ORL; journal for oto-rhino-laryngology and its related specialties最新文献

{"title":"Presentation and publication rates among women and men at AAO-HNS meetings.","authors":"Marc A Cohen,&nbsp;Natasha Mirza,&nbsp;Kristel Dow,&nbsp;Soo Kim Abboud","doi":"10.1159/000345099","DOIUrl":"https://doi.org/10.1159/000345099","url":null,"abstract":"<p><strong>Objective: </strong>We attempted to assess the percentages of abstracts submitted to annual American Academy of Otolaryngology, Head and Neck Surgery (AAO-HNS) meetings from 2000 to 2004 by both women and men. We sought to determine the subsequent peer-reviewed overall publication rates for all submissions. We also studied trends of submission among female presenters and compared them to males.</p><p><strong>Study design: </strong>Cross-sectional study.</p><p><strong>Setting: </strong>Tertiary academic medical center.</p><p><strong>Methods: </strong>2,463 total abstracts presented between 2000 and 2004 were searched in the computerized databases Medline and Pubmed in 2008. The published articles were examined by reviewers to assess publication rate, time to publication, gender of authorship and subspecialty of publication.</p><p><strong>Results: </strong>1,413 (57.35%) posters and 1,051 (42.65%) oral presentations were presented from 2000 to 2004. Of the 1,413 posters presented, 275 (19.46%) were presented by female first authors. The female first-author poster publication rate was 33.81%, while the male first-author poster publication rate was 36.99% (p = 0.353). Of 1,051 oral presentations, 154 (14.65%) were presented by female first authors. The male first-author oral presentation publication rate was 60.98%, while the female first-author oral presentation publication rate was 59.09% (p = 0.657). There were no statistical differences in time to publication for posters (p = 0.796) or oral presentations (p = 0.737) between the genders. The majority of female first-author submissions involved pediatric (29.94%) and general (17.88%) otolaryngology.</p><p><strong>Conclusion: </strong>While women are increasingly drawn to otolaryngology, they represented less than 20% of total submissions at the annual AAO-HNS meetings from 2000 to 2004. Women more commonly submit poster than oral presentations. The eventual publication rates of abstracts and the average time to publication of presentations are equal between the genders.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"325-9"},"PeriodicalIF":1.3,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000345099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40216363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical appraisal of endoscopy with narrow-band imaging system in the evaluation and management of homogeneous oral leukoplakia.","authors":"Shih-Wei Yang,&nbsp;Yun-Shien Lee,&nbsp;Liang-Che Chang,&nbsp;Hui-Ping Chien,&nbsp;Tai-An Chen","doi":"10.1159/000336722","DOIUrl":"https://doi.org/10.1159/000336722","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the clinical usefulness of endoscopy with a narrow-band imaging (NBI) system for the evaluation and management of homogeneous oral leukoplakia.</p><p><strong>Methods: </strong>The chart records, morphology of vascular architecture of NBI, and histopathology of patients with homogeneous leukoplakia were retrospectively reviewed and analyzed.</p><p><strong>Results: </strong>A total of 160 patients, with an average age of 50.96 ± 10.25 years, were enrolled. In 35 cases of thin leukoplakia, only intraepithelium papillary capillary loop (IPCL) type I was shown by NBI, and only squamous hyperplasia was revealed pathologically. In 125 cases of thick leukoplakia, IPCL type I was found in 94, IPCL type II in 29, and IPCL type III in 2. The Kendall rank correlation between pathology and NBI images was significant (p < 0.0001).</p><p><strong>Conclusions: </strong>The dichotomous classification of homogeneous leukoplakia by NBI is meaningful, and endoscopy with the NBI system is a promising tool for the evaluation and management of homogeneous oral leukoplakia.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"102-9"},"PeriodicalIF":1.3,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000336722","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40160854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified endoscopic maxillary medial sinusotomy for sinonasal inverted papilloma with attachment to the anterior medial wall of maxillary sinus.","authors":"Chengshuo Wang,&nbsp;Demin Han,&nbsp;Luo Zhang","doi":"10.1159/000336739","DOIUrl":"https://doi.org/10.1159/000336739","url":null,"abstract":"<p><strong>Objectives: </strong>The endoscopic management of inverted papilloma (IP) has gained in popularity over the last 15 years. However, the appropriate management of lesions involving the anterior medial wall of the maxillary sinus still has to be determined.</p><p><strong>Methods: </strong>We performed a retrospective review of the surgical results for patients with IP attached to the anterior medial wall of the maxillary sinus in the Otolaryngology, Head and Neck Surgery Department, Beijing TongRen Hospital. The tumors were removed by using our surgical technique of modified endoscopic maxillary medial sinusotomy, which was defined as an extended endoscopic medial maxillectomy with preservation of the nasolacrimal duct and inferior turbinate. Sinus endoscopy was used to screen for disease after endoscopic resection and the clinical outcomes were analyzed.</p><p><strong>Results: </strong>A total of 7 patients (4 males and 3 females) were identified. Pre- and postoperative pathological examinations revealed inverted papilloma as the diagnosis. All tumors were defined as Krouse III lesions. There were no complications recorded as a result of surgery. All patients remain disease free with a mean follow-up of 35.7 months (range 20-68 months).</p><p><strong>Conclusion: </strong>Sinonasal IP with attachment to the anterior medial portion of the maxillary sinus can be treated successfully using modified endoscopic maxillary medial sinusotomy with preservation of the nasolacrimal duct and inferior turbinate.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"97-101"},"PeriodicalIF":1.3,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000336739","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40161901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Labyrinthotomy or vestibulotomy in anatomic and congenital variations of the oval window and facial nerve.","authors":"Khalid A Al-Mazrou,&nbsp;Yildirim A Bayazit","doi":"10.1159/000345714","DOIUrl":"https://doi.org/10.1159/000345714","url":null,"abstract":"<p><strong>Objective: </strong>To present the results of our experience with labyrinthotomy or vestibulotomy in cases where the oval window is blocked by the facial nerve and in the presence of bilateral congenital agenesis of the oval window, respectively.</p><p><strong>Study design: </strong>Retrospective analysis of the records of the patients operated in two different centers.</p><p><strong>Methods: </strong>Between 2007 and 2012, 5 ears of 4 patients who were operated on in two different clinics with a presumptive diagnosis of otosclerosis were included in the study. There were 3 female patients and 1 male. The ages ranged from 10 to 26 (mean 19 years). All patients had unilateral conductive hearing loss except 1 (10-year-old girl or patient 1). Pure tone averages were calculated at the frequencies 0.5, 1, 2 and 4 kHz both pre- and postoperatively according to the Committee on Hearing and Equilibrium 1995 Guidelines for the Evaluation of Results of Treatment of Conductive Hearing Loss. All patients underwent a middle ear exploration and postoperatively the initial audiological examination was performed after 6 months.</p><p><strong>Results: </strong>Retrospective analysis revealed that vestibulotomy or labyrinthotomy was performed in 5 ears of 4 patients. Postoperative dizziness was encountered in 2 patients who had vestibulotomy due to oval window agenesis, which ceased spontaneously at 1 month postoperatively. The perioperative period was otherwise uneventful. None of the patients had sensorineural hearing loss or deterioration of hearing. There was a significant improvement in hearing after the operation. A 28-dB improvement in the mean air conduction pure tone thresholds was achieved.</p><p><strong>Conclusion: </strong>Vestibulotomy and labyrinthotomy are safe and effective procedures in terms of hearing restoration, which can be applied in cases of congenital agenesis of the oval window or obstruction of the oval window by the facial nerve.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"320-4"},"PeriodicalIF":1.3,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000345714","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40217575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transoral robotic surgery with laser for head and neck cancers: a feasibility study.","authors":"Marco Benazzo,&nbsp;Pietro Canzi,&nbsp;Antonio Occhini","doi":"10.1159/000337092","DOIUrl":"https://doi.org/10.1159/000337092","url":null,"abstract":"<p><strong>Aims: </strong>To assess the feasibility of a flexible thulium laser coupled with a novel robotic introducer for head and neck cancers.</p><p><strong>Methods: </strong>In a prospective nonrandomized clinical trial, 58 patients were evaluated. When indicated, transoral robotic surgery (TORS) with laser was performed using an Intuitive da Vinci S System with the Intuitive Surgical® Endo Wrist Introducer, 5Fr to hold and position thulium surgical laser fibers.</p><p><strong>Results: </strong>Six patients underwent TORS with laser for early supraglottic and oropharyngeal squamous cell carcinomas. All approaches were successfully completed without the need for microscopic/open conversion or positive margins to the final pathological study. No intraoperative adverse events occurred and recovery was relatively quick, with no evidence of disease recurrence at the time of reporting, the short observation time notwithstanding.</p><p><strong>Conclusions: </strong>In our preliminary experience, TORS with laser showed feasible and promising results. Further studies are mandatory to demonstrate thulium laser benefits in surgical and oncological practice.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"124-8"},"PeriodicalIF":1.3,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000337092","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39970996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laser ablation of a large tongue hemangioma with remifentanil analgosedation in the ORL endoscopy suite.","authors":"Joshua H Atkins,&nbsp;Jeff E Mandel,&nbsp;Natasha Mirza","doi":"10.1159/000328341","DOIUrl":"https://doi.org/10.1159/000328341","url":null,"abstract":"<p><p>We present a unique, practical, and safe approach to the clinical management of a young male with a large tongue hemangioma who presented for serial surgical treatment of the lesion. Laser ablation was undertaken in the operating room under topical anesthesia with remifentanil analgosedation without the use of supplemental oxygen. Significant involution of the hemangioma was achieved without complication while the patient was awake, cooperative, and able to protect his airway. The application of remifentanil infusion for analgosedation during airway surgery is described. The utility of pharmacokinetic modeling in these applications is discussed along with the use of non-invasive respiratory inductance plethysmography to monitor ventilation during opioid sedation. The concept of analgosedation for airway surgery is introduced and relative risk versus benefit considerations of the approach in comparison to general anesthesia are discussed. This approach can be conceived of as an ORL endoscopy suite model for limited airway procedures.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"166-9"},"PeriodicalIF":1.3,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000328341","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40111440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression profile of p63 in 127 patients with laryngeal squamous cell carcinoma.","authors":"M Borba,&nbsp;C Cernea,&nbsp;F Dias,&nbsp;P Faria,&nbsp;C Bacchi,&nbsp;L Brandão,&nbsp;A Costa","doi":"10.1159/000319904","DOIUrl":"https://doi.org/10.1159/000319904","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate p63 expression in laryngeal squamous cell carcinoma and its prognostic significance.</p><p><strong>Methods: </strong>p63 expression was examined by immunohistochemistry and scored in 127 patients with laryngeal squamous cell carcinomas.</p><p><strong>Results: </strong>Sixty-two cases had scored 3, sixty had scored 2, four had scored 1 and one case did not show any expression (48.8, 47.2, 3.1 and 0.8%, respectively). Overall survival was 73.9% at 24 months and 59.5% at 60 months. The disease-free survival was 77.2 and 75.1%, and the disease-specific survival was 79 and 67% at 24 and 60 months, respectively. Uni- and multivariate analysis identified that decreased immunoexpression of protein p63 was a statistically significant factor for the risk of recurrence and death by cancer.</p><p><strong>Conclusions: </strong>p63 expression was highly prevalent in laryngeal squamous cell carcinomas, and its underexpression was correlated with a worse prognosis.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"319-24"},"PeriodicalIF":1.3,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000319904","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40074123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Speech perception with cochlear implants as measured using a roving-level adaptive test method.","authors":"Sabine Haumann,&nbsp;Thomas Lenarz,&nbsp;Andreas Büchner","doi":"10.1159/000318872","DOIUrl":"https://doi.org/10.1159/000318872","url":null,"abstract":"<p><strong>Aims: </strong>This paper uses a new method of speech testing where the hearing aid or cochlear implant (CI) users are tested in a more realistic listening situation.</p><p><strong>Methods: </strong>Groups of 11 subjects matched for performance with 5 different CI systems, for a total of 55 subjects, were tested with an adaptive test regime where the presentation level of the speech signal roved by ±10 or ±15 dB.</p><p><strong>Results: </strong>Speech reception thresholds varied widely between -4.8 and 17.3 dB with the ±15 dB roving condition being more difficult than the ±10 dB roving condition. We also found significant differences in speech reception threshold between groups using different devices.</p><p><strong>Conclusion: </strong>The test method used in our study, which attempts to test CI users in a more realistic listening situation, is sensitive to the effects of various subject-specific and technical parameters on everyday speech perception with CIs.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"312-8"},"PeriodicalIF":1.3,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000318872","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40074122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcutaneous cervical and transabdominal ultrasonography as a diagnostic tool in gastroesophageal reflux in childhood.","authors":"Bilge Karabulut,&nbsp;Ilknur Bostanci,&nbsp;Mahmut Kacar,&nbsp;Gokhan Karaca,&nbsp;Pinar Kosar","doi":"10.1159/000319900","DOIUrl":"https://doi.org/10.1159/000319900","url":null,"abstract":"<p><strong>Background/aim: </strong>The aim of this study is to investigate if there is a diagnostic expressive difference in the angle of His, upper and lower esophageal diameter (UED and LED), wall thickness of cervical esophagus (WTCE) measured by cervical and transabdominal ultrasonography (USG) between children with (+) and without gastroesophageal reflux (GER-).</p><p><strong>Methods: </strong>50 children were separated into 2 groups. Group 1 was the control group (n = 30) consisting of children who had no symptoms of GER and had no GER detected in USG. Group 2 was the study group (n = 20) consisting of children with complaints related to GER, and who were GER+ by USG and esophageal pH monitoring. The USG examinations were completed after having observed 3 episodes of reflux or after 30 min if no reflux was detected. The angle of His, UED, LED and WTCE were measured. In 24-hour esophageal pH monitoring, acid contact to the proximal or distal probe greater than 5.0% of the total time below pH 4 was accepted as pathologic reflux.</p><p><strong>Results: </strong>The age range of the 50 children (30 boys) was 4-13 years. Between the 2 groups there were no differences with regard to age and gender. Values of UED, LED and WTCE were statistically higher in group 2 compared with group 1. The angle of His was higher in the control group, but this was not statistically significant.</p><p><strong>Conclusion: </strong>Our study is the first in the literature that shows that measuring UED, LED and WTCE by USG, which is a noninvasive, readily available repeatable, cheap and fast technique, has a high diagnostic value in children with suspected GER.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"300-4"},"PeriodicalIF":1.3,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000319900","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40064581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of IL-17 and its role in bone destruction in human middle ear cholesteatoma.","authors":"Takuo Haruyama,&nbsp;Masayuki Furukawa,&nbsp;Takeshi Kusunoki,&nbsp;Junko Onoda,&nbsp;Katsuhisa Ikeda","doi":"10.1159/000319897","DOIUrl":"https://doi.org/10.1159/000319897","url":null,"abstract":"<p><strong>Purpose: </strong>The present study was designed to elucidate the immunoreactivity and protein level of IL-17 in human cholesteatomas.</p><p><strong>Procedures: </strong>The expression and localization of IL-17 and receptor activator of nuclear factor κB ligand (RANKL) were examined by immunohistochemistry in tissue specimens collected from 24 patients with cholesteatomas. The cellular sources of IL-17 were assessed by double staining with CD4. The level of IL-17 protein was determined using an enzyme-linked immunosorbent assay. The degree of bone destruction was compared with the IL-17 immunoreactivity.</p><p><strong>Results: </strong>IL-17 immunoreactivity was detected in the inflammatory cells in the granulation tissues and there were increased levels of IL-17 protein. The localization of IL-17 expression coincided with CD4-positive lymphocytes. IL-17 was correlated with the cells positive for RANKL. The degree of bone destruction was dependent on the number of infiltrated IL-17-positive cells. IL-17-driven pathology was observed in the congenital type as compared with the acquired type.</p><p><strong>Conclusions: </strong>The present study suggests that IL-17 is related to the pathogenesis of the disease.</p>","PeriodicalId":520736,"journal":{"name":"ORL; journal for oto-rhino-laryngology and its related specialties","volume":" ","pages":"325-31"},"PeriodicalIF":1.3,"publicationDate":"2010-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000319897","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40074124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}