Acta of bioengineering and biomechanics最新文献

{"title":"Usefulness of subtraction thermography in the evaluation of blood vessels and lymphatic vessels in the dental pulp.","authors":"Kamila Wiśniewska, Maria Szymonowicz, Piotr Kuropka, Zbigniew Rybak, Natalia Struzik, Krzysztof D Dudek, Anna Nikodem, Maciej Dobrzyński","doi":"10.37190/abb-02433-2024-04","DOIUrl":"10.37190/abb-02433-2024-04","url":null,"abstract":"<p><p><i>Purpose</i>: Caries or iatrogenic thermal trauma of the teeth have a significant impact on the dental pulp structure connected with stimulation of angiogenesis and lymphangiogenesis. Therefore, the aim of the study was to identify the difference in the rate of heat dissipation by vessels present in the dental pulp. <i>Methods</i>: Freshly extracted healthy (<i>n</i> = 10) and carious (<i>n</i> = 14) molars and premolars were cut on a diamond saw and subjected to active thermographic examination and then subjected to lymphoscintigraphy and X-ray examination. The tooth samples were heated uniformly to 40 ± 0.5 °C. A thermal imaging camera with a resolution of 640 × 320 pixels was used to record the sequence of thermograms during free cooling. Due to the different volume of teeth and different surface conditions of the examined teeth (color, roughness) and the related different radiation emissivity, the changes in the temperature (Δ<i>T</i>) of the tooth cross-section surface were analyzed using the subtractive method within 120 seconds from the switching off of the thermal impulse (heating). <i>Results</i>: Thermographic examination of healthy and cariously changed teeth revealed areas of increased tissue fluid flow combined with heat release, which may indirectly indicate the existence of vessels in these areas. On a thermal imaging camera, variations in the rate of heating or cooling across several cross-sectional sections of the same tooth indicate changes in the dental structure's density. <i>Conclusions</i>: In caries-affected teeth, intracanalicular fluid flows are different than those of healthy teeth. Therefore, it can be concluded that the pulp vessels enabling circulation of body fluids - blood and lymphatic - increases with the intensity of inflammation. Maintaining the homeostasis of the dental pulp depends heavily on the circulation of bodily fluids within the dental organ.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 2","pages":"143-151"},"PeriodicalIF":0.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macrophage activity modulation via synergistic effect of a porous substrate and low-field laser therapy.","authors":"Aleksandra Matuła, Amelia Lizak, Ewa Stodolak-Zych, Beata Stenka, Joanna Homa, Aneta Bac, Aneta Teległów, Anna Ścisłowska-Czarnecka","doi":"10.37190/abb-02451-2024-02","DOIUrl":"10.37190/abb-02451-2024-02","url":null,"abstract":"<p><p><i>Purpose</i>: The aim of this study was to investigate the effect of substrate - polycaprolactone (PCL)-based porous membrane modified with rosmarinic acid (RA), (PCL-RA) and to determine the optimal values of low field laser irradiation (LLLT) as stimulators of biological response of RAW 264.7 macrophages. <i>Methods</i>: The porous polymer membrane was obtained by the phase inversion method, the addition of rosmarinic acid was 1%wt. The reference material was pure polymer membrane. RAW 264.7 were deposited on the material and then irradiated with a laser with a wavelength of 808 nm, a power of 100 mW, an irradiation dose of 2 J/cm2/cell well, applied continuously (C), (100/2/C) or pulsed (I), (100/2/I). <i>Results</i>: Macrophage irradiation resulted in an increase in their adhesion. Modifying the PCL membranes with rosmarinic acid had no effect on cell viability on day 3 of the cell culture. Irradiation of macrophages cultured on PCL-RA material increased their viability. Irradiation of macrophages cultured on PCL-RA material decreased macrophage secretion of NO and protein and the increase in TNF and MCP-1 secretion was only transient on day 3 of culture. <i>Conclusions</i>: Macrophage irradiation had a positive effect on macrophage attachment. Modification of PCL membranes with rosmarinic acid influenced the biological activity of macrophages. Culture of macrophages on rosmarinic acid-modified PCL membranes and simultaneous irradiation of LLLT cells resulted in anti-inflammatory effects.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 2","pages":"159-170"},"PeriodicalIF":0.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic characteristics of a compliant seat coupled with the human body and a manikin during the exposure to the whole-body vibration: effect of the polyurethane foam, the track position and the measurement location.","authors":"Xiaolu Zhang, Sen Lin, Xichen Song, Chi Liu, Yi Qiu","doi":"10.37190/abb-02452-2024-02","DOIUrl":"10.37190/abb-02452-2024-02","url":null,"abstract":"<p><p>Transmissibility is used to assess dynamic responses of the occupant-seat system, and most studies have exclusively assessed the transmissibility from the floor to the cushion or the backrest surface with the human body. In this investigation, the vertical vibration transmitted from the floor to six specific locations both on the seat surface and the frame when the seat was fixed on three positions on the track was examined utilizing an SAE J826 manikin and 12 male adults (0.25 to 20 Hz) for a duration of 120 seconds at three vibration amplitudes. The transmissibility from the floor to the headrest frame, the cushion surface, the headrest surface, the seat back frame, and the seat back surface all exhibited a principal peak frequency within 4-5 Hz. With the exception of the cushion frame, the principal peak frequency and the peak transmissibility in transmissibilities to all positions decreased with increasing vibration amplitude, indicating the non-linearity within the occupant-seat system. It was also found modifying seat track positions minimally affected the seat transmissibility to either the surface or the frame of the seat. Polyurethane foam amplified vibration at peak frequency, simultaneously enhancing static sitting comfort and reducing the vertical vibration transmission above peak frequency.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 2","pages":"105-114"},"PeriodicalIF":0.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the mechanical characteristics of porcine brain tissue in complex environments.","authors":"Weiqi Li, Peiming Zhang","doi":"10.37190/abb-02458-2024-03","DOIUrl":"10.37190/abb-02458-2024-03","url":null,"abstract":"<p><p><i>Purpose</i>: Brain tissue immersed in cerebrospinal fluid often exhibits complex mechanical behaviour, especially the nonlinear stress- strain and rate-dependent responses. Despite extensive research into its material properties, the impact of solution environments on the mechanical behaviour of brain tissue remains limited. This knowledge gap affects the biofidelity of head modelling. This study aimed to investigate the effect of solution environments on brain tissue under quasi-static and dynamic loading conditions. <i>Methods</i>: Porcine brain tissue was characterized in compression through quasi-static nonlinear testing and Dynamic Mechanical Analysis under various environments: air, physiological saline and artificial cerebrospinal fluid. Frequencies from 0.1 to 40 Hz were applied to determine dynamic behaviour, while brain samples were compressed up to a 0.3 strain level to obtain nonlinear response. The effects of strain, frequency and solution environment on the mechanical response of brain tissue were statistically evaluated. <i>Results</i>: As environmental conditions transitioned from air to artificial cerebrospinal fluid, the average stress of brain tissue increased by approximately 1.3, 1.3 and 1.4 times at strain levels of 0.1, 0.2 and 0.3, respectively. A statistically significant increase in dynamic storage and loss moduli was observed between air and artificial cerebrospinal fluid environments. At frequencies above 18 Hz, the tan delta in air was significantly lower. <i>Conclusions</i>: The mechanical characterization of brain tissue exhibited a dependency on solution environment under both quasi-static and dynamic loading conditions. Brain tissue showed higher stress levels and dynamic modulus in solution environments compared to an air environment. The results of this study are valuable for improving head simulations and brain material models.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 2","pages":"135-142"},"PeriodicalIF":0.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biomechanical study of elbow joint: different stages after the elbow anterior capsule injury.","authors":"Fang Wang, Botian Tian, Mingxin Li, Xinjie Chang, Yubo Fan","doi":"10.37190/abb-02436-2024-02","DOIUrl":"10.37190/abb-02436-2024-02","url":null,"abstract":"<p><p><i>Purpose</i>: Elbow contracture is a common complication post-elbow trauma, the biomechanical environment after anterior capsule injury was complex. This study aimed to use a finite element model to investigate the biomechanical environment within elbow capsule and its surrounding tissues at various stages after anterior capsule injury. <i>Methods</i>: A finite element model of the elbow joint, incorporating muscle activation behavior, was developed to simulate elbow flexion under normal condition (no injury) and at 2, 4, 6 and 8 weeks following anterior joint capsular injury. The model was used to analyze von Mises stress distribution and changes within the elbow tissues. <i>Results</i>: At no injury condition, and 2, 4, 6 and 8 weeks, the stress of the anterior articular capsule at 60° flexion were 2.62, 3.87, 4.40, 4.57 and 5.24 MPa, respectively. Under normal conditions, and at 2, and 4 weeks, the ulnar cartilage attained its peak stress at 75°. In normal conditions, the highest stress in the ulnar cartilage was 1.08 MPa, amounting to 1.02 times and 1.05 times the stress observed at 2 and 4 weeks, respectively. At 4 weeks, compared with 6 weeks, the stress of the anterior bundle at 15, 30, 45 and 60° was reduced by 11.1, 22.6, 37.3 and 36.1%, respectively. At 6 and 8 weeks, the peak stress in the posterior articular capsule reached 11.5 and 11.7 MPa, respectively, showing minimal variation. <i>Conclusions</i>: The results could offer theoretical basis for rehabilitation professionals in treating and preventing elbow capsule contracture.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 3","pages":"3-11"},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The design of a striking dummy and the theoretical foundations of martial arts strikes.","authors":"Soyib Tajibaev, Mike Loosemore, Ganisher Ismoilov, Nargiza Yusupova, Ravshan Abdukhamidov, Shakhboz Nabiev, Andrey Ovsyannikov, Abdulaziz Kakhkhorjonov","doi":"10.37190/abb-02466-2024-04","DOIUrl":"10.37190/abb-02466-2024-04","url":null,"abstract":"<p><p><i>Purpose:</i> The aim of the research was to develop the design of a striking dummy and the theoretical foundations of martial arts strikes and to test its effectiveness in a pedagogical experiment. This paper presents the design of a striking dummy and the foundational theories behind martial arts strikes. We used modern microelectronics, including a diverse range of sensors, for executing a multitude of electromechanical measurements. Furthermore, we developed a software package for collecting, analysing and storing data from sports training. <i>Methods</i>: The TaePunchBag program, part of this setup, integrates several combat sports including boxing, taekwondo, kickboxing, karate and hand-to-hand combat. It classifies and evaluates various types of hand and foot strikes, conducting specialized tests to measure attributes such as speed, response to signals, force up to 800 kg and impact accuracy. <i>Results</i>: The article details the tasks and operation of the \"Software complex for measuring sportsmen's blows\". Additionally, the advanced range of microelectronic sensors supports various electromechanical measurements, further complemented by a software package that handles data collection, analysis and storage from sports training. <i>Conclusions</i>: The application of this sophisticated software system to martial arts strike measurements, particularly in conjunction with a novel punching bag apparatus, may significantly improve our understanding of impact kinetics. This integrated approach is expected to produce accurate and reliable data on punch and kick power, enabling coaches and athletes to refine training strategies and boost their output.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 3","pages":"47-60"},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isokinetic strength and jumping abilities of teenage soccer players playing in different field positions.","authors":"Michał Górski, Adrian Wilk, Anna Pastuszak, Michał Starczewski, Bartłomiej Michalak, Michael T Lane, Krzysztof Buśko","doi":"10.37190/abb-02470-2024-02","DOIUrl":"10.37190/abb-02470-2024-02","url":null,"abstract":"<p><p>Soccer is a sport being performed in a very dynamic manner. It requires soccer players to be able to develop high muscle force in a very short period of time. The aim of the study was to evaluate the strength and jumping abilities of young soccer players playing in different positions on the field. The study included 49 adolescent soccer players: 6 goalkeepers, 15 defenders, 17 midfielders and 11 strikers. We measured peak torques (PT), total work (TW), and average power (AP) developed by the knee flexors and extensors under isokinetic conditions at angular velocities of 60°⋅s^-1, 180°⋅s^-1 and 300°⋅s^-1 on a Biodex dynamometer, and jump height (<i>H</i>) and maximum power (<i>P</i> _max) on a force plate. PT, AP, TW, and <i>P</i> _max scores were normalized relative to body mass. There were no statistically significant differences between measurements of basic somatic characteristics (body height and body weight), age and biological age as well as PT, AP, TW, H, and <i>P</i> _max in players from different positions on the field. Unlike defenders, midfielders showed a significant correlation of isokinetic tests indices with jump height (<i>r</i> = 0.54÷0.84) and maximum relative power (<i>r</i> = 0.55÷0.76). The differences in correlations are probably due to the different tasks and activities that players in different positions on the field perform during the game.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 3","pages":"13-23"},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinetic characterization of adolescent scoliosis patients with Lenke 1B.","authors":"Huai Wang, Rongchang Fu, Kewei Yang","doi":"10.37190/abb-02469-2024-03","DOIUrl":"10.37190/abb-02469-2024-03","url":null,"abstract":"<p><p><i>Purpose</i>: The purpose of this study was to investigate dynamic responses of Lenke1B+ spines of adolescent scoliosis patients to different frequencies. <i>Methods</i>: Modal analysis, harmonic response analysis and transient dynamics of a full spine model inverted by the finite element method using Abaqus. <i>Results</i>: The first-order axial resonance frequency of 4.51 Hz produced a maximum axial displacement of 30.15 mm. Comparison of the five frequencies indicated that the 10 Hz frequency response curve was smoothest, while the amplitude-frequency curve at 4 Hz showed the greatest fluctuations accompanied by resonance phenomena. At the resonance frequency, the maximum axial displacement of the thoracic spine was at T1, being 31.17 mm, while that of the lumbar spine was at L1, with 0.56 mm. The maximum stress of the intervertebral discs was located between T4 and T5, representing 3.496 MPa, the maximum stress in the small joints was located in the concavity between T7 and T8, with 19.97 MPa and the maximum axial displacement was 54.31 mm, located in the convexity between T6 and T7. <i>Conclusions</i>: The first-order axial resonance frequency was the most harmful to the patient. The uneven stress distribution in the spine was closely related to the degree of spinal deformity, with the thoracic spine being more sensitive to low frequencies than the lumbar spine. The concave side of the spinal deformity was more prone to stress concentrations while the convex side was more prone to deformity, indicating that disc degeneration and small-joint disease are more likely to occur at the most deformed part of the spine.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 3","pages":"75-86"},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between body composition variables, plantar pressure and pain level.","authors":"Svitlana Dikhtyarenko, Pedro Forte, Dulce Esteves","doi":"10.37190/abb-02437-2024-03","DOIUrl":"10.37190/abb-02437-2024-03","url":null,"abstract":"<p><p>From a current perspective, it is understood that body posture is influenced by individual asymmetries, cultural context, habitual body patterns, etiological factors and psychosocial factors allocated to the individual. Clarifying the musculoskeletal cause that originated the postural alteration is considered the clinical challenge in the treatment of pain or discomfort. Recent studies have shown the influence of changes in body weight on the distribution of plantar pressure and foot pain, emphasizing the importance of understanding these relationships. Integrating body composition with plantar pressure analysis presents an opportunity to explore gender differences and their associations with plantar pressure distribution. There is currently a lack of research integrating body composition, plantar pressure distribution and gender comparison to elucidate the complex interaction between these variables. Therefore, the main objective of this investigation is to evaluate body composition through BIA (bioimpedance) and the distribution of plantar pressure in the subjects' feet through pressure platform analysis with a specific focus on comparisons between the genders and the associations between these variables. The study employed an observational cross-sectional design. A total of 77 participants (<i>n</i> = 77) aged between 18 and 91 years were assessed, the majority of whom were female (<i>n</i> = 53, 68.83%), while 24 participants (<i>n</i> = 24, 31.17%) were male. The average age of the participants was 60.717 years for males and 54.33 years for females. Baropodometry and bioimpedance tests were carried out. Significant differences with a medium effect were recorded only for the three indicators, while the rest of the values showed a large effect. Significant negative correlations were found between age and height ( <i>p</i> < 0.05) and positive correlations between age and other factors such as BMI, fat mass, lean mass and various foot-related metrics. The results of this study showed that plantar pressure characteristics differ according to gender and are related to body composition and pain level.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 3","pages":"87-96"},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of heat treatment method on selected physicochemical and biological properties of fluoride-substituted calcium apatite.","authors":"Sylwia Zawiślak, Joanna Rutkowska, Marta Trzaskowska, Krzysztof Pałka, Leszek Borkowski","doi":"10.37190/abb-02484-2024-04","DOIUrl":"10.37190/abb-02484-2024-04","url":null,"abstract":"<p><p><i>Purpose</i>: The synthesis of fluoridated apatite consists of several stages, among which the heat treatment has a significant impact on the physical and chemical properties. The present study aims to elucidate the influence of two different sintering methods on fluoride-substituted apatite properties. <i>Methods</i>: For this purpose, a two F-substituted apatites were produced by heat treatment in different ways called \"rapid sintering\" and \"slow sintering\". Physicochemical properties of the obtained materials were analyzed using infrared spectroscopy, scanning electron microscopy with energy dispersive spectrometry, X-ray diffraction, and mercury intrusion porosimetry. Cytotoxicity of materials was assessed using MTT test. <i>Results</i>: Sintering conditions significantly influenced some porosity parameters of the materials. The samples subjected to \"rapid sintering\" showed a larger total pore area and mercury intrusion volume, while the samples subjected to \"slow sintering\" showed higher average pore diameter. Other porosity parameters did not differ significantly between the tested materials. The crystalline phases and chemical compositions of both materials were the same. Both materials appeared to be non-toxic since their extracts did not caused reduction in the viability of MC3T3-E1 cells compared to control cells and the results obtained were similar for both materials. <i>Conclusions</i>: Sintering is an important step in the apatite synthesis process. The way apatite is sintered is a factor that influences its physicochemical properties. The study performed on fluoride-substituted apatite showed that sintering conditions influenced some porosity parameters but had no effect on composition, chemical structure or crystalline phase. The cytotoxicity of both materials was at the same level, indicating that both were non-toxic.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"26 3","pages":"183-191"},"PeriodicalIF":0.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}