Rahman Abdul, Abdul A Khoder, Angela Gong, Lazar Busija, Simon E Skalicky
{"title":"Online circular contrast perimetry: Tablet validation study against desktop test and standard automated perimetry.","authors":"Rahman Abdul, Abdul A Khoder, Angela Gong, Lazar Busija, Simon E Skalicky","doi":"10.1002/ovs2.70051","DOIUrl":"10.1002/ovs2.70051","url":null,"abstract":"<p><strong>Purpose: </strong>To assess correlation, agreement and diagnostic accuracy of a new tablet-based 24-degree, 52-point online circular contrast perimetry application (OCCP), compared to computer-based OCCP and standard automated perimetry (SAP).</p><p><strong>Methods: </strong>Seventy-five participants (26 controls, 49 glaucomatous) were tested via SAP using Humphrey field analyzer (Zeiss), then by computer OCCP on a 24-inch monitor, followed by two OCCP tests on a tablet (iPad Air 5th gen). Key outcome measures included pattern standard deviation (PSD), mean deviation (MD), mean sensitivity per point, and visual field index (VFI)/visual index (VI).</p><p><strong>Results: </strong>Agreement and correlation of VFI, PSD, and MD between OCCP tablet and SAP were very strong, with spearman's ρ and intra-class correlation coefficients between 0.81-0.86 and 0.80-0.93, respectively. MD Bland-Altman bias was greater for OCCP tablet against SAP-0.53 to 0.68 dB-compared to OCCP computer against SAP at 0.05 dB. 95% limits of agreement were comparable for OCCP versus SAP. Point-by-point Bland-Altman bias demonstrated tighter agreements between OCCP tablet and OCCP personal computer (PC) compared to OCCP generally and SAP. Receiver-operating-characteristic curves were comparable across outcomes between all OCCP tests, SAP, and cirrus optical coherence tomography parameters with no significant differences. Test duration was longer for OCCP tablet than SAP, whereas OCCP PC was shorter than SAP (p < 0.001).</p><p><strong>Conclusions: </strong>OCCP tablet has strong correlation, agreement, and similar area-under-curve in identifying glaucomatous eyes from controls to both SAP and OCCP computer, demonstrating prospect as a tool for glaucoma perimetry testing in low-resource settings, with further enhancements to reduce test duration.</p>","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 4","pages":"e70051"},"PeriodicalIF":1.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Guest editorial: Advances in Pediatrics and Binocular Vision Feature Issue.","authors":"Angela M Chen, Susan A Cotter","doi":"10.1002/ovs2.70061","DOIUrl":"https://doi.org/10.1002/ovs2.70061","url":null,"abstract":"","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 4","pages":"e70061"},"PeriodicalIF":1.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147985075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bethany E Higgins, David P Crabb, Pete R Jones, Stuart K Gardiner
{"title":"Location of visual field defects and their impact on vision-related quality of life in glaucoma: A systematic review.","authors":"Bethany E Higgins, David P Crabb, Pete R Jones, Stuart K Gardiner","doi":"10.1002/ovs2.70055","DOIUrl":"10.1002/ovs2.70055","url":null,"abstract":"<p><strong>Background: </strong>Regional patterns of visual field (VF) loss may affect vision-related quality of life (QoL) differently in people with glaucoma; yet evidence across studies remains inconsistent.</p><p><strong>Objectives: </strong>To identify and evaluate studies comparing vision-related QoL, measured by the National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), with specific regions of VF loss in glaucoma.</p><p><strong>Data sources: </strong>MEDLINE, EMBASE, CINAHL, PsycINFO, and AMED were systematically searched from inception to April 2025.</p><p><strong>Study eligibility criteria: </strong>Eligible studies included adults with glaucoma that examined regional VF loss (e.g., central vs. peripheral, hemifield, or cluster analyses) and reported NEI-VFQ-25 outcomes. Studies using only global VF indices were excluded.</p><p><strong>Study appraisal and synthesis methods: </strong>Two reviewers independently screened studies, extracted data, and assessed methodological quality using the Joanna Briggs Institute tools. Due to heterogeneity in VF metrics and NEI-VFQ-25 scoring approaches, the findings were synthesized narratively.</p><p><strong>Results: </strong>Nine studies (n = 2626 participants) met the inclusion criteria. Most cohorts were relatively young (mean age mid-60s) with mild-moderate glaucoma; only two included participants with advanced loss. Despite methodological variation, a consistent pattern emerged: central and inferior VF loss were most strongly associated with poorer QoL, whereas superior and peripheral loss showed weaker or domain-specific effects. Associations were generally stronger when using better-eye or integrated VF measures.</p><p><strong>Limitations: </strong>The evidence base is limited by few studies, small sample sizes, predominance of mild disease, and variability in both VF and NEI-VFQ-25 methodologies.</p><p><strong>Conclusions and implications of key findings: </strong>Central and inferior VF loss appear most closely linked to reduced QoL; however, conclusions are constrained by the limited number and methodological heterogeneity of available studies. Larger, standardized investigations across disease stages are needed to clarify these relationships and guide patient-centered care.</p><p><strong>Trial registration: </strong>PROSPERO CRD420251169334.</p>","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 4","pages":"e70055"},"PeriodicalIF":1.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147849255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Donald O Mutti, Loraine T Sinnott, Lisa A Jones-Jordan, David A Berntsen, Amber Gaume Giannoni, Danielle J Orr, Derik M Holmberg, Jeffrey J Walline
{"title":"Compensation for axial elongation during multifocal soft contact lens wear: Results from the BLINK study.","authors":"Donald O Mutti, Loraine T Sinnott, Lisa A Jones-Jordan, David A Berntsen, Amber Gaume Giannoni, Danielle J Orr, Derik M Holmberg, Jeffrey J Walline","doi":"10.1002/ovs2.70029","DOIUrl":"10.1002/ovs2.70029","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the effect of +2.50 D add multifocal soft contact lenses (MFSCLs) compared to +1.50 D add and single vision contact lenses (SVCLs) on the relationship between axial elongation and myopia progression.</p><p><strong>Methods: </strong>Individual estimates of D/mm were derived from the CLEERE Study, then applied to data from 289 participants in the BLINK Study to determine the portion of axial elongation that either contributed (uncompensated elongation) or did not contribute to myopia progression (compensated elongation). BLINK participants had myopia between -0.75 D and -5.00 D and were 7-11 years of age when enrolled in a 3-year clinical trial of multifocal contact lens myopia control. Cycloplegic refractive error was measured under tropicamide cycloplegia with the Grand Seiko WAM-5500 Binocular Autorefractor/Keratometer and axial length was measured using the Lenstar LS 900.</p><p><strong>Results: </strong>The majority of the inhibition of axial elongation during myopia control with +2.50 D add MFSCLs was inhibition of uncompensated elongation. Over 3 years, axial elongation was less in +2.50 D add MFSCLs (0.39 mm) compared to SVCLs (0.62 mm) by 0.23 mm (95% CI: 0.14, 0.33), split between 0.17 mm (95% CI: 0.091, 0.26) of uncompensated elongation and 0.055 mm (95% CI: 0.013, 0.097) of compensated elongation. Inhibition of compensated elongation only occurred in the first year of the study. Total axial elongation over 3 years would need to be reduced to 0.17 mm (0.45 mm less than 0.62 mm) to result in no myopia progression.</p><p><strong>Conclusions: </strong>Optical myopia control with multifocal contact lenses has a small but significant effect on the compensation for elongation from changes in the optical components of the eye. As a result, myopia control must set an aggressive therapeutic target if the goal is slowing axial elongation to the point of no net myopia progression.</p>","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 3","pages":"e70029"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marina Guro, Henrietta Wang, Jack Phu, Nimesh B Patel, Kaitlyn A Sapoznik, Hamza Shah, Michael Kalloniatis
{"title":"Case series: The value of fundus autofluorescence in inherited macular disease.","authors":"Marina Guro, Henrietta Wang, Jack Phu, Nimesh B Patel, Kaitlyn A Sapoznik, Hamza Shah, Michael Kalloniatis","doi":"10.1002/ovs2.70036","DOIUrl":"10.1002/ovs2.70036","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diagnostic utility of fundus autofluorescence (FAF) imaging in identifying and characterizing phenotypically classified inherited macular dystrophies. In this way, we aim to provide methods by which eye care practitioners can link FAF imaging and other clinical results or imaging modalities to aid their clinical decision-making.</p><p><strong>Case reports: </strong>Phenotypically identified inherited macular dystrophies, including Stargardt disease and related ABCA4 mutations, Best vitelliform dystrophy, pattern dystrophies, and cone and cone-rod dystrophies, are discussed.</p><p><strong>Conclusions: </strong>We provide evidence that the use of FAF alone and in combination with other clinical results and imaging modalities can assist in the diagnosis of a range of inherited macular dystrophies.</p>","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 3","pages":"e70036"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13267801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Using artificial intelligence in research and writing publications.","authors":"David B Elliott","doi":"10.1002/ovs2.70057","DOIUrl":"https://doi.org/10.1002/ovs2.70057","url":null,"abstract":"","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 3","pages":"e70057"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew Turpin, Vasanth Muthusamy, William H Morgan, Geoffrey Chan, Allison M McKendrick
{"title":"Small areas of damage due to glaucoma are less likely to be identified by SITA-Faster than SITA-Standard.","authors":"Andrew Turpin, Vasanth Muthusamy, William H Morgan, Geoffrey Chan, Allison M McKendrick","doi":"10.1002/ovs2.70032","DOIUrl":"10.1002/ovs2.70032","url":null,"abstract":"<p><strong>Purpose: </strong>To examine if clusters of colocated damaged locations repeatedly found during prior SITA-Standard (SS) visual field tests are not replicated in a subsequent SITA-Faster (SFR) test.</p><p><strong>Methods: </strong>Visual field series from the Lions Eye Institute, Perth, Australia were extracted if they had at least 4 SS fields followed by a SFR field and all fields had false positive rates and fixation losses less than 15%. Clusters of damaged locations were defined as either an isolated location with no damaged neighbors or a group of connected 24-2 points (not crossing the horizontal) that all had Pattern Deviation (PD) probability values below 1% of normal in all 3 SS tests immediately preceding the SFR test. For each cluster, the number of locations that were damaged in the SFR field that overlapped the established and repeatable SS clusters was computed and reported. We compare this proportion of overlap against the same calculations using the last SS as the final field. We also examine the effect of relaxing the PD criteria for damage in the final field on the proportion of overlap.</p><p><strong>Results: </strong>2519 eyes were included. For established, repeatable, and clusters of size 1, 2, 3, and 4 locations, the follow-up SFR field completely missed 46%, 26%, 11%, and 14% of the clusters whereas SS missed significantly less 26%, 11%, 4% and 1% (t-test with mixed paired and unpaired observations and p < 0.05). Relaxing the criteria for damage in the final field to PD < 5% reduced the miss rates for both methods, but SFR was still significantly worse than SS (SFR: 24%, 8%, 3%, and 6% vs. SS: 13%, 3%, 1%, and 1%).</p><p><strong>Conclusions: </strong>SITA-Faster tends to miss established clusters of damaged locations of size 4 or fewer locations in follow up visits at a higher rate than SITA-Standard.</p>","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 3","pages":"e70032"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Control of myopia progression by low-dose atropine (0.01%, 0.025% and 0.05%), defocus incorporated multiple segments/highly aspherical lenslets spectacles, and combined therapy in European children: A 3-year retrospective study.","authors":"Manon Grégoire, Léa Dormegny, David Gaucher, Lauriana Solecki, Tristan Bourcier, Arnaud Sauer","doi":"10.1002/ovs2.70007","DOIUrl":"10.1002/ovs2.70007","url":null,"abstract":"<p><strong>Purpose: </strong>Myopia control is crucial for pediatric eye care professionals. Although various treatments exist, their comparative efficacy, particularly in European populations, remains unclear. In real-life conditions, this study aimed to compare different strategies to slow myopia progression.</p><p><strong>Methods: </strong>This retrospective, nonrandomized study evaluated the efficacy of 0.01%, 0.025%, and 0.05% atropine, defocus incorporated multiple segments/highly aspherical lenslets (DIMS/HAL) spectacles, combined atropine and DIMS/HAL, and single vision spectacles in 288 European children (aged 5-12 years) with myopia progression (≥0.75 D in the past 12 months). Primary outcomes were changes in spherical equivalent refraction (SER) and axial length measured every 6 months for 3 years.</p><p><strong>Results: </strong>The mean cumulative 3-year SER progressions were -0.75 ± 0.49, -0.92 ± 0.52, and -1.31 ± 0.75 D for the 0.05%, 0.025%, and 0.01% atropine groups, respectively, -1.31 ± 0.76 D for the DIMS/HAL group, and -1.11 ± 0.65 D for the 0.01% atropine + DIMS/HAL group, showing better myopia progression control compared to those of the control group (-2.14 ± 0.72 D). Atropine exhibited a dose-dependent effect, with 0.05% atropine achieving the greatest reduction in myopia progression and axial elongation.</p><p><strong>Conclusions: </strong>This study demonstrates the efficacy of low-dose atropine and DIMS/HAL spectacles in slowing myopia progression in European children. The 0.05% atropine exhibited the most pronounced myopia control effect.</p>","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 3","pages":"e70007"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sondra M Rahmeh, Xinxing Guo, Medha Kallem, Megan E Collins
{"title":"Landscape analysis of school-based vision programs in the United States: A survey study.","authors":"Sondra M Rahmeh, Xinxing Guo, Medha Kallem, Megan E Collins","doi":"10.1002/ovs2.70039","DOIUrl":"10.1002/ovs2.70039","url":null,"abstract":"<p><strong>Purpose: </strong>Currently, there are neither guidelines for school-based vision program operations nor a registry of programs that exist in the United States. We aim to describe the characteristics of school-based vision programs across the United States through a survey.</p><p><strong>Methods: </strong>We identified 10 organizations that operated one or more school-based vision programs during the 2022-2023 school year. We developed and distributed an online survey form to collect information on program demographics, program components, and protocols for vision screenings and eye exams, as well as procedures for obtaining consent, dispensing glasses, and funding resources. Organizations were asked to complete a survey for each school district in which they operated, which we defined as an individual program. Programs that did not complete the survey were excluded. We used descriptive statistics to describe program characteristics. We compared grade levels that received vision screening by school-based vision programs and their respective screening mandate in the state where the programs operated.</p><p><strong>Results: </strong>Seven organizations participated and provided data about 184 unique school-based vision programs. These programs operated in 19 states and the District of Columbia. All 184 programs provided vision screenings, eye exams, and eyeglasses. 94.6% of programs included instrument-based screening, with 46.7% using it exclusively. School-based vision programs most frequently screened elementary school grades. For eye exams, 81% of programs utilized opt-out consent; 21.7% of programs included dilation. Vision screenings were mostly conducted by program staff (164/184, 89.1%), and eye exams were performed by optometrists (183/184, 99.5%). Nine programs (5.0%) reported providing additional care beyond eyeglasses provision, while 135 (73.4%) reported having an established relationship with community eye care providers for students referred for additional evaluation and care.</p><p><strong>Conclusions: </strong>Many school-based vision programs operate in the United States. These programs focus on vision screening, eye exams, and eyeglasses provision. Establishing a registry of programs would help to disseminate lessons learned and track outcomes data. Future programs will benefit from guidelines to ensure they are operating according to best practices.</p>","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 3","pages":"e70039"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Morgan C Ollinger, Marie I Bodack, Morgan I Bromley
{"title":"Peripheral retinal findings in a pediatric primary care optometry clinic and their associations with myopia: A 3-year retrospective review.","authors":"Morgan C Ollinger, Marie I Bodack, Morgan I Bromley","doi":"10.1002/ovs2.70006","DOIUrl":"10.1002/ovs2.70006","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to detail the frequency of peripheral retinal findings seen in pediatric patients in a primary care optometry clinic, and evaluate the relative frequency of abnormal and pathological peripheral retinal findings based on myopia magnitude.</p><p><strong>Methods: </strong>An observational retrospective cross-sectional study analyzed records for 874 patients aged 6-17 years who received routine eye exams at an academic eye care clinic in Memphis, TN between January 2020 and July 2023. Demographic data, refractive error, and peripheral retinal findings, both pathological and non-pathological, were evaluated. Overall frequencies of retinal findings were assessed, and further contrasted between levels of myopia.</p><p><strong>Results: </strong>Abnormal retinal findings were present in 177 participants (20.2%). Pathology was diagnosed in a total of 55 participants (6.3%). The frequency of abnormal peripheral retinal findings increased with myopia severity, with nearly half (44.8%) of patients with 3 or more diopters of myopia having at least one abnormal finding. Significant associations were found between myopia category and the presence of abnormal retinal findings (p < 0.0001), and between myopia category and retinal pathology (p < 0.0001), suggesting that children with 3 or more diopters of myopia have an elevated risk of peripheral retinal pathology detection compared to children with no myopia (odds ratio of 11.5, 95% CI: 4.8-27.8).</p><p><strong>Conclusions: </strong>These findings highlight the notable frequency of retinal findings in pediatric primary eye care patients. Peripheral retinal pathology is more common in pediatric patients with 3 or more diopters of spherical equivalent myopia, and present across all refractive error statuses. These results underscore the importance of a comprehensive dilated retinal evaluation in children, particularly those with myopia.</p>","PeriodicalId":520732,"journal":{"name":"Optometry and vision science : official publication of the American Academy of Optometry","volume":"103 3","pages":"e70006"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}