Jose Luis Antonaya-Martín, Martín Laguna-Martos, Álvaro Abad-Abad, Noelia Rivas-Martín, Miriam Fernández-Pascual, Rocío Cascos
{"title":"Ovoid Emergence Profile Implant Restoration Design for Stabilization and Improvement of Peri-Implant Soft Tissue: Case Series and Technical Report.","authors":"Jose Luis Antonaya-Martín, Martín Laguna-Martos, Álvaro Abad-Abad, Noelia Rivas-Martín, Miriam Fernández-Pascual, Rocío Cascos","doi":"10.1563/aaid-joi-D-25-00051","DOIUrl":"10.1563/aaid-joi-D-25-00051","url":null,"abstract":"<p><p>This case series evaluated the peri-implant soft tissue improvement with an ovoid emergence profile implant restoration design on internal conical connection dental implants. An extrapolished zirconia monolithic 360° ovoid design critical contour, like \"lollipop,\" with a similar cement-enamel junction (CEJ) of replaced tooth, was used on an original titanium abutment, CAD/CAM abutment (TiBase), or multiunit abutment, with a minimum height of 3 mm and a concave design, to improve an optimal implant-supported restoration emergence profile that can stimulate peri-implant soft tissues due to the pressure and suction that generate a mechano-transduction response of soft tissue cells. Nine cases were rehabilitated using a full digital workflow and an ovoid emergence profile design, with follow-up at 6 months. A visual comparison was made between the placement photographs and the follow-up appointment photographs to assess the changes in peri-implant soft tissues over each period. In all cases, a visual soft tissue improvement can be appreciated, which seems to be an increase in soft tissue volume and the creation of new papillae. Within the limitations of this case series, it can be concluded that the ovoid emergence profile restoration design can improve peri-implant soft tissue without the need for temporary restorations or peri-implant mucogingival surgery.</p>","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 2","pages":"96-101"},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Regenerative Effects of Amnion-Chorion Membrane on Bone Marrow Derived Stem Cells.","authors":"Halide Namli Kilic, Yusuke Hamada, Kentaro Imamura, Chandni Batra, Chandler L Walker","doi":"10.1563/aaid-joi-D-24-00198","DOIUrl":"10.1563/aaid-joi-D-24-00198","url":null,"abstract":"<p><p>The objective of this in vitro study was to evaluate the possible regenerative effects of dehydrated human amnion chorion membrane (ACM) on cell proliferation, migration, and differentiation/mineralization of bone marrow-derived stem cells (BMSCs). The dehydrated human ACM has been commonly used in periodontal regeneration and ridge augmentation procedures due to its membrane properties and growth factors. For the study, commercially available bone marrow-derived stem cells were thawed, cultured, and exposed to different concentrations of amnion-chorion membrane extract (50, 100, 200, 500, and 1000 μg/mL) in mesenchymal stem cell basal media. Cell proliferation was analyzed using the WST-1 assay, migration with the scratch-wound assay, and differentiation/mineralization with Alizarin Red S staining. Two-way ANOVA was used to assess the effects of concentration and time, with pair-wise comparisons made using Fisher protected least significant difference at a 5% significance level. Results showed that the control, 50 μg/mL, and 100 μg/mL groups exhibited lower cell proliferation compared with the 500 μg/mL and 1000 μg/mL groups. Lower concentrations also displayed reduced cell migration compared with the higher concentrations. In the mineralization assay, the control, 200 μg/mL, and 500 μg/mL groups exhibited lower cell mineralization compared with 1000 μg/mL. Temporally, shorter durations showed higher levels of cell migration and lower levels of cell mineralization. Overall, the use of amnion-chorion membrane positively affected cell proliferation, migration, and mineralization, with increased concentrations of amnion-chorion membrane extract yielding greater benefits. This study indicates that amnion-chorion membrane may enhance stem cell activities due to the presence of growth factors in the membrane. These findings are preliminary and must be interpreted cautiously. Further in vivo and clinical studies are necessary to validate these observations.</p>","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 2","pages":"144-150"},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Malin Olsson Malm, Torsten Jemt, Ricardo Trindade, Victoria Franke Stenport
{"title":"Gene Expression in Peri-Implant Bone with Severe Bone Loss: A Pilot Study Using Human Biopsies.","authors":"Malin Olsson Malm, Torsten Jemt, Ricardo Trindade, Victoria Franke Stenport","doi":"10.1563/aaid-joi-D-24-00233","DOIUrl":"10.1563/aaid-joi-D-24-00233","url":null,"abstract":"<p><p>Peri-implant bone loss is a complication around osseointegrated dental implants. In severe cases, it can lead to implant loosening. The etiology and the process of bone loss are still not fully understood. No published studies have analyzed cytokines in human peri-implant bone biopsies with severe bone loss. This study compares the expression of a selected panel of genetic markers from human bone biopsies and peri-implant crevicular fluid (PICF) surrounding dental implants with severe bone loss with biopsies from unaffected bone in the same patients. Nine patients planned for implant removal due to severe bone loss were included. The PICF samples were collected with paper points from the implant sites. From each patient, 1 sample of bone adjacent to the implant and 1 sample of unaffected bone were harvested. The samples were processed and analyzed with quantitative polymerase chain reaction. Expression of proinflammatory markers and markers for bone resorption and tissue degradation was upregulated in bone loss sites compared with unaffected bone. Although the results from PICF were similar, cautious interpretation is needed due to the pilot characteristics of the study. The results indicate that the immune system is active in inflammation and tissue degradation in the bone surrounding implants with severe bone loss. The gene expression findings from implant sites with severe bone loss reflected the clinical situation well-demonstrated by upregulated bone resorption markers and proinflammatory markers compared with unaffected bone. Further research is required to confirm these findings and explore the factors involved in severe bone loss around dental implants.</p>","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 2","pages":"123-131"},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abbas Zahoui, Edmara T P Bergamo, Paulo G Coelho, Ernesto B Benalcázar-Jalkh, Larissa M M Alves, Marco A M A Alves Junior, Lukasz Witek, Leonardo R Bonjardim, Yu-Chi Cheng, Estevam A Bonfante
{"title":"Osseodensification in Different-Dimension Dental Implants: A Split-Mouth Clinical Study.","authors":"Abbas Zahoui, Edmara T P Bergamo, Paulo G Coelho, Ernesto B Benalcázar-Jalkh, Larissa M M Alves, Marco A M A Alves Junior, Lukasz Witek, Leonardo R Bonjardim, Yu-Chi Cheng, Estevam A Bonfante","doi":"10.1563/aaid-joi-D-25-00037","DOIUrl":"10.1563/aaid-joi-D-25-00037","url":null,"abstract":"<p><p>The purpose of this study was to compare the insertion torque (IT) and temporal implant stability quotients (ISQ) of different-dimension dental implants placed using subtractive drilling (SD) or osseodensification instrumentation (OD). Twenty-three patients with edentulous spaces received at least 2 implants. Narrow or regular-diameter implants as well as short or regular-length implants were placed in the anterior or posterior maxilla. A split-mouth model was used with 105 implants placed. After osteotomies were performed following the manufacturer's recommendation, IT was recorded with a torque indicator, and ISQ with resonance frequency analysis was immediately performed after surgery and then weekly up to 6 weeks and at 10 weeks. IT data were analyzed using linear mixed models, whereas ISQ data were analyzed using repeated measures analysis of variance and Tukey tests. Multivariate regression models were used to assess correlations between changes in IT, ISQ, and covariates. The study included 11 females and 12 males (mean age 60.5 ± 14 years). Within the studied cohort, OD was associated with higher IT values than SD across the evaluated implant dimensions and sites. ISQ values were also higher in the OD group during the first 2 weeks. In multivariate regression, increased IT was correlated with implants placed in the anterior maxilla, regular diameter, and use of OD drilling. Whereas the investigated factors did not affect the baseline ISQ value, an increased ISQ during the early healing process was correlated with implants placed in the anterior maxilla and the use of an OD bur. Within the limitations of this study, OD demonstrated higher IT and early ISQ values compared with SD independent of implant dimension or surgical site. These findings suggest a potential impact of drilling technique on early implant stability within the study's parameters. Additional studies with larger and more diverse samples are needed to explore clinical relevance.</p>","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 2","pages":"113-122"},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Particulate Bone Grafts vs Split Bone Cortical Plates: Resorbable and Nonresorbable Membranes in Vertical Augmentation.","authors":"Farhan Durrani, Aishwarya Pandey, Rashika M, Shraddha Shilpi, Sakshi Agarwal, Mahendra Gawade","doi":"10.1563/aaid-joi-D-25-00062","DOIUrl":"10.1563/aaid-joi-D-25-00062","url":null,"abstract":"<p><p>This study aimed to evaluate vertical bone gain in the anterior edentulous mandible using the split cortical bone plate technique with 2 different graft and membrane combinations: autogenous particulate grafts with titanium-reinforced polytetrafluoroethylene membrane (T1) and a mixture of autogenous and xenograft particulate grafts with a collagen membrane (Bio-Gide) (T2). Twenty-two patients presenting with severe vertical alveolar ridge atrophy were randomly allocated into 2 equal groups with 11 participants in each group. Cone beam computerized tomography was used to assess vertical bone gain and crestal bone loss at 6 months, 1 year, and 5 years postgrafting. Keratinized tissue width and peri-implant probing depth were also measured at the same intervals to evaluate long-term soft tissue stability and peri-implant health. Whereas both groups demonstrated comparable vertical bone gain, the T1 group exhibited better maintenance of keratinized gingiva. It reduced crestal bone loss over time, suggesting the clinical utility of nonresorbable membranes in enhancing soft and hard tissue outcomes in complex augmentation cases.</p>","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 2","pages":"132-143"},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anderson Jãna Rosa, Aldir Nascimento Machado, Hariton de Souza Mesquita, Valquiria Quinelato, Lívia Ramalho Crescencio, Emanuelle Stellet Lourenço, Rafael Monte Alto, Bruna Ghiraldini, Michel Aislan Dantas Soares, Priscila Ladeira Casado
{"title":"Guided Bone Regeneration and Connective Tissue Graft With Implant Placement in Critical Bone Defect Ridge: A 10-Year Case Report Follow-Up.","authors":"Anderson Jãna Rosa, Aldir Nascimento Machado, Hariton de Souza Mesquita, Valquiria Quinelato, Lívia Ramalho Crescencio, Emanuelle Stellet Lourenço, Rafael Monte Alto, Bruna Ghiraldini, Michel Aislan Dantas Soares, Priscila Ladeira Casado","doi":"10.1563/aaid-joi-D-24-00174","DOIUrl":"10.1563/aaid-joi-D-24-00174","url":null,"abstract":"<p><p>Implantology plays an important role in oral rehabilitation, but sometimes requires supplementary procedures to restore both functional and aesthetic parameters. The presence of alveolar bone and keratinized soft tissue is crucial for achieving an aesthetically pleasing result when installing an implant. However, the early loss of a tooth affects the anatomy of the remaining periodontal tissues, making it challenging to achieve the clinical results desired by both the patient and the professional. The rehabilitation of the dental arch with osseointegrated implants enables the improvement of patients' quality of life, complemented by the advent of guided bone regeneration (GBR), which provides an excellent alternative for reestablishing bone tissue, thereby allowing the implant to be fully integrated and maintained during functional loading. The evolution in the development of biomaterials and techniques related to GBR has revolutionized this therapeutic modality, thus facilitating the clinical resolution of cases with tissue deficiencies. This report presents a clinical case description outlining the methods, techniques, and materials of choice for the placement of a single implant, utilizing GBR with bovine xenogeneic bone graft and connective tissue graft via a tunneling technique. The execution of the planned procedures resulted in a satisfactory outcome for the patient. It returned functionality and aesthetics, demonstrating that they are effective alternatives capable of success in cases of bone resorption in critical areas. Guided bone regeneration improved peri-implant tissue maintenance, increasing prognosis during a 10-year follow-up.</p>","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 2","pages":"102-112"},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reflections: \"Comparison of the Operational Difficulty and Patient-Related Outcomes for Removing Displaced Dental Implants or Tooth Roots Into the Maxillary Sinus\".","authors":"Jiayi Chen","doi":"10.1563/aaid-joi-D-25-00220","DOIUrl":"https://doi.org/10.1563/aaid-joi-D-25-00220","url":null,"abstract":"","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 2","pages":"84"},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implant Insertion in the Presence of Bone Islands in the Maxillary Sinus: A Case Report.","authors":"Jinlang Xue, Qing Fang, Shuai Hu, Jianxiang Tao","doi":"10.1563/aaid-joi-D-24-00132","DOIUrl":"10.1563/aaid-joi-D-24-00132","url":null,"abstract":"<p><p>Bone islands in the maxillary sinus are rare, and no established guidelines exist for implant surgery in their presence. This case report presents an approach to implant surgery utilizing bone islands in the maxillary sinus. In this case, we utilized the bone island, performed osteotome sinus floor elevation combined with concentrated growth factor (CGF), and simultaneously inserted a Straumann Soft Tissue Level implant for a 56-year-old male patient. Based on 1-year follow-up examinations and cone beam computed tomography (CBCT) images, the approach yielded favorable outcomes. Utilizing bone islands in the maxillary sinus during implant surgery appears effective, but longer-term follow-up and additional cases are needed to validate this approach.</p>","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 2","pages":"85-88"},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tooth Transplantation and a Root Submergence Technique After Enucleation of Multiple Continuous Radicular Cysts for Implant Treatment: A Case Report.","authors":"Noboru Katayama, Daisuke Ueno, Tomohiro Ishikawa","doi":"10.1563/aaid-joi-D-25-00093","DOIUrl":"10.1563/aaid-joi-D-25-00093","url":null,"abstract":"<p><p>When a radicular cyst-involved tooth is challenging to save, tooth extraction and cyst enucleation are required. Since only thin facial bone is present on the coronal side of cystic defects, bundle bone loss and continuity of the cystic cavity after tooth extraction may result in extensive vertical bone defects. To prevent major bone augmentation, the following procedure was performed: the left maxillary incisor (#9), which exhibited apical lesions was extracted, while the right maxillary incisor (#8), despite having a healthy periodontal ligament but being difficult to save, was transplanted into the extraction socket of the left incisor (#9). After 5 months, the bone defect had completely regenerated without any resorption of the facial bone. The regenerated bone could be used for implant placement without exposure to the implant's rough surface. In addition, the alveolar bone and alveolar contour regenerated by the tooth transplantation showed no significant decrease even 2 years after the installation of the final prosthesis, and they maintained their esthetic condition. The results indicate that tooth transplantation with healthy periodontal tissue helps regenerate bone defects.</p>","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 2","pages":"89-95"},"PeriodicalIF":1.3,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implementation of Evidence-Based Implant Dentistry Into Daily Practice.","authors":"J L Rutkowski","doi":"10.1563/orim-52-1-Editorial","DOIUrl":"10.1563/orim-52-1-Editorial","url":null,"abstract":"","PeriodicalId":519890,"journal":{"name":"The Journal of oral implantology","volume":"52 1","pages":"1-3"},"PeriodicalIF":1.3,"publicationDate":"2026-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}