{"title":"Comparison Between Parental Observations and Clinical Evaluation Findings in Korean Pediatric Patients With Intermittent Exotropia.","authors":"Wonyung Son, Won Jae Kim","doi":"10.3928/01913913-20200326-02","DOIUrl":"https://doi.org/10.3928/01913913-20200326-02","url":null,"abstract":"<p><strong>Purpose: </strong>To compare parental observations with the clinical evaluation findings in pediatric patients with intermittent exotropia and evaluate the clinical factors associated with the parental observations.</p><p><strong>Methods: </strong>This prospective study included either one or both parents of pediatric patients with intermittent exotropia who visited the clinic between January and May 2019. The parental observations were assessed through a questionnaire that included questions on the age of onset, usually deviated eye, degree of awareness, and frequency of exotropia. These findings were compared with those of the clinical evaluations, including the amount of ocular deviation and level of control.</p><p><strong>Results: </strong>A total of 100 parents (mean age: 39.7 years; 78 women) of 95 pediatric patients (mean age: 8.2 years; 47 girls) with intermittent exotropia participated in the study. The parental observation and clinical evaluation findings on the usually deviated eye showed good concordance (74%). The degree of parental awareness did not show any association with the amount of deviation. However, it showed a statistically significant increase associated with the worsening level of distance control (P = .04). The parental observations of the frequency of exotropia significantly increased with the worsening of the level of near (P = .037) and overall (P = .019) control.</p><p><strong>Conclusions: </strong>Parental observations are more likely to correlate with the level of control than with the amount of ocular deviation in pediatric patients with intermittent exotropia. [J Pediatr Ophthalmol Strabismus. 2020;57(3):199-203.].</p>","PeriodicalId":519537,"journal":{"name":"Journal of Pediatric Ophthalmology and Strabismus","volume":" ","pages":"199-203"},"PeriodicalIF":1.2,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37973900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Spot Vision Screener: A Major Impact in Pediatric Ophthalmology Practices.","authors":"Leonard B Nelson","doi":"10.3928/01913913-20200413-01","DOIUrl":"https://doi.org/10.3928/01913913-20200413-01","url":null,"abstract":"","PeriodicalId":519537,"journal":{"name":"Journal of Pediatric Ophthalmology and Strabismus","volume":" ","pages":"145"},"PeriodicalIF":1.2,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37975958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jamie H Choi, Wasim A Samara, Adam E Pflugrath, William H Benson
{"title":"Painful Proptosis in a 12-Year-Old Boy.","authors":"Jamie H Choi, Wasim A Samara, Adam E Pflugrath, William H Benson","doi":"10.3928/01913913-20200115-01","DOIUrl":"https://doi.org/10.3928/01913913-20200115-01","url":null,"abstract":"","PeriodicalId":519537,"journal":{"name":"Journal of Pediatric Ophthalmology and Strabismus","volume":" ","pages":"204"},"PeriodicalIF":1.2,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37973901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yinglei Zhang, Dan Li, Qiang Lu, Yu Du, Yi Lu, Xiangjia Zhu
{"title":"Proliferative Status in the Aqueous Humor of Eyes With Congenital Cataract.","authors":"Yinglei Zhang, Dan Li, Qiang Lu, Yu Du, Yi Lu, Xiangjia Zhu","doi":"10.3928/01913913-20200224-01","DOIUrl":"https://doi.org/10.3928/01913913-20200224-01","url":null,"abstract":"<p><strong>Purpose: </strong>To measure the concentrations of growth factors in the aqueous humor of patients with congenital cataract and to investigate the biological effects of a selected cytokine (fibroblast growth factor 4 [FGF4]) on cell proliferation, migration, and transformation.</p><p><strong>Methods: </strong>In the aqueous humor obtained from 55 eyes with congenital cataract and 55 eyes with age-related cataract, 40 growth factors were screened and selected cytokines were confirmed with enzyme-linked immunosorbent assays. After the addition of various concentrations of FGF4 (0, 2.5, 15, or 50 ng/mL) to the incubation medium, cellular functions were evaluated.</p><p><strong>Results: </strong>The concentration of FGF4 was significantly higher in the aqueous humor of patients with congenital cataract than in that of patients with age-related cataract. The human SRA01/04 lens epithelial cell line was treated with FGF4 and the cell proliferation increased significantly both dose- and time-dependently. The wound healing assay and Transwell migration assay revealed a significant increase in the migration capacity of the SRA01/04 cell line treated with 15 or 50 ng/mL of FGF4 compared with that of control cells. The intensity of immunofluorescent staining for α-smooth muscle actin increased significantly in the SRA01/04 cell line when treated with FGF4. Cytoskeletal protein (F-actin) staining showed that changes of cell morphology were induced in primary lens epithelial cells by FGF4.</p><p><strong>Conclusions: </strong>This study provides a comprehensive profile of growth factors in congenital cataract. FGF4 induced cellular changes, and may have utility as a biomarker to predict the formation of visual axis opacification. [J Pediatr Ophthalmol Strabismus. 2020;57(3):159-168.].</p>","PeriodicalId":519537,"journal":{"name":"Journal of Pediatric Ophthalmology and Strabismus","volume":" ","pages":"159-168"},"PeriodicalIF":1.2,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37973895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Practice Patterns in the Surgical Management of Pediatric Traumatic Cataracts.","authors":"Angela Y Zhu, Courtney L Kraus","doi":"10.3928/01913913-20200304-01","DOIUrl":"https://doi.org/10.3928/01913913-20200304-01","url":null,"abstract":"<p><strong>Purpose: </strong>To facilitate the development of standardized guidelines for the surgical management of patients with pediatric traumatic cataracts by assessing current ophthalmologists' practice patterns.</p><p><strong>Methods: </strong>This was a cross-sectional, observational, and retrospective study. A 24-question electronic survey of current practices pertaining to the surgical management of pediatric traumatic cataracts was sent to pediatric ophthalmologists worldwide. Preferences for pre-operative evaluation, surgical timing and techniques, and postoperative management were analyzed.</p><p><strong>Results: </strong>Of the 56 respondents, 62.5% practiced in academic settings. Of the 49 respondents (87.5%) who performed pediatric ruptured globe repair, 41.7% would perform simultaneous cataract extraction if anterior capsular violation existed, whereas 4.1% would do so without capsular violation (P < .001). Most respondents (50.9%) would remove visually significant cataracts within 4 weeks in patients within the amblyogenic age range (P = .02), whereas 63.6% would wait longer outside the amblyogenic range. Preferences for intraocular lens selection, primary posterior capsulotomy, and timing of amblyopia therapy differed.</p><p><strong>Conclusions: </strong>Individual management practices regarding pediatric traumatic cataracts vary depending on associated globe injuries and patient age. Trends exist in surgical planning, intraoperative techniques, and visual rehabilitation methods, but no single approach has achieved complete unanimity. Therefore, further investigation into optimal timing and the extent of surgical intervention, refractive correction, and postoperative care is necessary prior to developing evidence-based guidelines for enhancing visual outcomes in this population. [J Pediatr Ophthalmol Strabismus. 2020;57(3):190-198.].</p>","PeriodicalId":519537,"journal":{"name":"Journal of Pediatric Ophthalmology and Strabismus","volume":" ","pages":"190-198"},"PeriodicalIF":1.2,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37973899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cyril Archambault, Assia Mekliche, Jordan Isenberg, Nicole Fallaha, Patrick Hamel, Rosanne Superstein
{"title":"Pediatric Ocular Injuries: A 3-Year Follow-up Study of Patients Presenting to a Tertiary Care Clinic in Canada.","authors":"Cyril Archambault, Assia Mekliche, Jordan Isenberg, Nicole Fallaha, Patrick Hamel, Rosanne Superstein","doi":"10.3928/01913913-20200326-01","DOIUrl":"https://doi.org/10.3928/01913913-20200326-01","url":null,"abstract":"<p><strong>Purpose: </strong>To identify age groups or activities at risk for ocular injuries to provide parents, sports teams, schools, and hospitals with the appropriate tools for prevention strategies.</p><p><strong>Methods: </strong>A retrospective chart review was conducted of all trauma-related cases from 2013 to 2015 and data were obtained with the use of an electronic medical record. All patients younger than 18 years who presented to the ophthalmology clinic with traumatic ocular injuries were included.</p><p><strong>Results: </strong>A total of 409 patients met the inclusion criteria and all were included in this study. The mean age was 7.74 years. Boys were injured more frequently than girls (60.4%). Most ocular injuries occurred between the ages of 2 and 9 years (51.8%). The most common sport was soccer, followed by ball/ice hockey, which differs from previous study findings. This may highlight the increasing popularity of soccer and the risk it may entail. Injuries occurred at home in 23.2% of cases. Final visual acuity was 20/40 or better in 77% of patients.</p><p><strong>Conclusions: </strong>These findings are comparable to the authors' previous data and to those of the only other Canadian study done on this subject, with the exception of an increased incidence of soccer-related injuries in the current cohort, highlighting an area important to future prevention strategies. [J Pediatr Ophthalmol Strabismus. 2020;57(3):185-189.].</p>","PeriodicalId":519537,"journal":{"name":"Journal of Pediatric Ophthalmology and Strabismus","volume":" ","pages":"185-189"},"PeriodicalIF":1.2,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37973898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maureen E Lloyd, Frederick M Wang, Barry N Wasserman, Leonard B Nelson
{"title":"Management Issues in Adult Strabismus.","authors":"Maureen E Lloyd, Frederick M Wang, Barry N Wasserman, Leonard B Nelson","doi":"10.3928/01913913-20200330-01","DOIUrl":"https://doi.org/10.3928/01913913-20200330-01","url":null,"abstract":"","PeriodicalId":519537,"journal":{"name":"Journal of Pediatric Ophthalmology and Strabismus","volume":" ","pages":"140-143"},"PeriodicalIF":1.2,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37975520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parthopratim Dutta Majumder, Saurabh Mistry, Sudharshan Sridharan, Amala Elizabeth George, Vineeta Rao, Sudha K Ganesh, Jyotirmay Biswas
{"title":"Pediatric Sympathetic Ophthalmia: 20 Years of Data From a Tertiary Eye Center in India.","authors":"Parthopratim Dutta Majumder, Saurabh Mistry, Sudharshan Sridharan, Amala Elizabeth George, Vineeta Rao, Sudha K Ganesh, Jyotirmay Biswas","doi":"10.3928/01913913-20200219-01","DOIUrl":"https://doi.org/10.3928/01913913-20200219-01","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the clinical profile of sympathetic ophthalmia among the pediatric age group.</p><p><strong>Methods: </strong>Retrospective review of patients 18 years and younger with sympathetic ophthalmia seen in a tertiary eye care center between 1997 and 2017.</p><p><strong>Results: </strong>Of 20 patients included in the study, 70% were male. The most common inciting event for sympathetic ophthalmia was trauma (85%), followed by vitreoretinal surgery (15%). All patients were treated with systemic steroids. Seventeen patients received additional corticosteroid-sparing immunosuppressive agents, and 4 patients (20%) required more than one immunosuppressive agent. Azathioprine was the most commonly used corticosteroid-sparing immunosuppressive agent. The most common complications were cataract (50%) and ocular hypertension (30%). The mean presenting best corrected visual acuity in the sympathizing eye was 1.15 ± 0.99 logarithm of the minimum angle of resolution (logMAR), which improved to 0.54 ± 1.00 logMAR following treatment. Visual outcome was good (6/12 or better) in 70% of the sympathizing eyes, and 3 of the exciting eyes in the current study had good visual outcomes after the treatment.</p><p><strong>Conclusions: </strong>Prompt and effective management with corticosteroid-sparing immunosuppressive therapy in children with sympathetic ophthalmia allows favorable control of the disease and retention of good visual acuity. [J Pediatr Ophthalmol Strabismus. 2020;57(3):154-158.].</p>","PeriodicalId":519537,"journal":{"name":"Journal of Pediatric Ophthalmology and Strabismus","volume":" ","pages":"154-158"},"PeriodicalIF":1.2,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37975959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Madison E Kerley, Simra Ahmed, Aparna Ramasubramanian
{"title":"Bilateral Chorioretinitis From NOMID Disease.","authors":"Madison E Kerley, Simra Ahmed, Aparna Ramasubramanian","doi":"10.3928/01913913-20190220-01","DOIUrl":"https://doi.org/10.3928/01913913-20190220-01","url":null,"abstract":"","PeriodicalId":519537,"journal":{"name":"Journal of Pediatric Ophthalmology and Strabismus","volume":" ","pages":"204"},"PeriodicalIF":1.2,"publicationDate":"2019-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37263636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}