Hormones (Athens, Greece)最新文献

{"title":"Artificial intelligence vs human opportunistic detection of vertebral fractures in routine CT scans: results of a pilot study.","authors":"Polyzois Makras, Eleftherios Chatzellis, Christos Gravvanis, Georgia Kanti, Maria P Yavropoulou, Konstantinos Papadimitropoulos, Nikolaos Kyriakopoulos","doi":"10.1007/s42000-026-00784-1","DOIUrl":"https://doi.org/10.1007/s42000-026-00784-1","url":null,"abstract":"","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The predictive health index: a turning point in the transition from disease medicine to preventive medicine.","authors":"Georgios Valsamakis","doi":"10.1007/s42000-026-00778-z","DOIUrl":"https://doi.org/10.1007/s42000-026-00778-z","url":null,"abstract":"","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147701893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gonadal recovery in men with prolactinomas on cabergoline: 6-month testosterone levels as a predictor of testosterone replacement timing.","authors":"Neslihan Koray Fedai, Nagihan Uzun, Hayri Bostan, Muhammed Kizilgul, Taner Demirci, Erman Cakal, Bekir Ucan","doi":"10.1007/s42000-026-00766-3","DOIUrl":"https://doi.org/10.1007/s42000-026-00766-3","url":null,"abstract":"<p><strong>Purpose: </strong>Hypogonadotropic hypogonadism is a frequent manifestation of prolactinomas in men. Dopamine agonists can restore gonadal function; however, the timeline and predictors of recovery are not well defined. This study focuses on hypogonadotropic hypogonadism exclusively among men with prolactinomas.</p><p><strong>Methods: </strong>We retrospectively analyzed 84 men with prolactinomas treated with cabergoline (CAB) for at least 12 months, without prior pituitary surgery or radiotherapy. Hypogonadotropic hypogonadism was defined as morning testosterone < 300 ng/dL with low or inappropriately normal luteinizing hormone (LH). Recovery was defined as testosterone ≥ 300 ng/dL.</p><p><strong>Results: </strong>At baseline, 75 patients (89.3%) had hypogonadotropic hypogonadism. Gonadal recovery was observed in 30.7% at 6 months, 44% at 12 months, and 59.5% at 24 months. Mean testosterone increased from 142 ng/dL at baseline to 352.5 ng/dL at 24 months, with continued improvement between 12 and 24 months (p < 0.001). Independent predictors of recovery at 12 months were smaller baseline tumor diameter (OR = 0.934, 95%CI: 0.894-0.977, p = 0.003) and higher baseline testosterone (OR = 1.009, 95%CI: 1.000-1.018, p = 0.042). When 6-month parameters were included, only testosterone at 6 months remained predictive (OR = 1.030, 95%CI: 1.014-1.047, p < 0.001). Optimal cut-offs for persistent hypogonadism at 12 months were tumor diameter > 2.3 cm (sensitivity 64.3%, specificity 63.6%), baseline testosterone < 144.5 ng/dL (sensitivity 63.6%, specificity 61.9%), and 6-month testosterone < 234.0 ng/dL (sensitivity 87.9%, specificity 88.1%).</p><p><strong>Conclusion: </strong>Gonadal function recovers in a substantial proportion of men with prolactinomas during CAB therapy, often within the first year. Six-month testosterone levels, along with baseline tumor size, are strong predictors of recovery and may help guide testosterone replacement timing.</p>","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147597657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An overview of the role of platelets in vascular disease associated with diabetes mellitus.","authors":"Theodoros Panou, Djordje S Popovic, Dimitri P Mikhailidis, Nikolaos Papanas","doi":"10.1007/s42000-026-00760-9","DOIUrl":"https://doi.org/10.1007/s42000-026-00760-9","url":null,"abstract":"","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147597561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibrous dysplasia in a patient with Carney complex.","authors":"Maria Ponte, Vítor Carneiro, Andreia Pataco, Regina Medeiros, Constantine A Stratakis, João Anselmo","doi":"10.1007/s42000-026-00771-6","DOIUrl":"https://doi.org/10.1007/s42000-026-00771-6","url":null,"abstract":"","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147597643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiofrequency ablation as an alternative treatment for hyperparathyroidism: a case study of a single parathyroid adenoma and review of the literature.","authors":"Maria Chrysoula Tatarida Palla, Aspasia Drosou, Pyrros Gkousis, Anna Drakopoulou, Styliani Kalaitzidou, Eirini Veniou, Myrsini Gkeli","doi":"10.1007/s42000-026-00772-5","DOIUrl":"https://doi.org/10.1007/s42000-026-00772-5","url":null,"abstract":"","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147523863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal trends and demographic and regional disparities in adrenocortical insufficiency-related mortality in the United States from 1999 to 2020.","authors":"Ahmed Faizan, Zain Shahzad, Muhammad Sarosh Tahir, Rabail Abdul Qadir, Eeshal Fatima","doi":"10.1007/s42000-026-00768-1","DOIUrl":"https://doi.org/10.1007/s42000-026-00768-1","url":null,"abstract":"","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147523874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current management of MASLD in type 2 diabetes.","authors":"Valeria Michelle Fernández-Garibay, Vianney Sarabia-Chao, Norberto C Chavez-Tapia","doi":"10.1007/s42000-026-00763-6","DOIUrl":"https://doi.org/10.1007/s42000-026-00763-6","url":null,"abstract":"","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147523830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision medicine in thyroid nodules: current strategies, challenges, and future directions.","authors":"Marcio J Concepción-Zavaleta, Jenyfer M Fuentes-Mendoza, Cristian A Rojas-Hipólito, Daniela Sánchez-Mejía, Mariana A López-Torres, Luis Concepción-Urteaga, Cristian D Armas, José Paz-Ibarra","doi":"10.1007/s42000-026-00757-4","DOIUrl":"https://doi.org/10.1007/s42000-026-00757-4","url":null,"abstract":"","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147523845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"miR-613 regulates osteogenic differentiation by targeting TIMP3 in postmenopausal osteoporosis.","authors":"Yuan Ruan, Sicheng Ding, Yingxuan Huang, Ningning Zhang","doi":"10.1007/s42000-026-00770-7","DOIUrl":"https://doi.org/10.1007/s42000-026-00770-7","url":null,"abstract":"","PeriodicalId":520640,"journal":{"name":"Hormones (Athens, Greece)","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147523836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}