Life and Science最新文献

{"title":"Comparison of Efficacy of Ciprofloxacin and Co-Trimoxazole in Escherichia Coli Urinary Tract Infection","authors":"Muhammad Ayaz, Sayed Ali Zeeshan Kausar, Muhammad Alamgir, Shafiq Muhammad, Fayaz Muhammad Khan, Sami Ullah","doi":"10.37185/lns.1.1.595","DOIUrl":"https://doi.org/10.37185/lns.1.1.595","url":null,"abstract":"Objective: To compare the efficacy of ciprofloxacin and co-trimoxazole in urinary tract infection due to Escherichia Coli.Study Design: A cross- sectional study. Place and Duration of Study: This study was conducted at the Department of Medicine, Muhammad TeachingHospital (MTH), Peshawar, Pakistan from 1 July 2022 to 31 December 2022.Methods: Patients were randomly and consecutively assigned to either group by using lottery method (double blind). A total of 194 patients diagnosed with urinary tract infection due to E coli were randomly divided into two groups, 97 patients in each group, using 54% efficacy of ciprofloxacin, 74% efficacy of Co-Trimoxazole, 95% confidence level, and 90% power of test, using WHO software. “Group-A' for Ciprofloxacin 500mg BD and th 'Group-B' for Co-Trimoxazole 960mg BD. All the recruited patients were followed up after the 48 hour of their treatment and results were recorded. The chi-Square test was applied to compare the efficacy results of both drugs where a PValue < 0.05 was considered as significant value.Results: The mean age of group A participants were 48.4 + 11.1 years, whereas, in group B it was 48.2 + 11.5 years. There were 69.1% males and 30.9% females in group A compared to 80.4% males and 19.6% females ingroup B. After the 48 hour of end treatment, efficacy was 79.3% and 50.5%, in groups A and B respectively (p-value = 0.000).Conclusion: As compared to Cotrimoxazole, Ciprofloxacin is more effective in treating E. coli-caused urinary tract infections. \u0000How to cite this: Ayaz M, Kausar SAZ, Alamgir M, Muhammad S, Khan FM, Ullah S. Comparison of Efficacy of Ciprofloxacin and CoTrimoxazole in Escherichia Coli Urinary Tract Infection. Life and Science. 2024; 5(2): 151-159. doi: http://doi.org/10.37185/LnS.1.1.595 \u0000 ","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":" 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141129836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Risk of Atrial Fibrillation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease","authors":"Muhammad Aneel Razzaq, Muhammad Atif, Ubaid Ullah, Mohsin Mehmood, Muhammad Irfan, Kashif Sardar","doi":"10.37185/lns.1.1.487","DOIUrl":"https://doi.org/10.37185/lns.1.1.487","url":null,"abstract":"Objective: To evaluate the role of acute exacerbation of COPD in the risk of atrial fibrillation. Study Design: Cross sectional study design.Place and Duration of Study: The study was conducted at Bakhtawar Amin Hospital Multan and Recep Tayyip Erdogan Hospital Muzaffargarh, Pakistan from March 2022 to March 2023.Methods: The patients with acute, hypercapnic chronic obstructive pulmonary disease(COPD) exacerbation were included in the study. A total of 200 patients were analyzed. Baseline data including demographic and clinical details, blood tests, ABG, systolic and diastolic blood pressure, ECG, pulmonary function test, and transthoracic echocardiography were recorded.Results: Of 200 patients, 40(20%) had an episode of paroxysmal atrial fibrillation (AF). Atrial fibrillation was more prevalent in cases with lower FEV1 (P<.05). In addition, it was also more common in cases with higher PaCO2 (P<.05). Atrial Fibrillation was significantly higher in cases with larger LA diameters (34.1 ± 2.3 mm vs 46.1 ± 2.3 mm, P<.05), area (22.8 ± 4.1 cm2 vs 34.1 ± 5.1 cm2, P<.05) and higher PASP (36.1 mmHg ± 2.2 vs 46.4 mmHg ± 3.7, P<.05). RA area was larger in patients with AF and COPD compared to those without AF (25.6 ± 5.1cm2 vs 30.2 ± 6.4 cm2, P<0.05). These findings suggest COPD patients are at increased risk of AF and require measures to reduce the risk. These data will be helpful for further investigation and development of strategies to prevent AF morbidities in COPD patients.Conclusion: In patients with acute exacerbations of chronic obstructive pulmonary disease, blood gas fluctuations, hemodynamic alterations, and abnormal pulmonary functions can lead to an increased risk of atrial fibrillation.  \u0000How to cite this: Razzaq MA, Atif M, Ullah U, Mehmood M, Irfan M, Sardar K. The Risk of Atrial Fibrillation in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Life and Science. 2024; 5(2): 132-137. doi: http://doi.org/10.37185/LnS.1.1.487","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":" 45","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141129790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Postoperative Analgesia with Rectal Placement of Diclofenac Sodium in Patients Undergoing Gynecological and Obstetrical Surgeries under General Anesthesia","authors":"Riffat Saeed, Anam Mahboob, Syed Mahmood Ali, Amer Latif, Tooba Ammar, Irfan Ali Kakepotto","doi":"10.37185/lns.1.1.515","DOIUrl":"https://doi.org/10.37185/lns.1.1.515","url":null,"abstract":"Objective: To determine the frequency of need for postoperative intravenous analgesia after rectal diclofenac suppository in patients undergoing lower abdominal gynecological or obstetrical surgery under general anesthesiaStudy Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the Operation Theater and Postoperative Ward of Sheikh Zayed Hospital, Lahore, Pakistan from January 2021 to July 2021.Methods: A total of 245 women undergoing gynecological and obstetrical surgeries under general anesthesia were enrolled in the study using non-probability consecutive sampling. All the participants were recruited after obtaining informed consent and meeting the inclusion criteria. All subjects had a single 100mg diclofenac suppository inserted rectally after undergoing general anesthesia, and their Visual Analog Scale (VAS) scores for postoperative analgesia were recorded immediately after surgery and again at 1, 6, and 24 hours.Results: The mean age of the patients was 37 years, with a standard deviation of 6.2. The mean VAS (Visual Analog Scale) scores at 1, 6, 12, and 24 hours were 3 (±1.24), 5 (±1.46), 7 (±1.93), and 6 (±2.14), respectively. The need for rescue analgesia was reported in 15.9% of cases at 1 hour, 37.1% at 6 hours, 82% at 12 hours, and 68.2% at 24 hours.Conclusion: The administration of diclofenac via rectal placement led to a notable decrease in Visual Analog Scale scores and a lower incidence of needing additional pain relief within the first 6 hours after surgery. \u0000How to cite this: Saeed R, Mahboob A, Ali SM, Latif A, Ammar T, Kakepotto IA. Requirement of Postoperative Analgesia after Per Rectal Placement of Diclofenac Sodium in Patients Undergoing Gynecological and Obstetrical Surgeries under General Anesthesia. Life and Science. 2024; 5(1): 120-125. doi: http://doi.org/10.37185/LnS.1.1.515","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":"46 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140505940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Uterine Artery Embolization on Heavy Menstrual Bleeding in Patients with Leiomyomata","authors":"Salisa Hassan Khan, Manzoor Ahmad, Zainab Abbas Mirza, Atif Sheraz, Mahpara Tariq","doi":"10.37185/lns.1.1.475","DOIUrl":"https://doi.org/10.37185/lns.1.1.475","url":null,"abstract":"Objective: To compare the effect of uterine artery embolization and medical management on heavy menstrual bleeding in patients managed for uterine fibroids. Study Design: Comparative Cross-sectional Study. Place and Duration of Study: The study was conducted at the Department of Gynecology and Obstetrics, Pak Emirates Military Hospital (PEMH) Rawalpindi, Pakistan fromAugust 2021 to March 2023.Methods: Women between the ages of 35 and 50 years who presented with heavy menstrual bleeding and were diagnosed with leiomyomata were included in this study. They were divided into two groups via block randomization. Group-I underwent uterine artery embolization while group-II received medical treatment (gonadotropin-releasing hormone (GnRH) antagonist). Clinical factors like shrinkage in the size of fibroids, rise in hemoglobin levels, and pelvic pain scores were compared in both groups at the end of three months. Results: Out of 160 women recruited in the study, 52 (32.5%) were pre-menopausal, while 108 (67.5%) were peri menopausal. The mean age of patients who presented with heavy menstrual bleeding due to leiomyomata was 45.23 ±12.70 years. The mean rise in hemoglobin (p-value-0.007) and mean shrinkage size (p-value<0.001) were statistically significantly found more in patients who underwent uterine artery embolization as compared to those who took medical treatment. The mean pain score (p-value-0.01) was also found to be more in a group of patients who underwent uterine artery embolization.Conclusion: Uterine artery embolization emerged as an effective procedure for women managed for heavy menstrual bleeding due to uterine fibroids. Medical management via gonadotropin-releasing hormone (GnRH) antagonist was inferior in efficacy in terms of mean rise in hemoglobin and fibroid shrinkage.How to cite this: Khan S, Ahmad M, Mirza ZA, Sheraz A, Tariq M. The Effect of Uterine Artery Embolization on Heavy Menstrual Bleeding in Patients with Leiomyomata. Life and Science. 2024; 5(1): 27-32. doi: http://doi.org/10.37185/LnS.1.1.475","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":"35 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Binding Occupancy of Pro-Hypertrophic Transcription Factors among Cardiac Developmental Enhancers","authors":"Rabail Zehra Raza, Irfan Hussain, Fatima Akhtar, Sara Mumtaz","doi":"10.37185/lns.1.1.464","DOIUrl":"https://doi.org/10.37185/lns.1.1.464","url":null,"abstract":"Objective: To check which of the eight pro-hypertrophic transcription factors bind in abundance to a set of 140 functionally confirmed cardiac enhancers aiming to identify potential therapeutic targets for delaying the onset of cardiac hypertrophy. Study Design: Bioinformatics, in-Silico Study.Place and Duration of Study: The study was conducted at the Department of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi, Pakistan, from January 2022 to December 2022.Methods: For experimentally verified human and mouse noncoding regions with gene enhancer activity measured in transgenic mice, VISTA Enhancer Browser was used to obtain 140 cardiac-specific functionally confirmed enhancers. Among these enhancers, transcription factor binding sites were computationally mapped to assess transcription factor occupancy. The binding sites for all eight transcription factors were screened in the collective set of 140 cardiac enhancers via an in-house script. Results: In this study, among a small set of eight pro-hypertrophic transcription factors, occupancy of transcription factor HAND (Heart- And Neural Crest Derivatives-Expressed Protein) was found to be maximum in the collected pool of functionally confirmed cardiac enhancers. Conclusion: The transcription factor HAND was found to have maximum binding occupancy among a set of experimentally confirmed cardiac enhancers.How to cite this: Raza RZ, Hussain I, Akhtar F, Mumtaz S. The Binding Occupancy of Pro-Hypertrophic Transcription Factors among Cardiac Developmental Enhancers. Life and Science. 2024; 5(1): 22-26. doi: http://doi.org/10.37185/LnS.1.1.464","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Hypothyroidism-Induced Impaired Development of Neurons in Rat Offspring: Insights for Antenatal Care","authors":"Tayyaba Fahad, Shabana Ali, Tayyaba Qureshi, Noor Fatima Khan","doi":"10.37185/lns.1.1.525","DOIUrl":"https://doi.org/10.37185/lns.1.1.525","url":null,"abstract":"Objective: To determine the effect of maternal hypothyroidism on the development of neurons in the motor cortex of rat pups by using light microscopy. Study Design: Laboratory-based experimental study.Place and Duration of Study: The study was carried out in collaboration with the National Institute of Health (NIH) Islamabad and the Department of Anatomy, Islamic International Medical College, Riphah International University, Islamabad, Pakistan from March 2023 to May 2023.Methods: In this study, 24 females and 12 male Sprague dawley rats were sorted into control and hypothyroid groups. The control group received a standard diet and plain drinking water throughout the study. In contrast, the hypothyroid group had 4.5mg of propylthiouracil administered per rat per day, mixed into their drinking water. This treatment started a week before mating and continued until three weeks after delivery. Once successful mating was confirmed via vaginal plugs, gestation proceeded, and newborn pups were born after nd three weeks, having full access to maternal lactation for 21 days. On the 22 day after birth, dissection took place, and the brains of the pups were carefully removed. Coronal sections of the motor cortex were then obtained for subsequent examination.Results: The control group displayed a typical pattern of neurogenesis, characterized by the normal structure of cortical neurons. On the other hand, intracellular vacuolation, glial cell necrosis, and reduced Nissl rim thickness were statistically significant in hypothyroid group which collectively pointed to atypical neurogenesis. Conclusion: This study highlights the adverse effects of maternal hypothyroidism on the structural integrity of cortical neurons. It focuses on increasing awareness and implementing thorough prenatal healthcare strategies.How to cite this: Fahad T, Ali S, Qureshi T, Khan NF. Maternal Hypothyroidism-Induced Impaired Development of Neurons in Rat Offspring: Insights for Antenatal Care. Life and Science. 2024; 5(1): 68-74. doi: http://doi.org/10.37185/LnS.1.1.525","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":"18 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140507450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Efficacy between Myo-Inositol versus Metformin in Women with Polycystic Ovary Syndrome","authors":"Nurmeen Latif, Seema Rajar, Mehreen Yousuf, Sadaf Imtiaz, Sidrah Abbas, Zara Jamali","doi":"10.37185/lns.1.1.486","DOIUrl":"https://doi.org/10.37185/lns.1.1.486","url":null,"abstract":"Objective: To compare the effectiveness of myo-inositol versus metformin in treating women with polycystic ovary syndrome.Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the Department of Gynae Unit II, Dr. Ruth. K.M. Pfau th th Civil Hospital Karachi, Pakistan from 7 February 2019 to 6 August 2019.Methods: All eligible patients who visited the hospital were enrolled. The group-Aincluded females who received myo-inositol (n=35), whereas the group-B included females who received metformin (n=35). Females in the myo-inositol group were administered 1 gram of myo-inositol twice daily, while those in the metformin group were administered 500 mg of metformin twice daily. Regular follow-up visits were scheduled every two months, and the efficacy of the treatment was assessed after six months. Efficacy was evaluated in terms of the normalization of menstrual cycles and the achievement of ovulation.Results: The mean age in the myo-inositol and metformin groups was 23.92±3.70 and 23.68±4.23, respectively. The mean weight in the myoinositol and metformin groups was 59.23±2.07 and 61.79±5.92, respectively. Notably, the efficacy rates for the myo-inositol and metformin groups were 68.57% and 20%, respectively with p-value=0.001.Conclusion: Myo-inositol was found to demonstrate significant superiority over metformin in the treatment of polycystic ovary syndrome.How to cite this: Latif N, Rajar S, Yousuf M, Imtiaz S, Abbas S, Jamali Z. Comparison of Efficacy Between Myo-Inositol versus Metformin in Women with Polycystic Ovary Syndrome. Life and Science. 2024; 5(1): 48-53. doi: http://doi.org/10.37185/LnS.1.1.486","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness and Acceptability of Breast Reconstruction Among Women with Breast Cancer in Twin Cities of Islamabad and Rawalpindi","authors":"Mehwish Mehmood, A. Aslam, Waqas Ahmed, Sameena Aman, Ahmed Ali, Hira Feroze, Nousheen Saleem","doi":"10.37185/lns.1.1.509","DOIUrl":"https://doi.org/10.37185/lns.1.1.509","url":null,"abstract":"Objective: To determine the frequency of awareness and acceptability of breast reconstruction surgery among women in the twin cities of Islamabad and Rawalpindi.Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the Department of Plastic Surgery, Fauji Foundation Hospital, Rawalpindi, Pakistan, from October 2022 to June 2023.Methods: A total of 271 patients between 20-70 years of age with a diagnosis of breast cancer were included. Demographic details, including marital status, education, residence, occupation, family history, awareness of breast reconstruction, and source of information about breast reconstruction, were documented on a proforma. All patients received information regarding breast reconstruction, and records of the frequency of acceptability and contributing factors were made. Data analysis was carried out by using SPSS 25.0.Results: The mean age of patients was 43.41 ± 8.98 years. Out of 271 patients, 114 patients (42.1%) had an awareness of breast reconstruction. The primary source of information was the treating physician in 60 out of 114 patients (52.6%). Breast reconstruction acceptability was reported in 110 out of 271 patients (40.6%). Family support was the most common reason for acceptance in 43 out of 110 patients (39.1%).Conclusion: Efforts need to be made at the community level to educate the general population about breast cancer treatment options, including breast reconstruction. Education was significantly associated with increased awareness and acceptability for breast reconstruction. Better cosmetic outcomes and family support were the factors for increased acceptability, while financial constraints and family pressures were reasons for the vice versa.How to cite this: Mehmood M, Aslam A, Ahmed W, Aman S, Ali A, Feroze H, Saleem N. Awareness and Acceptability of Breast Reconstruction Among Women with Breast Cancer in Twin Cities of Islamabad and Rawalpindi. Life and Science. 2024; 5(1): 9-15. doi: http://doi.org/10.37185/LnS.1.1.509","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":"55 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Diagnostic Accuracy of Digital Breast Tomosynthesis in Distinguishing Malignant and Benign Breast Lesions","authors":"Kanza Afzal, Nadia Gul, Khalid Mehmood, Sobia Jawwad, Bushra Iqbal","doi":"10.37185/lns.1.1.416","DOIUrl":"https://doi.org/10.37185/lns.1.1.416","url":null,"abstract":"Objective: The study aims to determine the diagnostic accuracy of digital breast tomosynthesis in diagnosing malignant and benign lesions, keeping histopathology as the gold standard.Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the Department of Diagnostic Radiology, POF th th Hospital, Wah Cantt, Pakistan over a period of six months from 11th  July 2021 to 11th January 2022.Methods: A total of 200 women presenting with suspicion of breast malignancy were selected consecutively from the outpatient department, and Digital Breast Tomosynthesis(DBT) was performed, followed by a biopsy of the specimen to confirm the findings on histopathology. Results: The average age of the sample was 48.3 + 7.1 years, ranging between 35 and 60 years. Palpable breast lump was recorded in 44.5%, pain in 33%, and nipple discharge in 35.5%. Family history of breast Ca was present in 25.5. On Digital Breast Tomosynthesis (DBT), 58.5% of lesions were labeled as malignant, while 53.5% were labeled as malignant on follow-up histopathology. On applying the formulae for calculation, the sensitivity of DBT was found to be 86% and specificity 73.1%. The positive predictive value of the DBT is 78.6%, and the negative predictive value is 81.9%.Conclusion: In conclusion, Digital Breast Tomosynthesisis a significantly sensitive and specific tool for detecting malignant breast lesions in women suspected of breast carcinoma.How to cite this: Afzal K, Gul N, Mehmood K, Jawwad S, Iqbal B. Assessment of Diagnostic Accuracy of Digital Breast Tomosynthesis in Distinguishing Malignant and Benign Breast Lesions. Life and Science. 2024; 5(1): 3-8. doi: http://doi.org/10.37185/LnS.1.1.416 \u0000 ","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":"13 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Body Mass Index and Ankle Dorsiflexion in Planter Fasciitis Patients; Performance Perspective","authors":"Prem Lata, Shaista Hayat, Vinesh Kumar, Muhammad Faizan Hassan, Sana Batool, Khadijatul Ain Sandeela, Komal Jamil","doi":"10.37185/lns.1.1.461","DOIUrl":"https://doi.org/10.37185/lns.1.1.461","url":null,"abstract":"Objective: To determine the effects of body mass index and ankle dorsiflexion in patients with plantar fasciitis.Study Design: A cross-sectional.Place and Duration of Study: The study was carried out at the Department of Physical Therapy of the two leading tertiary care centers, Advance Orthopedic & Reconstructive Institute & Dr. Ziauddin Hospital Karachi, Pakistan from August 2022 to June 2023.Methods: Sixty-Four participants were recruited from the physical therapy departments of two tertiary care centers in Karachi by convenience sampling. The study focuses on the impact of demographics on the performance of plantar fasciitis patients. The measurement tools used in this are BMI (Body mass index), NRS (Numeric rating scale), LEFS (Lower extremity functional scale), and Goniometer. The data were analyzed by SPSS version 23.0. Results: Our findings show that plantar fasciitis is more common in the obese-II category with reference to BMI, females are more affected than males with reference to gender, the middle age group is more affected with reference to age and dorsiflexion angle of patients is less than normal range shows the directly proportional of demographics with the performance of patients with plantar fasciitis.Conclusion: Our study showed the positive effect of ankle dorsiflexion angle and BMI, gender, pain, and age on the physical performance of plantar fasciitis patients. \u0000How to cite this: Lata P, Hayat S, Kumar V, Hassan MF, Batool S, Sandeela KA, Jamil K. Effect of Body Mass Index and Ankle Dorsiflexion in Planter Fascitis Patients; Performance Perspective. Life and Science. 2024; 5(1): 113-119. doi: http://doi.org/10.37185/LnS.1.1.461","PeriodicalId":516717,"journal":{"name":"Life and Science","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140508534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}