Evidence for Exercise Therapy in Elderly Patients with Rheumatoid Arthritis.

Juntendo medical journal Pub Date : 2025-03-12 eCollection Date: 2025-01-01 DOI:10.14789/ejmj.JMJ24-0039-R
Masashi Aoyagi, Hideru Ito, Ryota Kuratsubo, Yuki Shiota, Takayuki Komatsu, Yuji Takazawa
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Abstract

Objectives: The number of elderly patients with rheumatoid arthritis (RA) is increasing due to the extension of life expectancy and advances in pharmacotherapy. Although exercise therapy has shown to be effective in patients with RA, there is a lack of evidence specifically focusing solely on elderly patients. We aimed to review the evidence for the effects of exercise therapy on elderly patients with RA.

Design: Systematic review.

Methods: An electronic search was conducted on June 30th, 2023, in five online databases. Controlled clinical trials investigating the effects of exercise therapy on elderly patients with RA were included. No restrictions were placed on the exercise therapy or outcomes to examine the effects of exercise therapy broadly. The risk of bias in the included studies was assessed using the revised Cochrane risk-of-bias tool for randomized trials and the risk of bias in non-randomized studies of interventions.

Results: Out of the 4,177 articles identified, only three studies were included. All three studies were judged to have a high or serious risk of bias. The exercise therapies in the included studies were Arthritis self-management programs, Tai Chi, and grip-strengthening exercise. Arthritis self-management programs and Tai Chi showed the positive effects, whereas grip-strengthening exercise reported no effectiveness.

Conclusions: In a few controlled clinical trials, the effects of exercise therapy on elderly patients with RA have been investigated, suggesting that the evidence on these effects is very limited. Considering that the society will continue to age, further studies on this topic are required.

老年类风湿关节炎患者运动治疗的证据。
目的:由于预期寿命的延长和药物治疗的进步,老年类风湿关节炎(RA)患者的数量正在增加。尽管运动疗法已被证明对类风湿性关节炎患者有效,但缺乏专门针对老年患者的证据。我们的目的是回顾运动疗法对老年RA患者影响的证据。设计:系统回顾。方法:于2023年6月30日在5个在线数据库中进行电子检索。包括调查运动疗法对老年RA患者影响的对照临床试验。没有对运动疗法或结果进行限制,以广泛检查运动疗法的效果。采用改进的Cochrane随机试验偏倚风险工具和干预措施的非随机研究的偏倚风险评估纳入研究的偏倚风险。结果:在确定的4177篇文章中,只有3篇研究被纳入。所有三项研究都被认为具有高或严重的偏倚风险。纳入研究的运动疗法包括关节炎自我管理项目、太极拳和握力强化运动。关节炎自我管理项目和太极显示出积极的效果,而握力强化运动则没有效果。结论:在一些对照临床试验中,研究了运动疗法对老年RA患者的影响,表明这些影响的证据非常有限。考虑到社会将继续老龄化,这一课题需要进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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