memristor devices with advanced significance for future low power neuromorphic computing.</p>","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9754876"},"PeriodicalIF":11.0,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33491187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Pulse Emission Spectroscopy Method to Characterize Xylem Conduits in Plant Stems.","authors":"Satadal Dutta,&nbsp;Zhiyi Chen,&nbsp;Elias Kaiser,&nbsp;Priscilla Malcolm Matamoros,&nbsp;Peter G Steeneken,&nbsp;Gerard J Verbiest","doi":"10.34133/2022/9790438","DOIUrl":"https://doi.org/10.34133/2022/9790438","url":null,"abstract":"<p><p>Although it is well known that plants emit acoustic pulses under drought stress, the exact origin of the waveform of these ultrasound pulses has remained elusive. Here, we present evidence for a correlation between the characteristics of the waveform of these pulses and the dimensions of xylem conduits in plants. Using a model that relates the resonant vibrations of a vessel to its dimension and viscoelasticity, we extract the xylem radii from the waveforms of ultrasound pulses and show that these are correlated and in good agreement with optical microscopy. We demonstrate the versatility of the method by applying it to shoots of ten different vascular plant species. In particular, for <i>Hydrangea quercifolia</i>, we further extract vessel element lengths with our model and compare them with scanning electron cryomicroscopy. The ultrasonic, noninvasive characterization of internal conduit dimensions enables a breakthrough in speed and accuracy in plant phenotyping and stress detection.</p>","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9790438"},"PeriodicalIF":11.0,"publicationDate":"2022-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9513830/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33491612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanotechnology Powered CRISPR-Cas Systems for Point of Care Diagnosis and Therapeutic.","authors":"Chen-Zhong Li,&nbsp;Tony Y Hu","doi":"10.34133/2022/9810237","DOIUrl":"https://doi.org/10.34133/2022/9810237","url":null,"abstract":"","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9810237"},"PeriodicalIF":11.0,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33482789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Engineering Stem Cell Recruitment and Osteoinduction via Bioadhesive Molecular Mimics to Improve Osteoporotic Bone-Implant Integration.","authors":"Jiaxiang Bai,&nbsp;Gaoran Ge,&nbsp;Qing Wang,&nbsp;Wenming Li,&nbsp;Kai Zheng,&nbsp;Yaozeng Xu,&nbsp;Huilin Yang,&nbsp;Guoqing Pan,&nbsp;Dechun Geng","doi":"10.34133/2022/9823784","DOIUrl":"https://doi.org/10.34133/2022/9823784","url":null,"abstract":"<p><p>For patients with osteoporosis, the therapeutic outcomes of osteoimplants are substantially affected by the impaired proliferation, migration, and osteogenic differentiation abilities of bone marrow mesenchymal stem cells (BMSCs). To improve bone-implant integration in osteoporotic condition, here we reported a one-step biomimetic surface strategy to introduce BMSC recruiting and osteoinductive abilities onto metallic osteoimplants. In our design, the bioadhesive molecular peptide mimic inspired by mussel foot proteins (Mfps) was used as molecular bridging for surface functionalization. Specifically, a BMSC-targeting peptide sequence (E7) and an osteogenic growth peptide (Y5) were grafted onto the titanium implant surfaces through a mussel adhesion mechanism. We found that a rational E7/Y5 feeding ratio could lead to an optimal dual functionalization capable of not only significantly improving the biocompatibility of the implant but also enabling it to recruit endogenous BMSCs for colonization, proliferation, and osteogenic differentiation. Mechanistically, the E7-assisted in situ recruitment of endogenous BMSCs as well as the enhanced interfacial osteogenesis and osteointegration was associated with activation of the C-X-C chemokine receptor type 4 (CXCR4) receptor on the cell surface and promotion of stromal cell-derived factor (SDF-1<i>α</i>) autocrine secretion. We anticipated that rational dual-functional surfaces through bioadhesive molecular mimics will provide a simple, effective, nonimmunogenic, and safe means to improve the clinical outcomes of intraosseous implants, especially under osteoporotic conditions.</p>","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9823784"},"PeriodicalIF":11.0,"publicationDate":"2022-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33482787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photothermal Nano-Vaccine Promoting Antigen Presentation and Dendritic Cells Infiltration for Enhanced Immunotherapy of Melanoma via Transdermal Microneedles Delivery.","authors":"Jiaojiao Zhu,&nbsp;Ruimin Chang,&nbsp;Benliang Wei,&nbsp;Yao Fu,&nbsp;Xiang Chen,&nbsp;Hong Liu,&nbsp;Wenhu Zhou","doi":"10.34133/2022/9816272","DOIUrl":"https://doi.org/10.34133/2022/9816272","url":null,"abstract":"<p><p>Immunotherapy has demonstrated the potential to cure melanoma, while the current response rate is still unsatisfactory in clinics. Extensive evidence indicates the correlation between the efficacy and pre-existing T-cell in tumors, whereas the baseline T-cell infiltration is lacking in low-response melanoma patients. Herein, we demonstrated the critical contribution of dendritic cells (DCs) on melanoma survival and baseline T-cell level, as well as the efficacy of immunotherapy. Capitalized on this fact, we developed a photothermal nano-vaccine to simultaneously promote tumor antigens presentation and DCs infiltration for enhanced immunotherapy. The nano-vaccine was composed of polyserotonin (PST) core and tannic acid (TA)/Mn²⁺ coordination-based metal-organic-framework (MOF) shell for <i>β</i>-catenin silencing DNAzyme loading, which was further integrated into dissolving microneedles to allow noninvasive and transdermal administration at melanoma skin. The nano-vaccine could rapidly penetrate skin upon microneedles insertion and exert a synergistically amplified photothermal effect to induce immunogenic cell death (ICD). The MOF shell then dissociated and released Mn²⁺ as a cofactor to self-activate DNAzyme for <i>β</i>-catenin suppression, which in turn caused a persistent CCL4 excretion to promote the infiltration of DCs into the tumor. Meanwhile, the liberated PST core could effectively capture and facilitate tumor antigens presentation to DCs. As a result, potent antitumor efficacies were achieved for both primary and distal tumors without any extra treatment, indicating the great promise of such a nano-vaccine for on-demand personalized immunotherapy of melanoma.</p>","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9816272"},"PeriodicalIF":11.0,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33482788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remote Measurement of the Angular Velocity Vector Based on Vectorial Doppler Effect Using Air-Core Optical Fiber.","authors":"Zhenyu Wan, Yize Liang, Xi Zhang, Ziyi Tang, Liang Fang, Zelin Ma, Siddharth Ramachandran, Jian Wang","doi":"10.34133/2022/9839502","DOIUrl":"10.34133/2022/9839502","url":null,"abstract":"<p><p>Rotational Doppler effect has made tremendous development in both theoretical and applied research over the last decade. Different from the inertial thinking of focusing on the scalar field dominated by helical phase light, we have revealed a vectorial Doppler effect in our previous work, which is based on the spatially variant polarized light fields to simultaneously acquire the speed and direction of a target. Here, further, we propose a method to construct a flexible and robust velocimeter based on that novel effect by employing an air-core fiber with kilometer-length scale for remotely measuring the vectorial information of angular velocity in situ. In addition, we experimentally substantiate that the measurement system still has commendable accuracy in determining the direction of movement even when the air-core fiber is interfered by the external environment. The demonstrations prove the potential of vectorial Doppler effect in practical scenarios and remote measurements.</p>","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9839502"},"PeriodicalIF":10.7,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40371153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of Photoresponsive 3D Structures Based on Triphenylethylene Photochromic Building Blocks.","authors":"Xiayu Zhang,&nbsp;Fukang Liu,&nbsp;Beibei Du,&nbsp;Rongjuan Huang,&nbsp;Simin Zhang,&nbsp;Yunfei He,&nbsp;Hailan Wang,&nbsp;Jingjing Cui,&nbsp;Biao Zhang,&nbsp;Tao Yu,&nbsp;Wei Huang","doi":"10.34133/2022/9834140","DOIUrl":"https://doi.org/10.34133/2022/9834140","url":null,"abstract":"<p><p>Photoresponsive materials have been widely used in sensing, bioimaging, molecular switches, information storage, and encryption nowadays. Although a large amount of photoresponsive materials have been reported, the construction of these smart materials into precisely prescribed complex 3D geometries is rarely studied. Here we designed a novel photoresponsive material methyl methacrylate containing triphenylethylene (TrPEF₂-MA) that can be directly used for digital light processing (DLP) 3D printing. Based on TrPEF₂-MA, a series of photoresponsive 3D structures with reversible color switching under ultraviolet/visible light irradiations were fabricated. These complex photoresponsive 3D structures show high resolutions (50 <i>μ</i>m), excellent repeatability (25 cycles without fatigue), and tunable saturate color degrees. Multicomponent DLP 3D printing processes were also carried out to demonstrate their great properties in information hiding and information-carrying properties. This design strategy for constructing photoresponsive 3D structures is attractive in the area of adaptive camouflage, information hiding, information storage, and flexible electronics.</p>","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9834140"},"PeriodicalIF":11.0,"publicationDate":"2022-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9484832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33482790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design Strategy for Vulcanization Accelerator of Diphenylguanidine/Cyclodextrin Inclusion Complex for Natural Rubber Latex Foam with Enhancing Performance.","authors":"Wang Zhang,&nbsp;Liwei Lin,&nbsp;Junqiang Guo,&nbsp;Ming Wu,&nbsp;Sumin Park,&nbsp;Hang Yao,&nbsp;Sun Ha Paek,&nbsp;Guowang Diao,&nbsp;Yuanzhe Piao","doi":"10.34133/2022/9814638","DOIUrl":"https://doi.org/10.34133/2022/9814638","url":null,"abstract":"<p><p>Vulcanization is an essential process to obtain high-performance rubber products. Diphenylguanidine (DPG) is often used as the secondary accelerator in the vulcanization process of natural rubber (NR) latex. However, DPG would make NR latex emulsion exhibit gelation, resulting in the negative vulcanization efficiency. In addition, exposure to DPG might lead to some physiological diseases during the production process of DPG doped NR latex. Hydroxypropyl-<i>β</i>-cyclodextrin (HP-<i>β</i>-CD) with the hydrophobic interior and hydrophilic exterior has the advantages of good water solubility, high bioavailability, reliable stability, and low toxicity. In this study, the inclusion complex of diphenylguanidine-hydroxypropyl-<i>β</i>-cyclodextrin (DPG-HP-<i>β</i>-CD) is prepared by ball milling with a host-guest molar ratio of 1 : 1, which has also been applied to the foaming process of NR latex. The mechanical properties of DPG-HP-<i>β</i>-CD inclusion complex/natural rubber latex foam (DPG-HP-<i>β</i>-CD/NRLF) have been significantly improved, including the tensile strength, elongation at break, hardness, compression set, resilience, and antiaging performance. Further, the usage of DPG has been reduced, leading to the reduction of toxicity and environmental hazards.</p>","PeriodicalId":520765,"journal":{"name":"Research (Washington, D.C.)","volume":" ","pages":"9814638"},"PeriodicalIF":11.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40372602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}