Abdominal radiology (New York)最新文献

{"title":"Diversity in abdominal radiology: a decade-long review of gender, racial, and ethnic representation among fellows.","authors":"Abdullah Jalal, Emily Jagenburg, Kiran R Nandalur, Sayf Al-Katib","doi":"10.1007/s00261-026-05789-3","DOIUrl":"https://doi.org/10.1007/s00261-026-05789-3","url":null,"abstract":"<p><strong>Purpose: </strong>Recent analyses have characterized demographic trends in neuroradiology fellowships; however, diversity patterns within abdominal radiology fellowships have not been independently evaluated. This study examines gender and racial/ethnic representation among abdominal radiology fellows over a decade and contextualizes these findings relative to published neuroradiology fellowship data and broader radiology workforce trends.</p><p><strong>Methods: </strong>Publicly available Accreditation Council for Graduate Medical Education (ACGME) Data Resource Book data were analyzed for abdominal radiology fellows from academic years 2014-2015 through 2023-2024. Self-reported gender and race/ethnicity were extracted. Underrepresented in medicine (URM) status was defined as Hispanic/Latino, Black/African American, American Indian/Alaskan Native, and Native Hawaiian/Pacific Islander. Binomial logistic regression and Cochran-Armitage trend testing were performed to assess temporal trends.</p><p><strong>Results: </strong>A total of 468 abdominal radiology fellows were identified across 10 academic years, with 44-54 fellows enrolled annually. Overall, 29.9% were female and 6.6% met URM criteria. Female representation ranged from 17.8% to 38.8% without a statistically significant temporal trend (OR per year 1.00; 95% CI 0.94-1.07; p = 0.92). URM representation ranged from 2.2% to 12.2% without significant change over time (OR per year 1.06; 95% CI 0.93-1.21; p = 0.36). Compared with published neuroradiology fellowship data, abdominal radiology demonstrated modestly higher female representation but similarly low URM representation.</p><p><strong>Conclusion: </strong>Abdominal radiology fellowships demonstrate persistent gender and racial/ethnic disparities over a decade. These findings underscore the need for targeted, sustained diversity interventions across the diagnostic radiology training pipeline, particularly at earlier stages where efforts may take years to manifest at the fellowship level.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Limited incremental prognostic value of pretreatment MRI and ¹⁸F-piflufolastat PET intensity metrics in grade group ≥ 3 prostate cancer.","authors":"Nuttaphon Aleenajitpong, Rory L Cochran, Sarah Mercaldo, Harleen Kaur, Nabih Nakrour, Isabela C S Lima, Mukesh G Harisinghani","doi":"10.1007/s00261-026-05796-4","DOIUrl":"https://doi.org/10.1007/s00261-026-05796-4","url":null,"abstract":"<p><strong>Background: </strong>Multiparametric MRI (mpMRI) and prostate-specific membrane antigen (PSMA) PET are increasingly used for pretreatment staging of prostate cancer, but their incremental prognostic value for progression-free survival (PFS) beyond clinical variables remains uncertain.</p><p><strong>Objective: </strong>To evaluate whether mpMRI and PSMA PET features independently predict PFS in grade group 3 or higher prostate cancer and add value beyond clinical variables.</p><p><strong>Methods: </strong>This single-center retrospective study included patients with biopsy-proven grade group 3 or higher prostate adenocarcinoma who underwent mpMRI followed by ¹⁸F-piflufolastat PET/CT within 90 days in 2022, with follow-up through March 2026. The primary analysis comprised 101 patients without distant organ metastasis; the full cohort of 127 patients served as a secondary analysis. Clinical, MRI, and PSMA PET variables were evaluated in nested Cox models compared by C-index and likelihood ratio tests.</p><p><strong>Results: </strong>In the primary cohort, 22 of 101 patients (22%) progressed (median follow-up, 3.2 years). Univariably, lower minimum and mean tumor ADC were associated with progression (P = 0.026 and 0.029). In the predefined reduced multivariable model, PI-RADS 5 retained an independent association with worse PFS (HR 5.69, 95% CI 1.13 to 28.65; P = .035; Firth HR 4.44, P = .026), whereas normalized ADC and intensity-based PSMA PET metrics did not. Adding imaging to clinical variables improved neither model fit (likelihood ratio P = .457) nor discrimination (optimism-corrected C-index, 0.77 clinical-only versus 0.73 clinical-plus-imaging). PRIMARY 5 versus 1-4 was not associated with PFS (HR 1.09, 0.45 to 2.60; P = 0.852).</p><p><strong>Conclusion: </strong>Routine quantitative MRI and PSMA PET intensity metrics did not independently predict PFS or improve discrimination beyond clinical variables in grade group 3 or higher prostate cancer. Given the event count, this is a failure to detect incremental value rather than evidence of its absence. The PI-RADS 5 association was imprecisely estimated and is hypothesis-generating.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative identification of adverse pathology in clinically localized clear cell renal cell carcinoma: development and external validation of a contrast-enhanced ultrasound-based model.","authors":"Ji Ma, Zu-Sheng Du, Fang Li, Zhen-Fang Wang, Wenzhi Li, Rong Wu","doi":"10.1007/s00261-026-05795-5","DOIUrl":"https://doi.org/10.1007/s00261-026-05795-5","url":null,"abstract":"<p><strong>Purpose: </strong>To develop and externally validate a model combining contrast-enhanced ultrasound (CEUS), clinical, and laboratory features to identify adverse pathology in clinically localized clear cell renal cell carcinoma (ccRCC).</p><p><strong>Methods: </strong>This retrospective study included 370 surgically treated patients with cT1-T2 ccRCC. Center 1 patients were randomly split into training (n = 210) and internal test (n = 91) sets; Center 2 provided external validation (n = 69). Adverse pathology comprised WHO/ISUP grade 3-4, tumor necrosis, invasion, or nodal metastasis. Two blinded readers assessed images. All 41 preoperative candidates entered logistic least absolute shrinkage and selection operator regression with stratified ten-fold cross-validation and the one-standard-error rule. Internal validation used 200 bootstrap resamples of the complete modeling procedure.</p><p><strong>Results: </strong>Adverse pathology was present in 138 patients. Seven predictors were retained, including four CEUS features. Areas under the receiver operating characteristic curve (AUCs) were 0.810 (95% CI, 0.752-0.868), 0.875 (0.805-0.944), and 0.799 (0.688-0.910) in the training, internal test, and external cohorts, respectively; optimism-corrected training AUC was 0.747. External predictions were compressed (calibration slope, 2.380). At the training-derived threshold of 0.3051, adverse pathology was present in 61.5% (24/39) of external patients with positive results and 6.7% (2/30) with negative results, compared with 37.7% overall.</p><p><strong>Conclusion: </strong>The model showed moderate external discrimination and may support preoperative assessment by identifying patients at lower risk. Prospective multicenter studies are needed to validate individual risk estimates and assess clinical impact.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148984625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymphangiography and lymphatic embolization for post-surgical abdominal leaks.","authors":"Maximilien Lerolle, Lambros Tselikas, Frédéric Deschamps, Paul Beunon, Maximiliano Gelli, Hervé Baumert, Genti Xhepa, Sébastien Gouy, Baptiste Bonnet","doi":"10.1007/s00261-026-05751-3","DOIUrl":"https://doi.org/10.1007/s00261-026-05751-3","url":null,"abstract":"<p><strong>Purpose: </strong>Postoperative intra-abdominal lymphatic leaks are uncommon but clinically significant complications after major abdominal tumor surgery. Conservative management is the standard first-line approach, but refractory cases may require lymphangiography with or without lymphatic embolization. This study evaluated the feasibility, safety, and clinical outcomes of lymphangiography-based management in a tertiary oncologic referral center.</p><p><strong>Methods: </strong>This retrospective single-center study included adult patients referred between January 2015 and January 2025 for postoperative intra-abdominal lymphatic leakage refractory to conservative management. Presentations included isolated chylous ascites, chylous ascites with lymphocele, and isolated lymphocele. The primary endpoint was clinical resolution without repeat intervention after the index lymphangiography. A stricter definition, excluding patients requiring therapeutic paracentesis or drain placement before resolution, was assessed as a sensitivity analysis. Secondary endpoints included technical success, safety, and exploratory factors associated with outcome.</p><p><strong>Results: </strong>Twenty-seven patients underwent 34 lymphangiographic procedures. A lymphatic leak was identified in 23/34 procedures (68%). Embolization was performed in 24/34 procedures (71%) and was technically successful in all cases. Clinical resolution without repeat intervention after the index lymphangiography was achieved in 18/27 patients (67%), while final clinical resolution after one or more lymphangiography-based procedures was achieved in 21/27 (78%). Seven patients required temporary paracentesis or drain placement before recovery, yielding a strict success rate of 14/27 (52%). No procedure-related major complication occurred. High lumbar-aortic leak location was associated with lower clinical resolution in exploratory analysis.</p><p><strong>Conclusion: </strong>In this small, heterogeneous retrospective cohort, lymphangiography with or without embolization appeared feasible and safe for refractory postoperative intra-abdominal lymphatic leaks. Clinical outcomes were sensitive to endpoint definition, and the association between high lumbar-aortic leak location and poorer outcome should be considered hypothesis-generating. Larger prospective multicenter studies are needed to validate these findings.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148979244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventional management of acute mesenteric venous thrombosis: a systematic review of current evidence, emerging techniques and future perspectives.","authors":"Michael Köhler, Ziad Maksoud, Gala Nacul Mora, Gesa Pöhler","doi":"10.1007/s00261-026-05786-6","DOIUrl":"10.1007/s00261-026-05786-6","url":null,"abstract":"<p><p>Acute mesenteric venous thrombosis (aMVT) is a rare but life-threatening form of mesenteric ischemia associated with 30-day mortality of 17-76% without timely therapy. Over the past decade, advances in endovascular technology have transformed the therapeutic landscape. This review comprehensively appraises current evidence on innovative interventional techniques in the management of aMVT, including catheter-directed thrombolysis (CDT), percutaneous mechanical thrombectomy (PMT), large-bore aspiration, transjugular intrahepatic portosystemic shunt (TIPS)-guided approaches, and combined endovascular strategies compared with systemic anticoagulation with regard to recanalization rates and complications in cirrhotic and non-cirrhotic patients. A systematic literature search was conducted across PubMed/MEDLINE and CENTRAL (January 2000 - March 2025). A total of 35 primary studies met inclusion criteria, including 34 (97%) retrospective studies and one (3%) randomized controlled trial. Endovascular therapy was associated with higher recanalization rates (53.8-100%) than systemic anticoagulation (39-85%). TIPS-assisted thrombectomy achieved 100% immediate recanalization and 97% one-year primary portal patency in a non-cirrhotic series, with a 1-year mortality of only 3%. Large-bore aspiration demonstrated 95% technical success and no major bleeding, expanding eligibility to patients with thrombolytic contraindications. In optimally managed interventional settings, there was no need for bowel resection, compared with 5.3-21% in systematic anticoagulation-managed cohorts. Current clinical practice guidelines universally assign interventional modalities to Class IIb/Level C recommendations, substantially lagging behind the clinical evidence. Emerging interventional strategies demonstrate promising recanalization rates with an acceptable complication profile in most studies. This may provide advantages over anticoagulation alone in carefully selected patients with aMVT, although available evidence remains heterogeneous and predominantly observational. An institutional decision tree reflecting current interdisciplinary clinical practice is presented as one illustrative approach to patient stratification and escalation. Future prospective and multicenter studies are required to determine the optimal time and type of endovascular interventions to improve future guideline recommendations in carefully defined patients at tertiary centers.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and safety of percutaneous cryoablation for treatment of peritoneal metastases.","authors":"Jack Rogers, Rebecca Hibbert, Nicholas Larson, Matthew Augustine, Brian Welch, John Schmitz, Ahmad Parvinian","doi":"10.1007/s00261-026-05784-8","DOIUrl":"https://doi.org/10.1007/s00261-026-05784-8","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the feasibility, safety, and local-control outcomes of percutaneous cryoablation for treatment of peritoneal metastases.</p><p><strong>Methods: </strong>Retrospective review of an institutional ablation database identified 28 patients (57% female, mean age 67.7 ± 13.8 years) who underwent 31 cryoablation procedures for treatment of 32 peritoneal metastases between January 2011 and January 2026. Patient characteristics, procedural details, adverse events, and oncologic outcomes were recorded. Adverse events were classified according to Society of Interventional Radiology criteria. Freedom from local progression was estimated at the patient level using an interval-censored Turnbull estimator, with sensitivity analysis estimating cumulative incidence of detected local progression with death considered as a competing event.</p><p><strong>Results: </strong>Technical success was achieved in all 31 procedures. Hydrodisplacement of bowel was performed in 22 procedures (71%). Adverse events occurred after 3 procedures (9.7%), including one major adverse event (3.2%). There was no procedure-related mortality. Patient-level local control failure after the index cryoablation procedure occurred in 10 of 28 patients. Estimated freedom from local progression was 62.7% (95% CI, 37.7%-100%) at 365 days. In competing-risk analysis, the cumulative incidence of detected local progression before death was 28.6% (95% CI, 15.9%-51.3%) at 365 days. New peritoneal metastases outside the ablation zone developed after 21 of 31 sessions (67.7%) at a median of 4.5 months.</p><p><strong>Conclusion: </strong>In selected patients, percutaneous cryoablation of peritoneal metastases was technically feasible with infrequent adverse events. New peritoneal disease was common, supporting a role for cryoablation as an adjunctive focal therapy within a multimodality treatment paradigm rather than as a definitive therapy.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning-based segmentation and detection of focal liver lesions on multi-sequence non-contrast MRI.","authors":"Duoduo Zhang, Ke Wang, Pengsheng Wu, Jialun Li, Xiaodong Zhang, Xiaoying Wang","doi":"10.1007/s00261-026-05785-7","DOIUrl":"https://doi.org/10.1007/s00261-026-05785-7","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the performance of a deep learning-based artificial intelligence (AI) model for the multi-sequence automated segmentation and detection of focal liver lesions (FLLs) on non-contrast MRI (NC-MRI).</p><p><strong>Methods: </strong>A total of 1010 NC-MRI were included as the training set, and 144 consecutive MRI were collected as the hold-out set. The publicly available LLDMMRI-2023 and CHAOS datasets were utilized for external validation. T1WI, fat-saturated T2WI (fsT2WI), and high-b-value DWI (DWI_High) were included. Radiologist annotations on individual sequences served as the reference standard. A two-stage sequential 3D V-Net was implemented for FLLs segmentation. Segmentation performance was assessed using Dice similarity coefficient (DSC). A lesion was considered detected if the DSC between model-predicted mask and reference standard exceeded zero. Detection performance was evaluated using sensitivity at the lesion and patient level, and false-positive lesion per sequence. For verified sensitivity, a lesion on one sequence was considered a true positive if detected on any other sequence for the same patient. Subgroup analyses were performed according to lesion size. Lesions were first split using a 20 mm cutoff, then classified into four size groups: <10 mm, 10-20 mm, 20-40 mm, and ≥ 40 mm. Subgroup analyses comparing benign and malignant lesions were performed in the external validation set.</p><p><strong>Results: </strong>Mean DSC for FLLs segmentation were 0.535, 0.590 and 0.596 for the training, hold-out and external validation sets. Sensitivities in the hold-out set ranged from 0.794 to 0.882 across T1WI, fsT2WI, and DWI_High, with all verified sensitivities > 0.93. In the external validation set, sensitivities were 0.688 (0.640-0.732), 0.864 (0.833-0.891) and 0.918 (0.889-0.941), while verified sensitivities reached 0.978, 0.978 and 0.972, respectively. Per-sequence false positive lesions were 0.50, 1.94, 1.42 for the hold-out set and 0.60, 1.66, 0.90 for the external validation set. Patient-level sensitivity was 0.988 and 0.987 across the two datasets. In the external validation set, DWI_High showed a statistically significant difference in sensitivity between lesions in < 20 mm and ≥ 40 mm subgroups (p < 0.001). For fsT2WI, benign lesions achieved superior detection sensitivity, with significant differences in 10-20 mm (p < 0.001) and 20-40 mm subgroups (p < 0.05). For DWI_High, malignant lesions yielded higher sensitivity in < 10 mm subgroups (p < 0.001).</p><p><strong>Conclusion: </strong>The deep learning-based AI model enables automated segmentation and detection of FLLs on NC-MRI, with acceptable performance across different lesion sizes.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148946560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative dual-layer spectral CT parameters associated with a continuous improvement response pattern to CAPTEM in advanced gastroenteropancreatic neuroendocrine neoplasms.","authors":"Jiadan Luo, Ke Li, Siya Shi, Zujiang Shi, Tingting Wen, Jinhui Yu, Jiaxin Yuan, Jiawei Liu, Yanji Luo","doi":"10.1007/s00261-026-05787-5","DOIUrl":"https://doi.org/10.1007/s00261-026-05787-5","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the prognostic significance of a dynamic continuous improvement (CI) response pattern in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) treated with capecitabine and temozolomide (CAPTEM), and to explore the association between baseline dual-layer spectral CT (DLCT) parameters and this favorable response trajectory.</p><p><strong>Methods: </strong>This single-center retrospective study (May 2016 - September 2025) analyzed 54 patients treated with CAPTEM. Cox proportional hazards regression models were used to identify prognostic factors affecting progression-free survival (PFS). Patients were stratified via 9-month landmark analysis into CI and non-continuous improvement (NCI) groups. PFS and Time to Nadir (TTN) were compared. Baseline DLCT parameters were analyzed for their association with the CI pattern.</p><p><strong>Results: </strong>54 patients (median age, 53 years; 29 men) were evaluated. Peritumoral tissue invasion was independent prognostic factor (p = 0.008; Hazard Ratio [HR], 4.604; 95% confidence interval: 1.495, 14.173). In the landmark cohort, post-landmark PFS was significantly longer in the CI (n = 9) than the NCI (n = 13) group (18.70 vs. 6.47 months; HR, 0.295; 95% confidence interval: 0.100, 0.876; p = 0.044), with a longer TTN (9.67 vs. 6.83 months; p = 0.021). Lower baseline nIC and Zeff values were significantly associated with the CI pattern (median Zeff 8.070 vs. 8.920, p = 0.008; median nIC 0.426 vs. 0.723, p = 0.030).</p><p><strong>Conclusion: </strong>The continuous improvement response pattern was associated with prolonged PFS in GEP-NENs treated with CAPTEM. Baseline DLCT parameters may help identify patients likely to derive sustained benefit from CAPTEM therapy.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148946573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT-derived extracellular volume fraction and AI-assisted body composition for predicting neoadjuvant therapy response and prognosis in colorectal cancer.","authors":"Ting Lu, Long Yuan, Chunyu Zhang, Haiting Yang, Shenglin Li, Junlin Zhou","doi":"10.1007/s00261-026-05718-4","DOIUrl":"https://doi.org/10.1007/s00261-026-05718-4","url":null,"abstract":"<p><strong>Objectives: </strong>To develop a combined model integrating clinical parameters, quantitative parameters from contrast-enhanced computed tomography (CECT), and Artificial Intelligence-assisted body composition metrics for predicting treatment response and prognosis in colorectal cancer (CRC) patients receiving neoadjuvant therapy (NAT).</p><p><strong>Materials and methods: </strong>This retrospective study included CRC patients received NAT and surgery between January 2016 and June 2025. Quantitative CECT parameters (extracellular volume fraction [ECV] and arterial enhancement fraction), and body composition parameters (skeletal muscle index [SMI], skeletal muscle attenuation, and visceral-to-subcutaneous adipose tissue ratio) were measured before and after NAT, and their changes were calculated. Logistic regression analysis was used to identify independent predictors of treatment response. A multivariable logistic regression model was constructed, and evaluated using the area under the receiver operating characteristic curve (AUC). Patients were stratified into high- and low-risk groups based on risk score produced from the model. Cox regression analysis was used to assess association between risk score and prognosis.</p><p><strong>Results: </strong>A total of 163 patients (age, 58.50 ± 10.55 years) were included. A combined model incorporating post-NAT carcinoembryonic antigen, ECV and SMI achieved an AUC of 0.836 (95% CI: 0.754-0.915) and 0.784 (95% CI: 0.583-0.947) in the training and validation cohorts. The risk score was significantly associated with prognosis. High-risk patients had shorter overall survival (Hazard ratio [HR]: 3.745, 95% CI: 1.014-13.836, P = 0.048) and disease-free survival (HR: 2.801, 95% CI: 1.050-7.475, P = 0.040).</p><p><strong>Conclusion: </strong>The combined model may help predict treatment response and survival outcomes in patients with CRC undergoing NAT.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148946569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Augmented and virtual reality for preprocedural planning and intraprocedural guidance in transplant hepatic artery stenting.","authors":"Andrew C Gordon, Saad Abu Zahra, Amir A Borhani, Zach Dietch, Daniel Borja-Cacho, Scott Resnick, Robert J Lewandowski","doi":"10.1007/s00261-026-05777-7","DOIUrl":"https://doi.org/10.1007/s00261-026-05777-7","url":null,"abstract":"<p><strong>Purpose: </strong>Hepatic artery stenosis is a recognized vascular complication after orthotopic liver transplantation, and endovascular treatment is technically demanding because of variable post-surgical anatomy. Augmented and virtual reality (AR/VR) allows immersive review of patient-specific three-dimensional imaging, but its clinical application to transplant hepatic artery interventions remains poorly described. This study evaluated the feasibility, usability, and perceived impact of AR/VR for preprocedural planning and intraprocedural guidance in transplant hepatic artery (HA) stenting.</p><p><strong>Methods: </strong>This IRB-approved single-center pilot study included eight consecutive patients undergoing transplant HA stenting from January 2025 to May 2026. Preprocedural planning was performed using an AR/VR headset and spatial computing software. In the final three cases, AR was used intraprocedurally to display live fluoroscopy during the procedure. Postprocedure surveys assessed workflow integration, anatomic visualization, confidence, usability, and comfort using 5-point Likert scales.</p><p><strong>Results: </strong>Cases were emergent in 12.5% and elective in 87.5%; 62.5% were high complexity. All cases were technically successful without major complications. Median case, fluoroscopy, and AR/VR planning times were 159.5, 34.8, and 4.5 min, respectively; median air kerma was 678 mGy. AR/VR planning represented 3.6% of case time and was perceived to change the approach in 6/8 cases (75%). Visualization, workflow integration, confidence, and anatomic understanding each received median scores of 5. Headset comfort was lowest-rated. Intraprocedural AR was successful in all 3 cases.</p><p><strong>Conclusion: </strong>AR/VR planning for transplant HA stenting is feasible, influencing procedural strategy in 75% of cases with maximum operator ratings for visualization, confidence, and workflow integration. Intraprocedural AR during transradial access was feasible.</p>","PeriodicalId":520541,"journal":{"name":"Abdominal radiology (New York)","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148946571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}