Acta of bioengineering and biomechanics最新文献

{"title":"A comprehensive experimental study on head trauma in a 3-year-old child due to unmanned aerial vehicle collisions.","authors":"Rafał Perz, Igor Dąbrowski, Filip Zakrzewski, Michał Kuminiarczyk, Antoni Kopyt","doi":"10.37190/abb-02365-2023-03","DOIUrl":"https://doi.org/10.37190/abb-02365-2023-03","url":null,"abstract":"<p><p><i>Purpose</i>: This research aimed to evaluate the biomechanical impact on a 3-year-old child's head during collisions with unmanned aerial vehicles (UAVs), focusing on the effects of UAV mass, impact velocity, and impact direction, using the Head Injury Criterion (HIC) for assessment. <i>Methods</i>: Experiments simulated impacts with UAVs of varying masses (249, 500 and 900 g) and velocities (19.0, 24.0 and 29.0 m/s) from different directions. HIC values were measured for each scenario and analyzed in relation to the Abbreviated Injury Scale to determine potential injury severity. <i>Results</i>: The findings showed that both the UAV's mass and impact velocity have a significant influence on the HIC value, with higher figures indicating a greater risk of serious injury. For the UAVs weighing 249 g and 500 g, frontal impacts resulted in the highest HIC values; however, for the UAV weighing 900 g, the highest HIC value occurred for the back hit. Moreover, injury risk was found to escalate non-linearly with increased velocity, especially for heavier UAVs. <i>Conclusions</i>: The study emphasizes the critical influence of UAV mass and impact velocity on the severity of head injuries in children. Increased mass and velocity correlated with higher HIC values, indicating a greater likelihood of severe injury. Frontal impacts were particularly hazardous for lighter UAVs, while rear impacts were more dangerous for heavier UAVs. These findings support the need for stringent regulations on UAV operational parameters, focusing on speed and mass limitations, to mitigate the risk of severe head injuries in children.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"121-132"},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poly(lactide-co-glycolide) microspheres with good biocompatibility.","authors":"Runze An, Wenmin Tang, Zhanpeng Zhao, Wentao Liu, Liang Kan","doi":"10.37190/abb-02359-2023-06","DOIUrl":"https://doi.org/10.37190/abb-02359-2023-06","url":null,"abstract":"<p><p><i>Purpose</i>: Curcumin and icariin have multiple pharmacological effects and are widely used in various fields, but their short half-life, poor bioavailability and low water solubility greatly limit their application in clinical medicine. Poly(lactide-co-glycolide) (PLGA) loaded microspheres not only solve these problems, but also have no toxicity in degradation. <i>Methods</i>: To verify whether PLGA drugloaded microspheres have good biocompatibility, the present experiments used the emulsification-solvent evaporation method to prepare PLGA drug-loaded microspheres and successfully performed the loading of curcumin and icariin. <i>Results</i>: The scanning electron microscopy showed that the particle sizes of the PLGA microspheres were 2-15 μm, icariin/PLGA microspheres were 3-22 μm and curcumin/PLGA microspheres were 5-30 μm. Moreover, the surface of the microspheres was smooth and spherical. Furthermore, the drug loading and encapsulation rate were good. <i>In vitro</i> experiments revealed that the prepared PLGA microspheres were safe and nontoxic, and that they could release drugs stably and slowly. Moreover, their proliferation ability was unaffected after inoculation into bone marrow mesenchymal stem cells (BMSCs), and Alcian blue Staining was performed at last, demonstrating their biocompatibility and important applications in tissue engineering.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"111-120"},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protocol: a randomized parallel-group study of women after hallux valgus correction surgery to compare the effects of \"core foot system\" training vs. traditional rehabilitation methods.","authors":"Mateusz Baran, Paweł Kołodziejski, Katarzyna Kaczmarczyk","doi":"10.37190/abb-02332-2023-03","DOIUrl":"10.37190/abb-02332-2023-03","url":null,"abstract":"<p><p><i>Purpose</i>: The aim of this study is to compare the effects of Core Foot System muscle training vs. traditional rehabilitation methods in female patients after a hallux valgus correction surgery. <i>Methods</i>: The project will involve 60 women who have undergone a Scarf osteotomy to correct the deformity. Participants will be divided into a control and experimental group. The experimental group will follow the Core Foot System protocol, whereas the control group will perform standard lower-limb exercises. Outcome measures will be collected twice: before the intervention and after eight weeks. Gait will be assessed using the Zebris FDM-2 platform, measuring ground reaction forces during walking. <i>Results</i>: The effects of the exercises on the cross-sectional area of the abductor hallucis muscle and the flexor digitorum brevis muscle will be measured. Foot architecture and arch height will be measured using a podoscope. In addition, the participants will complete the Short Form Health Survey and the American Orthopaedic Foot and Ankle Society questionnaires. <i>Conclusions</i>: The study is expected to provide evidence of the effectiveness of foot muscle training using the protocol. The findings may lead to an improved protocol of rehabilitation in patients after a correction surgery that may result in improved gait parameters and quality of daily life. In the future, an improved therapeutic method should make it possible to boost the effectiveness of physiotherapy in patients after a corrective surgery in the forefoot area. The study has been registered with clinicaltrials.org (NCT05210127; 13 January 2022).</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"103-109"},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Underwater and surface tethered swimming, lower limb strength, and somatic traits as the basic indices of young swimmers' sprint performance.","authors":"Kamil Sokołowski, Raul F Bartolomeu, Piotr Krężałek, José A Bragada, Tomasz Pałka, Dorota Ambroży, Marek Strzała","doi":"10.37190/abb-02336-2023-04","DOIUrl":"https://doi.org/10.37190/abb-02336-2023-04","url":null,"abstract":"<p><p><i>Purpose</i>: The ability to swim fast underwater is believed to be connected to lower limb strength and some somatic traits. The main purpose of the study was to evaluate strength and speed parameters based on the relationship between the strength of underwater dolphin kicks and the countermovement jump test (<i>CMJ</i>) among adolescent swimmers. <i>Methods</i>: 48 adolescent male swimmers (13.47 ± 0.84 years) were examined for muscle mass of arms (<i>m</i> _{m arms}), trunk (<i>m</i> _{m trunk}), and legs (<i>m</i> _{m legs}), body height (<i>BH</i>), and biological age (<i>BA</i>). An underwater tethered dolphin kicking test was conducted in a pool; average force (5<i>F</i> _ave) and impulse per single cycle (5<i>I</i> _ave) in the 5-second period were measured. Force indices (20<i>F</i> _ave - average force from 20 seconds and 20<i>I</i> _ave - average impulse per single cycle from 20 seconds) were also measured in 20-second tethered front crawl swimming. During <i>CMJ</i> testing, general lower body muscle motor capabilities were evaluated by extracting the work (<i>CMJw</i> [J]) and height (<i>CMJh</i> [m]) of the jump. <i>Results</i>: The strongest correlations were observed between: (a) 5<i>F</i> _ave and <i>BH</i>, <i>m</i> _{m arms} and <i>CMJw</i>; (b) <i>CMJw</i>, <i>m</i> _{m arms}, and 20<i>F</i> _ave; (c) indices of swimming speed and <i>5I</i> _ave (<i>BA</i> control); (d) total swimming velocity and average tethered swimming force (<i>BA</i> control). Moderate partial correlations (<i>BA</i> control) were noted between speed indices of swimming race and <i>CMJ</i>. <i>Conclusions</i>: The underwater tethered dolphin kick test is a useful predictor test of 50-m front crawl performance in young male swimmers, with better specificity for swimmers than <i>CMJ</i> results themselves.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"81-91"},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on glass-forming ability and corrosion performance of Ca-based biomedical materials.","authors":"Jing Feng, Yue Wang, Dehua Liu, Yong Zhang, Guihong Geng","doi":"10.37190/abb-02338-2023-03","DOIUrl":"https://doi.org/10.37190/abb-02338-2023-03","url":null,"abstract":"<p><p>Stress shielding and the need for secondary surgery are the two major challenges faced by permanent metallic implants, and the emerging Ca-Mg-Zn calcium-based bulk amorphous alloys, with Young's modulus comparable to that of human bone, good biocompatibility, and in vivo degradation, are highly promising materials for bioimplants. Few studies have been reported on the glass formation ability (GFA) and corrosion degradation behavior of Ca-Mg-Zn amorphous alloys in the human body. In this work, we discuss a study on Ca_53+<i>x</i> Mg₂₀Zn_27-<i>x</i> (<i>x</i> = 0, 2, 4, 6, 8, 10) alloys, focusing on changes in Zn content near eutectic points and their impact on microstructure and biological corrosion behavior. A copper mold spray casting method has been developed to prepare amorphous bar alloys and amorphous crystalline composite bar alloys with a diameter of 3 mm, which has been verified by X-ray diffraction, electrochemical treatment, and immersion tests. The experimental results demonstrated that the Ca₃Zn and CaZn₂ phases were precipitated in the 3 mm bar material Ca_53+<i>x</i> Mg₂₀Zn_27-<i>x</i> (<i>x</i> = 0, 2, 4), and Ca_53+<i>x</i> Mg₂₀Zn_27-<i>x</i> (<i>x</i> = 6, 8, 10) was completely amorphous. The Ca₆₃Mg₂₀Zn₁₇ alloy showed the best glass-forming ability, while the Ca₅₉Mg₂₀Zn₂₁ alloy exhibited superior corrosion resistance. Cytotoxicity experiments showed that Ca-Mg-Zn alloys have good biocompatibility and can be used as biomedical materials.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"93-101"},"PeriodicalIF":0.0,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing ligament prestrain in a multibody model of an ankle joint with random sampling.","authors":"Adam Ciszkiewicz","doi":"10.37190/abb-02401-2024-01","DOIUrl":"https://doi.org/10.37190/abb-02401-2024-01","url":null,"abstract":"<p><p><i>Purpose</i>: Modeling an ankle joint is a challenge, especially when considering complex phenomena such as prestrain. In the literature two main approaches to ligament prestrain can be found in ankle modeling. The first one assumes a strain-free configuration, effectively omitting the prestrain, while in the second one the slack lengths are obtained by shortening the ligament lengths in the rest configuration by 2%. These approaches were not compared directly in a controlled environment. <i>Methods</i>: The aim of the study to compare the two common approaches to ligament prestrain in ankle joint modeling. The approaches are compared on a collection of models generated by random sampling from a 6-link, 2-contact pair multibody model of the ankle. Random sampling includes perturbation of slack lengths, which makes the generated models prestrained and with known output characteristics. Their resemblance to the original model and the ankle joint makes them viable for using in a prestrain comparison. Each generated model is prestrain with the two approaches, then the outputs are compared to determine, which approach returns results closer to reality. <i>Results</i>: The comparison was performed on 592 generated models. On average, the strain-free approach significantly outperformed the 2% shortening. <i>Conclusions</i>: The method for testing prestrain proposed in the paper is an effectively tool for exploring the solution space of the model. The obtained results were interesting, but should be taken with caution as they are connected to the test condition. However, the method is general and could used with any other biomechanical model.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"3-10"},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioactive glasses enriched with zinc and strontium: synthesis, characterization, cytocompatibility with osteoblasts and antibacterial properties.","authors":"Lidia Ciołek, Milena Chraniuk, Piotr Bollin, Monika Biernat, Mirosława Panasiuk, Dawid Nidzworski, Beata Gromadzka, Zbigniew Jaegermann, Elżbieta Pamuła","doi":"10.37190/abb-02339-2023-02","DOIUrl":"https://doi.org/10.37190/abb-02339-2023-02","url":null,"abstract":"<p><p><i>Purpose</i>: The aim of the presented work was to characterize the new obtained bioglasses and assess their biological performance <i>in vitro</i>. Bioglasses were produced using the sol-gel method in the SiO₂-P₂O₅-CaO system, for the purpose as composite ingredients. Their chemical composition was enriched with ZnO to introduce antibacterial properties and SrO with osteoinductive effect. The properties of bioglasses were compared and the effect of chemical composition and particle size on their biological properties was assessed. <i>Methods</i>: The bioglasses were evaluated via TG-DTA, FTIR, SEM-EDS analyses before and after incubation in SBF solution. LDH and WST-1 tests were used to determine the level of cytotoxicity of the tested bioglasses on hFOB1.19 osteoblasts. <i>Results</i>: The results show that the developed bioglasses release Ca²⁺, are bioactive in SBF solution, not cytotoxic and show antibacterial activity in contact with <i>Pseudomonas aeruginosa</i> and <i>Staphylococcus aureus</i> strains. Bioglasses enriched with ZnO show the highest bactericidal activity. All tested bioglasses enhanced hFOB 1.19 cells proliferation. Particle size has a lower effect on biological performance of the bioglasses than their chemical composition. <i>Conclusions</i>: The conducted research showed that bioglass modification with SrO and ZnO can be considered particularly for the development of biomaterials supporting bone regeneration and the treatment of infected bone defects.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"69-80"},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contribution of ligaments to intersegmental stability following type II odontoid fracture.","authors":"Dávid Danka, Imre Bojtár","doi":"10.37190/abb-02362-2023-03","DOIUrl":"https://doi.org/10.37190/abb-02362-2023-03","url":null,"abstract":"<p><p><i>Purpose</i>: Management of Anderson and D'Alonzo type II odontoid fractures continues to be controversial despite extensive research and increasing prevalence. To the authors' knowledge, the three odontoid ligaments, the alar ligament, the vertical portion of the cruciate ligament, and the transverse ligament, have not been biomechanically examined in type II odontoid fracture in spite of their potential significance in management. Therefore, this study aims to explore the intersegmental rotations of the craniovertebral junction following Anderson and D'Alonzo type II odontoid fracture and various combinations of ligament ruptures. <i>Methods</i>: A validated C0-C7 cervical spine finite element model was employed to address the research objectives. The model was subjected to flexion-extension, lateral bending, and axial rotation under eight distinct injury conditions apart from the intact state. Prescribed rotations were applied to the top of the cranium while the C7 inferior surface was fixed. Rotation-moment data were retrieved from the model. <i>Results</i>: Type II odontoid fracture caused mixed forms of instability considering flexion-extension. In lateral bending, the fracture alone did not have a significant effect, whereas the disruption of ligaments led to moderate rotation increments. Notably, in axial rotation, the fracture was the most crucial factor for stability. <i>Conclusions</i>: Overall, type II odontoid fracture was found to be the main destabilizing element. Nonetheless, the vertical cruciate and the transverse ligament played a modest role in stabilization. The alar ligament provided minimal or no stability. Furthermore, instances were observed where both the vertical cruciate and the transverse ligament were necessary to prevent more instability.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"59-68"},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adipose-derived stem cells and ginkgo biloba extract-loaded PCL/gelatin nanofibrous scaffolds for peripheral nerve injury repair: the impact of physical activity.","authors":"Hua Gong, Zhengtian Chen","doi":"10.37190/abb-02323-2023-06","DOIUrl":"https://doi.org/10.37190/abb-02323-2023-06","url":null,"abstract":"<p><p>Peripheral nerve damages take place as a result of trauma, compression or disease, resulting in sensory loss, impaired motor function and subsequent challenges. In the current study, ginkgo biloba extract was loaded into PCL/gelatin scaffolds through electrospinning method. The scaffolds were characterized <i>in vitro</i> using various studies. The prepared nanofibrous scaffolds were rolled up to make neural guidance channels. Then, the conduits were seeded with adipose-derived stem cells and transplanted into a rat model of sciatic nerve injury. The scaffolds were not toxic and had optimal tensile and suturability. The animals treated with the conduits that delivered adipose-derived stem cells and ginkgo biloba extract, and received the treadmill exercise, had significantly higher motor and sensory functions recovery. In addition, histopathological examinations showed beneficial role of the exercise plan on the nervous system repair.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"35-47"},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of wearing high-heeled shoes on postural control and foot loading symmetry.","authors":"Michalina Błażkiewicz, Anna Hadamus","doi":"10.37190/abb-02337-2023-02","DOIUrl":"https://doi.org/10.37190/abb-02337-2023-02","url":null,"abstract":"<p><p><i>Purpose</i>: This study aimed to evaluate the effects of high-heeled shoes (HHS) and experience with such footwear on foot loading and standing balance using linear and nonlinear methods. <i>Methods</i>: Sixteen young female experts in wearing high-heeled shoes (HHE) and sixteen young females who occasionally wore high-heeled shoes (HHO) completed a Fall Risk Test (FRT) on the Biodex Balance System platform. They also underwent a both-leg standing test on the Zebris pressure mapping platform, both barefoot and while wearing 11 cm HHS. The study analyzed several parameters, including the FRT index, foot loading parameters, linear measures of postural stability (Center of Pressure (CoP) path length and velocity), and nonlinear postural control measures (sample entropy - SampEn, fractal dimension - FD, and the largest Lyapunov exponent - LyE). <i>Results</i>: HHS caused a significant increase the fall risk of more than 44%, but only in the HHE group. The presence of HHS caused a significant increase in CoP path length and CoP velocity by almost 78%. The values of these parameters increased by more than 67% in the HHO group and by more than 92% in the HHE group. HHS caused a significant increase in the values of nonlinear measures (FD and LyE) in the mediolateral direction. Higher FD and LyE values suggest the ability to react faster to destabilizing stimuli and better balance control related to plasticity and adaptability to new conditions. HHS also led to up to 70% loading on the supporting limb. <i>Conclusions</i>: High heels in the population of young women significantly worsen static balance.</p>","PeriodicalId":519996,"journal":{"name":"Acta of bioengineering and biomechanics","volume":"25 4","pages":"49-57"},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}