Juntendo medical journal最新文献_第2页

A Survey of Periodic Dental Visits Among Patients Receiving Preoperative Consultations. 接受术前咨询的患者定期牙科就诊的调查。

Juntendo medical journal Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0040-CR

Yoshiko Yamamura, Ryo Umeyama, Junko Yamazaki, Shiho Koroku, Shunsuke Namaki, Seiji Ishikawa, Mitsuyo Shinohara

{"title":"A Survey of Periodic Dental Visits Among Patients Receiving Preoperative Consultations.","authors":"Yoshiko Yamamura, Ryo Umeyama, Junko Yamazaki, Shiho Koroku, Shunsuke Namaki, Seiji Ishikawa, Mitsuyo Shinohara","doi":"10.14789/ejmj.JMJ24-0040-CR","DOIUrl":"10.14789/ejmj.JMJ24-0040-CR","url":null,"abstract":"Objectives: The aim of this study was to examine the correlation between regular dental visits and the oral health status.Design: This was a retrospective study.Methods: We included 3,138 patients who visited the preoperative outpatient clinic and underwent oral examinations between April and September 2020. Patients whose last dental visit occurred less than one year prior to data collection constituted the regular visit group, while the irregular-visit group comprised those with a last dental visit beyond one year prior to data collection. We examined the following information: last dental visit, sex, age, disease causing hospitalization, frequency of daily brushing, presence or absence of moving teeth, and oral hygiene status.Results: The frequency of brushing was lower in the irregular-visit group than in the regular-visit group, suggesting a lower awareness of oral health in the irregular-visit group. Furthermore, the oral hygiene status in the regular-visit group was better than that in the irregular-visit group, with more patients showing no tartar deposition.Conclusions: Regular dental checkups can mitigate perioperative complications, preventing them from adversely affecting the treatment of the underlying disease. It is crucial to emphasize the importance of oral management, explain the need for it, and actively encourage regular dental visits.","PeriodicalId":520470,"journal":{"name":"Juntendo medical journal","volume":"71 2","pages":"121-126"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment Strategy for Long COVID Based on Traditional Chinese Medicine. 基于中医的长期COVID治疗策略。

Juntendo medical journal Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0041-P

Mahiko Nagase, Yuu Takeshita, Kiyohide Tomooka

{"title":"Treatment Strategy for Long COVID Based on Traditional Chinese Medicine.","authors":"Mahiko Nagase, Yuu Takeshita, Kiyohide Tomooka","doi":"10.14789/ejmj.JMJ24-0041-P","DOIUrl":"10.14789/ejmj.JMJ24-0041-P","url":null,"abstract":"Post-acute COVID-19 conditions, commonly known as 'long COVID', occur in individuals with a history of probable or confirmed severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infection, typically 3 months from the onset of COVID-19 with symptoms, lasting for at least 2 months, that cannot be explained by any alternative diagnoses. Although most symptoms improve over time, some patients experience significant limitations in their social lives. Under such circumstances, complementary and alternative medicine (CAM) interventions are growing in popularity as possible treatments for long COVID symptoms. There are a wide variety of CAM interventions, such as traditional Japanese medicine (Kampo medicine) and traditional Chinese medicine (TCM). In this study, we compared three studies using Kampo medicine with those using TCM and concluded that Kampo medicine, which is often practiced in Japan due to its historical background, may have some limitations in managing the diverse symptoms of long COVID because the symptoms of long COVID vary widely. Therefore, we propose that medical examinations based on TCM should also be considered as an alternative treatment strategy for patients with long COVID.","PeriodicalId":520470,"journal":{"name":"Juntendo medical journal","volume":"71 2","pages":"102-105"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contribution of Genetics to Parkinson's Disease and Future Prospects. 遗传学对帕金森病的贡献及未来展望。

Juntendo medical journal Pub Date : 2025-04-03 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0052-P

Manabu Funayama

{"title":"Contribution of Genetics to Parkinson's Disease and Future Prospects.","authors":"Manabu Funayama","doi":"10.14789/ejmj.JMJ24-0052-P","DOIUrl":"10.14789/ejmj.JMJ24-0052-P","url":null,"abstract":"Parkinson's disease (PD) is a systemic neurodegenerative disorder that is characterized by motor and non-motor symptoms. Although aging is the primary risk factor, environmental and genetic factors also contribute to risk, and identifying genetic risks may aid in preventive strategies. The present perspective outlines the two main genetic research strategies: research into familial PD using known causative gene screening and next-generation sequencing, and the analysis of sporadic PD using genome-wide association studies (GWAS). Recent advances in next-generation sequencing have improved gene screening, allowing researchers to quickly and inexpensively identify novel rare variants. However, challenges remain, such as accurately analyzing repetitive sequences and structural variants. The role of neurologists in gathering clinical and genomic data ─ especially from familial cases ─ is crucial. International collaborations, such as the Global Parkinson's Genetic Program, address issues such as population diversity and missing heritability in GWAS. Contributions from Juntendo University include the discovery of PD-related genes and the implementation of validation studies in Japanese populations. We also aim to develop molecular targeted therapies using induced pluripotent stem cells. To elucidate the unknown causes of PD and advance treatment approaches, it is important to continuously conduct genetic research.","PeriodicalId":520470,"journal":{"name":"Juntendo medical journal","volume":"71 2","pages":"76-81"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Applications and Future Prospects of Fecal Microbiota Transplantation. 粪便微生物群移植的应用现状及展望。

Juntendo medical journal Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0045-R

Dai Ishikawa, Xiaochen Zhang, Akihito Nagahara

引用次数: 0

Evidence for Exercise Therapy in Elderly Patients with Rheumatoid Arthritis. 老年类风湿关节炎患者运动治疗的证据。

Juntendo medical journal Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0039-R

Masashi Aoyagi, Hideru Ito, Ryota Kuratsubo, Yuki Shiota, Takayuki Komatsu, Yuji Takazawa

{"title":"Evidence for Exercise Therapy in Elderly Patients with Rheumatoid Arthritis.","authors":"Masashi Aoyagi, Hideru Ito, Ryota Kuratsubo, Yuki Shiota, Takayuki Komatsu, Yuji Takazawa","doi":"10.14789/ejmj.JMJ24-0039-R","DOIUrl":"10.14789/ejmj.JMJ24-0039-R","url":null,"abstract":"Objectives: The number of elderly patients with rheumatoid arthritis (RA) is increasing due to the extension of life expectancy and advances in pharmacotherapy. Although exercise therapy has shown to be effective in patients with RA, there is a lack of evidence specifically focusing solely on elderly patients. We aimed to review the evidence for the effects of exercise therapy on elderly patients with RA.Design: Systematic review.Methods: An electronic search was conducted on June 30th, 2023, in five online databases. Controlled clinical trials investigating the effects of exercise therapy on elderly patients with RA were included. No restrictions were placed on the exercise therapy or outcomes to examine the effects of exercise therapy broadly. The risk of bias in the included studies was assessed using the revised Cochrane risk-of-bias tool for randomized trials and the risk of bias in non-randomized studies of interventions.Results: Out of the 4,177 articles identified, only three studies were included. All three studies were judged to have a high or serious risk of bias. The exercise therapies in the included studies were Arthritis self-management programs, Tai Chi, and grip-strengthening exercise. Arthritis self-management programs and Tai Chi showed the positive effects, whereas grip-strengthening exercise reported no effectiveness.Conclusions: In a few controlled clinical trials, the effects of exercise therapy on elderly patients with RA have been investigated, suggesting that the evidence on these effects is very limited. Considering that the society will continue to age, further studies on this topic are required.","PeriodicalId":520470,"journal":{"name":"Juntendo medical journal","volume":"71 2","pages":"93-101"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining Physical Therapy Students' Subjective Mastery of Simulated Clinical Practice Using Smart Glasses to Share Teacher's Visual Field Information. 利用智能眼镜共享教师视野信息考察物理治疗学生对模拟临床实践的主观掌握。

Juntendo medical journal Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0033-OA

Yoko Takahashi, Tomofumi Yamaguchi, Yoji Sumise, Yuji Fujino, Kenzo Muroi, Tetsuya Takahashi, Toshiyuki Fujiwara, Hiroyuki Daida

{"title":"Examining Physical Therapy Students' Subjective Mastery of Simulated Clinical Practice Using Smart Glasses to Share Teacher's Visual Field Information.","authors":"Yoko Takahashi, Tomofumi Yamaguchi, Yoji Sumise, Yuji Fujino, Kenzo Muroi, Tetsuya Takahashi, Toshiyuki Fujiwara, Hiroyuki Daida","doi":"10.14789/ejmj.JMJ24-0033-OA","DOIUrl":"10.14789/ejmj.JMJ24-0033-OA","url":null,"abstract":"Objectives: Physical therapy education depends on hands-on training. However, the COVID-19 pandemic limited face-to-face demonstrations. This study considers the use of smart glasses, devices that allow real-time information sharing from remote locations. We investigated the efficacy of teachers' use of smart glasses during a class on students' subjective mastery of applying neuromuscular electrical stimulation (NMES).Methods: 119 second-grade students from the physical therapy department were randomly divided into three groups: smart glasses demonstration combined with video watching (smart glasses, n = 40), face-to-face demonstration combined with video watching (face-to-face, n = 40), and video watching only (video only, n = 39). All groups watched a 10-minute video on NMES guidance. The smart glasses group practiced NMES while viewing a shared demonstration via smart glasses worn by the teacher. The face-to-face group received a demonstration from the teacher before practicing NMES. All groups completed a questionnaire on their mastery of NMES.Results: In terms of NMES mastery, 85% of students in the smart glasses group scored the highest, followed by 82% in the face-to-face group and 64% in the video only group. The smart glasses group found it significantly easier to view the device's operating screen during the demonstration than the face-to-face group. Conversely, concentration, and ease of asking questions were significantly higher in the face-to-face group than the smart glasses group.Conclusions: NMES education using smart glasses could be as effective as face-to-face demonstrations in promoting students' subjective mastery, but further actions are needed to compensate for the shortcomings.","PeriodicalId":520470,"journal":{"name":"Juntendo medical journal","volume":"71 2","pages":"106-114"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment Strategy in Reconstructive Microsurgery. 重建显微外科的治疗策略。

Juntendo medical journal Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0053-R

Kazufumi Sano

引用次数: 0

Co-occurrence of Down Syndrome and Multiple Sclerosis. 唐氏综合症和多发性硬化症的共存。

Juntendo medical journal Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0042-R

Yasuhiro Arai, Chihiro Mano

{"title":"Co-occurrence of Down Syndrome and Multiple Sclerosis.","authors":"Yasuhiro Arai, Chihiro Mano","doi":"10.14789/ejmj.JMJ24-0042-R","DOIUrl":"10.14789/ejmj.JMJ24-0042-R","url":null,"abstract":"Object: Down syndrome (DS) is often associated with autoimmune diseases; however, its association with multiple sclerosis (MS) has rarely been reported. In a previous report, the coincidence of DS and MS showed a negative association. Here, we searched for the coincidence of DS and MS, and attempted to resolve this negative association, focusing on the gene dosage effect, by utilizing available reports.Case presentation: A 44-year-old woman with DS experienced a progressively worsening gait at onset. Auto-immuno-antibodies including aquaporin-4 antibody were negative. On the basis of brain magnetic resonance image (MRI) findings, the patient was diagnosed with possible MS. After three years, the patient demonstrated additional signs and regression symptoms. Re-examined brain MRI showed multiple new focal lesions. Based on the McDonald criteria, the patient was diagnosed with laboratory-supported defined MS.Discussion: To date, we have found only one case report in the literature describing the development of MS in a 49-year-old man with DS. The protective effect of DS against the development of MS might be mediated by a gain of function due to a gene dosage effect, and the effect of candidate antigens could be interferon alpha and beta receptors, S100B, and amyloid precursor protein (APP).Conclusions: In patients with DS, S100B and APP overexpression could protect against MS, but both correlate with the progression of Alzheimer's neuropathological changes. S100B and APP can be seemed to be multiple pathogenesis and co-occurrence of MS with DS and Alzheimer's dementia may advance more severely than MS without DS.","PeriodicalId":520470,"journal":{"name":"Juntendo medical journal","volume":"71 2","pages":"115-120"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12086456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Allergic Predisposition on Corneal Biomechanical Properties in Normal Corneas: A Retrospective Study. 过敏倾向对正常角膜生物力学特性影响的回顾性研究。

Juntendo medical journal Pub Date : 2025-01-30 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0028-OA

Sakyo Kanehara, Masahiro Yamaguchi, Yoshimune Hiratsuka, Shiro Amano, Nobuyuki Ebihara

{"title":"Effects of Allergic Predisposition on Corneal Biomechanical Properties in Normal Corneas: A Retrospective Study.","authors":"Sakyo Kanehara, Masahiro Yamaguchi, Yoshimune Hiratsuka, Shiro Amano, Nobuyuki Ebihara","doi":"10.14789/ejmj.JMJ24-0028-OA","DOIUrl":"10.14789/ejmj.JMJ24-0028-OA","url":null,"abstract":"Objective: Pathogenic factors that reduce corneal biomechanical properties (CBPs) remain unclear. This study aimed to retrospectively analyze the effect of allergic predisposition on CBPs in normal corneas.Design: Retrospective study.Methods: Patients with atopic dermatitis (8 eyes), allergic conjunctivitis (18 eyes), vernal conjunctivitis (5 eyes), and atopic keratoconjunctivitis (14 eyes) in their 10s-30s who visited the Juntendo University Hospital were considered to have an allergic predisposition (+). Additionally, 32 eyes were included in the healthy control group without allergic predisposition (-). CBP parameters (Corvis Biomechanical Index, deformation amplitude [DA], peak distance, A1 velocity, and A2 velocity [A2V]) were assessed using Corvis ST (Oculus, Wetzlar, Germany) in all patients. The relationship between the CBP parameters and allergic predisposition was evaluated using multiple linear regression analysis with generalized estimating equations.Results: Corneal shape analysis using CASIA (Tomey Corp., Nagoya, Japan) confirmed that no complications associated with keratoconus were present. Multivariate analysis revealed that an allergic predisposition (+) had a strong influence on A2V (p < 0.001) and that DA was affected by allergic predisposition (p = 0.002).Conclusions: Allergic predisposition may affect CBP parameters in normal corneas, suggesting that A2V may be an early marker of keratoconus onset.","PeriodicalId":520470,"journal":{"name":"Juntendo medical journal","volume":"71 1","pages":"36-42"},"PeriodicalIF":0.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Summary Concerning 16 Years of Research Activities in the Department of Pediatrics at Juntendo University. 顺天堂大学儿科系 16 年研究活动总结。

Juntendo medical journal Pub Date : 2025-01-30 eCollection Date: 2025-01-01 DOI: 10.14789/ejmj.JMJ24-0029-P

Toshiaki Shimizu

{"title":"Summary Concerning 16 Years of Research Activities in the Department of Pediatrics at Juntendo University.","authors":"Toshiaki Shimizu","doi":"10.14789/ejmj.JMJ24-0029-P","DOIUrl":"10.14789/ejmj.JMJ24-0029-P","url":null,"abstract":"I described mainly about my research activities in the 16 years and 8 months since I became professor of pediatrics at Juntendo University. Since the fulfillment of research activities has a great influence on clinical activities, and sufficient research cannot be conducted without enhanced educational activities, I have tried to maintain a good balance between clinical practice, research, and education. Research activities in our department often depend on the research abilities of graduate students, but the leadership skills of the professors and associate and assistant professors who supervise the research are also important. First, I talked about the main research of the 12 research groups in our department. In addition, my specialty is pediatric gastroenterology and nutrition, and it is no exaggeration to say that Juntendo Pediatrics is one of the leaders in the field of pediatric gastroenterology and nutrition. I also provided a detailed explanation of research on pediatric inflammatory bowel disease (IBD), which is currently the most important research topic in our department. I hope that this environment will continue to foster the research mindset of young people in a natural way.","PeriodicalId":520470,"journal":{"name":"Juntendo medical journal","volume":"71 1","pages":"11-25"},"PeriodicalIF":0.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0