Neurosciences (Riyadh, Saudi Arabia)最新文献_第6页

Management options of chronic low back pain. A randomized blinded clinical trial. 慢性腰痛的治疗选择。一项随机盲法临床试验。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Mahmoud E Nazzal, Mohammed A Saadah, Loai M Saadah, Mahmoud A Al-Omari, Ziad A Al-Oudat, Mohammed S Nazzal, Mahfoud Y El-Beshari, Amani A Al-Zaabi, Yousif I Alnuaimi

{"title":"Management options of chronic low back pain. A randomized blinded clinical trial.","authors":"Mahmoud E Nazzal, Mohammed A Saadah, Loai M Saadah, Mahmoud A Al-Omari, Ziad A Al-Oudat, Mohammed S Nazzal, Mahfoud Y El-Beshari, Amani A Al-Zaabi, Yousif I Alnuaimi","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To compare efficacies of 2 active programs in the management of chronic low back pain (CLBP).Methods: This prospective, stratified, randomized single-blinded controlled study was conducted in the Department of Rehabilitation Medicine, King Abdullah University Hospital, Irbid, Jordan, between February and December 2010. A total of 100 patients were randomized to either 6-weeks of multidisciplinary rehabilitation (group A) or therapist-assisted exercise (group B). At baseline and 6 weeks, the visual analogue scale (VAS) pain score was estimated, as a primary outcome measure. McGill pain score, Oswestry Disability Index (ODI), trunk forward flexion and extension, left and right lateral bending, were applied before and after treatment and were employed as secondary outcome measures.Results: All outcome measures significantly improved in group A after treatment, compared with group B. The VAS, McGill, ODI scores, left and right lateral bending decreased significantly, whereas forward and backward bending increased. A significant number of patients returned to work in group A at the end of 6 weeks, compared with group B. These effects were maintained over 12 and 24 weeks of follow-up.Conclusion: Multidisciplinary rehabilitation improved functional indices and pain scale scores in group A compared with B. This would be an effective strategy in CLBP management.","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"152-9"},"PeriodicalIF":0.9,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40240556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generalized anhidrosis. 广义无汗症。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Serkan Yilmazer, Esra Okuyucu, Ismet Melek, Taskin Duman

引用次数: 0

Protective effect of coenzyme Q10 in paclitaxel-induced peripheral neuropathy in rats. 辅酶Q10对紫杉醇诱导大鼠周围神经病变的保护作用。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Nalan Celebi, Hemra Cil, Onur Cil, Ozgur Canbay, Rustu Onur, Ulku Aypar

{"title":"Protective effect of coenzyme Q10 in paclitaxel-induced peripheral neuropathy in rats.","authors":"Nalan Celebi, Hemra Cil, Onur Cil, Ozgur Canbay, Rustu Onur, Ulku Aypar","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the possible protective effect of coenzyme Q10 (CQ10) on neuropathy in rats.Methods: Experiments were conducted in the Department of Pharmacology, Faculty of Medicine, Hacettepe University, Ankara, Turkey between January and March 2012. Forty rats were divided into 4 groups: group 1 (control), group 2 (paclitaxel), group 3 (control + CQ10), and group 4 (paclitaxel + CQ10). Group 2 and 4 rats received paclitaxel (2 mg/kg, intraperitoneally, on days 0, 2, 4, 6). Group 3 and 4 rats were treated with CQ10 (10 mg/kg, intraperitoneally, on days 0, 1, 2, 3, 4, 5, 6, 7, 8, 9). The rats that did not receive paclitaxel or CQ10 received vehicle. Mechanical allodynia tests were performed for each animal on day 0, 2, 6, 8, 10, 14, 16, 19, 39 and 41 for all groups with von Frey filaments.Results: At day 0, mean mechanical withdrawal thresholds were similar among all groups. Starting from day 2, the threshold of the paclitaxel group decreased. Starting from day 10, paclitaxel+CQ10 treated rats had significantly higher thresholds compared with the paclitaxel group, but these values were still significantly lower than that of the controls. Control and control + CQ10 rats had similar threshold values during the protocol.Conclusion: The CQ10 treatment decreased the degree of paclitaxel-induced peripheral neuropathy in rats.","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"133-7"},"PeriodicalIF":0.9,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40240552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on serum zinc and selenium levels in epileptic patients. 癫痫患者血清锌、硒水平的研究。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Heidar N Farahani, Alireza R Ashthiani, Mher S Masihi

{"title":"Study on serum zinc and selenium levels in epileptic patients.","authors":"Heidar N Farahani, Alireza R Ashthiani, Mher S Masihi","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To estimate serum zinc and selenium levels in a group of healthy subjects and correlate these with epileptic patients.Methods: This case-control study was conducted in the Department of Neurology, Valiasr Hospital, Iran, between November 2011 and May 2012 on 40 patients aged 26.63+/-5.78 years who were diagnosed with generalized and a single epileptic form of epilepsy by a neurologist for the first time. The control group was selected from healthy individuals, and matched to the case group. Serum zinc was measured by the calorimetric method using a Randox kit. Selenium was measured by atomic absorption spectroscopy.Results: The mean zinc level was 151.2+/-29.75 ug/dl in the cases, and 181.63+/-60.19 ug/dl in the controls (p=0.006). The mean selenium level was 73.37+/-13.31 ug/l in cases compared with 85.55+/-19.39 ug/dl in controls (p=0.002). We also found a significant difference between the selenium levels by gender in the 2 groups (p=0.03).Conclusion: We observed statistically significant changes in serum zinc and selenium levels of epileptic adult patients in comparison with the control group. As zinc and selenium are used as potent antioxidants in cellular interactions, changes in their serum values may result in enzymatic changes, which in turn can cause neurological disorders.","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"138-42"},"PeriodicalIF":0.9,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40240553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiological predictors of neurological compromise in adults with filum terminale lipoma. 成人终丝脂肪瘤患者神经功能损害的影像学预测因素。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Amro F Al-Habib, Saad M Al-Rashidi, Fahad B Al-Badr, Hamdy H Hassan

引用次数: 0

Platelet alloantigen polymorphism and migraine headaches. 血小板异体抗原多态性与偏头痛。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Shalini Bhaskar, Jafri M Abdullah

引用次数: 0

Hypertensive encephalopathy as the initial manifestation of Guillain-Barré syndrome in a 7-year-old girl. 高血压脑病作为格林-巴-罗综合征的最初表现在一个7岁的女孩。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Ayman A Aleyadhy, Gamal M Hassan

引用次数: 0

Co-morbid Guillain-Barré syndrome and acute disseminated encephalomyelitis. 格林-巴<s:1>综合征和急性播散性脑脊髓炎共病。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Reema R Mohammed, Mohammed M Jan

引用次数: 0

Role of 17-beta estradiol in baroreflex sensitivity in the nucleus tractus solitarii via the autonomic system in ovariectomized rats. 17- β雌二醇在去卵巢大鼠孤束核自主神经反射敏感性中的作用。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Aliasghar Pourshanazari, John Ciriello, Haleh Tajadini

{"title":"Role of 17-beta estradiol in baroreflex sensitivity in the nucleus tractus solitarii via the autonomic system in ovariectomized rats.","authors":"Aliasghar Pourshanazari, John Ciriello, Haleh Tajadini","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the effect of estrogen exerted through the autonomic system in the nucleus tractus solitarii (NTS) on increasing the sensitivity of the baroreflex under conditions of acute hypertension in ovariectomized rats.Methods: In this experimental study, conducted in Kerman University of Medical Sciences, Kerman, Iran from March 2010 to October 2010, 36 female rats were ovariectomized and then estrogen capsules were implanted beneath their skin. After 2 weeks, the left femoral vein and artery were cannulated for phenylephrine infusion and recording of mean arterial pressure and heart rate. Subsequently, atropine, propranolol, and saline were injected into the NTS, followed by measurements of changes in heart rate and changes in mean arterial pressure just prior to phenylephrine infusion.Results: Estrogen increased the bradycardia response and inhibited the rise of mean arterial pressure; namely, after phenylephrine infusion, the change in heart rate was significantly lower in the estrogen-receiving group compared with the control group (p<0.05). Baroreflex sensitivity was significantly increased in the estrogen-receiving group compared with the control group (p<0.01). Baroreflex sensitivity was significantly attenuated in both groups (estrogen-receiving and control) after atropine injection, compared with after propranolol or saline injection (p<0.01).Conclusion: It is probable that under conditions of acute hypertension, estrogen affects the NTS through the parasympathetic system and enhances baroreflex sensitivity.","PeriodicalId":520723,"journal":{"name":"Neurosciences (Riyadh, Saudi Arabia)","volume":" ","pages":"126-32"},"PeriodicalIF":0.9,"publicationDate":"2013-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40240551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary antiphospholipid syndrome manifesting as partial status epilepticus. 原发性抗磷脂综合征表现为部分癫痫持续状态。

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Neurosciences (Riyadh, Saudi Arabia) Pub Date : 2013-04-01

Nancy N Maalouf, Archana Hinduja, Bashir S Shihabuddin

引用次数: 0