Diabetes & metabolic syndrome最新文献_第8页

Higher levels of thioredoxin interacting protein (TXNIP) in patients with prediabetes compared to obese normoglycemic subjects. 糖尿病前期患者的硫氧还蛋白相互作用蛋白(TXNIP)水平高于肥胖正常血糖受试者。

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-11-30 DOI: 10.1016/j.dsx.2018.11.056

Antoaneta T Gateva, Yavor S Assyov, Tsvetelina Velikova, Zdravko A Kamenov

{"title":"Higher levels of thioredoxin interacting protein (TXNIP) in patients with prediabetes compared to obese normoglycemic subjects.","authors":"Antoaneta T Gateva, Yavor S Assyov, Tsvetelina Velikova, Zdravko A Kamenov","doi":"10.1016/j.dsx.2018.11.056","DOIUrl":"https://doi.org/10.1016/j.dsx.2018.11.056","url":null,"abstract":"Background: Thioredoxin interacting protein (TXNIP) is one of the mediators of oxidative stress induced beta-cell glucotoxisity. TXNIP might play a key role in impaired glucose homeostasis preceding overt T2DM. The aim of the present study was to compare TXNIP levels between patients with prediabetes and obese normoglycemic controls and to evaluate the link between TXNIP and metabolic risk factors.Patients and methods: In the present study we included 79 patients with mean age 50.3 ± 10.6 years, divided into two age and BMI matched groups -control group with obesity without glycemic disturbances (NGT) (n = 40) and prediabetes (n = 39).Results: We found significantly higher levels of TXNIP in patients with prediabetes compared to normoglycemic obese controls (54.2 ± 69.9 vs. 23.9 ± 47.1 pg/ml; p = 0.03). The levels of TXNIP gradually increased from normal glucose tolerance trough IFG/IGT only to IFG + IGT (27,1; 44.0; 49.9 and 95.7 pg/ml respectively; p = 0.025 between NGT and IFG + IGT). TXNIP levels correlated weakly only with fasting blood glucose (r = 0.235; p = 0.04) but not with glucose during OGTT or the markers of insulin resistance.Conclusions: The levels of TXNIP are higher in patients with prediabetes compared to normoglycemic controls as they increase gradually from NGT trough IFG/IGT only to IFG + IGT.","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"734-737"},"PeriodicalIF":10.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2018.11.056","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36861906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

The morphofunctional features of platelets against the background of metabolic syndrome in patients with generalized marginal periodontitis. 广泛性周周炎患者代谢综合征背景下血小板形态功能特征。

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-12-03 DOI: 10.1016/j.dsx.2018.11.057

Yu L Vasil'ev, O V Kytko, N S Smetneva, I V Goloborodova, M V Nelipa

{"title":"The morphofunctional features of platelets against the background of metabolic syndrome in patients with generalized marginal periodontitis.","authors":"Yu L Vasil'ev, O V Kytko, N S Smetneva, I V Goloborodova, M V Nelipa","doi":"10.1016/j.dsx.2018.11.057","DOIUrl":"https://doi.org/10.1016/j.dsx.2018.11.057","url":null,"abstract":"According to modern ideas, disorders in the system of hemostasis in cardiovascular diseases are mainly due to an increase in the functional activity of platelets, namely their increased ability to adhere and aggregate. Aim of the research was to evaluate morphofunctional platelets of patients with marginal periodontitis. Material and methods of the study involved 129 men aged 28-50 years (mean age 42.97 ± 1.31 years) suffering from a MS with generalized periodontitis of mild and moderate degree. We also formed a control group of 90 practically healthy men (mean age 42.17 ± 1.34 years). Exclusion criteria are symptomatic AH, unstable angina, myocardial infarction or stroke in history, severe chronic heart failure, severe liver and kidney disease, diabetes, complete secondary adentia. Patients were performed the dental examination with determination of community periodontal index of treatment needs (CPITN), X-ray examination, physical examination with determination of anthropometric data, as well as clinical, the definition of MS laboratory criteria, insulin resistance indices, 24-h blood pressure monitoring. Platelet morphology was studied using scanning electron [17 clauser] microscopy (PhilipsPSEM 550 h) on samples prepared by a special method. The results of the study of platelet morphology in patients with MS and control group revealed a non-uniform pattern. The number of platelets in both groups being almost equal (249,6 ± 8,3х109/l and 256,8 ± 8,7х109/l respectively). Conclusion: The presented data provide strong evidence for changes in the morphofunctional state of peripheral blood platelets in patients with generalized marginal periodontitis of mild and moderate degree against the background of metabolic syndrome.","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"730-733"},"PeriodicalIF":10.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2018.11.057","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36862329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Metabolic syndrome components and prostatic hyperplasia among diabetic and non-diabetic men in the Eastern DR Congo: A cross-sectional study. 刚果民主共和国东部糖尿病和非糖尿病男性的代谢综合征成分和前列腺增生:一项横断面研究。

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-12-05 DOI: 10.1016/j.dsx.2018.11.064

L E Mubenga, D Gruson, M P Hermans, E Bwenge, B Tombal

引用次数: 1

The prevalence of macro and microvascular complications of DM among patients in Ethiopia 1990-2017: Systematic review. 1990-2017年埃塞俄比亚糖尿病患者大血管和微血管并发症患病率:系统回顾

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-11-14 DOI: 10.1016/j.dsx.2018.11.046

Bayu Begashaw Bekele

{"title":"The prevalence of macro and microvascular complications of DM among patients in Ethiopia 1990-2017: Systematic review.","authors":"Bayu Begashaw Bekele","doi":"10.1016/j.dsx.2018.11.046","DOIUrl":"https://doi.org/10.1016/j.dsx.2018.11.046","url":null,"abstract":"Background: The prevalence of diabetes mellitus (DM) has been growing rapidly in the world. It is smashing particularly the lower and middle income countries (LMICs) severely. Due to its acute and chronic complications many lives have fallen under its bad shadow. Therefore, we aimed to review the existing evidence on major types and specific complications of DM among diabetic patients in Ethiopia.Methods: Both relevant quantitative and qualitative studies, conducted after 1990s, investigated and reported DM and complications from MEDLINE/PubMed, CINAHL, SCOPUS, DAOJ and Cochrane library databases were explored. In addition, System for Information for grey literature in Europe (SINGLE) database was investigated for the existence of unpublished grey literature. Total of 161 titles were identified and 17 studies met the inclusion criteria. Findings were narrated descriptively.Results: In this review 17 studies were included, and both macro and micro complications were summarized. Among the diabetic complications retinopathy, nephropathy, metabolic syndrome, impotence and depression were the main findings among diabetic patients in Ethiopia.Conclusion: The burden of DM and its microvascular and macrovascular complications have been increasing among diabetic patients in Ethiopia. The increased duration of the diseases, lower socio economic level, existence of other complications, old age attributed the diabetic complications. Therefore, close monitoring and follow up of diabetic patients is necessary to reduce the incidence and prevalence of diabetic complications among the patients.","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"672-677"},"PeriodicalIF":10.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2018.11.046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36906455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Altered levels of sirtuin genes (SIRT1, SIRT2, SIRT3 and SIRT6) and their target genes in adipose tissue from individual with obesity. 肥胖个体脂肪组织中sirtuin基因(SIRT1、SIRT2、SIRT3和SIRT6)及其靶基因水平的改变

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-11-10 DOI: 10.1016/j.dsx.2018.11.011

Verónica Martínez-Jiménez, Nancy Cortez-Espinosa, Eduardo Rodríguez-Varela, Mariela Vega-Cárdenas, Margarita Briones-Espinoza, Víctor M Ruíz-Rodríguez, Nallely López-López, Armando Briseño-Medina, Eneida Turiján-Espinoza, Diana P Portales-Pérez

{"title":"Altered levels of sirtuin genes (SIRT1, SIRT2, SIRT3 and SIRT6) and their target genes in adipose tissue from individual with obesity.","authors":"Verónica Martínez-Jiménez, Nancy Cortez-Espinosa, Eduardo Rodríguez-Varela, Mariela Vega-Cárdenas, Margarita Briones-Espinoza, Víctor M Ruíz-Rodríguez, Nallely López-López, Armando Briseño-Medina, Eneida Turiján-Espinoza, Diana P Portales-Pérez","doi":"10.1016/j.dsx.2018.11.011","DOIUrl":"https://doi.org/10.1016/j.dsx.2018.11.011","url":null,"abstract":"Introduction: Sirtuins regulate energy metabolism and insulin sensitivity through their ability to act as energy sensors and regulators in several metabolic tissues.Aim: To evaluate the expression levels of sirtuin genes SIRT1, SIRT2, SIRT3 and SIRT6 and their target genes (PPAR-α, PGC1-α, NRF1, DGAT1, PPAR-γ and FOXO3a) in subcutaneous adipose tissue collected from individuals with normoweight, overweight and obesity.Methods: Adipose tissue samples, obtained by lipoaspiration during liposuction surgery, were processed to obtain RNA, which was reverse-transcribed to cDNA. Then, we measured the expression levels of each gene by qPCR.Results: We found differences in the mRNA expression of SIRT1, SIRT2, SIRT3 and SIRT6 and their target genes (PPAR-α, PGC1-α, NRF1, DGAT1, PPAR-γ and FOXO3a) in adipose tissue from overweight or obese subjects when compared to normoweight subjects. All genes analyzed, except SIRT2, showed correlation with BMI.Conclusions: Our findings in human subcutaneous adipose tissue show that increased body mass index modifies the expression of genes encoding sirtuins and their target genes, which are metabolic regulators of adipose tissue. Therefore, these could be used as biomarkers to predict the ability of adipose tissue to gain mass of adipose tissue.","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"582-589"},"PeriodicalIF":10.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2018.11.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36852511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Resolvin D1 impacts on insulin resistance in women with polycystic ovary syndrome and healthy women. Resolvin D1对多囊卵巢综合征女性和健康女性胰岛素抵抗的影响

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-11-15 DOI: 10.1016/j.dsx.2018.11.018

Nava Morshedzadeh, Ahmad Saedisomeolia, Mahmoud Djalali, Mohammad Reza Eshraghian, Sedigheh Hantoushzadeh, Maryam Mahmoudi

{"title":"Resolvin D1 impacts on insulin resistance in women with polycystic ovary syndrome and healthy women.","authors":"Nava Morshedzadeh, Ahmad Saedisomeolia, Mahmoud Djalali, Mohammad Reza Eshraghian, Sedigheh Hantoushzadeh, Maryam Mahmoudi","doi":"10.1016/j.dsx.2018.11.018","DOIUrl":"https://doi.org/10.1016/j.dsx.2018.11.018","url":null,"abstract":"Aims: The aim of this study was to determine the association between the intake of omega-3 PUFAs and the serum level of resolvin D1 and insulin resistance in women with Polycystic Ovary Syndrome (PCOS) compared to healthy women.Methods: A cross-sectional study was conducted in 2015-2016 in Tehran, Iran, among females referred to the infertility clinic at Valie-Asr Reproductive Health Research Centre. Thirty-one patients with PCOS (according to the criteria of the European Society for Human Reproduction and Embryology (ESHRE) and the American Society for Reproductive Medicine (ASRM)) and 29 healthy, normal cycling (NC) women of similar age, weight and height were enrolled. Anthropometric measurements, levels of resolvin D1, fasting insulin, glucose levels and insulin resistance index (HOMA) for each of the patients were determined.Results: Intakes of macronutrients (protein, carbohydrates, and total fat) and omega-3 PUFAs were higher in the PCOS group compared to the control group; also, the PCOS group had significantly higher resolvin D1, fasting insulin, glucose levels and HOMA when compared with the control group. Moreover, resolvin D1 correlated negatively with HOMA and fasting insulin levels among both the PCOS and control women.Conclusion: PCOS is associated with insulin resistance. We showed that omega-3 PUFAs can increase the synthesis of resolvin D1. Resolvin D1 is involved in insulin sensitivity by affecting insulin signaling and inflammatory pathways. Therefore, it can be a contributing factor in reducing insulin resistance in PCOS patients.","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"660-664"},"PeriodicalIF":10.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2018.11.018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36905961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Nephrotic range proteinuria; does it predict lung involvement in patients with type 2 diabetes. 肾病范围蛋白尿;它能预测2型糖尿病患者肺部病变吗?

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-11-15 DOI: 10.1016/j.dsx.2018.11.031

Omar Farooq Nafea Al-Azzawi, Mohammed Waheeb Alobaidy, Momtaz M Saham

{"title":"Nephrotic range proteinuria; does it predict lung involvement in patients with type 2 diabetes.","authors":"Omar Farooq Nafea Al-Azzawi, Mohammed Waheeb Alobaidy, Momtaz M Saham","doi":"10.1016/j.dsx.2018.11.031","DOIUrl":"https://doi.org/10.1016/j.dsx.2018.11.031","url":null,"abstract":"Background: Diabetes mellitus is a chronic metabolic disorder that is well known for its long term serious complications. Proteinuria whether micro or macroproteinuria is one of these complications. Many studies has related proteinuria to other complications of diabetes as retinopathy and cardiovascular disease of diabetes, while the lungs of diabetic patients which is the largest organ in the body with a large macro and microvascular bed, has not been related to this complication.Aim: The aim of the study was to find out whether proteinuria in diabetic patients can predict lung involvement.Patients and methods: A comparative cross sectional study in which we compared the lung function of 100 type 2 diabetic patients with proteinuria with that of 100 type 2 diabetic patients without proteinuria. Proteinuria is measured in a random sample by \"urine protein/urine creatinine ratio\". FEV1 and FVC were measured by spirometer.Results: The results showed that patients with proteinuria had a high frequency of abnormal PFT (86%), while patients without proteinuria had a low frequency of abnormal PFT (11%).Also diabetic patients with proteinuria had lower FVC (72.9 ± 6.5 vs. 88.2 ± 8.2), than diabetic patients without proteinuria.Conclusions: We concluded that diabetes mellitus causes a significant impairment in pulmonary function test. This impairment is significantly related with proteinuria.","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"622-625"},"PeriodicalIF":10.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2018.11.031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36851934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Hypertriglyceridaemic waist is associated with hyperuricaemia and metabolic syndrome in rheumatoid arthritis patients. 高甘油三酯血症腰与类风湿关节炎患者的高尿酸血症和代谢综合征相关。

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-12-01 DOI: 10.1016/j.dsx.2018.11.053

Oscar Zaragoza-García, José Eduardo Navarro-Zarza, Joyarib Y Maldonado-Anicacio, Natividad Castro-Alarcón, Isela Parra Rojas, Iris Paola Guzmán-Guzmán

{"title":"Hypertriglyceridaemic waist is associated with hyperuricaemia and metabolic syndrome in rheumatoid arthritis patients.","authors":"Oscar Zaragoza-García, José Eduardo Navarro-Zarza, Joyarib Y Maldonado-Anicacio, Natividad Castro-Alarcón, Isela Parra Rojas, Iris Paola Guzmán-Guzmán","doi":"10.1016/j.dsx.2018.11.053","DOIUrl":"https://doi.org/10.1016/j.dsx.2018.11.053","url":null,"abstract":"Background: /Aim: The hypertriglyceridaemic waist (HTGW) phenotype has been described and suggested in general population as a cardiovascular risk marker. The aim of the present study was to evaluate the HTGW phenotype as a marker related to HUC and MetS in rheumatoid arthritis (RA).Materials and methods: This was a cross-sectional study was designed in 250 RA Mexicans patients. The HTGW phenotype was defined as elevated waist circumference and elevated triglyceride concentration. Logistic regression analysis was used to evaluate the association between the HTGW phenotype, HUC and MetS in its traditional NCEP/ATPIII versions and modified (HTGWm and MetSm).Results: The prevalence of HTGW and HTGWm it was 20.4% and 32%, respectively. All patients with HTGW presented MetS (P < 0.001), and in a multivariate model, the HTGW phenotype was the marker most closely related to HUC in comparison to components of MetS.Conclusion: The HTGW may represent a marker for screening of cardiometabolic risk in RA patients, so in clinical practice can be implemented as a low-cost marker in the evaluation of the patient regardless of clinical characteristics of disease.","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"722-729"},"PeriodicalIF":10.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2018.11.053","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36861904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

The association between serum irisin levels and cardiovascular disease in diabetic patients. 糖尿病患者血清鸢尾素水平与心血管疾病的关系

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-11-30 DOI: 10.1016/j.dsx.2018.11.050

Zahra Mazloum Khorasani, Ramin Khameneh Bagheri, Mohammad Ali Yaghoubi, Saeed Chobkar, Monavvar Afzal Aghaee, Mohammad Reza Abbaszadegan, Amirhossein Sahebkar

{"title":"The association between serum irisin levels and cardiovascular disease in diabetic patients.","authors":"Zahra Mazloum Khorasani, Ramin Khameneh Bagheri, Mohammad Ali Yaghoubi, Saeed Chobkar, Monavvar Afzal Aghaee, Mohammad Reza Abbaszadegan, Amirhossein Sahebkar","doi":"10.1016/j.dsx.2018.11.050","DOIUrl":"https://doi.org/10.1016/j.dsx.2018.11.050","url":null,"abstract":"Background: Cardiovascular disease is the most common cause of mortality and morbidity in diabetic patients. Insulin resistance has been shown to be reduced by the secretion of irisin from muscle and adipose tissues. This study was aimed at determining the relationship between serum irisin levels and angiographically defined coronary artery disease (CAD) in type II diabetic patients.Methods: In this case-control study, 30 diabetic subjects with angiographically defined CAD were compared with 30 age- and sex-matched diabetic subjects without CAD in terms of clinical and laboratory parameters including serum irisin levels.Results: Serum levels of Irisin were significantly higher in the diabetic group without CAD compared with the group with CAD (P = 0.048). Serum irisin levels showed a significant positive correlation with BMI (r = 0.374, P = 0.004) and fasting insulin (r = 0.303, P = 0.021), and a significant negative correlation with diabetes duration (r = -0.384, P = 0.002). Based on the results of the binary logistic regression model, circulating levels of irisin were associated with the presence of CAD in diabetes (p = 0.038) after adjusting for potential confounders.Conclusion: Serum irisin levels were lower in the diabetic patients with cardiovascular complication compared with the uncomplicated diabetic patients. Therefore, additional larger scale studies are needed to determine the role of irisin in monitoring CAD in diabetic patients.","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"786-790"},"PeriodicalIF":10.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2018.11.050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36863091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 26

Association Between dietary patterns and the risk of metabolic syndrome among Iranian population: A cross-sectional study. 饮食模式与伊朗人群代谢综合征风险之间的关系:一项横断面研究。

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Diabetes & metabolic syndrome Pub Date : 2019-01-01 Epub Date: 2018-12-01 DOI: 10.1016/j.dsx.2018.11.059

Zahra Asadi, Mojtaba Shafiee, Fatemeh Sadabadi, Maryam Saberi-Karimian, Susan Darroudi, Maryam Tayefi, Hamideh Ghazizadeh, Alireza Heidari Bakavoli, Mohsen Moohebati, Habibollah Esmaeily, Gordon A Ferns, Majid Ghayour-Mobarhan

{"title":"Association Between dietary patterns and the risk of metabolic syndrome among Iranian population: A cross-sectional study.","authors":"Zahra Asadi, Mojtaba Shafiee, Fatemeh Sadabadi, Maryam Saberi-Karimian, Susan Darroudi, Maryam Tayefi, Hamideh Ghazizadeh, Alireza Heidari Bakavoli, Mohsen Moohebati, Habibollah Esmaeily, Gordon A Ferns, Majid Ghayour-Mobarhan","doi":"10.1016/j.dsx.2018.11.059","DOIUrl":"https://doi.org/10.1016/j.dsx.2018.11.059","url":null,"abstract":"Background: The role of dietary patterns in metabolic syndrome has not been investigated sufficiently among Iranian population. The aim of this study is to investigate the association of major dietary patterns with the risk of metabolic syndrome and its components among healthy individuals of Iran.Methods: This is a cross-sectional study that was performed on 5895 men and women who participated in MASHAD study project. Factor analysis was employed to determine major dietary patterns with regard to a validated 65-item food frequency questionnaire. Metabolic syndrome was diagnosed using international diabetes federation (IDF). Logistic regression analysis was used to evaluate the association between dietary patterns and metabolic syndrome risk to generate odds ratios (ORs) and 95% confidence intervals (CI).Results: Three major dietary patterns (Balanced, Western and high carbohydrate) were identified. The Western pattern showed a positive association with metabolic syndrome (OR [95%CI] for highest vs. lowest tertile: 1.58 [1.21-2.06]; p value = 0.001). The high carbohydrate dietary pattern was associated with higher metabolic syndrome risk (OR [95%CI] for highest vs. lowest tertile: 1.17 [1.02-1.33]; P value = 0.022). The Balanced dietary pattern was unrelated to metabolic syndrome, but was related to some individual risk factors for metabolic syndrome.Conclusions: These results suggest that the Western and high carbohydrate patterns are associated with an increased risk for metabolic syndrome among Iranian adults. The causality of these associations needs to be confirmed.","PeriodicalId":520602,"journal":{"name":"Diabetes & metabolic syndrome","volume":" ","pages":"858-865"},"PeriodicalIF":10.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dsx.2018.11.059","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36852519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12